Researchers have discovered an organelle in a prokaryotic bacterium that is identical to the acidocalcisome found in eukaryotes. The finding suggests a targeted approach to killing disease-causing organisms and challenges the origin of eukaryotic organelles.
A study by University of Illinois researchers has identified a mechanism that determines whether pigment moves within cells. The discovery reveals that the motor protein is disengaged as a result of phosphorylation during cell division. If confirmed, this finding could lead to new cancer treatments targeting specific mechanisms.
The study demonstrates a fundamental role of caveolin-1 and caveolae in organizing multiple signalling pathways in the cell. The absence of caveolae impaired nitric oxide and calcium signaling, leading to severe physical limitations in caveolin-1-disrupted mice.