A new scale for reproductive aging in Chinese women has been developed based on ultra-sensitive AMH testing. The scale provides age-specific percentiles for AMH levels in women aged 35-55, enabling earlier identification of women at risk of low ovarian reserve and better management of perimenopausal symptoms.
A new Cochrane review has found that emergency contraception containing mifepristone is more effective than other common methods, such as levonorgestrel, with fewer side effects. Mifepristone also showed a lower risk of nausea and vomiting compared to other methods, but a higher likelihood of delayed menstruation.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateSep 20, 2026
The Society of Pelvic Surgeons (SPS) has selected The GOG Foundation, Inc. as its management partner to advance multidisciplinary surgical collaboration worldwide. This partnership aims to strengthen member engagement, expand the society's visibility, and build upon its legacy.
Researchers found that girls whose mothers took paracetamol during pregnancy had smaller ovaries, fewer ovarian follicles, and lower levels of reproductive hormones at three months old. The study, published in Human Reproduction Open, suggests that foetal exposure to paracetamol may affect reproductive development, but the findings do ...
Immunotherapy for gynecological tumors offers durable responses and survival benefits, but complex immune evasion mechanisms and tumor microenvironment pose challenges. Current treatment options, such as ICIs and adoptive cell therapy, show promise, but precision immunotherapy is needed to improve patient outcomes.
A study published in JAMA Network Open reveals that nearly 1 in 3 women in their 20s have never been screened for cervical cancer, with 45% of this age group unvaccinated against HPV. The trend is particularly concerning among uninsured women, those living in the South, and racial minorities.
A large UK study found that hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for women who have undergone surgical menopause. The study, which followed over 180,000 postmenopausal women, found that HRT was associated with a 16% lower risk of developing Alzheimer's disease compared to non-users.
PCORI awards funding for new patient-centered comparative clinical effectiveness research, addressing key healthcare questions and generating evidence for better-informed decisions. The projects will focus on emergency, hospital, and surgical care, as well as mental and behavioral health, to improve health outcomes.
A study of 2,400 women found that high folic acid intake was associated with vaginal bleeding in early pregnancy, especially in pregnancies carrying a boy. Women taking 800 micrograms or more of folic acid per day were more likely to experience spotting and mild bleeding during the first 16 weeks of pregnancy.
A recent study by HKUMed predicts a 50% increase in global infertility cases among women aged 35-49 by 2036, with East Asia bearing the highest burden. The research emphasizes the need for early fertility planning, assessment, and prevention to mitigate the growing health challenge.
A study analyzing US women's data found a significant association between high antioxidant intake and lower cervical cancer prevalence. The researchers discovered a linear inverse association between the Composite Dietary Antioxidant Index and cervical cancer, suggesting potential prevention benefits.
A study of 120 women found that severe pelvic floor and anorectal symptoms are associated with more severe depressive symptoms and lower self-esteem. Chronic symptoms can lead to social isolation, reduced participation, and a sense of losing control over one's body.
UC San Diego Health has been ranked as the top care facility in California and among the top 20 in the nation for eight medical specialties. The institution achieved this distinction through its patient-dedicated, collaborative spirit and commitment to delivering outstanding care.
The new position statement offers practical recommendations for the assessment, diagnosis, and management of PLO. It recommends individualized management, including pharmacological treatment where appropriate.
A national study of obstetrician-gynecologists reveals that state abortion laws are linked to higher levels of clinical constraints and moral distress among OB-GYNs. The findings suggest that institution-level support is needed to address moral distress, regardless of the state's abortion policy context.
A rare case report highlights the challenges of diagnosing cervical angioleiomyoma, a benign tumor presenting symptoms similar to those of common gynecological conditions. The study describes a successful surgical excision and excellent clinical outcome for a young woman with persistent heavy menstrual bleeding and pelvic pain.
A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, researchers reveal. The study found that replenishing beneficial bacteria or treating patients with FDA-approved bile acid sequestrants may reduce breast cancer metastasis.
Women who experience violence are more likely to reach the menopause earlier and exhibit severe hot flushes, anxiety, and depression. Trauma also exacerbates systemic health issues such as hypertension, diabetes, and bone loss, creating a 'hidden burden' of morbidity.
Researchers discovered microtubules within transzonal projections, which connect granulosa cells and oocytes, facilitating communication. The study reveals Camsap3 stabilizes microtubules, essential for maintaining granulosa cell-oocyte communication and female fertility.
A young woman's quality of life and ability to walk were restored after a specialized procedure at Semmelweis University. The laparoscopic removal of a rare, benign tumor of neurological origin in the lesser pelvis, known as a schwannoma, was performed using intraoperative electrophysiological monitoring.
