Growth Hormone
Articles tagged with Growth Hormone
World Hormone Day 2026
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
New study identifies growth hormone receptor as possible target to improve lung cancer treatment
Researchers at Ohio University discovered that blocking the growth hormone receptor may help make lung cancer treatments more effective. Patients with low GHR tumors survived significantly longer than those with high GHR tumors, highlighting a potential new target for therapy.
A delicate balance between growth hormone and stem cells
Growth hormone directly controls behavior of stem cells in growth plate, stimulating growth but also depleting cartilage stem cells. This delicate balance is crucial for long-term bone development and may contribute to refining growth hormone treatments.
Hormone-disrupting chemicals from plastics shown to promote a chronic inflammatory skin condition
A Johns Hopkins Medicine study found hormone-disrupting chemicals shed by plastics are present in the skin of people with hidradenitis suppurativa, potentially worsening symptoms. The researchers believe reducing exposure could ease HS symptom severity and provide a new avenue of relief.
How growth hormone excess accelerates liver aging via glycation stress
Researchers found that excess growth hormone disrupts liver metabolism, leading to molecular and cellular patterns similar to those in naturally aged livers. Reducing glycation stress can reverse these negative effects, improving liver health and physical function.
New EndoCompass Research Roadmap calls for coordinated investment to tackle Europe’s hormone health challenge
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Sleep strengthens muscle and bone by boosting growth hormone levels. Here's how
A new study reveals the complex brain circuits involved in growth hormone release during sleep. The findings provide a map for understanding how sleep and hormone regulation interact, potentially leading to new treatments for sleep disorders and degenerative diseases.
Study finds strong link between acromegaly and increased cancer risk
A new study by The Endocrine Society finds a strong link between acromegaly and an increased risk of various cancers, often at younger ages than expected. Patients with the rare growth hormone disorder had higher rates of certain types of cancer, including colon, gastric, breast, lung, ovarian, prostate, and blood cancers.
Emotional health of parents tied to well-being of children with growth hormone deficiency
A study by The Endocrine Society reveals that children with growth hormone deficiency experience improved overall health and coping mechanisms when their caregivers report reduced stress, anxiety, and depression. Conversely, caregivers' emotional stability is associated with better outcomes for the child.
Manuel Heitor to share perspectives on the future of research in Europe at launch of EndoCompass
The EndoCompass project aims to guide future studies and funding programs with a research roadmap for better hormone health in Europe. Manuel Heitor will share his perspective on the future of research in Europe, emphasizing the need for greater investment and coordination.
Omega-6 fatty acid promotes the growth of an aggressive type of breast cancer
A preclinical study found that linoleic acid, an omega-6 fatty acid, activates a major growth pathway in tumor cells, particularly in triple-negative breast cancer subtypes. A high-linoleic-acid diet enhanced tumor growth in mice with triple-negative breast cancer.
Delay of more than 42 days for breast cancer surgery raises death risk for certain subtypes, University of Oklahoma study finds
Patients with hormone receptor-positive and HER2-negative breast cancers face a higher risk of death from the cancer if they wait more than 42 days after diagnosis to have surgery. Delayed surgery increases the patient's risk exponentially, with risks of death increasing by 21%, 79%, and 183% at 60, 90, and 120 days, respectively.
New insights into plant growth
A recent study revealed that brassinosteroids are distributed unevenly between new cells formed during cell division, influencing root growth and development. The findings provide a comprehensive understanding of how these hormones regulate plant growth and development at the cellular level.
Communication between body muscle and the brain influences fertility, study finds
Researchers at McGill University found that a protein produced in muscles helps manage the release of follicle-stimulating hormone (FSH), which promotes egg maturation. Lowering myostatin levels delayed puberty and reduced fertility, while restoring it boosted FSH levels.
Boosting this molecule could help retain muscle while losing fat
A new study from the Salk Institute has discovered that a protein called BCL6 plays a crucial role in maintaining healthy muscle mass. Increasing BCL6 levels successfully reversed muscle losses in mice, suggesting that pairing GLP-1 medications with a BCL6-boosting drug could help counteract unwanted muscle loss.
Save the date: European Society of Endocrinology (ESE) and ESE Foundation announce inaugural World Hormone Day
The European Society of Endocrinology (ESE) and ESE Foundation will host the first-ever World Hormone Day on April 24, 2025. The campaign aims to raise public awareness of good hormone health and improve national political engagement for better prevention, diagnosis, and treatment of endocrine disease.
