Articles tagged with Sperm
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A new study found that physically active men have better semen parameters and hormone values than sedentary men. The study assessed 31 male participants and found significant differences in semen volume, sperm count, and hormone levels between physically active and sedentary groups.
A recent study has uncovered two genetic deletions that are responsible for severely low sperm count, accounting for 8% of cases. The most common deletion increased the risk by a factor of 2, while the rare b2/b4 deletion doubled the risk and accounted for 6% of cases.
A large-scale analysis of Y chromosomes found two spontaneously recurring deletions responsible for approximately 8% of failed sperm production. The deletion known as b2/b4 increases the risk of severe spermatogenic failure and is associated with roughly 6% of cases.
Researchers have discovered a key protein, RABL2, that affects sperm tail length and motility, potentially leading to new avenues for male infertility treatment. A mutation in this protein can result in significantly shorter sperm tails and decreased production.
A new species of freshwater fish, Gambusia quadruncus, has been discovered in east-central Mexico with distinctive male genitalia and colorful female anal spots. These characteristics may play a role in mating control and success, offering insights into reproductive strategies in aquatic species.
Researchers found that eggs that don't fertilise due to defective PLCz protein can be treated with human PLCz, initiating fertilisation and improving pregnancy chances. The study strengthens potential use of PLCz in treating male infertility.
Researchers at Cold Spring Harbor Laboratory discovered that small RNAs guide epigenetic modifications of DNA in plants, allowing for inherited traits and influencing cross-breeding practices. This finding has important implications for agriculture and crop selection.
Researchers have discovered a novel mechanism in pollen cells that silences potentially mutagenic sequences of mobile DNA, thereby avoiding damage to new plants. The mechanism involves the addition of methyl groups to DNA sequences, which is restored by small RNA molecules, ensuring epigenetic inheritance.
A study by Berkeley Lab scientists found that older men who consume more vitamin C, E, folate, and zinc have less sperm DNA damage. This suggests that adequate micronutrient intake can help counteract the detrimental effects of aging on sperm genome health.
A new direction in research for male contraceptives has been identified using the small molecule JQ1, which blocks chromatin remodeling necessary for sperm production. Studies show that mice treated with JQ1 have lower sperm counts and reduced sperm motility, paving the way for potential development of a male contraceptive pill.
Researchers at Dana-Farber Cancer Institute and Baylor College of Medicine developed a small molecule compound, JQ1, that generates reversible birth control in male mice by disrupting spermatogenesis. The study showed a decrease in sperm count and quality without affecting testosterone production or offspring health.
Researchers have discovered a compound that reversibly infertile men without affecting their sex drive, using the small molecule to target fertility proteins. The new form of birth control works by reducing sperm count and motility, making it an effective and novel strategy for male contraception.
A study published in Biology of Reproduction found that consuming 75 grams of walnuts per day enhances sperm vitality, motility, and morphology in healthy young men. The walnut diet also reduced chromosomal abnormalities in sperm.
Researchers from Instituto Gulbenkian de Ciência describe the steps involved in making a motile flagellum in fruit fly sperm cells. The process involves the formation of a critical protein structure called the central microtubule pair, essential for coordinated movement.
A new study by Syracuse University scientists found that slower and/or longer sperm outcompete their faster rivals in fruit fly reproduction. The research, published in Current Biology, used genetically altered fruit flies to observe sperm in real-time inside the female reproductive tract.
Researchers sequenced 91 human sperm from one man, revealing the whole-genome sequence and degree of genetic mixing, with implications for studying cancer, infertility, and other disorders. The study provides a detailed view of recombination in individual sperm, allowing for diagnosis and detection of potential problems.
Researchers have developed a new technology that allows for an individualized map of the DNA within a single sperm cell, providing insights into genetic diversity and potential applications in reproductive disorders. This technology could also be used to characterize differences in cancer cells taken from patients.
A study led by Dr. Christina Wang at LA BioMed has shown a new male contraceptive gel containing testosterone and Nestorone to sharply lower sperm counts in men, achieving low sperm concentrations in 88-89% of participants. The results warrant further study as a safe and effective hormonal male contraceptive.
Researchers at Tufts University found that female fireflies prefer males with larger nuptial gifts after mating, leading to higher reproductive success. This discovery challenges the conventional view that flash duration is the primary cue for female choice in firefly courtship.
