Articles tagged with Viral Rna
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Biomedical engineers have developed a new probe that allows visualization of single RNA molecules within live cells, enabling scientists to study RNA's operation and interaction with binding proteins. The tool overcomes issues with fluorescent probes, allowing for hours-long imaging and distinguishing between targeted and unbound probes.
A study by researchers at the University of Illinois reveals that RIG-I, a cellular protein, can detect viral RNA and trigger an immune response in every cell type. The protein uses two major parts to distinguish between viral and self-RNA, using a unique 'triphosphate' tag.
Researchers developed a hairpin-shaped molecule that imitates the spatial structure of an important viral protein, preventing the discharge of viral RNA from the cell nucleus. This breakthrough could lead to the development of a new class of HIV treatment drugs.
A Bowling Green State University biologist believes long-dormant influenza strains can be unleashed by melting ice in remote global outposts, posing a potential threat to human immunity.
A novel mechanism of dengue virus replication has been discovered, involving the circularization of its genome. This process allows the viral RNA polymerase to interact with a distant site on the genome, initiating replication. The study's findings suggest a widespread strategy for viral RNA replication.
Researchers found surprising parallels in RNA virus replication, suggesting a common strategy to kill various viruses. The discovery could lead to more general virus control strategies.
Researchers found that ribavirin increases the mutation rate of RNA viruses, pushing them into genetic meltdown and making them useless. This mechanism offers hope for designing more effective antiviral drugs.
Researchers at Penn State have discovered a new mechanism for an existing antiviral drug that can alter the genetic makeup of RNA viruses. The discovery uses ribavirin to change the structure of viral RNA, preventing the virus from producing faithful copies and ultimately leading to its collapse.
A comprehensive study of HIV patients taking protease inhibitors found that marijuana use did not alter viral loads, with subjects who smoked or took oral dronabinol experiencing slightly greater declines in HIV RNA levels than those taking placebos. Adverse effects were minimal and not statistically significant.
Researchers at UCSF have discovered a region in the telomerase enzyme that could be targeted to kill cancer cells and regenerate damaged cells. The discovery provides new insights into the mechanism of telomerase and its potential as a therapeutic target, as well as its role in regulating cell life span.
A Purdue University study reveals that a virus uses six RNAs to create a motor that transports DNA, facilitating the development of nanoscale devices. The research also improves scientists' understanding of how cells transport large molecules through membranes.
Scientists have determined the 3D molecular structure of HIV's nucleocapsid protein, which recognizes and binds to viral RNA. This discovery may lead to the development of highly specific anti-AIDS drugs that can prevent HIV spread and be safe for patients.
Researchers successfully infect chimpanzees with a defined HCV sequence, identifying essential elements for infection and paving the way for the development of better treatments. The availability of this infectious sequence will enable precise studies of HCV replication and inform the creation of effective vaccines or immunotherapies.
A team of scientists led by Jennifer Doudna solved the 3D structure of a large portion of an RNA enzyme, revealing its ability to trigger cell activity and potentially provide the first method for genetic reproduction. This breakthrough could help design new drugs to fight lethal viruses and repair genetic errors.
A team of US researchers has cracked the three-dimensional atomic structure of a large RNA molecule, achieved after four years of research. The new image shows the densely packed and highly organized double-helix-shaped regions of the molecule, with magnesium ions providing 'glue' for its organization.