A research group has identified a genetic mechanism called CHLORAD that regulates tomato ripening by promoting carotenoid production and altering chloroplast transformation. Activated CHLORAD systems produce tomatoes with more lycopene, leading to higher nutritional quality and attractive color.
Preliminary research suggests that taking more daily steps can lead to a longer life, even if it's done in short spurts or as part of regular activities. The study found that women who took 2,000 additional steps per day during bouts had further benefits for longevity.
A new cognitive construct called 'decision acuity' was identified as a stable factor underlying diverse decision-making abilities in adolescents and young adults. Decision acuity was linked to factors such as fast learning, reward sensitivity, and low propensity for retaliation, and predicted performance in decision-making tasks.
A new study found that the 2016 US presidential election may have triggered potentially life-threatening heart rhythms and worsened high blood pressure in people with underlying cardiovascular disease. Researchers linked data from cardiac devices to find a significant increase in arrhythmias during the election period.
A new mechanism of condensation has been discovered in self-propelled particles, where they turn and move toward dense regions to accumulate. This finding challenges the traditional understanding of condensation, which relies on attractive forces between molecules.
The new device measures cardiac micropotential energies in real-time, allowing early detection of abnormal heart function. It has shown sensitivity and potential to prevent sudden cardiac death, with successful tracking of a volunteer's heart function over four years.
Researchers have identified a new canine-like coronavirus found in Malaysian pneumonia cases, indicating potential for animal-to-human transmission. The discovery highlights the need for better surveillance to detect novel coronaviruses and mitigate public health threats.
Experts recommend a mandatory UK register of doctors' financial and non-pecuniary interests. The proposed register aims to increase transparency for patients and reduce potential conflicts of interest, following concerns raised by the Cumberlege review.
A new study suggests that DJ-1 protein, which protects against free radicals inside cells, worsens inflammation outside the cell, leading to exacerbated pathologies in ischemic stroke. The researchers identified DJ-1 as a previously unknown inflammatogenic DAMP that may be a potential target for therapeutic intervention.
A brain-computer interface that mimics tactile sensation has significantly improved robotic arm control for a person with tetraplegia, performing tasks comparable to able-bodied humans. The new system, which reads and writes neural activity, reduces trial times by half compared to previous versions.
The co-planar optoelectrowetting device allows for individualized and parallel droplet actuation, increasing microfluidic input/output system integration configurations while achieving faster droplet speeds. The open-top design enables easier access to droplets from above, improving the performance of the device.
Researchers have developed a new, pixel-sized light detector that can accurately amplify weak signals in real-time, giving autonomous vehicles a fuller picture of their surroundings. This breakthrough increases sensitivity and consistency, making it ideal for lidar receivers and applications in robotics, surveillance, and terrain mapping.
Researchers have successfully grown sesame-seed-sized heart models using human pluripotent stem cells, which spontaneously self-organize into a hollow chamber without experimental scaffolds. The cardioids' wall-like tissue contracts rhythmically to squeeze liquid around the inside cavity, mimicking natural development.
A new iron-nitrogen-doped carbon catalyst has been developed to preferentially reduce nitric oxide to hydroxylamine, reducing harmful air pollutants. The catalyst achieved efficient (71%) NH2OH production in a prototypical NO-H2 fuel cell and exhibited long-term stability.
Researchers at the University of Plymouth developed a cutting-edge technique to measure energy use in developing embryos using timelapse video pixels. The method captures detailed changes in energy usage as an energy signature, providing a greater breadth of biological response.
A new study projects that climate change will exacerbate global food and hunger challenges, leading to increased mortality and disability. Researchers suggest that investing in agricultural R&D, irrigation systems, and market access could help mitigate these impacts.
A review of virtual reality training programs found that they can elicit empathetic behavior in medical radiation technologists, improving patient-centered care. The study suggests VR may be an effective tool for learning care recipients' perspectives and controlling biases in future research.
Researchers at the SETI Institute have detected rare meteor showers caused by 4000-year-old comets. The Cameras for Allsky Meteor Surveillance project uses low-light video security cameras to measure meteors' trajectories and orbits, revealing nine parent bodies of previously unknown meteor showers.
Research from Harvard University suggests that solar geoengineering may be surprisingly effective in alleviating some of the worst impacts of global warming on crops. The study found that all three potential methods have a strong cooling effect benefiting crop yields.
Research team from Shaanxi Normal University investigates the effect of alkaline metal cations on electrocatalytic CO2 reduction reaction using Fe porphyrins. The results show that adding Na+ and K+ ions significantly improves catalytic activity, with K+ enhancing currents more effectively.
