Researchers have developed a method to predict interactions among multiple drugs in combination, bypassing the need for astronomical measurements. The new mathematical model enables scientists to identify optimal blends for chemotherapy cocktails and potentially aid personalized medicine.
Researchers used gene expression analysis to map the functions of liver cells, revealing nine distinct types each specializing in its own tasks. This discovery may help clarify common liver disorders and provide insights into human health.
Weizmann Institute scientists have successfully erased fear memories in mice by disrupting the communication between two brain regions. The study, published in Nature Neuroscience, may one day lead to novel therapies for post-traumatic stress disorder (PTSD) and other anxiety disorders.
Researchers discovered that massive stars can exhibit instability for several months before a supernova explosion, creating a dense gas shell around themselves. This insight came from analyzing data collected by the Palomar Transient Factory telescope network.
Researchers suggest ancient ocean had green rusty mineral, green rust, which could have delivered substantial proportion of iron to early ocean sediments. Green rust forms under low oxygen conditions and can transform into iron oxides over time.
Researchers have identified ancient fava beans in Northern Israel, dating back 14,000 years, to understand the evolution of the crop and improve its biodiversity. The findings provide crucial clues about the time and place where wild faba plants grew naturally.
By controlling electron spin, scientists have almost fully suppressed hydrogen peroxide formation during water splitting, paving the way for efficient solar-based hydrogen production. This breakthrough could lead to more stable and efficient photoelectrochemical cells, increasing the feasibility of using solar energy to split water.
A study of an online stroke forum found that three in 10 stroke survivors will experience further strokes, highlighting the importance of secondary prevention medications. Despite this, patients often disregard general practitioners' advice on these medications, with some stopping treatment completely due to side effects.
Researchers developed a model suggesting early oceans were acidic, with pH between 6.0 and 7.5, conducive to primitive life's existence. Higher CO2 levels controlled ocean acidity, influencing chemical weathering and ion fluxes.
A prospective observational study found a high association between grey hair and coronary artery disease in adult men. Researchers discovered that as age increases, so does the incidence of both atherosclerosis and hair greying due to similar biological pathways.
The study found a consistent association between overweight and obesity with sickness absence, regardless of metabolic health status. Obese workers were 37% more likely to take sick leave for non-work-related illnesses than their healthy-weight colleagues.
A two-week high-intensity interval training (HIIT) program improved glucose metabolism in muscles of people with type 2 diabetes. HIIT surpassed traditional moderate intensity continuous training in its benefits, with significant improvements in insulin sensitivity and endurance noted.
A $4.6-million grant will investigate how students and teachers implement principles from the science of learning in educational settings. The project aims to provide students with tools to learn effectively on their own, regardless of career path.
Liza Grandia, a UC Davis associate professor of Native American studies, has received a $270,000 Mellon Foundation Fellowship to research toxicology and environmental epidemiology. Her project, 'Toxic Trespass,' aims to build cross-disciplinary bridges between indigenous communities and environmental health sciences.
Claude-André Faucher-Giguère, a Northwestern University astrophysicist, has received a Faculty Early Career Development Program award from the National Science Foundation. The $794,304 grant will support improved galaxy formation simulations and interactive visualizations for public outreach.
A new study finds that tropical lowland frogs are more vulnerable to climate change due to their limited ability to tolerate high temperatures. In contrast, high-elevation species may be better buffered against temperature increases.
NYU Assistant Professor Miguel Modestino has developed a method to create nylon-like textiles while capturing carbon dioxide from the environment. The process uses photovoltaic arrays, water, and plant waste to produce hexanediamine, one of the precursors to nylon.
Scientists have discovered that specific cells in the brain's medial amygdala program innate reproductive and aggressive behaviors. The study found that male and female brains respond differently to mating cues, with distinct patterns of activation in neurons expressing different transcription factors.
A team of scientists has discovered a rare sample of the mineral majorite, which originated at least 235 miles below Earth's surface. The discovery provides valuable insights into the dynamic processes occurring deep inside the Earth and its history, including the formation of mountain ranges that persist today.
A special issue of Annals highlights the potential of pulses to address global nutrition issues and environmental concerns through increased consumption. The report emphasizes the need for multi-sectoral partnerships, research, and public interventions to promote pulse consumption and yield improvements.
