Articles tagged with Single Neurons
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers discovered cerebellar signals strengthen visual cues during learning, facilitating precise visuomotor associations. This finding highlights the cerebellum's crucial role in cognitive functions beyond motor control.
The Neuropixels Ultra probe overcomes technical challenges in recording individual cells across multiple brain regions. It detects twice as many brain cells and distinguishes specific subtypes, enabling scientists to decode and track brain cell performance related to visual stimuli.
Researchers at Linköping University developed a miniaturized iontronic micropipette to precisely modulate neuronal and astrocytic activity. The study revealed dynamic dynamics between cells, highlighting the importance of chemical signaling in brain function.
Scientists found that parts of human chromosomes have evolved rapidly to enable complex brain development in humans. However, this acceleration may also lead to neurodevelopmental disorders like autism. The study used artificial neurons derived from human and chimpanzee cell lines.
Tobias Ackels' research reveals that mammals can differentiate between odor sources at lightning speed, using a temporal dimension to orient themselves in space. This ability is encoded in the output of the olfactory bulb and could be used for early detection of dementia.
A new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START) has been developed to map the brain's intricate neuronal connections. The technique combines two advanced technologies to resolve cortical connectivity at the resolution of transcriptomic cell types, enabling the identification of distinct p...
Researchers created an ultra-small vision implant with single-neuron sized electrodes, allowing for thousands of 'pixels' to be stimulated simultaneously. The implant's unique combination of flexible materials ensures long-term functionality and stability.
Researchers at Janelia Research Campus have released Kilosort4, an updated version of the popular spike-sorting software that requires less manual work and is more accurate. The new software improves processing and allows for easier use, making it indispensable for neuroscientists worldwide.
Researchers have discovered that specific neurons in the thalamus are actively involved in processing cardiac and respiratory signals. This breakthrough understanding of brain-body integration may help characterize how subcortical regions process signals through a functional pathway from internal organs.
Researchers developed a new machine learning method to analyze brain data, separating intrinsic neural patterns from sensory inputs. The method revealed surprisingly consistent hidden patterns in three subjects' neural activity despite different tasks.
Researchers discovered that a specific phase of neck motor neuron activation in roundworms adjusts their trajectory toward higher salt concentrations. This finding highlights the neural mechanisms underlying navigation and sensory-motor integration, shedding light on how even simple animals adapt to environmental changes.
Researchers at UCSF found a feedback loop between immune protein IL-31 and nerve cells, which dials back nearby inflammation and promotes skin healing. This discovery could lead to new treatments for conditions like eczema, allergies, and asthma by targeting the nervous system's role in regulating the immune response.
A study published in Science reveals that ganglia in the neck region are responsible for disrupting melatonin production and causing sleep disturbances in people with heart conditions. Researchers found that macrophages accumulate in the ganglion, leading to inflammation and scarring, which can be treated with drugs.
Researchers at TUM developed a new approach to measure human brain activity using microelectrodes and awake brain surgery. They found individual neurons specialize in handling specific numbers, providing insights into cognitive functions and developing solutions for brain function disorders.
A new study from Duke University finds that single neurons in the visual cortex rapidly switch between reporting on two separate objects by alternating signals. When objects overlap, brain cells treat them as a single entity, suggesting a more complex encoding process for everyday perception.
Researchers found that despite a powerful brain response to sound during sleep, the level of alpha-beta waves associated with attention and expectation is significantly reduced. This means the brain can analyze auditory input but fails to focus on it, resulting in no conscious awareness.
Researchers discovered two novel categories of cells in the BLA that respond to ethological stimuli, including event-specific neurons responding to one type of stimulus and panresponsive neurons responding equally well to multiple stimuli. These findings suggest a larger role for the BLA in memory and behavior.
A new study suggests that supplementing a diet with Ascidiacea, also known as sea squirts, reverses some main signs of aging in animal models. The researchers found that plasmalogens, vital to body processes, decrease with age and contribute to neurodegenerative diseases like Alzheimer's and Parkinson's.
A study by Tokyo University of Science researchers has demonstrated that a computationally-light model can simulate complex brain cell responses, including periodic and quasi-periodic responses. The Izhikevich neuron model was found to be capable of reproducing both types of responses at lower computational cost.
Scientists reconstructed a whole-brain projectome comprising over 6,000 single neurons in the mouse prefrontal cortex, revealing 64 projectome-defined neuron subtypes. The study utilized software package Fast Neurite Tracer to analyze TB-sized imaging data and construct high-resolution intra-PFC networks.
Researchers at Boston University have developed optoacoustic neurostimulation with single neuron and subcellular level precision. Optoacoustic neuromodulation may offer advantages over ultrasonic neuromodulation, including higher spatial temporal resolution.
Researchers at Max Planck Institute for Biological Intelligence discovered how a specific type of neuron can multiply two incoming signals in fruit flies. This finding provides insight into the algebra of neurons, which underlies various brain processes such as sound localization and visual motion detection.
Researchers found that distributed codes among larger populations of neurons in the prefrontal cortex make information more reliable and robust. This discovery could support advanced cognitive abilities and potentially treat disorders of memory and cognition.