Scientists have identified a unique chimeric RNA called UBA1-CDK16 that plays important roles in women's blood cell development and disease severity. The findings suggest the chimeric RNA may serve as a natural brake to protect women from excessive autoimmune activity.
Jacques Ravel has been recognized for his foundational contributions to understanding the human vaginal microbiome, its links to pregnancy outcomes and susceptibility to infection. His work also laid the groundwork for live biotherapeutics designed to shape the vaginal microbiome in ways that could improve pregnancy outcomes.
A study of 165,832 women found that later menarche is associated with an increased risk of tobacco use disorder and various conditions, including digestive issues, heart problems, and brain disorders. The researchers suggest a shift in perspective to recognize childhood influences as the primary cause of adult health problems.
The Mount Sinai Health System has opened the Carolyn Rowan Center for Women’s Health and Wellness, which brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research to deliver personalized, comprehensive care for women. The Center offers guided multi-visit experiences and coordinated care o...
Two projects, BOOST-HP and BIONIC, use machine learning to analyze large datasets of medication exposure and outcomes. The findings highlight the need for more data and cautious design of machine learning models to accurately assess potential links between medications and pregnant women.
Polyendocrine Ovarian Syndrome (PMOS) impacts 13% of women, causing hormonal imbalance, insulin resistance, and chronic pain. Lifestyle interventions, particularly diet and exercise, show benefits for physical and mental health outcomes.
A study by Osaka Metropolitan University found that women with a higher proportion of LOX cells in their white blood cells had a lower likelihood of achieving natural pregnancy. The researchers suggest combining AMH analysis with LOX measurement may improve prediction of natural conception.
Pelvic organ prolapse affects up to half of all women, causing incontinence and chronic pain. A new survey reveals one in three women suffer in silence due to common misconceptions about the condition.
The condition is recognized as a complex, multisystem disorder involving endocrine, metabolic, reproductive, dermatological, and psychological health. The new name, PMOS, is expected to reshape how the condition is diagnosed, treated, and researched globally.
Researchers present findings on sociodemographic disparities in hypertensive disorders of pregnancy, highlighting the need for better characterization and management of these conditions. Dr. Basma S. Faris discusses reframing PCOS as a chronic disease requiring longitudinal care.
A new study published in the American Journal of Obstetrics and Gynecology finds that approximately 11.8% of reproductive-age Latina women have fibroids, lower than previously estimated rates. The study, led by Michigan Medicine researchers, used ultrasound-confirmed diagnoses to confirm fibroid cases.
The Yōni.Fit device is FDA-cleared for temporary management of stress urinary incontinence and also collects menstrual fluid and/or vaginal discharge. Clinical trials show a 96% clinically significant reduction in SUI bladder leaks.
Professor Radmila Matijevic received the IOF CNS Medal for her outstanding work in advancing bone health awareness, diagnosis, and management. Her contributions to osteoporosis research and clinical practice have improved patient care in Serbia and the wider Balkan region.
Twenty-three young investigators from 16 countries received the ESCEO-IOF Young Investigator Awards for their outstanding abstracts submitted to the WCO-IOF-ESCEO 2026 Congress. The awards aim to support and attract young researchers to the field of musculoskeletal research.
A clinical trial aims to evaluate whether laser therapy reduces vaginal dryness caused by breast cancer treatment. The study, REVITALIZE, plans to enroll approximately 250 women with a history of breast cancer who experience moderate to severe vaginal dryness.
The phase III NRG GY019 trial found that paclitaxel/carboplatin followed by letrozole is the standard treatment for patients with stage II-IV low-grade serous ovarian carcinoma. The study also showed that letrozole monotherapy did not demonstrate non-inferiority to the combination, but was associated with fewer serious side effects.
Researchers developed an immune-capable 'cervix-on-a-Chip' model to study sexually transmitted infections (STIs), enabling a more accurate understanding of these conditions and the potential for better treatments. The model replicated key aspects of human biology, including the cervical microenvironment, microbiomes, and immune system.
A study from the Ragon Institute reveals how a live bacterial therapy works to prevent recurrent bacterial vaginosis (BV) and why it works better for some women than others. The therapy, LACTIN-V, was found to successfully colonize the beneficial bacterium Lactobacillus crispatus in 30% of women, leading to improved vaginal health.
Dr. Emily Lukacz has been named the 2026 President of American Urogynecologic Society, a prestigious position that recognizes her innovative leadership in the complex field of urogynecology. As president, she aims to streamline treatment by educating primary care providers and allied health professionals.