Study: Tumors grow larger in female fruit flies than males. Here’s what that could mean for humans
A study by Tulane University researchers found that tumors in female fruit flies grew 2.5 times larger than those in male fruit flies due to sex-based differences in immune response. The stronger innate immune response in females accelerated tumor growth.
Pioneering neuroendocrinologist shapes brain research at 100 while still making discoveries
Dr. Seymour Reichlin's centennial celebration highlights his ongoing scientific impact, with recent collaborations yielding new insights into hormone therapies for cognitive enhancement and emotional homeostasis. His work has established neuroendocrinology as a distinct field, bridging neuroscience, endocrinology, and clinical medicine.
Chinese Medical Journal study reveals key insights on the global burden of thyroid cancer in 2022
A study published in the Chinese Medical Journal projects a significant rise in global thyroid cancer burden, with 821,214 new cases and 47,507 related deaths reported worldwide in 2022. The incidence is expected to increase by 44.1% from 2019 to 2030, with women experiencing higher rates than men.
Researchers separate plant growth and disease resistance
Researchers have identified a promising approach to addressing the challenge of balancing disease resistance and plant growth. By modifying cold-regulated genes, they were able to decouple the salicylic acid-growth trade-off, allowing plants to maintain normal growth even with elevated acid levels.
Shape-shifting WVU robot inspired by insect swarms and tree roots is teaching itself to mark contamination zones
The WVU team, led by Yu Gu, is testing Loopy's ability to 'co-design' itself and learn to mark contaminated areas. Inspired by natural phenomena like ant swarms and tree roots, Loopy changes form in response to its environment.
Advanced biosensor uncovers role of gibberellin in integrating light signaling and stem growth in plants
Researchers at the University of Cambridge have discovered that gibberellin hormone plays a crucial role in integrating light signaling and stem growth in plants. Using advanced biosensors, they found that gibberellin levels are higher in longer cells and that a specific enzyme called GA20ox1 produces a gradient that controls cell elon...
Next generation biosensor reveals gibberellin’s critical role in legume nitrogen-fixation – paving the way for more productive legume crops and self-fertilizing cereals
Researchers at the University of Cambridge have discovered that the plant hormone gibberellin is essential for legume nitrogen-fixing root nodule formation and maturation. The study used a highly sensitive next-generation biosensor to visualize GA accumulation in specific zones of the root, revealing its critical role in nodulation.
New study shows medication abortion without ultrasound to be safe
A new study by UC San Francisco's ANSIRH program found that patients who received care remotely for medication abortion had similar outcomes to those who got ultrasounds and in-person care. The researchers analyzed the experiences of over 500 patients and found a high success rate for the
Now we know, what gets roots to grow: Can help in future droughts
Researchers from the University of Copenhagen discovered that a biological mechanism called autophagy plays a key role in plant root growth. By understanding how plants control their root growth, scientists can develop climate-resilient crops to thrive in harsh conditions.
Sending abortion pills through the mail is timely and effective
Researchers at UC San Francisco found that dispensing abortion pills through the mail is a safe and effective method, with nearly 98% of patients completing their abortions. The study suggests that this model can help increase access to abortion care for clinicians and patients alike.
People with rare longevity mutation may also be protected from cardiovascular disease
A recent study found that individuals with a rare condition known as growth hormone receptor deficiency (GHRD) have normal or improved levels of cardiovascular disease risk factors compared to their relatives. This suggests that GHRD may actually protect against cardiovascular disease, contrary to previous speculation.
Exploring the role of MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia
Researchers discovered MIA-602's effectiveness against Doxorubicin-resistant acute myeloid leukemia (AML), demonstrating reduced cell viability and tumor volume. The study suggests MIA-602 as a potential alternative treatment approach for AML, potentially circumventing chemotherapy side effects.
New insights into cholesterol dynamics shed light on neurodegenerative disease
A study published in PNAS reveals the structure of a protein linked to neurodegenerative disease Niemann-Pick type C, which accumulates cholesterol within cellular compartments. The research sheds light on the complex mechanism of cholesterol distribution and its role in maintaining optimal levels.
