Articles tagged with Endocrinology
The Endocrine Society's scientific statement highlights the potential of extracellular vesicles in diagnosing and monitoring endocrine-related conditions, including cancer. These tiny vesicles may also serve as biomarkers for high blood pressure and have therapeutic roles.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that people with type 2 diabetes and cognitive impairment have a higher risk of heart attack and stroke. Cognitive function may predict a person's future risk of heart disease, according to researchers.
The UK National Osteoporosis Guideline Group has published a new guideline for the prevention and treatment of osteoporosis, which includes updated recommendations for vertebral fracture detection and anabolic treatment options. The guidance aims to improve service provision in both primary and secondary care settings.
A new study found that Black people with diabetes were more likely to develop life-threatening complications like diabetic ketoacidosis during the pandemic. The disparity persisted even before the COVID-19 pandemic and was present in 45% of Black people, compared to 16% of White people.
The Virtual WCO-IOF-ESCEO 2022 Congress will feature leading experts on osteoporosis, osteoarthritis, and musculoskeletal diseases, with a focus on new clinical research and advances in prevention and patient care. Prestigious awards will also be presented.
Researchers at Penn Medicine have discovered a new approach to treat solid cancers using CDH17CAR T cells, which selectively target and eliminate gastrointestinal (GI) solid tumors like gastric, pancreatic, and colorectal cancers in preclinical models. Unlike other immunotherapies, CDH17CAR T cells do not show toxicity to healthy tissues.
Professor René Rizzoli has been recognized for his significant and longstanding contribution to the advancement of osteoporosis research through his work on bone metabolism and mineralization. He is a respected researcher, clinician, and leader in the field of osteoporosis, with a strong focus on prevention and treatment.
A UC San Diego study found that excessive neuropeptide secretion by neuroendocrine cells in the lungs can lead to fluid buildup and poor oxygenation in both infant lung disease and COVID-19. Blocking these neuropeptides may be an effective treatment for conditions marked by excess lung fluid.
A study published by The Endocrine Society found that eating potatoes in the morning, whole grains in the afternoon, and less processed meat in the evening may improve long-term survival in people with diabetes. This eating pattern is associated with better heart health outcomes.
Researchers found that long or irregular menstrual cycles in young women are associated with an increased risk of nonalcoholic fatty liver disease (NAFLD). NAFLD is a chronic condition where excess fat builds up in the liver, increasing the risk of death. Lifestyle changes can help reduce the risk of NAFLD in these women.
Research found walkable neighborhoods with access to parks and outdoor activities are associated with a lower risk of obesity and diabetes. Studies showed that living in highly walkable areas reduced the incidence of pre-diabetes by up to 50% compared to low walkability areas.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obesity may increase the risk of end-stage kidney disease in women with type 2 diabetes. Managing blood pressure and sugar levels is not enough to slow progression, emphasizing the need for weight management.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that men with high levels of body fat are more likely to have lower bone density and an increased risk of fractures. The researchers analyzed data from over 10,800 people under 60 years old and found a strong positive association b...
A small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that men with hypersexual disorder have higher oxytocin levels than healthy men. Cognitive behavioral therapy was effective in reducing both hypersexual behavior and oxytocin levels in participants.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that abnormal thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems. Mothers with high thyroid hormone levels were more likely to have withdrawn, anxious, or depressed sons.
A small study published in the Journal of Clinical Endocrinology & Metabolism found that exercising at high altitude can lead to lower blood sugar levels in individuals with type 1 diabetes. This may increase the risk of hypoglycemia, which can be life-threatening if not treated promptly.
Research highlights growing health disparities in diabetes technology adoption between Black and white Medicare patients. Insulin pump and CGM use increased among all groups, but widened gap found between racial groups.
Researchers discovered a new hormone, fabkin, that regulates metabolism and controls insulin production in pancreatic beta cells. Blocking fabkin's activity prevented the development of both forms of diabetes in mice, suggesting its potential as a therapeutic target.
Scientists at Kobe University have successfully generated testosterone-producing Leydig cells from human iPS cells, a significant step towards developing a regenerative medicine treatment for late-onset hypogonadism. The induced cells expressed genes specific to Leydig cells and produced functional testosterone.
The use of dexamethasone has been confirmed as an effective treatment for COVID-19, reducing ICU admissions and deaths by 56%. However, the treatment can increase blood sugar levels in patients with diabetes, highlighting the need for monitoring and potential co-treatments.
Research suggests COVID-19 pandemic has adverse effects on women's menstrual cycles due to stress and sleep disturbance. Women are experiencing increased rates of depression, anxiety, and poor sleep.
