The new centers aim to better understand the interplay between environmental science, climate change, and human health in oceans and Great Lakes. Researchers will study microplastics, algal blooms, and their impact on seafood safety and human health.
Researchers found that AI/ML based programs can successfully detect PCOS with an accuracy of 80-90%, making it a promising tool for early diagnosis and reducing the burden on patients. The study suggests integrating large population-based studies with electronic health datasets to identify sensitive diagnostic biomarkers.
Researchers found a significant association between high particulate matter exposure and an 8% increase in breast cancer incidence among US women. The study, which considered historical air quality data, suggests that fine particulate matter may affect breast cancer through endocrine disruption.
A new study by researchers at the National Institutes of Health found that women diagnosed and treated for breast cancer have increased biological aging compared to those who remain free of breast cancer. Radiation therapy showed the strongest association with faster biological aging, while surgery had no effect.
The National Institutes of Health recognizes World Asthma Day and highlights innovative research on asthma, its causes and treatments. Several NIH institutes conduct and support asthma-related research, including NIEHS, NHLBI, and NIAID.
Researchers at the National Institutes of Health have discovered a possible cause for rare genetic disorders, facioscapulohumeral muscular dystrophy (FSHD) and arhinia. The toxic protein DUX4, overproduced in FSHD patients, not only kills muscle cells but also prevents the development of the human nose.
Researchers developed a 3D organoid model that mimics human heart development, revealing how low levels of cadmium can block cardiomyocyte formation and induce heart abnormalities. The study supports decades of toxicology research on environmental exposures contributing to human diseases.
A new NIH study found that frequent use of hair straightening products was associated with a higher risk of uterine cancer, particularly among Black women. The researchers estimated that women who used these products frequently were more than twice as likely to develop uterine cancer compared to those who did not use them.
Researchers found that oil spill cleanup workers were 60% more likely to be diagnosed with asthma or experience asthma symptoms one to three years after the spill. The study linked specific chemicals, including BTEX-H, to increased asthma risk.
Researchers at NIH have developed a 3D structure of the twinkle protein, which helps identify mutations that cause mitochondrial diseases. The discovery could lead to targeted treatments for patients with conditions like progressive external ophthalmoplegia and Perrault syndrome.
Researchers found that women with higher concentrations of phthalate metabolites in their urine were more likely to deliver babies preterm. The largest study to date on this topic found that reducing phthalate exposure by 50% could prevent preterm births by 12% on average.
Researchers at NIH have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia. By boosting macrophage eating capacity using EETs inhibitors, they reduced bacteria numbers in lung tissue and improved treatment outcomes.
Scientists found that male sex hormones prevent stomach inflammation by suppressing immune cells, while females lack this protection. The study suggests treating males with stomach inflammation differently than females.
A new study found that unbalanced progesterone signals may cause preterm labor or prolonged labor in pregnant women. The researchers used genetically engineered mouse models to alter the ratio of PGR-A and PGR-B signaling in the uterus, identifying key biological pathways influenced by both forms.
The mosquito protein AEG12 destabilizes the viral envelope, breaking its protective covering. The findings could lead to therapeutics against viruses affecting millions of people worldwide.
Researchers found that inhaling unfragmented hyaluronan improves lung function in patients with severe COPD, shortening hospital stays and decreasing breathing support needs. The treatment also aids mucus transport and promotes recovery.
The study found significant increases in antinuclear antibody prevalence in the US population, particularly among males and adolescents. The researchers suggest changes in lifestyle or environment may be involved in these increases.
The National Institute of Environmental Health Sciences (NIEHS) is launching a new COVID-19 worker training program to protect frontline responders' health. The program aims to provide virtual safety training and resources to employees at high risk of exposure, with the goal of preventing illness and reducing transmission.
Traffic-related air pollution has been linked to an increased risk of hypertensive disorders in pregnant women, with exposure to particulate matter (PM2.5) associated with a 50% higher likelihood of developing preeclampsia. The study highlights the need for further research into the impact of environmental exposures during pregnancy.
A study published by NIH found that frequent use of permanent hair dye and chemical straighteners increases breast cancer risk, especially among African American women. Women who regularly used permanent dyes were 9% more likely to develop breast cancer than those who didn't use hair dye.
A new graphene-based film has shown promise in blocking mosquito bites by interfering with their ability to sense skin and sweat. The dry film provides a strong mechanical barrier that prevents mosquitoes from landing and biting.
A new study published in the Journal of the American Medical Association found a strong link between long-term exposure to air pollution and an increased risk of emphysema in the US population. The study analyzed data from over 7,000 participants and found that consistent results were found across six metropolitan regions.
Research finds that cutting off lights at bedtime could reduce women's chances of becoming obese. The study analyzed data from 43,722 women and found a link between artificial light exposure and increased weight gain.
Two proteins, glucocorticoid receptor and mineralocorticoid receptor, work together to support heart health in mice. The study's findings may lead to the development of therapeutic compounds that help people with an increased risk of a heart attack by regulating cortisol levels.
A recent study found that vitamin D levels can modify the response to indoor air pollution in obese urban children with asthma. The research team identified a significant link between low blood vitamin D levels and respiratory problems, as well as an inverse relationship between high blood vitamin D levels and asthma symptoms.
Researchers used DNA methylation to estimate biologic age and found that women with older biologic ages had higher breast cancer risks. The study suggests that biologic age may be tied to environmental exposures, potentially serving as an indicator of disease risk.
