Puberty
Articles tagged with Puberty
New UH tool measures whether lactating mothers’ psychological needs are being met
World Hormone Day 2026
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
CNIO research links fertility with immune cells in the brain
A study published in Science reveals that microglia and the protein RANK are involved in regulating the hypothalamic-pituitary-gonadal axis, which controls fertility. The research found that suppressing RANK expression led to distorted reproductive function, including reduced sex hormones and hypogonadism.
Summarizing ten years of research: new study explains why children enter puberty earlier
A new Danish study compiles ten years of research identifying several factors during pregnancy and childhood that advance the timing of puberty, including genetic predisposition, maternal health, and psychosocial stressors. The study found an average shift of about three months, affecting both physical wellbeing and later health outcomes.
Early puberty may increase the risk of poor mental wellbeing and higher consumption of alcohol, cigarettes and drugs
A new study from Aarhus University finds that early puberty is associated with an increased risk of general psychological distress, psychiatric diagnoses, and the use of psychiatric medication. Girls who enter puberty early may have twice the risk of receiving psychiatric medication for mental health conditions compared to their peers.
European Society of Endocrinology leads global call to raise awareness of hormone health on World Hormone Day 2026
The European Society of Endocrinology is launching a new campaign to raise awareness about the importance of hormone health. The #BecauseHormonesMatter initiative aims to improve public understanding of hormones and promote practical steps for better hormone health, following the success of last year's campaign.
Grandfather’s environmental chemical exposures may influence when girls get first period
A new study presents preliminary data suggesting that grandparents' exposure to endocrine-disrupting chemicals may impact the age when girls get their first period. The research found that certain chemicals in both mothers and fathers were linked to earlier puberty, with stronger effects seen in granddaughters.
Age at woman’s first period can offer clues about long-term health risks
A study of over 7,600 Brazilian women found that early menarche increases risk for metabolic and heart problems, while late menarche may protect against obesity but increase certain heart issues. Understanding age at first period can help doctors identify high-risk patients and guide personalized screening and prevention efforts.
Consuming certain sweeteners may increase risk of early puberty
A study found that consuming aspartame, sucralose, glycyrrhizin and added sugars may increase the risk of early puberty in children, especially those with genetic traits. This association was strongest for central precocious puberty, a condition linked to emotional distress and metabolic disorders.
Popular teen movies reel back from visible signs of puberty
A new study analyzed 53 popular films and found that most depict idealized and aspirational views of puberty, romance, and relationships. This can lead to a disconnect between on-screen representations and real-life experiences, influencing how teens perceive themselves and their place in the world.
Researchers identify a dual origin of cells controlling puberty and reproduction
Gonadotroph cells controlling puberty and reproduction originate from two separate populations, with the majority produced after birth. This finding could aid in understanding and treating disorders impacting puberty and fertility.
Early puberty increases risk of overweight later in life for girls
Girls who enter puberty early have a higher BMI before, during, and after puberty, increasing the risk of overweight later in life. The study found that biological differences between sexes make girls more vulnerable to this impact.
New study discovers link between delayed puberty and early-onset type 2 diabetes for the first time
A new study has discovered a link between delayed puberty and an increased risk of developing type 2 diabetes in boys. According to the research, adolescent boys who experience delayed puberty are 37% more likely to develop type 2 diabetes in early adulthood, regardless of their weight or socio-economic status.
Early-life growth proved important for height in puberty and adulthood
Research found that early-life growth plays a significant role in determining final adult height, accounting for about 67% of the variation. Childhood growth also accounted for a substantial proportion of the difference in adult height.
Antibiotics taken during infancy linked to early puberty in girls
Research suggests that antibiotics taken during infancy, especially in the first three months, may lead to earlier onset of puberty in girls. The study, which analyzed data on over 322,000 children in South Korea, found a significant association between early antibiotic exposure and increased risk of central precocious puberty.
A healthy diet in childhood is linked to starting menstrual periods later, regardless of BMI or height
A study published in Human Reproduction found that healthy childhood diets are associated with delayed onset of menstruation, independent of body mass index (BMI) or height. The research suggests that a diet high in fruits, vegetables, and whole grains may help reduce the risk of chronic diseases such as diabetes and breast cancer.