A new mobile phone app called GrowthMonitor can accurately measure children's height and detect potential growth disorders, enabling early diagnosis and treatment. The app uses a traffic light system to inform parents of normal, amber, or red growth status, empowering them to take action.
A study published in Nature Communications identified C-terminal binding protein 2 (CtBP2) as a global regulator of metabolism that balances sugar and fat levels in the liver. CtBP2 is crucial for controlling glucose and lipid balance, making it a promising drug target for treating symptoms associated with obesity.
A new study suggests that novel obesity treatments such as modulation of the gut microbiome and gene therapy could help end the obesity epidemic. However, lack of insurance coverage and cost issues create barriers to treatment. Researchers are working on developing safer and more effective medications with fewer side effects.
The Society for Endocrinology's annual conference will feature world-leading scientific and clinical research on endocrine clinical practice. The event will showcase the latest innovations in endocrine medicine, including Medal and Award lectures by renowned experts.
A clinical trial found that a green Mediterranean diet rich in leafy greens like Mankai and green tea can elevate fasting ghrelin levels, reducing belly fat and improving insulin sensitivity. This approach may also have additional cardiometabolic benefits.
A study found that seabirds around the globe consume up to 52% of plastic, leading to accumulation of its chemical components in their bodies. Researchers analyzed oil from preen glands and stomach contents of bird carcasses to determine contaminant burdens.
A systematic review presents evidence that environmental obesogens, such as hormone-disrupting chemicals, play a significant role in childhood and adult obesity. Dr. Leonardo Trasande recommends simple policies to reduce exposure and suggests economic benefits of limiting public exposure.
Researchers explore science behind time-restricted eating, finding it improves sleep quality and reduces obesity, diabetes, and heart disease risk. By aligning daily habits with internal rhythms, intermittent fasting can optimize health and reduce chronic disease burden.
A new study estimates that treating polycystic ovary syndrome (PCOS) costs the US $8 billion a year, primarily due to long-term metabolic health conditions like diabetes and cardiovascular disease. The analysis also found pregnancy-related costs contribute significantly to the total burden.
The energy balance model fails to explain the biological causes of weight gain, whereas the carbohydrate-insulin model identifies excessive consumption of rapidly digestible carbohydrates as a key contributor to obesity. This perspective argues for a shift in focus from calorie restriction to dietary pattern change.
Scientists at Kobe University have created plants that can identify polychlorinated biphenyls and endocrine-disrupting chemicals, which contaminate soil and water. The plant-based method offers a convenient and inexpensive way to monitor toxicity levels.
Experts propose a diagnostic criterion of sustained normal blood sugar levels for three months or more to diagnose type 2 diabetes remission. The long-term effects and relapse rates remain uncertain, highlighting the need for ongoing support and further research.
A preclinical study found that high-fructose diets alter villi in the small intestine, leading to increased nutrient absorption and weight gain. Fructose's primary metabolite promotes elongation of villi and supports intestinal tumor growth.
Researchers discovered that Neuropeptide F (NPF) in fruit flies controls sugar and fat metabolism through glucagon-like and insulin-like hormones. The study reveals similarities between insect and mammalian metabolic processes.
A new University of Warwick-led study found that obese patients over 60 years old can lose an equivalent amount of weight as younger people through lifestyle changes alone. The research aims to correct misconceptions about the effectiveness of weight loss in older people and promote healthy ageing.
Three experts, Professor Maria-Luisa Brandi, Dr. Lee Joon-Kiong, and Professor Ego Seeman, have been awarded the IOF President's Award for their contributions to osteoporosis research, education, and public awareness. The award recognizes their efforts to expand the Foundation's programs and outreach in the scientific and policy spheres.
A study published in Fertility and Sterility found that female reproductive endocrinology and infertility subspecialists make $67,000 less than their male counterparts annually. Researchers attribute the pay gap to factors such as salary compression and women's reluctance to negotiate over salary.
Researchers found that lixisenatide slowed the progression of kidney damage in patients with macro-albuminuria and type 2 diabetes. The study showed a statistically significant reduction in urinary albumin-to-creatinine ratio and a borderline significant reduction in risk of incidence of macroalbuminuria.
Diabetologists are filling a crucial gap in patient care, but their growth is hindered by resistance from payers and colleagues. The new medical specialty aims to provide comprehensive diabetes management, but challenges persist due to reimbursement issues and varying opinions on scope of practice.
