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Walking proteins need to rock and roll, new study finds

Kinesin proteins use a unique 'head-over-head' mechanism to propel themselves forward, allowing them to transport vital cargo through the cell. Researchers have discovered that this process is controlled by the breakdown of ATP and involves a rocking motion that allows kinesin to complete long-distance walks in a few seconds.

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Scientists figure out how cells' tiniest motors work

Researchers have figured out how kinesin motors separate chromosomes, distribute embryonic material, and transport precious cargo in organisms. The discovery reveals a crucial leapfrog motion that allows the motors to move along microtubules, generating force to haul objects up to a thousand times their own size.

Learning how cell's tiny motor powers its mobility

The discovery reveals how the kinesin motor generates motion along microtubule tracks, with a key role played by the neck linker. This understanding could lead to medical therapies targeting kinesin activity in cancer and neurodegenerative diseases.