Biomedical engineers found that individual neurons fire in seconds-long, coordinated cascades during rest, triggering activity across the brain. This organized pattern of activity may be linked to arousal and memory systems, with implications for understanding cognitive decline and Alzheimer's disease.
Researchers at The Hebrew University of Jerusalem have developed a new deep learning artificial infrastructure inspired by individual neurons. Their approach uses complex mathematical modeling to replicate the brain's electrical processes and create more intelligent AI systems.
Researchers develop coloring technique to 'paint' neurons with fluorescent colors, enabling identification of each neuron in an animal's nervous system. The NeuroPAL method allows scientists to record a whole nervous system in action and decode brainwide activity patterns.
Researchers validated a popular method using RNA sequencing to identify unknown human brain neurons by comparing it with crab nervous system data. The study could contribute to future breakthroughs in understanding the brain and neurological diseases.
Researchers from Istituto Italiano di Tecnologia, University of Salento, and Harvard Medical School have developed a new light-based method to capture and pinpoint the epicenter of neural activity. The approach allows for novel ways to map connections across different brain regions.
A WVU researcher recorded single neurons in epilepsy patients to study the pre-supplementary motor area's role in visual search tasks. The study found that 40% of neurons signaled target detection, regardless of task format or cue.
Scientists at the University of Bonn and Amsterdam created a novel human nerve cell model consisting of a single nerve cell from pluripotent stem cells, providing highly standardized conditions for investigating nerve cell functions. The model was tested with various stimulation experiments and demonstrated highly reproducible data.
Researchers confirm that the human brain and monkeys perceive the Pinna-Brelstaff figure's rotating rings similarly, with a delay of around 15 milliseconds. This finding supports Jan Purkinje's theory that illusions contain visual truth and sheds light on how our brains handle perception vs reality.
Researchers from Duke University found that single neurons can switch between encoding information for two different sounds, suggesting a potential explanation for how the brain processes complex information. The study's results may also shed light on perceptual and cognitive limitations.
A new study by neuroscientists at Duke University found that even practiced movements are imperfect due to brain noise, which can affect our responding movements. The research team discovered a correlation between the activity of individual neurons and the size of eye movement delays.
A Scripps Research Institute scientist has been awarded $2 million to investigate the impact of aging on a unique type of nerve cell involved in memory. The study aims to understand how gene expression changes with age and may lead to the development of novel therapeutics for age-related diseases.
Researchers at Lund University have developed implantable electrodes that capture signals from single neurons without causing brain tissue damage. The electrodes, called 3-D electrodes, are extremely soft and flexible, enabling stable recordings over long periods.
Researchers have developed a new theoretical model to understand how cells monitor and self-regulate their properties in the face of continual cellular turnover. The model suggests that neurons use an internal gauge to adjust ion channel expression, but this system can lead to neuronal hyperexcitability and disrupt overall homeostasis.
Researchers at Scripps Florida Institute discovered significant changes in gene expression and neural circuitry as neurons age, shedding light on cognitive decline and potential therapeutic targets. The study, using the marine snail Aplysia californica, highlights the complex interplay between aging and neuron communication.
Researchers at University of Michigan discover that a single gene, DLK, regulates both axon and dendrite growth in neurons. The finding highlights the importance of considering the bimodal nature of neurons when developing new treatments for regeneration of nerve cells.
Researchers have found that individuals can rapidly and voluntarily control neurons deep in their brains, allowing them to manipulate images on computer screens. The study uses epilepsy patients with electrodes implanted in their brains to record individual neuron activity in response to specific images.
Researchers at University College London found that single neurons and even individual dendrites can effectively distinguish between different temporal sequences of incoming information. This challenges the widely held view that large numbers of neurons working together are necessary for sequence processing in the brain.
Researchers used pictures, spoken and written names to show that single neurons in the human hippocampus and surrounding areas respond selectively to representations of the same individual using different sensory prompts. This process enables abstraction and recognition of highly variable images.
A Hebrew U study has shown that humans can detect finer frequency differences than animals, using single neuron recordings in the auditory cortex. This suggests a unique neural representation of frequency in the human brain.
Studies have mapped brain regions and feeding cycles, but this study records neuronal activity across a full cycle of hunger-satiety-hunger. The researchers found that populations of neurons change their activity over the different phases of a feeding cycle, reflecting the physiological state of the animals.
A team of researchers has discovered a neural mechanism related to impulsive decision-making in pigeons. The study found that single neurons in the avian forebrain show increased activity when anticipating rewards, with activation levels decreasing as delays increase, leading to preferences for immediate over delayed rewards. This brea...
Researchers at Johns Hopkins University found that brain cells 'synchronize' to pay attention to a single stream of sensory information. This synchronization, like singing in a chorus, enables the brain to filter out distractions and prioritize important stimuli.
Scientists discover Munc13-1 regulates the readily releasable pool of synaptic vesicles, leading to a functional shutdown of synapses. Without Munc13-1, nerve cells cannot signal due to an arrest in vesicle maturation, highlighting its essential role in neurotransmitter release.