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JCI table of contents, 1 June 2004

A new study suggests that using stents to open blocked blood vessels in branching passages can lead to a harmful blood flow pattern, resulting in rapid re-occlusion of the main branch. This contradicts previous findings that suggest stenting was more successful in non-bifurcated areas.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 1, 2004

Staph infection process leading to B cell suicide described by UCSD researchers

UCSD researchers found that the Staph protein SpA triggers a pre-emptive attack on B cells, leading to their death and preventing them from developing memory cells. This process may explain why staph infections are common and recurring. The study's findings have potential applications in treating autoimmune diseases and cancers.

SourceUniversity of California - San Diego·JournalJournal of Experimental Medicine·DateApr 28, 2003
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Infections may trigger autoimmunity via rare, but normal process

A study by The Wistar Institute suggests that infections can trigger autoimmunity through a normal but rare process involving memory B cells. A transgenic mouse with a self-similar influenza gene led to an autoimmune response, showing that the immune system may not eliminate all self-reactive cells.

SourceThe Wistar Institute·DateDec 18, 2000