The puberty talk: Parents split on right age to talk about body changes with kids
A national poll suggests parents are evenly split on when to start talking about puberty, with some fearing embarrassment or saying the wrong thing. Parents' own experiences may influence their approach, with many having had limited discussions themselves.
Puberty triggers brain rewiring in genetic condition tied to autism
Researchers have found that puberty triggers significant changes in brain connectivity patterns in individuals with a rare genetic disorder tied to autism. The study suggests that synaptic dysfunction during development may contribute to the condition's behavioral challenges.
Communication between body muscle and the brain influences fertility, study finds
Researchers at McGill University found that a protein produced in muscles helps manage the release of follicle-stimulating hormone (FSH), which promotes egg maturation. Lowering myostatin levels delayed puberty and reduced fertility, while restoring it boosted FSH levels.
The gold standard of a randomized controlled study among NYC girls indicates that a book on puberty can lead to significant gains in knowledge and positive health outcomes
A randomized controlled study among NYC girls found that reading a book on puberty can lead to increased knowledge and positive attitudes towards physical activity during periods. The study, published in BMC Public Health, suggests that targeted puberty education can have significant impacts on young girls' health outcomes.
Save the date: European Society of Endocrinology (ESE) and ESE Foundation announce inaugural World Hormone Day
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Salmon genes unlock secrets of puberty and evolution
Researchers discovered a single gene, vgll3, regulating thousands of genes in salmon sexual maturation, influencing traits like reproductive cell development and growth patterns. This study sheds light on how genetic variation can impact complex traits like puberty onset and has significant implications for managing wild populations.
Hormone therapy reshapes the skeleton in transgender individuals who previously blocked puberty
New research reveals that hormone therapy can alter skeletal size and shape in transgender individuals who previously suppressed puberty. Transgender men treated with puberty blockers and hormone therapy have broader shoulders and a smaller pelvic inlet, while women have a larger pelvis after treatment from early puberty.
Excessive screen time linked to early puberty and accelerated bone growth
Research found that prolonged blue light exposure accelerates bone growth and bone age, leading to early puberty in rats. This could have implications for children's height and skeletal development in adulthood.
First nationwide study discovers link between delayed puberty in boys and increased hospital visits
A nationwide study found that Swedish young men with delayed puberty are more likely to use healthcare services later in life. They were also more likely to be admitted to hospital and prescribed medications, indicating potential long-term health consequences.
Teenage hormonal shift surprises scientists – opposite impacts on kidney injury
Researchers found that female sex hormones may increase susceptibility to kidney injury during puberty, contradicting the protective effects seen in adulthood. The study suggests that developmental changes driven by the hormonal surge in puberty may override the benefits of female sex hormones later in life.
Large variation in how girls grow after their first period
A study of 793 girls found significant variation in height growth after their first period, with most not reaching the expected 6-8 cm. Early onset of menstruation is linked to greater growth, while late onset is associated with shorter final height. Childhood BMI also plays a role in determining menarche age and subsequent growth.
Research reveals reality of Ice Age teen puberty
Researchers analyzed ancient human bones to assess puberty stages in 13 Ice Age teens, ages 10-20. Most entered puberty at 13.5 and reached adulthood between 17-22 years old.
Only children enter puberty significantly earlier than children with siblings
A Danish study reveals that only children and those with half- or step-siblings enter puberty significantly earlier than children with biological siblings. The study found a two-month difference in girls' pubertal timing and a smaller but still significant gap for boys.
Girls may start puberty early due to chemical exposure
Research suggests that exposure to musk ambrette and cholinergic agonists can trigger early female puberty by activating key hormone receptors. This study highlights the importance of regulating personal care products and environmental chemicals to mitigate potential health risks.
Boys with higher levels of environmental pollutants enter puberty later
Research from the University of Bergen found that boys with higher per- and polyfluoroalkyl substances (PFAS) levels have smaller testicular volume and lower testosterone levels compared to their peers. PFAS exposure is a significant concern for pubertal development, highlighting the need for further research into its mechanisms.