Alzheimer’s disease acquired from historic medical treatments
Researchers have identified five cases of Alzheimer's disease acquired through exposure to contaminated cadaver-derived human growth hormone (c-hGH) used in medical treatment between 1959 and 1985. Biomarker analyses and autopsy results confirmed the diagnoses, highlighting a rare but significant risk of transmission via this route.
Could two drugs be better than one for treating prostate cancer?
A Phase 3 clinical trial found that combining testosterone-blocking drugs prevents cancer spread and extends treatment time in patients with relapsed prostate cancer. The approach is more effective than single-drug treatment in delaying cancer progression.
Systemic changes induced by ASCOT in plasma proteome of women with impaired ovarian reserves
Researchers found that ASCOT reverses some age-related protein expression changes, enriching processes related to the complement cascade and immune system in patients with poor ovarian response. In contrast, patients with premature ovarian insufficiency showed enrichment in responses to oxygen-containing compounds and growth hormones.
A new versatile tool for studying fish hormones - may transform fish farming
A new versatile platform controls peptide hormones in fish, revealing surprising findings about conserved genetic networks and adaptable hormone regulation. This innovative method holds promise for transforming fish farming practices and exploring ways to prolong vertebrate lifespan.
Enlighten me
Researchers at Kyoto University discovered that liverwort Marchantia polymorpha uses gibberellin precursors to produce a signaling molecule aiding survival under shaded conditions. This metabolic pathway inheritance provides insight into the evolution of plant hormone responses.
Bonobos grow similarly to humans
Researchers found pronounced growth spurts in both body weight and length in bonobos, mirroring patterns seen in humans. The study's scale-corrected approach revealed similar hormone surges and corresponding growth curves in both species, highlighting a potential evolutionary connection.
Pusan National University researchers identify peptides for pollen tube growth in rice
The study reveals two OsRALF peptides essential for pollen tube germination and elongation, crucial for double fertilization. Exogenous application of these peptides enhances pollen tube elongation, while inhibiting germination at higher concentrations.
Unborn babies use ‘greedy’ gene from dads to ‘remote-control’ mums into feeding them extra food
Fetuses use a copy of a gene inherited from their dad to force their mum to release as much nutrients possible during pregnancy. This 'remote-control' system is operated by genes that can be switched on or off depending on whether they are a 'dad's' or 'mum's' gene.
Roots are capable of measuring heat on their own, new study shows
Plant roots detect temperature changes and adjust their growth accordingly. Researchers found that root cells produce more auxin in response to elevated temperatures, stimulating cell division and allowing roots to grow deeper into the soil. This discovery could help develop new approaches for plant breeding against climate change.
Investigating the intricacies of auxin signaling mechanisms in algae
Researchers discovered a TIR1/AFB-independent auxin signaling mechanism in Klebsormidium nitens, a primitive alga. They identified KnRAV as a key transcription factor that activates auxin-inducible genes and binds to promoter sequences.
The clue is in the glue - Nature’s secret for holding it together
A study by John Innes Centre researchers has revealed how plants avoid cracking under stress by using a growth hormone called brassinosteroid to loosen the straitjacket effect on their skin. The findings, published in Science, have implications for our understanding of plant development and potentially improve crop yields.
Self-esteem of kids with short stature tied to social supports, not height
A new study by Children's Hospital of Philadelphia found that the quality of life and self-esteem of children with short stature are associated with coping skills and social supports, rather than their height. The researchers suggest that addressing short stature through a broader, psychosocial approach might have a more positive impac...
Without this, plants cannot respond to temperature
Scientists at UC Riverside identify microRNA as a key player in plant temperature responses and growth, revealing its essential role in sensing environmental changes. The discovery has significant implications for increasing crop yields in diverse environments and adapting to climate change.
Pediatric Investigation review takes stock of history and current status of long-acting growth hormone therapy
Recent review article discusses clinical development in long-acting growth hormone (LAGH) therapy, which mimics natural GH release patterns. LAGH therapies reduce daily injection burden, improving patient compliance and treatment outcomes.
SMART researchers develop first nanotube sensors capable of detecting and distinguishing gibberellin plant hormones
Scientists have created a non-destructive method to detect and differentiate gibberellins, a class of plant hormones crucial for growth. The new nanosensors can identify changes in GA levels across various plant species, enabling early interventions against salinity stress.
Oncotarget | Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients
Researchers found that plasma GH levels are a potential biomarker for predicting treatment outcomes in patients with advanced HCC treated with Atezo/Bev. The study showed significantly superior overall survival and non-significant trend in favor of GH-low patients compared to GH-high patients.
