Articles tagged with Gynecology
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A research team has identified eleven novel factors essential for mouse zygote development, which modulate embryonic development through precise mechanisms. These findings suggest the existence of previously unrecognized regulatory factors and indicate potential for molecular-level control of embryo development.
A new study found that only a quarter of reproductive health experts prescribe self-administered injectable contraceptives, despite its safety and effectiveness. The study identified barriers such as concerns about patient ability, medication availability, and lack of standardized counseling approaches.
A recent study has found that rates of opioid use during pregnancy have risen two-fold over the past decade, with significant increased risks of maternal and infant health complications. The study emphasizes the urgent need for accessible, wraparound health care for mothers and families affected by opioid addiction.
A new study published in JAMA Oncology found that the HPV vaccine can protect against severe precancerous lesions of the vulva and vagina. Vaccination before the age of 17 offers the strongest protection, with a 55% lower risk compared to unvaccinated women.
Researchers found that Asian and Singaporean women with PCOS have better reproductive outcomes, including higher pregnancy rates and oocyte retrieval per cycle, compared to women without PCOS. Women with PCOS tend to maintain a higher ovarian reserve as they age, allowing for more robust responses to fertility treatment.
The Icahn School of Medicine at Mount Sinai is advancing women's health through cutting-edge research and compassionate care, with a focus on addressing knowledge gaps and promoting seamless treatment journeys. The institution joins the Milken Institute's Women's Health Network to bring its expertise in clinical excellence, research in...
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A survey by Ohio State University Wexner Medical Center reveals that nearly all Americans are unaware of the comprehensive women's health services provided by certified nurse-midwives. Only 20% know about annual gynecology exams, while 93% are aware of pregnancy and birth support.
A new study from the University of Southern Denmark reveals that depression is significantly more common among women with gynaecological disorders—both before and after receiving a diagnosis. The study highlights the need for earlier detection and a more integrated approach between somatic and psychiatric care.
The 9th IOF Asia-Pacific Bone Health Conference will bring together healthcare professionals, researchers, and policymakers to exchange knowledge and shape the future of bone health across the region. The conference will feature keynote lectures, sponsored sessions, and a launch of the IOF Asia-Pacific Regional Audit 2025.
Research shows that infants of stressed mothers have an earlier and faster tooth eruption, with more teeth by six months of age. Cortisol levels during late pregnancy are associated with this accelerated process.
A recent Finnish study found an association between severe nausea during pregnancy and depression, both before and after childbirth. Women who experienced severe nausea were more likely to develop depression and receive earlier diagnoses.
Researchers Drs Emmanuel Bujold and Roberto Romero propose a new closure technique for cesarean delivery that respects the natural anatomical structure of the uterus. This approach may reduce long-term complications such as abnormal placenta attachment, uterine rupture, and pelvic pain.
ADCs use targeted antibodies to deliver cytotoxic payloads directly into cancer cells, destroying tumors while minimizing harm to healthy cells. Two ADCs have been approved by the FDA for gynecological cancer treatment, and numerous others are in clinical trials.
A rare case of a mucinous vulvar cyst was reported, which resembled a benign lipoma and caused lower abdominal and back pain. The cyst was surgically removed and confirmed to be non-malignant. The case underscores the importance of careful clinical examination in reproductive-age women presenting with vulvar masses.
Lactate accumulation drives lactylation, a critical post-translational modification promoting tumor proliferation, metastasis, and therapy resistance. Emerging strategies targeting lactate production, transport, and lactylation hold significant anticancer potential.
The FDA has approved elinzanetant for treating hot flashes and night sweats in postmenopausal women. The drug significantly reduces the frequency and severity of symptoms while improving sleep quality and quality of life.
A national survey of first-year fellows in minimally invasive gynecologic surgery found significant gaps in the use of FDA-cleared containment systems during laparoscopic hysterectomy and myomectomy. The majority of fellows cited cost as the main reason for using less expensive, off-label retrieval bags instead of FDA-cleared systems.
Paul N. Staats, MD, has been appointed Chair of the University of Maryland School of Medicine's Department of Pathology, overseeing clinical services to multiple hospitals and laboratories. He will drive partnerships and expand outpatient laboratory services.
A new study found that over 40% of specialty clinics in the US turn away patients weighing 465 pounds or more due to lack of accessibility features. The study highlights a need for staff training on inclusive care and accommodations for patients with severe obesity.
A large international clinical trial found that elinzanetant significantly reduces hot flashes and night sweats in postmenopausal women by over 73%. The drug also shows secondary benefits such as improved quality of life and reduced sleep disturbances, with no harmful effects on the liver or bone density.