Researchers found that mild hypoxia in preterm babies can compromise neural communication, impacting the hippocampus region responsible for memory and learning. Abnormal neuronal maturation and loss of synaptic function may lead to academic difficulties and behavioral concerns later in life.
A new platform, Build Better Bones, offers evidence-based guidance and practical resources for osteoporosis management. The platform, developed by the International Osteoporosis Foundation, provides a trusted place for people with osteoporosis to start their journey, with a focus on exercise, nutrition, and home safety.
The Society of Interventional Radiology has published new practice guidance for treating chronic pelvic pain in women with venous-origin disorders, emphasizing interventional radiology's role in care. The guidance provides evidence-based recommendations on diagnosis, treatment options, and imaging.
A study found that Targeted Regulation of Abortion Providers (TRAP) laws significantly reduced the supply of obstetricians and gynecologists, particularly older and newly trained doctors. This led to a decline in more than 2 obstetrician-gynecologists per 100,000 females aged 15–44 years.
A nationwide study found that periods can trigger severe pain in many women and girls with sickle cell disease, leading to emergency department visits and hospitalizations. The study's authors recommend a routine menstrual history screening as part of annual sickle cell care and connecting patients with reproductive health specialists.
A new review highlights the need for planned sequential bone therapy to reduce the risk of spontaneous vertebral fractures after denosumab therapy. Denosumab discontinuation can trigger a 'rebound phenomenon' marked by rapid bone turnover, bone loss, and potentially multiple vertebral fractures.
Ovarian cancer cells recruit protective mesothelial cells in abdominal fluid to form hybrid cell clusters that resist chemotherapy. These clusters use spike-like structures called invadopodia to invade surrounding tissue. The discovery opens new treatment possibilities and could help doctors monitor disease progression.
Researchers at the University of Maryland School of Medicine discovered 25 distinct vaginal microbiome types, challenging the long-standing view of a simplified
A research team has identified eleven novel factors essential for mouse zygote development, which modulate embryonic development through precise mechanisms. These findings suggest the existence of previously unrecognized regulatory factors and indicate potential for molecular-level control of embryo development.
A new study found that only a quarter of reproductive health experts prescribe self-administered injectable contraceptives, despite its safety and effectiveness. The study identified barriers such as concerns about patient ability, medication availability, and lack of standardized counseling approaches.
A recent study has found that rates of opioid use during pregnancy have risen two-fold over the past decade, with significant increased risks of maternal and infant health complications. The study emphasizes the urgent need for accessible, wraparound health care for mothers and families affected by opioid addiction.
A new study published in JAMA Oncology found that the HPV vaccine can protect against severe precancerous lesions of the vulva and vagina. Vaccination before the age of 17 offers the strongest protection, with a 55% lower risk compared to unvaccinated women.
Researchers found that Asian and Singaporean women with PCOS have better reproductive outcomes, including higher pregnancy rates and oocyte retrieval per cycle, compared to women without PCOS. Women with PCOS tend to maintain a higher ovarian reserve as they age, allowing for more robust responses to fertility treatment.
The Icahn School of Medicine at Mount Sinai is advancing women's health through cutting-edge research and compassionate care, with a focus on addressing knowledge gaps and promoting seamless treatment journeys. The institution joins the Milken Institute's Women's Health Network to bring its expertise in clinical excellence, research in...
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A new study from the University of Southern Denmark reveals that depression is significantly more common among women with gynaecological disorders—both before and after receiving a diagnosis. The study highlights the need for earlier detection and a more integrated approach between somatic and psychiatric care.
A survey by Ohio State University Wexner Medical Center reveals that nearly all Americans are unaware of the comprehensive women's health services provided by certified nurse-midwives. Only 20% know about annual gynecology exams, while 93% are aware of pregnancy and birth support.
The 9th IOF Asia-Pacific Bone Health Conference will bring together healthcare professionals, researchers, and policymakers to exchange knowledge and shape the future of bone health across the region. The conference will feature keynote lectures, sponsored sessions, and a launch of the IOF Asia-Pacific Regional Audit 2025.
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
Researchers Drs Emmanuel Bujold and Roberto Romero propose a new closure technique for cesarean delivery that respects the natural anatomical structure of the uterus. This approach may reduce long-term complications such as abnormal placenta attachment, uterine rupture, and pelvic pain.
A recent Finnish study found an association between severe nausea during pregnancy and depression, both before and after childbirth. Women who experienced severe nausea were more likely to develop depression and receive earlier diagnoses.