Longevity treatments do not slow aging
Researchers tested three widely believed aging treatments in mice and found no impact on aging. A new analytical approach allowed them to measure aging processes more precisely, revealing that these treatments promote general health rather than targeting aging mechanisms.
Vitamin D supplementation, development among school-age children in an area with vitamin D deficiency
A randomized clinical trial of 8,800 school-age children with high vitamin D deficiency showed no impact on growth or pubertal development after 3 years of weekly oral vitamin D administration. Vitamin D deficiency is associated with stunting and obesity in children.
Study published in Endocrinology by Heritage College researchers finds disruption of the growth hormone receptor gene in adipose tissue results in increased lifespan in mice
Researchers discovered that stopping GH activity in fat cells improves health and increases lifespan in mice. The study found approximately 23% lifespan extension due to GHR disruption, with improved insulin sensitivity and reduced frailty scores.
The missing link: Fatty acid metabolism impacts plant immunity
A recent study by Zhenzhen Zhao and colleagues found that Arabidopsis plants lacking Acyl Carrier Protein 1 (ACP1) are more resistant to bacterial pathogen Pseudomonas syringae. ACP1 is essential for maintaining hormone homeostasis, which affects plant stress responses.
Transition milk improves health in neonatal calves
A new study published in the Journal of Dairy Science finds that feeding transition milk to neonatal Holstein calves instead of milk replacer improves health scores and stimulates intestinal development. The researchers found increased weight gain and improved gut health, with benefits seen in all sections of the small intestine.
Increase in leptin levels in preeclampsia prompts cardiovascular cascade that puts mother and baby at risk
Researchers discovered that midgestation leptin surge in preeclampsia leads to endothelial dysfunction, blood vessel constriction, and restricted fetal growth. This finding highlights the crucial role of leptin in pregnancy and its potential consequences on maternal and infant cardiovascular health.
Growth hormone improves liver health in people with nonalcoholic fatty liver disease
A new study found that growth hormone reduces liver fat and inflammation in patients with nonalcoholic fatty liver disease, improving liver function tests and markers of inflammation. The study showed significant improvements in liver health after administering growth hormone to 41 participants for 6 months.
Adult growth hormone deficiency increases medical costs, risk of additional health conditions
A study finds that adults with growth hormone deficiency (GHD) experience higher rates of endocrine and metabolic conditions, as well as cardiovascular disease. Daily somatropin injections improve quality of life, but treatment rates remain low.
Unlocked enzyme structure shows how strigolactone hormone controls plant growth
Researchers unlocked the structure of an enzyme that regulates plant growth in response to strigolactone hormone. The enzyme, MAX2, targets repressor proteins for destruction when it's unlocked, allowing genes to be expressed and activating various growth processes. This discovery sheds light on how plants adapt to their environment.
New potentially painkilling compound found in deep-water cone snails
Researchers discovered a new venom compound in deep-water cone snails, similar to the hormone somatostatin, with possible pharmaceutical applications for treating chronic pain and other human maladies. The study highlights the rich biochemical diversity of animal venoms and the need to explore new compounds.
Plant smoke detectors evolve as hormone sensors
Researchers have discovered an ancient receptor protein that can detect karrikins in smoke from burnt plant material, initiating molecular signals to speed up seed germination. The study also found that the receptors play a role in sensing growth hormones in plants, shedding light on the enigmatic karrikin signaling pathway.
Cedars-Sinai research shows that targeting growth hormone action with available drugs could lead to a new anti-aging therapeutic approach
Aging is associated with increased levels of local non-pituitary growth hormone in the colon, which contributes to epithelial damage. Targeting this growth hormone action with available drugs may lead to a novel anti-aging therapeutic strategy.
New app helps parents identify treatable childhood growth disorders earlier
A new mobile phone app called GrowthMonitor can accurately measure children's height and detect potential growth disorders, enabling early diagnosis and treatment. The app uses a traffic light system to inform parents of normal, amber, or red growth status, empowering them to take action.
In a gene tied to growth, scientists see glimmers of human history
Researchers have identified a shortened version of the human growth hormone receptor gene, GHRd3, which may help people survive in situations where resources are scarce or unpredictable. The study found that this variant emerged around 1-2 million years ago and was more prevalent in ancient humans and Neanderthals.