Articles tagged with Reticulocytes
A new cell line from human adult bone marrow can grow infinitely and differentiate into red blood cells, making it a potential source for generating endless amounts of RBCs. This breakthrough could simplify methods for establishing immortalized cell lines and select clones with maximum RBC production potential.
Researchers at the University of Bristol have established a new model system using red blood cells grown in the laboratory to study malaria parasite invasion. They used CRISPR-Cas9 to edit the genome of immature cells, removing a protein critical for invasion and showing that reticulocytes generated from this edited line were completel...
A new study identifies 360 proteins in human reticulocyte exosomes that may work as a vaccine against vivax malaria. The findings support further studies on using reticulocyte exosomes and HuRex as a potential vaccine delivery platform.
A team of SUTD researchers identified over 1800 proteins in young reticulocytes, revealing key changes in protein composition during maturation. These findings provide insights into the transition from a multi-lobular to biconcave shape and increased deformability.
A new study published in PLOS Pathogens reveals that malaria parasites growing in different host cells can develop resistance to antimalarial drugs. Researchers found that the metabolic state of red blood cells provides a unique environment for Plasmodium parasites, allowing them to scavenge essential resources and evade drug targeting.