Transmembrane Receptors | Topics

Articles tagged with Transmembrane Receptors

Novel therapeutic strategy against melanoma: combined targeting of hedgehog signaling and BRD4

Researchers propose targeting non-canonical HH/GLI signaling to improve response rate and durability of therapeutic effects exerted by SMO inhibition in melanoma. The findings suggest that combined targeting of hedgehog signaling and BRD4 could provide a novel therapeutic option against melanoma.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Researchers discover new insight into a common signaling pathway

Researchers have determined that the conformation of Smad3 protein regulates TGF-ß pathway interaction with other proteins, affecting signal transduction and gene expression. This discovery provides new insight into molecular mechanisms of TGF-ß signaling and potential targets for drug design.