Researchers achieved stable partial energy detachment and suppressed material sputtering using Ar and Ne seeding. The study provides a feasible experiment program for maintaining steady-state plasma under high-power long-pulse conditions.
A recent study presented at the American Heart Association's conference found that black adults who consumed ultra-processed foods were at a 55% increased risk for high blood pressure compared to white adults. The study analyzed data from over 6,000 participants and used the NOVA system to categorize food processing levels.
A study found that violent crime rates in urban Black and Hispanic communities are associated with higher rates of physical inactivity and obesity among adults. The analysis, which examined 2018 data from Chicago's police records and CDC data, suggests that exposure to violence may be a contributing factor to these health disparities.
Researchers at Duke University Medical Center discovered a new type of anti-glycan antibody that can neutralize HIV by targeting its sugar coating. This breakthrough points to a novel vaccine strategy that could also be used against SARS-CoV-2 and fungal pathogens.
A large-scale research project assessed Earth's 92,033 debris-covered glaciers and found that debris substantially reduces glacier mass loss. This discovery will improve risk assessment for communities near these glaciers, which can lead to glacial lake formation and potential flood hazards.
Researchers at Ruhr-University Bochum have discovered a universal functional mechanism of channelrhodopsins, which determines their efficiency as an optogenetic tool. This finding will help tailor more efficient optogenetic tools in the future by blocking inefficient pathways.
Adaptimmune Therapeutics plc reports initial data from its Phase 2 SPEARHEAD-1 trial showing a high response rate of 41.4% for patients with synovial sarcoma, including two complete responses and encouraging initial safety and durability. The trial's results support the company's BLA submission next year.
A new study from the University of Eastern Finland found that people with Alzheimer's disease are less likely to undergo cataract surgery compared to those without the condition. This decrease in procedure rate starts one year after diagnosis, highlighting a concerning trend that may impact patients' quality of life.
Researchers have demonstrated that HERV activation can impair brain development, leading to altered cortical neuron function and structure. This finding has important clinical implications, particularly in the context of neurodegenerative diseases.
The GEM ExTra test uses whole exome sequencing and RNA sequencing to detect actionable mutations in patients with advanced solid tumors. It has been validated through clinical utilization and provides clinically actionable information to guide patient management decisions.
The special issue explores various aspects of risk sciences and resilience analytics to guide decision-making and operations related to the COVID-19 pandemic. Papers cover topics such as risk perception, human health and infection risk, and risk management strategies.
Researchers at the University of Pittsburgh developed a brain-computer interface that uses brain stimulation to evoke tactile sensations, improving control of a robotic arm. The study found that supplementing vision with artificial tactile perception cut the time spent grasping and transferring objects in half.
Researchers developed cardioids, human self-organizing cardiac organoids that recapitulate heart chamber formation and function. The model reveals how signaling and transcription factors control cardioid chamber formation and triggers an in vivo-like accumulation of extracellular matrix proteins after injury.
Women who experience early menopause before age 40 have a 40% increased risk of developing coronary heart disease over their lifetime. The study suggests that clinicians should ask women about their menopause status earlier to optimize cardiovascular health and prevent heart disease.
Women with a history of weight cycling experience shorter sleep duration, poorer sleep quality, and increased risk of insomnia. The study also found that weight cycling is associated with an increased risk of obstructive sleep apnea, a serious health problem linked to heart disease and stroke.
Researchers at NUS have developed a method to increase the rate of ethylene hydrogenation by more than five times compared to typical industrial rates using oscillating electric potentials on commercial catalysts.
Researchers propose a new atavistic model of cancer, suggesting that ancient genes and reversions to ancestral forms are responsible for cancer's ability to survive and proliferate. The Serial Atavism Model challenges the conventional standard model of cancer, offering a novel perspective on the disease.
A new study developed by researchers at the University of Texas at Austin provides a method for public health planning authorities to calculate the number of COVID-19 isolation beds needed for people experiencing homelessness. The study helps cities ensure they have sufficient resources to protect populations in future disease outbreaks.
Researchers found that a significant gap between numerical age and biological age, as predicted by AI-enabled EKGs, is associated with increased risk of death from heart disease. The study validated the use of AI-aged EKGs in predicting mortality rates.
A new study finds that adding a small molecule can rip away the cloak shielding HIV-infected immune system cells, making them susceptible to patient's own antibodies. Researchers hope this breakthrough may one day eliminate the need for long-term antiretroviral treatments.