Trajectory of type 1 diabetes risk shifts after age 10 years between at-risk males and females
The risk of developing type 1 diabetes (T1D) decreases in girls after age 10, while the risk in boys remains stable. Males with a single autoantibody have a significantly higher risk of T1D than their female counterparts.
When certain boys feel their masculinity is threatened, aggression ensues
A new study found that adolescent boys respond aggressively when they believe their masculinity is under threat, particularly in environments with rigid, stereotypical gender norms. The researchers suggest challenging restrictive norms and social pressure to prevent the development of 'fragile' masculinities.
Largest ever genetic study of age of puberty in girls shows links with weight gain
A large-scale genetic study has found a significant link between the age of puberty in girls and weight gain, highlighting potential risks for early puberty and obesity. The study identified over 1,000 genetic variants that influence the age of first menstrual period, with around 600 being observed for the first time.
What women want: Female experiences to manage pelvic pain
A new study from the University of South Australia explores female experiences with pelvic pain and identifies key concepts for effective pain management. The study found that women value learning about the biological explanation for persistent pain, which can help change outcomes and reduce stigma.
Earlier puberty onset may be one of the ways that childhood risk factors affect adult cardiometabolic health
A study published in PLOS ONE found that earlier puberty onset is associated with higher adult cardiometabolic risk and mediates the effects of childhood risk factors. The research suggests targeting puberty onset may improve health outcomes in at-risk girls.
Stress during pregnancy can lead to early maturation of first-born daughters
A 15-year longitudinal study by UCLA researchers identifies an association between prenatal stress and early signs of adrenal puberty in first-born daughters. This finding adds to the understanding of fetal programming and its impact on child development.
Skin-deep resilience: Hidden physical health costs for minority youth overcoming adversity
A new study from the University of Illinois finds that high-striving minority youth in early adolescence may experience accelerated puberty development, a potential indicator of 'skin-deep resilience,' which can lead to physiological changes such as inflammation and metabolic disorders.
Why does puberty trigger us to stop growing?
New research from University of Illinois Chicago identifies a potential 'stop growing' switch triggered by steroid hormone ecdysone in fruit flies, which may relate to human puberty. The study's findings have implications for understanding the growth-stopping process in humans, particularly given recent changes in puberty onset.
Developmental trajectory of body weight in youths at risk for major mood disorders
Weight gain in females with a family history of mood disorders begins before the onset of mood disorders, highlighting the need for childhood interventions. Early interventions can prevent adverse mental and physical outcomes in this vulnerable group.
University of Cincinnati research shows PFA exposure may delay girls’ puberty
A University of Cincinnati study found that exposure to PFAS may delay the onset of puberty in girls by an average of five or six months. The researchers also discovered decreased hormone levels consistent with the delay, raising concerns about negative long-term health outcomes such as breast cancer and renal disease.
Why are male kidneys more vulnerable to disease than female kidneys? USC Stem Cell-led mouse study points to testosterone
A USC Stem Cell-led mouse study reveals that lowering testosterone can improve the resilience of male kidneys by reducing their vulnerability to disease. The researchers also found that three months of calorie restriction has a similar effect, suggesting new potential treatments for kidney diseases.
Boys who smoke in their early teens risk passing on harmful epigenetic traits to future children
A new study reveals that boys who smoke in their early teens may damage the genes of their future children, leading to increased risks of developing asthma, obesity, and low lung function. Researchers investigated epigenetic profiles of 875 people aged 7-50 and found changes associated with fathers' teenage smoking.
More girls started puberty early during the COVID-19 pandemic
A new study found an increase in precocious puberty diagnoses among girls during the COVID-19 pandemic due to poor lifestyle changes. Girls with higher body mass index scores were more likely to be diagnosed with early puberty, suggesting a link between rapid weight gain and advanced pubertal development.
Age of those with mismatched biological sex and gender identity (gender dysphoria) is falling
The age of individuals with gender dysphoria has decreased, especially among those assigned female at birth, according to research published in General Psychiatry. The estimated prevalence of gender dysphoria rose significantly between 2017 and 2021, while the average age of diagnosis fell from 31 to 26.
