Scientists have identified a molecular mechanism that leads overweight female rats to experience early-onset puberty. The study found that the SIRT1 enzyme plays a crucial role in transmitting body weight information to the brain, affecting the expression of the Kiss1 gene.
SourceOregon Health & Science University·JournalNature Communications·DateOct 10, 2018
Research suggests that weight gain between childhood and puberty increases the risk of developing asthma later in life, including for future generations. The study found no correlation between weight gain before or after puberty, but rather a link to overall inflammation during this critical developmental period.
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A new study found that eight- to nine-year-old children are vulnerable to poor body image as hormone levels rise with the onset of puberty. The research, led by Dr. Elizabeth Hughes, suggests that strategies in schools and at home can help maintain a positive body image prior to puberty.
SourceUniversity of Melbourne·JournalJournal of Adolescent Health·DateAug 14, 2018
A new study from Purdue University finds that early puberty in white adolescent boys is associated with a higher risk of substance use. Testosterone activity, rather than physical changes or social pressures, contributes to this increased risk.
SourcePurdue University·JournalChild Development·DateJul 16, 2018
A population-based study in Gothenburg, Sweden identifies BMI change during puberty as a potential novel risk factor for adult heart failure in men. Boys who were normal weight at 8 years of age and became overweight during puberty were three times more likely to be diagnosed with heart failure as adults.
SourceEuropean Association for the Study of Obesity·DateMay 23, 2018
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A Kaiser Permanente study of over 15,000 girls and their mothers found that maternal overweight and hyperglycemia are associated with earlier onset of puberty. The study suggests that the in utero environment may affect pubertal development, increasing the risk of adverse health outcomes.
SourceKaiser Permanente·JournalAmerican Journal of Epidemiology·DateApr 16, 2018
Researchers have discovered that changes in social behavior during adolescence are not triggered by pubertal hormones. Using Siberian hamsters as a model, the team found that behavioral shifts, such as play-fighting to social dominance, occur at the same time regardless of puberty timing.
SourceUniversity at Buffalo·JournalCurrent Biology·DateMar 19, 2018
A new study suggests that overeating during breastfeeding may lead to an increased risk of obesity, diabetes, advanced puberty, and reduced fertility in children. The research found that mice whose mothers were fed a high-fat diet during breastfeeding experienced obesity, early puberty, and reproductive problems in their offspring.
Research from Imperial College London found that girls who start puberty earlier are more likely to be overweight as adults. The study used genetic variants to investigate the causal link between early puberty and body mass index (BMI) in women, suggesting that early puberty itself is a risk factor for obesity.
SourceImperial College London·JournalInternational Journal of Obesity·DateMar 15, 2018
A study of nearly 8,000 girls found that those who began menstruating earlier were more prone to depression and antisocial behavior in their late 20s. This suggests that psychological problems can persist for years after adolescence, warranting continued awareness and support from pediatricians.
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers at UMass Amherst and University of Missouri found that prenatal exposure to a mixture of fracking chemicals affects mouse mammary gland development, leading to potential pre-cancerous lesions. Further studies are needed to evaluate the effects on long-term health and lactational capacity.
SourceUniversity of Massachusetts Amherst·JournalEndocrinology·DateFeb 7, 2018
Midlife women are disproportionately affected by asthma due to testosterone's impact on ILC2 proliferation and airway inflammation. The study highlights the importance of sex hormones in treating respiratory diseases.
SourceVanderbilt University Medical Center·JournalCell Reports·DateNov 28, 2017
A study found that genetic determinants of puberty timing are associated with lower bone mineral density in childhood and adulthood. Later puberty is linked to lower bone mineral density, especially in the lower spine, increasing the risk of osteoporosis and bone fractures.
SourceChildren's Hospital of Philadelphia·JournalJournal of Bone and Mineral Research·DateNov 27, 2017
A new study published in PLOS Biology found that sexual touch can contribute substantially to the acceleration of puberty in rats. The researchers observed that young female rats housed with male rats experienced an expansion of their genital cortex, a finding that was not seen in females housed with other females or males separated by...
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Research reveals that young women who start menstruating earlier may spend less time in education due to delayed emotional development. On average, starting menstruation one year later was associated with an additional 53 days spent in education.