A new study presents a promising reversible male contraceptive method using a combination of testosterone and Nestorone gels. The study found that 88-89% of men using the gel experienced very low sperm counts, and complete absence of sperm occurred in significantly more men compared to those using testosterone alone.
A recent study published in Human Reproduction found that many common lifestyle choices, including smoking and alcohol consumption, have little effect on male fertility. Instead, factors such as ethnicity, occupation, and previous conception history may play a greater role in determining sperm quality.
A new type of male contraceptive could be created by regulating the Katnal1 gene, which controls sperm maturation and development. This finding offers an alternative to hormone-disrupting treatments that can cause side effects.
A new type of male contraceptive may be developed thanks to a key gene essential for sperm development, Katnal1. The gene regulates microtubules that support and provide nutrients to developing sperm cells.
A new study has identified a gene expression fingerprint associated with low sperm fertilizing capacity, predicting male infertility. The research used RNA profiling to analyze semen samples from 68 donors and found significant differences in gene expression between fertile and infertile individuals.
Researchers at Brown University have discovered how flowers achieve industrial precision in pollination. The team found that flowers use a safeguard system to prevent too many pollen tubes from delivering too many sperm, and that fertilization can be salvaged if the first sperm is ineffective.
Scientists have shed new light on sperm navigation in the female reproductive tract, finding they crawl along walls and collide frequently. This research provides fresh insight into how sperm find their way to the egg, potentially informing future innovation in fertility treatments.
Insect glands produce secretions that help sperm survive and guide fertilization in fruit flies, potentially providing clues to similar human reproductive glands. Mutant fruit flies with absent glands are infertile, but expression of a mouse gene can partially restore gland formation.
Researchers found that male pseudoscorpions treated with tetracycline suffered reduced sperm viability and passed this toxic effect on their untreated sons. This transgenerational effect has significant implications for human health and food animal production.
Researchers at Durham University have identified a key gene involved in sperm-to-egg binding, enabling fertilization in mammals. The discovery highlights the importance of cumulus cells surrounding eggs and suggests potential avenues for improving IVF treatment effectiveness and developing new contraceptives.
Researchers have devised a new method for producing genetically modified animals using haploid embryonic stem cells, which may enable genetic modification of animals that can't be modified by today's means. The technique could also potentially be used in assisted human reproduction for those affected by genetic disease.
Researchers at the University of Nevada, Reno found that antibiotic tetracycline reduces sperm viability in male pseudoscorpions and passes this effect to their sons. The study suggests a similar impact on humans and other species may occur.
A study of eight male giant pandas found that reproductive fitness varies throughout the year, with waves of activity occurring 3-5 months before most females display estrus. This new understanding will help improve captive panda management and potentially aid in reintroducing pandas into the wild.
Researchers discovered that ovastacin, an astacin family member, cleaves the ZP2 protein in the zona pellucida matrix surrounding eggs. This proteolysis blocks additional sperm binding, preventing polyspermy and ensuring embryonic development. Ovastacin's function is crucial for single fertilization.
A team led by Ralph Brinster at the University of Pennsylvania School of Veterinary Medicine has successfully preserved spermatogonial stem cells in mice for over a decade, demonstrating their viability and ability to produce healthy offspring. The study provides promising evidence for a potential fertility treatment in humans, address...
Researchers found that giant squids' large eyes are better suited for spotting large objects, like whales, rather than average prey. Their 10-inch eyes allow them to see predators from a distance despite the dim light of their underwater habitat.
Researchers found that giant squids' large eyes collect more light, improving their ability to detect small contrast differences and bioluminescence. The boost in detecting low-light differences is critical for spotting approaching sperm whales, but the squid's escape is not entirely dependent on its eye size.
A study of 99 men found an association between high total fat intake and lower total sperm count and concentration. Men who consumed more omega-3 polyunsaturated fats had better formed sperm than those who consumed less.
Researchers discovered that sperm only react to changes in calcium concentration, not the concentration itself, allowing them to maneuver even in high calcium environments. This calculation enables sperm to follow chemical gradients and navigate towards eggs.
Researchers from the Caesar Research Centre in Bonn have discovered that sperm do not function like olfactory cells and cannot detect smells. The 'Lily of the Valley phenomenon', which suggested a role for scents in fertilization, is now considered a laboratory artefact.
Researchers at Yale University have identified a new regulator that controls p53's activity in sperm production, which could lead to breakthroughs in fertility treatments and cancer therapy. The study found that a molecule called Pumilo 1 plays a crucial role in this process.
