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Exploring how pheromones drive mating behavior in mice

Scientists investigated the role of ancient VR type-1 (ancV1R) receptor in pheromone detection using knockout mice. The study found that ancV1R-deficient female mice had impaired pheromone detection and exhibited abnormal sexual behavior.

SourceInstitute of Science Tokyo·JournalCurrent Biology·TypeExperimental study·DateDec 19, 2024

EphA2 signaling in eye lens aging: wild-type, knockout, and aging mice

Researchers from Indiana University have uncovered how the EphA2 protein receptor contributes to cataract formation. The study found that canonical ligand-dependent EphA2 signaling remains stable in aging lens tissue, while non-canonical signaling increases with age, affecting lens fiber cell maturation.

SourceImpact Journals LLC·JournalAging-US·TypeNews article·DateNov 13, 2024