SourceImperial College London·JournalBehavior Genetics·DateAug 9, 2017
A University of California, Berkeley study found that puberty hormones can reduce brain plasticity in young girls, potentially affecting their ability to learn and adapt. The study suggests that the early onset of puberty, driven by factors like stress and obesity, may have broad implications for girls' education and health.
SourceUniversity of California - Berkeley·JournalCurrent Biology·DateJun 1, 2017
Research found that progesterone levels are associated with fewer headaches in older teenagers and more headache in younger girls. Cyclic hormonal fluctuations during puberty may contribute to the differences in headache severity.
SourceUniversity of Cincinnati·JournalCephalalgia·DateMay 8, 2017
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A new analysis found that gender differences in depression symptoms and diagnoses emerge at age 12, with women disproportionately affected. Puberty and social changes may contribute to the onset of depression in girls during this age range.
SourceUniversity of Wisconsin-Madison·JournalPsychological Bulletin·DateApr 27, 2017
A new study published in Nature Genetics has identified 389 genetic signals linked to the timing of puberty, including associations with an increased risk of breast, ovary, and endometrial cancers in women, and prostate cancer in men. The research also suggests that earlier puberty timing may have negative effects on later health.
SourceUniversity of Cambridge·JournalNature Genetics·DateApr 24, 2017
Research suggests that exposure to common pesticides like pyrethroids may cause boys to reach sexual maturity earlier. A study of Chinese boys found a strong association between increased levels of the pesticide metabolite 3-PBA and accelerated puberty, including higher levels of testosterone.
New Penn State research reveals that childhood sexual abuse can accelerate physical growth and maturation in adolescents, increasing the risk of behavioral and mental health problems. The study found that young girls with a sexual abuse history were more likely to transition into higher puberty stages earlier than non-abused peers.
SourcePenn State·JournalJournal of Adolescent Health·DateMar 28, 2017
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Researchers analyzed data from over 4700 women to find a significant association between early puberty and later development of gestational diabetes. Women who started their periods before age 11 were 50% more likely to develop gestational diabetes.
SourceUniversity of Queensland·JournalAmerican Journal of Epidemiology·DateMar 5, 2017
Researchers found that DNA amount controls initial steroid hormone production, signaling start of metamorphosis. This internal timer determines juvenile development and makes metamorphosis irreversible.
SourceUniversity of California - Riverside·JournalPLOS Genetics·DateJan 26, 2017
A large international study has linked early puberty and childlessness to an increased risk of early menopause. Women who had their first period before age 11 were 80% more likely to experience premature or early menopause.
SourceUniversity of Queensland·JournalHuman Reproduction·DateJan 25, 2017
A recent study found that girls from low-income families in the US are unprepared for puberty, with many reporting negative experiences during this transition. The research highlights the need for more robust interventions to support and provide information about puberty for low-income girls.
SourceColumbia University's Mailman School of Public Health·JournalJournal of Adolescent Health·DateJan 4, 2017
Researchers found that providing free sanitary pads and puberty education to girls in Uganda improves their school attendance levels by 17%, compared to schools without such interventions. This simple yet effective approach can have major long-term economic implications for women's education and empowerment.
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A 12-year-long study found that teenage calorie expenditure drops by up to 500 fewer calories while at rest during puberty, contributing to excess weight gain and obesity. The research also revealed a significant decline in physical activity among teenagers during this period.
SourceUniversity of Exeter·JournalInternational Journal of Obesity·DateSep 8, 2016
A research team has discovered that male animals trigger female reproduction through their chemical signals, which also hasten females' aging process. The study found two distinct signals produced by males that affect female physiology, with one causing earlier puberty and the other slowing down aging.
SourceNorthwestern University·JournalCurrent Biology·DateSep 8, 2016
Activation of estrogen receptor alpha in brain region necessary for adult mice to express typical male social behaviors. Inhibition before puberty affects both sexual and aggressive behavior in adulthood.
SourceUniversity of Tsukuba·JournalProceedings of the National Academy of Sciences·DateJul 19, 2016
Danish researchers have discovered a possible connection between environmental factors and the onset of puberty. They found that epigenetic changes in the human genome are involved in defining pubertal timing, with specific DNA methylation patterns indicating whether a child has entered puberty.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalScientific Reports·DateJun 28, 2016
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A new study reveals that pubertal timing has a significant impact on male reproductive health, with early or late onset associated with poorer semen quality and smaller testicles. The study also found links between pubertal timing and obesity, cardiovascular disease, and sexually transmitted diseases.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalHuman Reproduction·DateJun 8, 2016
A Kaiser Permanente study found that girls whose mothers were overweight before pregnancy and had gestational diabetes are more likely to experience earlier pubic hair development. The study also suggests that metabolic programming may be affected in the daughters, manifesting in early onset of puberty.
