Articles tagged with Scaffold Proteins
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Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have developed a new method to generate bone tissue using the body's own stem cells, which could replace traditional bone grafting techniques. The process, known as biodegradable polymer scaffolding material and BMP, has been successful in lab experiments and shows promise for future clinical trials.
Researchers discovered a unique protein bond that enables NMDA receptors to stabilize on the cell surface, increasing communication between brain cells. The scaffolding protein SAP102 binds with GluN2B at two sites, facilitating receptor turnover and preventing debilitating diseases like Alzheimer's and Parkinson's.
Researchers at the University of California - San Diego discovered a structural basis for how strep protein can trigger toxic shock. The proteins form dense scaffolds that mimic blood clots, leading to widespread inflammation and organ failure. This breakthrough provides new insights into the pathogenesis of strep-induced toxic shock.
Concordia University researchers have made a breakthrough in converting plant material into biofuels using engineered bacteria. By introducing structural proteins on the surface of Lactococcus lactis, scientists can create a stable surface for chemical activity, paving the way for more efficient bioprocessing and organic material break...
The MDC researchers have discovered a crucial scaffold regulating the identification and disposal of defective proteins. The study reveals that the flexible Usa1 subunit tethers specific modules of the enzyme complex, connecting them to form a larger complex to degrade insoluble membrane proteins.
IGC scientists, led by Lars Jansen, discover protein CENP-N that triggers centromere assembly, providing new insights into accurate cell division. The discovery earns an EMBO installation grant and a paper in Nature Cell Biology.
Researchers at the Salk Institute found that stable proteins within the nucleus's control structures can become damaged with age, leading to impaired function and contributing to cellular aging. This discovery provides new insights into the aging process and may lead to novel approaches for treating neurodegenerative diseases.
Researchers at MIT's Picower Institute for Learning and Memory report that a missing brain protein may be one of the culprits behind autism and other brain disorders. They found that an enzyme called Cdk5 plays a critical role in recruiting key scaffolding proteins to develop synapses.
A University of Utah study suggests that proteins serve as anchors, holding other proteins in place to strengthen synapses and contribute to forming and retaining memories. The research is relevant not only to how memory and learning work but also to Alzheimer's disease, which involves a breakdown in protein movement within synapses.
UCSF researchers identified PSD-95 protein as key link between nerve cells, suggesting possible target for treating mental retardation and nerve damage. The protein stimulates maturation of synapses, enabling brain development, learning, and memory.
A study by Ohio State University researchers has found that microtubules harbor important proteins the cells need for signaling, gene expression and cell division. This link could provide clinicians with important potential targets for new drugs against diverse diseases like cancer, heart disease and certain inflammatory ailments.
Researchers at Harvard Medical School have identified a key pathway linking the growth cone's membrane receptor to actin, the final agent of change. The study reveals an uninterrupted chain of signaling events that enables neurons to transmit information from the membrane to the cytoskeleton.
Researchers discovered a novel family of cell surface proteins that regulate nerve cell connections by inducing synapse formation. The Neuroligin/b-Neurexin junction is the core of this process, forming a transsynaptic cell-adhesion complex that initiates protein-protein-interaction cascades.
Researchers have identified a protein in viper venom that blocks the spread of tumors in laboratory mice. The study may lead to the development of new cancer-fighting drugs. Scientists are now working on understanding the molecular structure of the protein, eristostatin, which could help unlock its potential as a therapeutic agent.
A recent study at the University of Illinois found that polyethylene glycol (PEG) coating can undergo attractive interactions with proteins, changing its configuration and potentially increasing biocompatibility. The discovery has significant implications for biomedical applications, such as implants and artificial scaffolds.