A landmark study found gestational diabetes during pregnancy is associated with declines in intellectual function for mothers and higher risks of developmental, behavioural and autism spectrum disorders in children. Mothers with GDM scored 2.47 points lower on cognitive assessments than peers without GDM.
Dr. Wendaline M. VanBuren has been awarded a grant to develop an AI-powered model for diagnosing and treating adenomyosis and endometriosis. The study aims to enhance detection, treatment planning, and patient outcomes.
The International Osteoporosis Foundation identifies critical global barriers to osteoporosis care, including limited DXA scanning and outdated treatment criteria. The IOF advocates for a paradigm shift in bone health management worldwide, recognizing high fracture risk as a valid criterion for treatment and reimbursement.
According to UMass Amherst research, only 16% of US counties offer access to vaginal labor after C-section. Despite the American College of Obstetricians and Gynecologists' guidelines supporting this option, access remains limited due to factors such as hospital availability and provider comfort.
A new study in the American Journal of Preventive Medicine found that two-thirds of women of reproductive age in the US have at least one modifiable risk factor for birth defects. The analysis highlights the need for improved preconception health and identifying and addressing these changeable risk factors before pregnancy.
Dr. Catheryn Yashar, a renowned radiation oncologist, has been appointed president-elect of the American Society for Radiation Oncology (ASTRO). She will champion innovative radiation therapies and advance health policy reform to improve cancer care outcomes.
The International Osteoporosis Foundation has issued an updated joint position statement on managing aromatase inhibitor-associated bone loss in women with hormone-sensitive breast cancer. The guidelines incorporate recent clinical trials and systematic reviews to provide evidence-based treatment algorithms for assessing fracture risk ...
Extracellular vesicles play a crucial role in regulating oocyte maturation, follicular growth, and quality. In pathological conditions, EVs can disrupt communication, leading to impaired oocyte development and ovarian failure. Therapeutic EVs show promise in reversing ovarian pathologies by delivering functional molecules.
A pediatric investigation study reveals that male fetuses prioritize growth while female fetuses focus on placental development under gestational hypertension. The findings support the growth strategy hypothesis and suggest sex-specific differences in fetal responses to prenatal stressors.
The Mount Sinai Hospital has been listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, with top-10 rankings in five specialties and top-20 rankings in nine. The hospital was also rated High Performing in all 22 procedures and conditions assessed by U.S. News.
A new study suggests that offering self-collection kits during routine GP appointments can increase participation rates among women overdue for cervical screening. The approach shows promise in reducing the number of cases and saving lives.
A recent clinical trial found MyMenoplan.org effective in increasing treatment intentions and menopause knowledge among users. The website offers personalized information and decision-making tools, guiding women through symptom discussions and outlining treatment options.
A study of 6 million women found that stopping menopausal hormone therapy (MHT) leads to a higher risk of bone fractures, particularly in the first three years. The fracture risk then decreases over time and becomes similar to that of women who never used MHT.
A new study by University College London found that nearly 58% of women who had given birth in the last year were not using contraception two months later, despite the risk of back-to-back pregnancies. Women who received high-quality contraceptive advice were more likely to use contraception sooner after giving birth.
A study found that a grandmaternal age difference of ≤-9 years significantly increases the risk of pregnancy cardiometabolic disorders. The researchers analyzed data from 2,235 grandmother-mother pairs and discovered a nonlinear association between age differences and CMDs.
A new study found that moderate caloric restriction can preserve youthful ovarian follicles and reduce age-related tissue stiffness in rhesus macaques. This suggests that lifestyle-based strategies may help delay the decline in reproductive function associated with aging.
A recent study at the University of Jyväskylä found that central adiposity increases the risk for stress urinary incontinence in middle-aged women. Larger fat mass and waist circumference are key factors associated with this increased risk, highlighting the importance of body composition in understanding pelvic floor disorders.
A new study found a significant association between hyperinsulinemia and abnormal uterine bleeding, with body mass index playing a unique role. The study suggests that addressing insulin resistance and obesity may be key to preventing abnormal uterine bleeding.
MenstruAI analyzes menstrual blood to detect disease biomarkers, offering an early warning system for women's health. The technology uses a paper-based test strip and smartphone app to analyze protein concentrations.
A new prediction model developed by researchers at the University of Gothenburg has been found to accurately assess the risk of severe birth injuries during childbirth. The study's findings suggest that larger babies are the main risk factor for these injuries, and previous obstetric anal sphincter injuries also play a significant role.