Jiri Friml, a plant biologist at IST Austria, has received an ERC advanced grant to investigate the evolution of auxin transport and polarity in plants. His research will focus on understanding how plants adapt to environmental changes through the dynamic regulation of PIN transporters.
Omalizumab, an asthma drug, demonstrates significant symptom improvements and prevention in patients with cold urticaria and symptomatic dermographism. The treatment was found to be effective in nearly half of patients with symptoms after exposure to stimuli.
Researchers have discovered a key peptide called DBI that promotes the production of new neurons in the hippocampus, a region critical for learning and memory. DBI binds to GABA receptors, suppressing its inhibitory effect and allowing neural stem cells to proliferate.
Researchers found that people who saw 'the dress' in a shadow perceived it as gold and white, while those under artificial light saw it as black and blue. Lifestyle factors such as sleep schedule also influenced color perception.
The American Gastroenterological Association recommends a tailored approach to PPI use for different conditions, weighing benefits against risks. Long-term PPI users should have their doses reevaluated regularly to minimize side effects.
A UTSA student-led team has received a $50,000 NSF grant to continue developing their infrared medical camera, InfraVein. The team will travel to Boston for the NSF I-Corps seminar series, where they will test their business model and market strategy with potential customers.
A Boston College study links income inequality to rising carbon emissions at the state level, with top 10% of population driving growth. States like California and Texas experience significant increases in emissions, while South Carolina sees minimal growth.
Researchers at Uppsala University discovered two independent mutations required for the development of sex-linked barring in chickens, a pattern resembling the common cuckoo's plumage. The study sheds light on the genetic mechanisms behind colour variation and pigmentation in birds.
Cin-Ty Lee, an earth scientist at Rice University, has won a Guggenheim Fellowship to investigate how continents emerged from oceans and their effect on nutrient cycling. He will explore crystal growth and kinetics in magmatic and hydrothermal conditions.
A new study by Dartmouth College researchers finds that bipartisan coalitions are more likely to form in Congress when it becomes more polarized, enabling lawmakers to override presidential vetoes. This occurs as party leaders gain control over procedures and presidents use veto power strategically.
A new study confirms denosumab's short-term and long-term safety in treating postmenopausal osteoporosis. Women on long-term treatment experienced no increase in adverse effects compared to those on placebo or shorter treatment durations.
The study reveals that CD38 is essential for postnatal glial cell development, particularly astrocytes. The gene's absence leads to retardation of glial cell development and aberrant interactions among cells, resulting in developmental disorders.
A new parameterization of canopy radiative transfer is proposed, improving the accuracy of land surface radiation models by determining surface albedo and transpiration. The method reveals a relationship between direct and diffuse radiation, treating them separately in previous studies.
A recent study published in the American Journal of Psychiatry found that valbenazine can significantly reduce tardive dyskinesia symptoms in patients with schizophrenia, schizoaffective disorder, and mood disorder. The medication showed a 50% improvement rate compared to the placebo group.
Researchers used a unique wave tank to study wind-generated waves and found that rogue waves are more likely than expected. The experiment provided crucial information on the mathematical likelihood of these extreme events.
A new study compares blood glucose control and hypoglycemia rates between type 1 diabetes patients using insulin pumps versus multiple daily injections during Ramadan. Researchers report improved glucose variability and reduced hypoglycemic episodes with insulin pump therapy.
A study found that less than 50% of eligible women in India take up the Janani Suraksha Yojana scheme due to obstacles such as poor care quality and transport challenges. Community health workers, known as ASHAs, were identified as major enabling factors in accessing delivery care.
Researchers have discovered a protein called PorB, found on the exterior of bacteria, which can increase both antibody production and stimulate cytotoxic T cells to fight off infections. The study demonstrates the potential for this protein to enhance vaccine effectiveness against various diseases, including cancer and HIV.
Biologist Carl-Philipp Heisenberg has been awarded an ERC advanced grant to study the interplay between gene regulatory networks and physical processes in embryonic development. His research will focus on gastrulation, a critical phase of embryonic development where cells are transformed into distinct layers.
A surgical technique has been shown to decrease the severity of tics in young adults with severe Tourette syndrome by an average of 50%. The study, published in Journal of Neurosurgery, adds evidence supporting deep brain stimulation as a safe and effective treatment for severe cases.