Women who have given birth experience a lower risk of breast cancer, but this protective effect may not begin until as many as 30 years after the last pregnancy. A new study found that breast cancer risk increases in the years following childbirth, with the highest risk about five years later.
New research suggests that infant girls fed soy formula are more likely to develop severe menstrual pain as young adults. Women who had ever been fed soy formula as babies were 50% more likely to have experienced moderate or severe menstrual discomfort between the ages of 18 and 22.
Asthma patients with specific genetic profiles exhibit more intense symptoms following traffic pollution exposure. The study suggests that tailoring treatments to individual gene-environment interactions could enhance quality of life for people with asthma.
A large international study found that high body fat in young women reduces breast cancer risk before menopause. Researchers discovered a 12-23% decrease in breast cancer risk for every five-unit increase in BMI, with strongest effects seen in the 18-24 age group.
Researchers have developed a new technique called spectrally resolved fiber photometry (SRFP) that can measure the activity of two distinct neuron groups in the mouse brain. This method allows for the simultaneous measurement of neural activity in both healthy and diseased brains, shedding light on neurological disorders such as Parkin...
Studies found tumors in tissues surrounding nerves in male rat hearts at high radiofrequency radiation levels, but not female rats or mice. Researchers also noted damage to heart tissue and increased cancer risk in exposed animals.
A new method developed by NIH researchers uses a novel approach to categorize and visualize career outcomes of postdoctoral fellows, revealing distinct differences between US and international postdocs. The study found that nearly half of NIEHS postdocs went into the academic sector, contrary to common assumptions.
A new study by NIH researchers found a molecular basis for the theory of aging, suggesting that environmental stressors can shorten lifespan. The study identified a protein called Mthl10, which helps flies defend against inflammation but ultimately shortens their life.
The study found that 90% of US homes have at least one elevated allergen level, with pets and pests playing a major role. Housing characteristics and geographic locations also impact allergen exposure levels. Preventive actions can help reduce exposure to indoor allergens.
Researchers found that a protein named ZATT can eliminate DPCs with the help of another protein TDP2. Understanding how TDP2 and ZATT work together may improve cancer patient health outcomes. The discovery could lead to development of new drugs targeting these defenses.
A study by the National Institutes of Health found that Gulf spill cleanup workers who handled oil dispersants or were exposed to them during cleanup reported symptoms such as cough, wheeze, and skin and eye irritation. The study suggests a short-term effect of dispersants on health symptoms.
Researchers at NIH reveal that COUP-TFII determines sex-specific reproductive system development in mice. Female mouse embryos without COUP-TFII display both male and female ducts, indicating the active removal of male reproductive systems.
Researchers found higher levels of lead and lower levels of zinc and manganese in children with autism compared to those without. The study used lasers to map growth rings in baby teeth to track metal uptake during development.
The National Institutes of Health is finding solutions to improve the health of nearly 25 million Americans with asthma. Research funded by NIEHS, NHLBI, and NIAID has demonstrated the importance of healthy school environments and explored the complex role of the immune system in asthma.
A new research from the National Institutes of Health found that pairing antidepressant amitriptyline with central nervous system drugs enhances drug delivery to the brain. Amitriptyline temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain.
The 14th Report on Carcinogens adds seven new substances to the list, including five viruses that have been linked to cancer in humans. Trichloroethylene, cobalt compounds, HIV-1, HTLV-1, EBV, KSHV, and MCV are among the newly listed substances, highlighting the importance of prevention strategies to reduce the world's cancer burden.
A NIH/National Institute of Environmental Health Sciences study found that dust mite allergens are more stable and abundant than other dust mite proteins. This discovery may lead to the development of new approaches for treating dust mite allergies, a common trigger for asthma.
The National Institute of Environmental Health Sciences has launched a three-year, $9 million training program to educate approximately 35,000 first responders and hazardous waste workers on infectious disease safety. The program aims to minimize the spread of disease to others while protecting these workers from exposure.
The NIH has partnered with EPA to fund five new research centers studying environmental health disparities, including air and water pollution, housing conditions, and diet. The centers will work with community organizations to develop culturally appropriate strategies to reduce exposure to harmful environmental conditions.
A study of 108,630 women found that living near areas with high levels of green vegetation was associated with lower mortality rates, particularly from kidney disease, respiratory disease, and cancer. The researchers attributed this to improved mental health, social engagement, physical activity, and reduced air pollution.
Five exceptional early career scientists will receive new grants from NIEHS to study the effects of environmental chemicals on human health. The ONES awardees will investigate how pollutants, such as arsenic and dioxins, cause harm and promote allergies.
Researchers at NIH/NIEHS discovered that increasing tristetraprolin (TTP) levels in mice significantly reduced or protected against inflammation. TTP may offer an effective treatment for inflammatory diseases such as rheumatoid arthritis, psoriasis, and multiple sclerosis.
Research suggests that eating at least one seafood serving per week may lower the risk of developing Alzheimer's disease in older adults with the APOE-4 gene. The study found no association between seafood consumption and increased brain mercury levels or beta amyloid protein plaques, key markers of the disease.
The study found that households using the test kits had a consistent reduction in dust mite allergens over the course of the 12-month study period. A significant number of parents reported adopting behaviors to reduce dust mites after seeing their test kit results, such as using special pillow covers and vacuuming with HEPA filters.