Researchers will discuss increasing the use of low-dose aspirin for preeclampsia prevention through universal implementation. Additionally, experts will present on the impact of doula care on social determinants of health, exploring its potential to address non-medical healthcare disparities within the system.
Yōni.Fit demonstrated significant reduction in 12-hour pad weights spanning seven days compared to the control device, highlighting its superior performance. The study showed mild to moderate adverse events, but no serious ones.
A Phase III trial shows molecular profiling can safely reduce radiation for women with early-stage endometrial cancer, tailoring treatment to individual tumour characteristics. Nearly half of patients can be spared radiotherapy without compromising cancer control.
The IOF Advanced Course on Osteoporosis is a comprehensive, 18-hour online training programme designed to equip healthcare professionals with the latest knowledge in osteoporosis prevention, diagnosis, and management. The course aims to promote timely diagnosis and treatment, reduce patient burden, and improve global outcomes.
Research from the University of Oklahoma suggests that women with adequate iron levels in their blood perform better on cognitive tasks during menopause. Having enough iron does not necessarily mean accumulating more iron in the brain, which is a risk factor for neurodegenerative diseases like Alzheimer's.
A new study from the University of Missouri School of Medicine reveals that disruptions in cell communication can lead to disease progression in the uterus. Basal cells, typically found in healthy tissues, may be indicative of cancer or other diseases, highlighting the importance of early detection and prevention.
Dr. Elizabeth M. Curtis has been awarded the ESCEO-IOF Pierre Meunier Young Scientist Award for her groundbreaking research on musculoskeletal health and bone disease. Her work focuses on the epidemiology of bone, muscle health, and joint health across the lifespan.
Dr Ambrish Mithal, an Indian endocrinologist, has been awarded the prestigious IOF CSA Medal of Achievement for his groundbreaking work in advancing the field of osteoporosis. His pioneering efforts have significantly increased understanding and awareness of osteoporosis globally.
Researchers have discovered a significant increase in inflammation and C-reactive protein levels in female patients with sickle cell disease during the follicular phase of their menstrual cycle. This finding may help identify potential targets for managing pain crises, particularly when combined with hormonal contraceptives.
A survey of 1,068 women reveals that many believe they will hit menopause in their 40s, despite symptoms starting earlier. Experts emphasize the importance of addressing changes and concerns with a doctor to find effective treatment options.
A systematic scoping review reveals substantial inequities in gender representation among US academic medical center leaders. Despite female-dominated specialties, women are largely excluded from leadership positions across various niches of academic medicine.
Endometriosis is a painful and infertility-Linked condition that affects millions of women worldwide. New research by MSU professors identifies key cellular cross-talk that could lead to better non-hormonal treatments.
A new study reveals a cell atlas of the endometrium in women with PCOS, showing distinct differences in cellular composition and gene expression. The findings suggest that targeting specific cell types may lead to better treatment options for women with PCOS and related reproductive issues.
Patients from American Indian and Black communities are less likely to have elevated CA-125 levels at diagnosis, suggesting current thresholds may miss diverse patients. Inclusive diagnostic guidelines are needed to address disparities in ovarian cancer diagnosis and treatment.
The NRG Oncology GOG-0263 phase III clinical trial found that adding cisplatin-based chemotherapy to adjuvant radiotherapy following radical hysterectomy did not improve outcomes and led to increased toxicity. Radiotherapy alone remains the standard of care for early-stage, intermediate-risk cervical cancer.
A combination therapy of FTH-001 (serabelisib) and FTH-003 (sapanisertib) with paclitaxel is being investigated in a Phase 2 trial for patients with advanced or recurrent endometrial cancer. The trial aims to target the PI3K/AKT/mTOR pathway, which is frequently mutated in cancer.
The Dobbs decision has been linked to moderate but significant decreases in obstetrics and gynecology practitioners in the most restrictive states compared to control states. Clinician migration is likely affecting reproductive care access, quality, and equity as abortion rights are increasingly decided at the state level
A Japanese study found that smoking during pregnancy increases the risk of placental abruption by 2.8%, while second-hand smoke exposure contributes an additional 3.0% risk. The study highlights the importance of preventing all smoke exposure in public spaces and homes to safeguard maternal and fetal health.
A study from the University of Missouri found that rural first-time moms are more likely to stop breastfeeding due to a lack of practical knowledge, community support, and access to lactation consultants. The research aims to improve support and resources for new mothers in rural areas.