Pseudopods | Topics | BrightSurf

New study decodes one of the living world’s fastest cell movements

Researchers at Okayama University discovered genes and proteins responsible for the rapid contraction of axopodia in Heliozoa, a group of eukaryotes. The study identified key players in microtubule disruption, including katanin p60, kinesin, and calcium signaling proteins.

SourceOkayama University·JournalJournal of Eukaryotic Microbiology·TypeExperimental study·DateJan 18, 2023

Molecular inhibition gets cells on the move

A team of researchers at Osaka University has identified the molecular mechanism that enables cells to move in a specific direction. By analyzing the interaction between PTEN and PIP3 molecules, they found that these molecules mutually suppress each other, preventing cells from forming pseudopodia at different ends.

SourceOsaka University·JournalNature Communications·DateNov 8, 2018

Sculpting a cell's backside

Researchers discovered a new protein, Callipygian, which aids in cell migration by shutting off proteins at the front edge of cells. The protein helps create the back of a cell, allowing it to move directionally.

SourceJohns Hopkins Medicine·JournalProceedings of the National Academy of Sciences·DateJul 7, 2015