Studies of diving beetles reveal that sperm form follows female reproductive organ function, challenging the paradigm of post-mating sexual selection. Researchers found diverse sperm shapes and structures adapted to navigate complex female reproductive tracts, suggesting females can drive evolutionary changes in male traits.
Researchers have confirmed that therapeutic ultrasound can be used as a male contraceptive, providing up to 2.5 months of protection in rats with two 15-minute sessions. The method was initially overlooked for decades due to concerns over its effectiveness, but new evidence suggests it may offer an alternative to existing options.
New research uses commercially available therapeutic ultrasound equipment to reduce sperm counts in male rats, resulting in infertility. The non-invasive treatment reduced sperm reserves far below levels seen in fertile men.
Research by Monash University reveals that producing high-quality sperm comes with significant health costs for males. The study found a negative correlation between sperm quality and immune function, suggesting males invest energy strategically to produce better sperm.
Researchers at the University of Illinois discovered that docosahexaenoic acid (DHA) is crucial for constructing the acrosome, a critical structure in fertilization. Without DHA, sperm cells fail to form properly and fertility is compromised.
A study published in Environmental Health Perspectives found that men with higher levels of DDE and PCBs had significantly higher rates of sperm abnormalities. Researchers used a new sperm imaging methodology to detect chromosomal abnormalities, highlighting the potential impact of environmental exposure on male fertility.
Research published in the Journal of Leukocyte Biology suggests that high levels of estradiol prior to ovulation weaken the immune system, increasing susceptibility to infection. This natural dip in immunity may allow spermatozoa to survive and fertilize an egg successfully.
Research on naked mole rat sperm reveals a lack of competition among breeding males, resulting in degenerate evolution. The sperm's motility and structure are abnormal for any other mammal, but the males are still fertile and father healthy offspring.
A recent study published in Developmental Cell suggests that the reach of parental control in embryonic development may be longer than thought. The research found evidence that genetic marks from sperm can be passed on to embryos, influencing gene expression later in development.
Ben-Gurion University researchers have made a significant breakthrough in male fertility, producing normal sperm from mouse cells. The study, published in Asian Journal of Andrology, outlines the generation of spermatozoa from mouse testicular germ cells under in vitro culture using a three-dimensional Soft Agar Culture System.
A team of NYU biologists uncovered a previously unknown role for female reproductive tract cells in fruit flies, which affects sperm movement and fertility. The discovery may provide insights into manipulating reproductive behavior in other insects.
A study by San Francisco State University researchers has identified critical fertility enzymes in nematode worms, shedding light on sperm development and mobility. These PP1 phosphatases play a key role in separating chromosomes during division and propelling the sperm with a unique treadmilling motion.
Biologists at Florida State University devise novel method to replicate cell motility in vitro using worm sperm, revealing unprecedented insight into cell crawling mechanisms. This breakthrough has significant implications for understanding human health and developing therapies to combat cancer.
A new study by Brown University toxicologists found that male mice exposed to high doses of BPA during pregnancy showed no signs of harm to their testes as adults. The researchers suggest that the mother's metabolism may detoxify much of the BPA, reducing exposure to the fetus.
A study from UNC Chapel Hill School of Medicine has illuminated a critical step in demethylation, giving stem cell researchers information to reprogram adult cells. The disappearance of chemical tags is a passive process, not catalyzed by an enzyme.
In a study published in Science, researchers found that female promiscuity can increase genetic benefits in inbred populations. Females who mate with multiple males produce more viable offspring, while those who only mate with one male experience reduced reproductive success.
Scientists identify uroguanylin as a potential target for controlling appetite and obesity. They also found a link between Parkinson disease and fat levels in the blood, with implications for treating this neurodegenerative disorder.
Researchers have identified the key sugar molecule SLeX on the outer coat of human eggs that enables them to capture sperm. This discovery has significant implications for understanding fertility and developing new treatments for infertility and sub-fertility.
Research found that small 'sneaker' males produce larger sperm than large, competing males. This adaptation allows them to increase their chances of fertilizing female eggs.
A new study reveals that female mosquitoes cannot detect the fertility status of their mates, making it difficult to control mosquito populations and prevent the spread of malaria. Researchers found that females will mate with both fertile and spermless males, leading to a loss of reproductive opportunities.