The Terasaki Institute has been awarded a grant by the Good Food Institute to develop an innovative method for producing cultivated meat. The project aims to address scalability and cost challenges in alternative protein production, using unique microcarriers to differentiate cell cultures.
The Cleveland Museum of Natural History has developed a new planetarium software plug-in that enables users to teach beyond the stars by exploring biodiversity trends and patterns. The tool allows educators to leverage 1.6 billion specimen records, creating customized programs on biodiversity and conservation.
A study found that exposure to the 2016 US presidential election was associated with an increase in potentially life-threatening cardiac events. The research, conducted in North Carolina, showed a 77% rise in the risk of arrhythmias during the election period compared to control periods.
Researchers at the University of Illinois have made significant breakthroughs in solid-state battery technology by controlling atomic alignment of materials to improve cathode-solid electrolyte interface stability. This enables more efficient charging and discharging cycles, leading to increased energy density and improved cycle life.
Research by MSU's Morteza Mahmoudi suggests that Covid-19 vaccines developed with nanomedicine may have different efficacies for men and women due to sex-based differences. The study highlights the importance of considering sex in vaccine development and research, particularly in using nanomedicines.
A team from Alfred Wegener Institute discovered that treeless areas have more species than mountain forests due to climate change. The study's findings suggest that broader habitats lead to a wider range of settings for diverse flora and fauna.
A new diet that restricts methionine has shown promising results in improving biomarkers of metabolic health, potentially slowing the aging process. The palatable oxidized casein diet could be a solution to offset major components of metabolic disease.
Researchers investigated anesthetics' influence on neonatal rat brains, using optical intrinsic signal imaging and non-invasive monitoring. Urethane was found to alter cortical rhythms dose-dependently, while isoflurane showed limited effects.
Researchers sequenced the entire genome from Peştera Muierii 1, a woman who lived in Romania 35,000 years ago. The study found high genetic diversity, suggesting that the greatest loss of genetic diversity occurred during the last Ice Age, rather than during the out of Africa migration.
A new study reveals key details of how SARS-CoV-2 variants escape the immune response created by natural infection or vaccination. The research highlights that several mutations are clustered in one site on the spike protein, disrupting antibody binding and neutralization.
Researchers at Universitat Autonoma de Barcelona discover dynamic changes in genome organisation affect male germ cell development and fertility. Chromosomal rearrangements alter chromosome folding, impacting meiotic recombination and genetic diversity.
A study by University of Houston researchers found that heart-focused anxiety is a significant predictor of depression and overall anxiety among Latinx young adults with previous trauma. This population often somaticizes mental health problems, making treatment more challenging.
A new class of molecules has been engineered to provide energy storage for aqueous organic redox flow batteries. The approach delivers a high energy efficiency even after four months of cycling at elevated temperatures.
Researchers developed an AI-based tool called SCMER to identify rare groups of biologically important cells from single-cell datasets. The tool was applied to analyze several published datasets, revealing new genes and proteins involved in tumor development and drug resistance.
A Chinese study found a strong association between exposure to secondhand smoke and ADHD symptoms in school-age children. The researchers assessed prenatal, early postnatal or current exposure and symptoms of attention-deficit/hyperactivity disorder (ADHD) among 1,044 children.
A new study led by UT Southwestern scientists shows that an experimental drug, avasopasem manganese (AVA), enhances radiation's capacity to kill tumors while protecting healthy tissue from collateral damage. The findings could provide a much-needed boost to radiation treatments used against various tumor types.
Researchers developed two experimental drug approaches targeting cancer cell metabolism, showing promise in treating highly aggressive pediatric brain cancer. The treatments extended survival and enhanced effectiveness of standard chemotherapies in patients with MYC-amplified medulloblastoma.
A new study analyzed over 800 coronavirus genetic samples to trace the path of the virus as it traveled across New York City during its deadly first wave. The research identified Queens and Brooklyn as major hubs of COVID-19 spread, with Queens playing a more significant role in viral transmission.
A Rensselaer-developed deep learning algorithm can identify patients at risk of cardiovascular disease using low-dose CT scans used for lung cancer screening, potentially expediting diagnoses and accelerating treatments.
A new single-cell analysis tool identifies a unique sub-population of macrophages in kidney tumors associated with disease recurrence. The tool, called meta-VIPER, builds on previous techniques to accurately detect gene activity in individual cells, revealing potential targets for treatment and improving clinical outcomes.