Articles tagged with Keratinocytes
A study published in The FASEB Journal has identified specific physiological properties that regulate melanocyte function, offering hope for new treatments of pigmentation disorders. Keratinocytes are found to influence pigment production and help regulate skin coloration.
Researchers found that keratinocytes can control melanocyte pigmentation by producing chemical signals, leading to new possibilities for bioengineered skin grafts and cosmetics. This discovery has significant implications for individuals with medical conditions requiring skin transplants or pigment diseases.
A study published in JCI Journals reveals that vitamin D3 production is induced by skin wounds, leading to increased expression of antimicrobial peptides and microbial recognition receptors. This mechanism helps protect the skin from harmful microbes and enhances immune response.
Researchers at Scripps Research Institute have discovered TRPV3, a protein that detects warm temperatures through skin cells, not sensory neurons. The receptor is activated by both thermal heat and the compound camphor, leading to new insights into pain sensation and potential drug targets.
Researchers at the University of Bonn have found a new effective therapy for psoriasis by blocking the division of epidermis cells. The treatment, which uses metalloproteinase inhibitors, has shown no toxic side effects and may provide a promising solution for the condition.
Researchers at Scripps Research Institute have identified the first temperature-sensing molecule found in keratinocytes, the major type of cell in the skin, which can detect warm and hot temperatures above 33°C. This discovery opens up new possibilities for pain therapeutics.
Researchers identify PPARbeta as a key gene regulator in the cellular response to inflammation and wound healing. The protein is crucial for keratinocyte differentiation and migration, enabling effective wound healing.