Articles tagged with Rrna Synthesis
Researchers discovered a long, non-coding RNA called PAPAS that regulates rRNA production in epithelial cells. A high PAPAS level reduces tumour growth and metastases in breast cancer, while its suppression promotes carcinogenesis. The findings suggest potential diagnostic and therapeutic applications for RNA therapy.
Researchers at TTUHSC are studying a new approach to inhibit STAT3, a protein associated with 70% of human tumors. Disrupting STAT3 synthesis on ribosomes could lead to new cancer treatments.
Researchers used a yeast model to understand the dynamics of early-stage ribosomal subunit assembly, discovering snR190 functions as an RNA chaperone. The study also identified Dbp7 as the enzyme responsible for dissociating snR190 from ribosomal RNA precursors.
Scientists have successfully synthesized ribosomes from scratch using a novel technology that mimics the natural process. This breakthrough enables the creation of functional ribosomes with exotic functions and could lead to the discovery of new antibiotics and modified protein-generators.
A Scripps Research Institute scientist has discovered a molecular switch controlling protein synthesis in ribosomes, which could lead to potential treatments for cancer and other diseases. The study suggests that regulating this process may help prevent disease states such as Alzheimer's and diabetes.