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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Pigments, organelles persist in fossil feathers

Researchers have found evidence that melanosomes, which produce melanin pigment, are preserved in the fossil record of Anchiornis huxleyi, a bird-like dinosaur. The study uses electron microscopy and chemical analysis to demonstrate that the microbodies are indeed melanosomes, not microbes.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

New research unlocks a mystery of albinism

Scientists have discovered that a genetic mutation associated with type 2 oculocutaneous albinism blocks ion channels in melanosomes, leading to a lack of melanin production. The study provides new insights into the molecular mechanisms underlying albinism and may inspire new treatment ideas.

New UK study helps scientists understand melanoma development

A new UK study reveals that a genetic defect in the melanocortin1 receptor (MC1R) may make people more susceptible to developing melanoma. The study found that MC1R defects contribute to melanoma development by delaying DNA repair and increasing cancerous mutations.

Study finds linchpin of skin response to UVA light

A study published in the Proceedings of the National Academy of Sciences found that human melanocytes rely on the TRPA1 ion channel to detect UVA light and trigger the production of melanin. This discovery strengthens the evidence of a parallel between the skin's response to UVA light and the eye's detection of light.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Skin 'sees' UV light, starts producing pigment

Skin detects UVA radiation using a light-sensitive receptor found in eyes, leading to melanin production within hours. Researchers find that long-wavelength UVA light stimulates rhodopsin in melanocytes, triggering calcium signals and melanin accumulation.

Human skin begins tanning in seconds, and here's how

Researchers have discovered that human skin can begin tanning in seconds after exposure to UV light, using a mechanism similar to the retina's detection of light. This early response provides rapid protection against UV damage and may impact sunscreen design.

Melanin's 'trick' for maintaining radioprotection studied

Researchers discovered melanin can receive electrons, counteracting gamma radiation's oxidizing effects, resulting in electric current production. This finding has potential applications in the space industry, where equipment is exposed to high levels of radiation.

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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

No longer a gray area: Our hair bleaches itself as we grow older

A team of European scientists discovered that going gray is caused by a massive build-up of hydrogen peroxide, which blocks the normal synthesis of melanin, our hair's natural pigment. This research provides an important first step in understanding the root cause of gray hair.

Melanin production discovered in fat tissue

A two-year study found substantial quantities of melanin produced in morbidly obese patients' fat tissue, suggesting a natural defense mechanism against obesity-related conditions. The antioxidant properties of melanin may help suppress inflammatory properties of excess fat.

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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

New drug target in obesity: Fat cells make lots of melanin

Researchers found that fat cells in obese people produce melanin in excess, which could lead to the development of new treatments for obesity-related metabolic problems. The discovery was confirmed using additional laboratory tests and may provide a safer alternative to weight loss treatments.

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Blue-eyed humans have a single, common ancestor

A team at the University of Copenhagen discovered that people with blue eyes have a single common ancestor due to a genetic mutation in the OCA2 gene. This mutation resulted in reduced melanin production in the iris, effectively 'diluting' brown eyes to blue. Brown-eyed individuals exhibit more individual variation in their DNA.

What gives us sunburn protects crayfish against bacteria

A study published in Journal of Biological Chemistry reveals melanin's role in protecting freshwater crayfish from bacterial infections. Effective melanin production is crucial for the animals' survival against Aeromonas hydrophila.

Skin as a living coloring book

Scientists at Massachusetts General Hospital found that the Foxn1 gene determines where pigment is deposited in the epidermis and hair. The study reveals that melanocytes deliver melanin to specific cells indicated by the Foxn1 gene, which acts as a map for pigment distribution.

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Einstein researchers' discover 'radiation-eating' fungi

Researchers at Albert Einstein College of Medicine found fungi can harness ionizing radiation to produce food and spur growth, recalculating Earth's energy balance. This discovery could provide a sustainable food source for long-duration space missions or planetary colonization.

Scientists crack rhino horn riddle

A new study at Ohio University sheds light on the structural materials that form the horn's characteristic shape, explaining its curved tip. The team discovered dark patches made of calcium and melanin in the middle, which harden the core and protect it from sun damage.

Listening to the sound of skin cancer

Researchers have developed a new method to detect metastasizing melanoma cells in the blood using photoacoustic detection, which can identify as few as 10 cancer cells. The technique uses laser techniques and ultrasound methods to emit noise from cancer cells, allowing for early diagnosis and treatment.

Safer suntans through science

Scientists at the University of Kentucky are testing a lotion that stimulates melanin production, reducing UV damage and increasing skin protection. The treatment has promising results, offering an alternative to traditional sunless tanning products and tanning beds.

Skin cancer rare -- but more deadly -- in people with darker skin

A new study by the University of Cincinnati finds that dark-skinned individuals are at a higher risk of dying from skin cancer due to its aggressive nature and delayed diagnosis. Despite having lower incidence rates, dark-skinned people are more likely to die from skin cancer, highlighting the need for increased awareness and preventio...

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New studies show topical glucosamine targets pigment overproduction

Researchers used a non-invasive imaging system to detect pigment changes and test the efficacy of topical N-acetyl glucosamine in reducing hyperpigmentation. The study found that N-acetyl glucosamine was more effective than placebo and, when combined with niacinamide, showed significant reductions in facial hyperpigmented spots.

The unfolding of amyloid's true colors

The study reveals that Pme117, a glycoprotein involved in melanosomes, rapidly folds into functional amyloid fibers that enhance melanin production. This discovery suggests that amyloid formation may serve a physiological role in cells, contradicting current views on pathogenic amyloids.

RPE meets EPR

Scientists have found that melanin, a pigment in the body, acts as a sponge to absorb and destroy free radicals that damage retinal cells. This discovery offers hope for preventing macular degeneration, a leading cause of blindness.

Melanin makes skin vulnerable to harmful ultraviolet rays

Research finds that melanin in hair follicles can increase cell death in response to UV radiation, depending on its color. The study used mice with engineered pigmentation to demonstrate this effect, suggesting that people with darker skin may not be as vulnerable to skin cancer as those with fair skin.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.