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Up to one-third of antibody drugs are nonspecific, study shows

A study published in mAbs reveals that up to one-third of antibody-based drugs exhibit nonspecific binding to unintended targets, a serious concern for patient safety. The Membrane Proteome Array technology helped identify this issue, challenging the long-held belief in absolute antibody specificity.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Biophysicists unravel secrets of genetic switch

Researchers discovered how nonspecific binding plays a critical role in controlling the switch between dormant and virulent states in bacteria. The study used single-molecule techniques to characterize the role of non-specific binding in facilitating the closure of a DNA loop that switches off virulence.