Mouse study hints at specific brain receptor behind PCOS symptoms
A mouse study suggests that a specific brain receptor, the leptin receptor, may be involved in the development of PCOS symptoms. Researchers found that mice exposed to excess androgens prenatally had improved estrous cycles and regulation of their menstrual cycles, offering potential therapeutic targets for people with PCOS.
Youth overweight a risk factor for blood clots as adult
A University of Gothenburg study of over 37,000 men found that being overweight in childhood and young adulthood significantly increases the risk of venous blood clots later in life. The study also suggests that overweight in puberty has a marked impact on future risks of venous thrombi.
Reproductive factors in women contribute to risk of cardiovascular disease
A new study from Imperial College London finds that earlier first birth, higher number of live births, and starting periods at a younger age increase the risk of cardiovascular problems in women. The researchers hope their findings will help doctors better understand and monitor women's risk factors.
Gender dysphoria in young people is rising—and so is professional disagreement
The number of US minors receiving hormone treatment and surgeries has risen significantly, despite concerns over the lack of strong evidence. Experts are questioning the evidence underpinning guidelines from organizations such as WPATH and the Endocrine Society.
Oral contraceptives impact on women’s health: Age and gut microbiome may be determining factors
Research from the University of Ottawa finds that oral contraceptives' effects on brain and mood in women may be linked to age of onset and gut microbiome. The study suggests adolescence as a critical period for understanding OCs' impact, as it influences brain development and hormonal changes.
Vitamin D supplementation, development among school-age children in an area with vitamin D deficiency
A randomized clinical trial of 8,800 school-age children with high vitamin D deficiency showed no impact on growth or pubertal development after 3 years of weekly oral vitamin D administration. Vitamin D deficiency is associated with stunting and obesity in children.
Research suggests that children who doubt their gender identity enter puberty earlier
A new study from Aarhus University found that children expressing a desire to be the opposite gender at age 11 enter puberty around two months earlier than peers. This correlation highlights the importance of awareness among healthcare professionals about previous puberty development.
How is puberty onset developmentally programmed?
Research reveals TBX3 as a fate determinant controlling hypothalamic KNDy neuron development and puberty onset. Multiple TBX3 mutants fail to form phase-separated condensates, leading to delayed puberty in UMS patients.
Consequences of early life adversity on the brain
Research reveals early life adversity shapes brain circuits and behavior, increasing risk of depression and anxiety. Studies using rodent models uncover specific neural pathways impacted by early stress, shedding light on sex-specific responses.
$3.6 million grant backs effort to better treat Crohn’s disease
Researchers at UVA Children's will use a sophisticated computer model to better understand and treat Crohn's disease, which can have lifelong consequences for young patients. The team hopes to identify biological markers or metabolic signatures that can be used for early diagnosis and personalized medicine.
THE LANCET CHILD & ADOL. HEALTH: Study suggests discontinuation of gender-affirming hormones in those who start treatment as adolescents is rare
A study of over 700 adolescents who underwent puberty suppression and then started gender-affirming hormone treatment found that 98% continued use. The findings contradict recent concerns about regret and support the long-term benefits of hormone therapy for young people with gender dysphoria.
New avenues to reduce long-term complications in preterm infants
Researchers found that administering nitric oxide to preterm mice after birth can reverse symptoms of congenital hypogonadotropic hypogonadism, including sensory and cognitive disorders. A clinical trial is now underway to test this treatment in human preterm infants.
Transgender women’s heart-lung capacity and strength exceed those of cisgender peers even after years of hormone therapy
A study of 15 transgender women found they exceeded the cardiopulmonary capacity and muscle strength of their cisgender peers even after years of hormone therapy. However, their performance was lower than that of cisgender men. The findings could inform policy on transgender women's sports participation.
A study by the IMIBIC and UCO identifies a new mechanism involved in the reproductive function
A study by IMIBIC and UCO found that brain-regulated microRNAs influence reproductive capacity in males and females. The researchers discovered that microRNAs are crucial for Kiss1 neurons, essential for proper pubertal activation and adult reproduction.