Research found that bigger women have a significantly higher risk of atrial fibrillation due to their larger body size, with those in the highest body surface area quartile having nearly three times the risk as those in the lowest. The study's findings suggest that avoiding excess weight may be beneficial for tall individuals.
Researchers developed new engineered PET tracers to image immune checkpoint expression in cancer cells, enabling monitoring of targeted immunotherapy. The study shows practical immunoPET radiotracer design modifications and their effects on human PD-L1 immune checkpoint imaging.
The Graphene Flagship research team has successfully fabricated all-printed, all-layered materials transistors using graphene flakes and other layered materials. This innovation could enable the creation of affordable electronic devices such as smart labels and e-passports.
Research highlights growing challenges faced by older adults in managing medications and finances over time. The study found that rates of needing help with these tasks increased with age, particularly among women and those with certain health conditions.
A team of scientists led by the University of Exeter aims to understand how individual characteristics and social relationships influence collective movements in birds. The project seeks to decipher the mechanisms behind flocking behavior, with potential implications for crowd safety, crop management, and robotics.
A new study found that puffin pairs that migrate close together have higher breeding success rates. Female winter foraging efforts also play a crucial role in determining pair breeding success. The study used geolocators to track the migratory movements of 12 pairs of Atlantic Puffins, revealing that pairs following similar migration r...
Researchers are testing an anti-amyloid drug on people with elevated amyloid levels but no cognitive decline. The goal is to identify an early stage of the disease and delay onset by five years by 2025, which could save billions in healthcare costs.
Researchers have discovered a set of proteins that delays the 'executioner' machinery killing damaged or infected cells in necroptosis. The rescue treatments may prevent injuries to transplanted organs and help prevent cancer spread.
A team of scientists has identified a transcription factor called MYB1 that regulates the lifespan of arbuscules in arbuscular mycorrhizal (AM) fungi. The discovery provides new insights into the molecular basis of balance in AM symbiosis and could lead to more effective symbiosis, potentially improving crop yields.
Tropical Cyclone Ernie strengthened into a hurricane with an eye forming in visible images captured by NASA's Aqua satellite. The storm was located near Western Australia, moving south at 5 knots with maximum sustained winds of 109 mph.
A new study identifies the isotopic fingerprint of nitrous oxide produced by Arctic soils, shedding light on climate change mitigation actions. The research opens up new avenues for predicting future trends in atmospheric nitrous oxide and identifying greenhouse gas sources in the Arctic.
A UC Riverside researcher has received a two-year grant to explore a therapeutic target for IBD patients with TCPTP mutations. The study aims to correct intestinal barrier defects and reduce inflammation in the intestine.
A new bioactive foam can be molded to fit irregular skull defects, attracting bone cells to naturally regenerate bone. The foam hardens in place, providing a low-cost alternative to current bone grafts.
Researchers discovered a previously unknown process involving the melting of intensely-mixed metamorphic rocks, known as mélange rocks, that form through high stress during subduction. This finding changes our understanding of how volcanic arc lavas are formed and may have implications for earthquake studies and volcanic eruption risks.
A University of Alaska Fairbanks study found that warmer Atlantic water is a significant contributor to Arctic sea ice loss. Increased mixing in the Eastern Eurasian Basin allows heat from the warmer water to reach the surface, causing sea ice to melt.
Cognitive biologists found dogs can correctly interpret cues by humans and find hidden food even if they cannot see it. Dogs adopt human perspectives by following gazes and understanding who knows what, enabling them to identify informants and successfully complete tasks.
Scientists have discovered that sea urchins extract calcium ions from seawater through a process where they drink in water and manipulate the ions within their cells. This method is more energy efficient than previously thought, but presents new challenges for understanding how these cells concentrate and expel ions.
Researchers explored genetic similarity between spouses from three generations of white people in the Framingham Heart Study. They found that individuals preferred spouses with the same ancestry, but this preference decreased over time, resulting in a more genetically diverse population.
A clinical trial found that twice-weekly yoga led to better physical, sexual, emotional, and social health in men with prostate cancer. Patients who practiced yoga reported lower fatigue and improved urinary function compared to those without yoga.
Researchers found that bacteria face with limited nutrients will enter an elegant timesharing strategy, alternating feeding periods to reduce competition. The study reveals that structured communities of bacteria use electrical signals to coordinate behaviors and optimize resource utilization.