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Pigments, organelles persist in fossil feathers

Researchers have found evidence that melanosomes, which produce melanin pigment, are preserved in the fossil record of Anchiornis huxleyi, a bird-like dinosaur. The study uses electron microscopy and chemical analysis to demonstrate that the microbodies are indeed melanosomes, not microbes.

SourceBrown University·JournalScientific Reports·DateAug 27, 2015

New research unlocks a mystery of albinism

Scientists have discovered that a genetic mutation associated with type 2 oculocutaneous albinism blocks ion channels in melanosomes, leading to a lack of melanin production. The study provides new insights into the molecular mechanisms underlying albinism and may inspire new treatment ideas.

Study finds linchpin of skin response to UVA light

A study published in the Proceedings of the National Academy of Sciences found that human melanocytes rely on the TRPA1 ion channel to detect UVA light and trigger the production of melanin. This discovery strengthens the evidence of a parallel between the skin's response to UVA light and the eye's detection of light.

SourceBrown University·JournalProceedings of the National Academy of Sciences·DateJan 21, 2013

New findings by GW researcher break tanning misconceptions: 'There is no such thing as a safe tan'

A GW School of Medicine and Health Sciences study published in Nature Communications reveals that traditional sun protection may not be effective against skin cancer. The research found that UVA radiation induces melanin formation, which is directly involved in melanoma formation, contradicting the notion of a 'safe tan'.

SourceGeorge Washington University·JournalNature Communications·DateJul 23, 2012

Blue-eyed humans have a single, common ancestor

A team at the University of Copenhagen discovered that people with blue eyes have a single common ancestor due to a genetic mutation in the OCA2 gene. This mutation resulted in reduced melanin production in the iris, effectively 'diluting' brown eyes to blue. Brown-eyed individuals exhibit more individual variation in their DNA.

SourceUniversity of Copenhagen·JournalHuman Genetics·DateJan 30, 2008

Skin as a living coloring book

Scientists at Massachusetts General Hospital found that the Foxn1 gene determines where pigment is deposited in the epidermis and hair. The study reveals that melanocytes deliver melanin to specific cells indicated by the Foxn1 gene, which acts as a map for pigment distribution.

Scientists crack rhino horn riddle

A new study at Ohio University sheds light on the structural materials that form the horn's characteristic shape, explaining its curved tip. The team discovered dark patches made of calcium and melanin in the middle, which harden the core and protect it from sun damage.

SourceOhio University·JournalJournal of Morphology·DateNov 6, 2006

Listening to the sound of skin cancer

Researchers have developed a new method to detect metastasizing melanoma cells in the blood using photoacoustic detection, which can identify as few as 10 cancer cells. The technique uses laser techniques and ultrasound methods to emit noise from cancer cells, allowing for early diagnosis and treatment.

SourceOptica·JournalOptics Letters·DateOct 16, 2006

Safer suntans through science

Scientists at the University of Kentucky are testing a lotion that stimulates melanin production, reducing UV damage and increasing skin protection. The treatment has promising results, offering an alternative to traditional sunless tanning products and tanning beds.

SourceUniversity of Kentucky·JournalNature·DateSep 26, 2006

The unfolding of amyloid's true colors

The study reveals that Pme117, a glycoprotein involved in melanosomes, rapidly folds into functional amyloid fibers that enhance melanin production. This discovery suggests that amyloid formation may serve a physiological role in cells, contradicting current views on pathogenic amyloids.

SourcePLOS·JournalPLOS Biology·DateNov 28, 2005

RPE meets EPR

Scientists have found that melanin, a pigment in the body, acts as a sponge to absorb and destroy free radicals that damage retinal cells. This discovery offers hope for preventing macular degeneration, a leading cause of blindness.

SourceUniversity of Chicago Medical Center·JournalJournal of the American Chemical Society·DateJul 28, 2005

Melanin makes skin vulnerable to harmful ultraviolet rays

Research finds that melanin in hair follicles can increase cell death in response to UV radiation, depending on its color. The study used mice with engineered pigmentation to demonstrate this effect, suggesting that people with darker skin may not be as vulnerable to skin cancer as those with fair skin.

SourceYale University·JournalProceedings of the National Academy of Sciences·DateOct 13, 2004