SourceKaiser Permanente·JournalAmerican Journal of Epidemiology·DateJun 6, 2016
MicroRNAs play a crucial role in controlling fertility and puberty by regulating the expression of gonadoliberin or GnRH, a neurohormone that stimulates sexual maturation. Failure to produce microRNAs leads to infertility and sterility in adults.
SourceINSERM (Institut national de la santé et de la recherche médicale)·JournalNature Neuroscience·DateMay 2, 2016
Researchers found that female pelves widen with puberty, reaching full width by age 25-30, but then narrow again after menopause. Hormone levels drive this process, suggesting the body can modulate pelvic dimensions to ensure optimal childbirth.
SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateApr 25, 2016
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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A new study suggests that traditional ballet practices may be counterproductive for young dancers, particularly late-maturing girls. The researchers propose adopting a 'bio-banding' approach to training, grouping individuals by biological rather than chronological age, to better support their development and reduce injury risk.
SourceUniversity of Bath·JournalJournal of Adolescence·DateApr 4, 2016
Research suggests that combining aromatase inhibitors with growth hormone can effectively and safely increase height in very short adolescent boys. The study found significant gains in height and lean body mass when using this combination therapy.
Scientists uncover network of genes controlling puberty onset, discovering repressors that delay puberty. The study may help develop new treatments for precocious puberty and understand the impact of environmental factors on early puberty onset.
SourceOregon Health & Science University·JournalNature Communications·DateDec 16, 2015
A first-of-its-kind study of puberty timing in men reveals a strong genetic correlation with females, showing that the same genetic factors influence both sexes. The study found five new genetic variants associated with puberty timing, some acting through known hormone pathways.
SourceEdelman, Orlando·JournalNature Communications·DateNov 9, 2015
Research published in Heliyon found that women born in summer months were more likely to be healthy adults, with slightly higher birth weights and later onset of puberty. This effect is thought to be linked to increased vitamin D exposure during pregnancy, which can influence childhood growth and development.
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A new study found that taking a gadget to bed can suppress melatonin production and disrupt sleep patterns in children aged 9-15, especially those in early puberty. The study also found that brighter screen lights have a greater impact on sleep, with 500 lux being the most effective at suppressing melatonin.
SourceBrown University·JournalThe Journal of Clinical Endocrinology & Metabolism·DateAug 26, 2015
A study by the National Institutes of Health found that low-level arsenic exposure before birth is associated with early puberty and obesity in female mice. The researchers exposed pregnant mice to low levels of arsenic through drinking water and observed significant weight gain and premature onset of puberty in the offspring.
SourceNIH/National Institute of Environmental Health Sciences·JournalEnvironmental Health Perspectives·DateAug 26, 2015
A young woman has become the first to give birth naturally after doctors transplanted frozen ovarian tissue from her removed at age 13. The procedure restored her fertility and allowed her to conceive without assisted reproduction.
SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·DateJun 9, 2015
Researchers discovered a genetic fault preventing SEMA3E from working correctly in two brothers with Kallman Syndrome, leading to the loss of nerve cells regulating sexual reproduction. The study demonstrates a powerful method for identifying genetic causes without relying on large statistical samples.
SourceUniversity College London·JournalJournal of Clinical Investigation·DateMay 18, 2015
A study found that young children's aversion to opposite-sex peers (the 'cooties' effect) is encoded in the amygdala. As children enter puberty, interest in opposite-sex peers blooms anew, with some becoming infatuated with a member of the opposite sex.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalJournal of Cognitive Neuroscience·DateApr 9, 2015
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A unique genetic disorder responsible for ovarian insufficiency has been discovered by Tel Aviv University researchers. The SYCE1 gene mutation was found to be the underlying cause of primary ovarian insufficiency in two sisters, and its effects were also detected in three brothers and parents.