Women with insufficient vitamin D levels before pregnancy were more likely to experience miscarriage compared to those with sufficient levels. Vitamin D was found to play a protective role in maintaining pregnancy.
The Champlain BASE eConsult service significantly increased specialty input, with 769 cases in April 2016 compared to four cases in April 2011. Specialists responded within three days in 75% of cases, and the system reduced wait times for specialty care once integrated into practices.
The American Diabetes Association and Michigan Medicine have released updated guidelines for the prevention, treatment, and management of diabetic neuropathy. The guidelines provide recommendations for primary care physicians on preventing this complication and suggest guidelines to manage and treat each form of diabetic neuropathy. Th...
The American Association of Clinical Endocrinologists and American College of Endocrinology have released new osteoporosis guidelines recommending that all postmenopausal women aged 50 and older be evaluated for osteoporosis risk. Successful treatment is defined as stable or increasing bone mineral density with no evidence of new fract...
A randomized trial found that using an activity tracker did not increase physical activity enough to benefit health, even with financial incentives. Despite initial increases in exercise levels, participants stopped using the devices once incentives were removed.
Researchers have discovered that adults born in the 1940s with diabetes are living longer and with less disability, performing day-to-day tasks, compared to those born a decade earlier. This trend is attributed to improvements in diabetes management and healthy lifestyle choices.
Testosterone therapy appears to be safe in the short term, with benefits including improved well-being, decreased gender dysphoria, and reduced breast cancer risk. However, potential undesired effects include acne, alopecia, and increased blood pressure.
A survey of endocrinologists found that while more education and training have been received on transgender care, self-rated comfort levels remain relatively low. Only 20% were 'very' comfortable discussing gender identity and 41% described themselves as competent to provide transgender care.
A revised Society for Endocrinology guideline offers new recommendations for assessing children with disorders of sexual development (DSD), emphasizing the need for multidisciplinary teams, psychological support, and thorough evaluation. The guideline aims to improve diagnosis and treatment outcomes for affected children.
Modeling research suggests that universal iodine supplementation during pregnancy in mildly iodine deficient countries like the UK could save the National Health Service £200 per expectant mother, while providing monetary benefits of around £4500 per child from increased lifetime earnings.
CHOP's Dr. Michael Levine has received the Master of the American College of Endocrinology (MACE) Award for his distinguished career in pediatric endocrinology and diabetes research. He is a world authority on the genetics of parathyroid disease and has published over 250 manuscripts, chapters, and reviews.
A growing number of people will be overweight or obese by 2030, with significant health and economic consequences. The UK's obesity problem requires a multi-disciplinary approach, combining scientific research, environmental factors, personal behavior, and policy interventions.
A new study published in The Lancet Diabetes & Endocrinology found that gradual weight loss is not more effective than rapid weight loss for achieving long-term weight control. In the trial, participants who lost weight quickly were more likely to achieve target weight loss and had lower drop-out rates.
A study of 2342 patients with eating disorders found an increased risk of autoimmune diseases, with 8.9% diagnosed compared to 5.4% in the general population. The findings suggest a link between immune-mediated mechanisms and development of eating disorders.
A genetic study published in The Lancet Diabetes & Endocrinology suggests a causal link between low levels of vitamin D and high blood pressure. The study found that increasing vitamin D levels was associated with a drop in blood pressure and a decreased risk of developing hypertension.
A Canadian study found that women with type 2 diabetes and high cholesterol have poorer LDL cholesterol levels than men, despite equal access to cholesterol-lowering medication. The researchers suggest a need for gender-based evaluation and treatment of cardiovascular risk factors in these patients to prevent heart disease and stroke.
A new meta-analysis suggests that vitamin D supplements do not prevent falls by 15% or more, leaving uncertainty about their benefits for vulnerable older people. The analysis of 20 randomised controlled trials involving over 29,500 participants found no evidence to support the use of vitamin D supplements to reduce fall risk.
A new analysis of 40 randomized controlled trials suggests that vitamin D supplementation does not prevent heart attacks, strokes, or bone fractures. The study concludes that vitamin D supplements probably provide little to no health benefit, contradicting previous observational studies that linked deficiency to poor health.
Researchers found that mild cold exposure can significantly affect energy expenditure over sustained time periods, suggesting a potential benefit for weight loss. Brown fat, a heat-generating organ thought to be active only in infants, is also present in adults and can be activated by cold temperatures.
Researchers created the first risk score predicting 10-year dementia risk for type 2 diabetes patients based on medical history and electronic health records. The Diabetes-Specific Dementia Risk Score assigns a value to eight predictive factors, including microvascular disease and diabetic foot.