A study of 9,231 individuals found that those with higher free thyroxine (FT4) levels had an elevated risk of atherosclerotic morbidity and mortality independent of cardiovascular risk factors. Higher FT4 levels were also associated with greater risk of subclinical atherosclerosis.
Thyroid cancer incidence has increased in the US, with higher rates among Hispanics and African Americans compared to non-Hispanic Whites. The study found a significant rise in incidence among young people, particularly Hispanic females between 20-49 years old.
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A study by the Endocrine Society found that higher exposure to certain flame retardants may be associated with an increased risk of papillary thyroid cancer. The researchers collected dust samples from homes and analyzed participants' blood samples to assess long-term exposure to these environmental chemicals.
Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered a potential novel strategy for improving immunotherapy treatments against cancer. By binding two compounds to a nanoparticle, they were able to improve stimulation of T-cells and increase survival rates in preclinical models.
SourceUNC Lineberger Comprehensive Cancer Center·DateApr 1, 2017
Research reveals that consuming cow's milk with levothyroxine supplement can lead to reduced absorption of the medication, potentially resulting in inadequate thyroid hormone levels. The study advises patients on managing hypothyroidism or taking levothyroxine to avoid consuming dairy products simultaneously.
Research suggests that early-life BPA exposure can lead to fatty liver disease by reprogramming gene expression. The study found that BPA creates new activating epigenomic marks on genes driving the progression of NAFLD in rats.
Researchers developed a decision-tree tool to screen women with gestational diabetes for obstructive sleep apnea. The study found that neck circumference was significantly larger in the OSA group, and having a neck circumference greater than 35.5 cm was associated with higher risk for sleep apnea.
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A study found that prolonged sleep disturbance can lead to reduced bone formation and increased osteoporosis risk. After three weeks of cumulative sleep restriction, healthy men had lower levels of a bone formation marker, indicating a potential bone loss window.
UTHealth researchers found that flavored e-cigarettes and marketing are increasing e-cigarette use among youth and young adults. The study also revealed that taste plays a significant role in tobacco products and that advertising can influence e-cigarette uptake among youth.
SourceUniversity of Texas Health Science Center at Houston·JournalTobacco Regulatory Science·DateApr 1, 2017
Researchers have developed selective androgen receptor degraders (SARDs) that can degrade all forms of the androgen receptor, potentially providing advanced treatment options for men with castration-resistant prostate cancer. These molecules inhibit the growth of aggressive prostate cancers that are unresponsive to other treatments.
Exposure to BPS multiplies breast cancer cells, exhibiting estrogen-mimicking behavior, and may cause breast cancer to become more aggressive. The study confirms BPS as a potent endocrine disruptor.
Research suggests that exposure to common pesticides like pyrethroids may cause boys to reach sexual maturity earlier. A study of Chinese boys found a strong association between increased levels of the pesticide metabolite 3-PBA and accelerated puberty, including higher levels of testosterone.
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A study of people with type 2 diabetes found that those with a later sleep-wake time preference reported more depression symptoms, regardless of sleep quality. The findings support an association between circadian regulation and psychological functioning in patients with type 2 diabetes.