SourceAmerican Friends of Tel Aviv University·JournalThe Journal of Clinical Endocrinology & Metabolism·DateDec 17, 2014
A new study by University of Illinois psychologist Karen D. Rudolph found that early puberty triggers psychological, social-behavioral and interpersonal difficulties that predict elevated levels of depression in both boys and girls. Early maturation was particularly detrimental to girls, who experience immediate psychological and envir...
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalDevelopment and Psychopathology·DateNov 19, 2014
Repeat testing after puberty revealed abnormal electrocardiogram findings in most individuals with a first-degree relative with Brugada syndrome. This suggests the need for repeated monitoring of family members of patients with Brugada syndrome, even those initially considered at low risk due to young age.
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GnRH neurons in rat preoptic area undergo morphological changes during puberty, including inverted Y distribution pattern and increased spine-like processes. These findings provide insight into reproductive maturation and GnRH regulation.
SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateAug 12, 2014
A new study reveals a significant link between childhood obesity and an earlier age of puberty, with heavier children at age five tending to have lower SHBG levels and reach puberty sooner. The findings suggest that obesity in childhood may contribute to the decline in the age of puberty over the past century.
SourceUniversity of Plymouth·JournalThe Journal of Clinical Endocrinology & Metabolism·DateJul 27, 2014
Researchers found that imprinted genes influence puberty timing, linking it to breast cancer, diabetes, and heart disease risks. The study suggests a possible biological conflict between parents over their child's development, with the genetics involved potentially contributing to age-related conditions.
SourceHebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research·JournalNature·DateJul 24, 2014
A study of over 180,000 women found that imprinted genes, active only when inherited from one parent, influence the age of puberty in girls. These genetic variations were associated with a difference in development between boys and girls.
SourceBoston University School of Medicine·JournalNature·DateJul 23, 2014
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A new study found that genetic variations, particularly imprinted genes, play a significant role in determining the age of puberty in girls. The research analyzed DNA data from over 180,000 women and identified six imprinted gene variants associated with earlier or later menstrual cycles.
SourceUniversity of Cambridge·JournalNature·DateJul 23, 2014
A new study finds that the brain of children with gender dysphoria reacts to androstadienone, a male musk-like steroid, in a way typical of their biological sex at puberty, but shifts to their experienced gender afterwards. This suggests a partial rewiring of the brain as children grow up.
SourceFrontiers·JournalFrontiers in Endocrinology·DateMay 28, 2014
Researchers found that cerebral blood flow levels decreased before puberty but diverged sharply after, with females experiencing increased flow and males decreasing further. This divergence may contribute to sex-specific differences in behavior and risk for psychiatric disorders.
SourceUniversity of Pennsylvania School of Medicine·JournalProceedings of the National Academy of Sciences·DateMay 26, 2014
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Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Research from the Children of the 90s study at the University of Bristol found that men who started smoking before age 11 had sons with significantly higher body fat content compared to those who started smoking later. This study suggests a potential transgenerational effect of tobacco exposure on metabolic changes in the next generation.
SourceUniversity of Bristol·JournalEuropean Journal of Human Genetics·DateApr 2, 2014
A University of Iowa study found that men's noses are about 10 percent larger than female noses, on average, in populations of European descent. The size difference is attributed to the sexes' different builds and energy demands.
SourceUniversity of Iowa·JournalAmerican Journal of Physical Anthropology·DateNov 18, 2013
Exposure to ionizing radiation during puberty increases the risk of developing aggressive ER negative breast cancers later in life. Researchers discovered that self-renewal of stem cells is the primary mechanism behind this increased risk.
SourceDOE/Lawrence Berkeley National Laboratory·JournalStem Cell Research·DateSep 11, 2013
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers found that vitamin D deficiency is linked to early onset of puberty in girls, with 44% having severe deficiencies. Vitamin D supplementation may help delay pubertal onset and progression.
A new study presented at The Endocrine Society's Annual Meeting found that hormone treatment to halt puberty in transgender adolescents is effective and safe, relieving psychological suffering. After cross-sex hormone therapy, bone density caught up, similar to natural puberty, with no long-term harm detected.
Researchers identified a genetic mutation in the MKRN3 gene that leads to premature puberty. The mutation is inherited from the father and disrupts protein function, triggering early reproductive hormone activation.
SourceBrigham and Women's Hospital·JournalNew England Journal of Medicine·DateJun 5, 2013
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