A computational model of the more than 26 million atoms in a DNA-packed viral capsid has expanded our understanding of virus structure and DNA dynamics. The study found that the DNA formed switchback loops as it was pushed into the capsid, similar to how DNA is organized in eukaryotic cells.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalNature·TypeComputational simulation/modeling·DateMar 6, 2024
Researchers at UCSF used clinical data and a precision medicine approach to identify early risk factors for Alzheimer’s disease, predicting its onset with 72% accuracy. High cholesterol, osteoporosis, and erectile dysfunction were found to be predictive factors in both men and women.
SourceUniversity of California - San Francisco·JournalNature Aging·DateFeb 21, 2024
Researchers have introduced an optimization technique that accelerates Bayesian inference without requiring extensive user effort. This new automated method achieves more accurate results faster than another popular approach and offers reliable uncertainty estimates to help scientists understand when to trust their predictions.
SourceMassachusetts Institute of Technology·JournalJournal of Machine Learning Research·DateFeb 21, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A recent study from Argonne National Laboratory has uncovered new insights into the relationship between genetic ancestry and prostate cancer risk. The research, which included large increases in representation among men of African, Hispanic, and Asian ancestries, found 187 new genetic markers that provide more accuracy in calculating ...
SourceDOE/Argonne National Laboratory·JournalNature·DateFeb 13, 2024
A Bayesian model analysis reveals how key covariates affect SARS-CoV-2 viral kinetics at individual and population levels. The study identifies intrinsic differences between Omicron and Delta variants, shedding light on their growth drivers.
SourcePLOS·JournalPLOS Biology·TypeComputational simulation/modeling·DateJan 30, 2024
A new study reveals that Singapore has lost 37% of its species over the past two centuries, with larger mammals and forest-dependent birds being particularly at risk. The researchers recommend prioritizing landscape-scale conservation efforts for charismatic species, such as tigers and orangutans, to mitigate extinction rates.
SourceNational University of Singapore·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateJan 29, 2024
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A European study links agricultural activities with West Nile virus emergence and spread, as well as urbanization and migratory bird patterns. The study highlights the need for enhanced surveillance in Central Europe.
SourcePLOS·JournalPLOS Pathogens·TypeComputational simulation/modeling·DateJan 25, 2024
A new model developed by MIT engineers predicts how certain shoe properties will affect a runner's performance, incorporating factors like stiffness and springiness. The model aims to help designers create high-performing shoes with novel properties.
SourceMassachusetts Institute of Technology·JournalJournal of Biomechanical Engineering·DateJan 24, 2024
A new study by Northwestern University found that lab-trained AI models are easily misled by tissue contaminants, resulting in errors in diagnoses and vessel damage detection. The researchers suggest improving the problem of quantifying and addressing biological impurities in AI models to enhance accuracy.
SourceNorthwestern University·JournalModern Pathology·DateJan 23, 2024
A research group from Tohoku University Graduate School of Engineering has replicated human-like variable speed walking using a musculoskeletal model steered by a reflex control method reflective of the human nervous system. The breakthrough in biomechanics and robotics sets a new benchmark in understanding human movement.
SourceTohoku University·JournalPLOS Computational Biology·DateJan 22, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study published in Palaeontologia Electronica shows the Megalodon was more slender than earlier studies suggested, changing our understanding of its behavior and impact on ancient ocean life. The revised model suggests a longer digestive canal, potentially leading to less predation pressure on other marine creatures.
SourceUniversity of California - Riverside·JournalPalaeontologia Electronica·DateJan 21, 2024
Researchers used the 2022 FIFA World Cup to study COVID-19 spread and hospitalizations at mass gatherings. They found that pre-travel screenings did little to prevent infections, but pre-match testing with rapid antigen or reverse transcription polymerase chain reaction tests was more effective.
SourceYork University·JournalPLOS Computational Biology·DateJan 18, 2024
The review discusses the optical aspects of QPAT, including mathematical models for light propagation and interaction with biological tissues. The authors outline two approaches to estimating chromophore concentrations from absorbed optical energy density data, highlighting the challenges associated with practical implementation, such ...
SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateJan 11, 2024
A study predicts tecovirimat administration impacts time to viral clearance in mpox patients, combining pre-clinical and clinical data. Early tecovirimat treatment shortens the time to mpox clearance in a human infection model.
SourcePLOS·JournalPLOS Biology·TypeComputational simulation/modeling·DateDec 21, 2023
Multiple sclerosis affects over 2.8 million worldwide, and EU funding will investigate viral infections like EBV as potential causes and co-factors. The BEHIND-MS consortium aims to develop new cell models to test hypotheses on the disease's development.
SourceEuropean Multiple Sclerosis Platform·DateDec 7, 2023
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers developed a new framework to predict how microbes interact with each other in unique compositions. Most microbes had minimal impact on the final outcome, with only select few playing crucial roles. The model has potential applications in personalized medicine and understanding microbiome assembly.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateNov 30, 2023
Researchers found that a more complex climate model projects stronger and sustained carbon uptake by plants until the end of the 21st century. This could lead to a larger impact on mitigating climate change through nature-based solutions like reforestation.
SourceTrinity College Dublin·JournalScience Advances·DateNov 17, 2023
Researchers at Purdue University developed a new tool to visualize neural network decisions, making it easier to identify errors in image recognition. The tool uses graph-topological data analysis to provide a bird's-eye view of all images in a database, revealing areas where the network struggles to distinguish between classifications.
SourcePurdue University·JournalNature Machine Intelligence·TypeData/statistical analysis·DateNov 16, 2023
Researchers at Tufts University developed a genome-scale metabolic model to identify potential new treatment targets for Lyme disease. The model successfully predicted two compounds that selectively target Lyme bacteria while leaving other helpful bacteria untouched.
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A recent study discovered two subgroups of people with idiopathic generalized epilepsy, one experiencing highest incidence during sleep and the other during daytime. The researchers found that either dynamics of cortisol or sleep stage transition explained most of the observed distributions of epileptiform discharges.
SourceUniversity of Birmingham·JournalPLOS Computational Biology·TypeData/statistical analysis·DateOct 17, 2023
A new model describes microswimmer self-propulsion energy requirements, enabling optimized shape designs and applications in microfluidics, biophysics, and material science. The study reveals surprising similarities between artificial and natural shapes.
SourceMax Planck Institute for Dynamics and Self-Organization·JournalNature Communications·TypeComputational simulation/modeling·DateOct 12, 2023
Researchers at Linköping University developed an AI-based method applicable to various medical and biological issues, accurately estimating people's chronological age and determining smoking status. The models identify previously known epigenetic markers used in other models, but also new markers associated with conditions.
SourceLinköping University·JournalBriefings in Bioinformatics·TypeComputational simulation/modeling·DateOct 11, 2023
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Cilia synchronize their beating pattern by leveraging the fluid surrounding them and the border region. This observation reveals that border regions play a critical role in self-organization of living matter, similar to macroscopic mechanisms.
SourceMax Planck Institute for Dynamics and Self-Organization·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateSep 29, 2023
A recent study published in Radiology: Artificial Intelligence found significant racial and sex-related biases in an AI chest X-ray foundation model, affecting its performance across patient subgroups. The researchers highlighted the need for comprehensive bias analysis to ensure diversity and representativeness in dataset collection.
SourceRadiological Society of North America·JournalRadiology Artificial Intelligence·DateSep 27, 2023
Insilico Medicine has identified 9 potential dual-purpose targets against aging and 14 major age-related diseases using Microsoft BioGPT. The proposed genes include CCR5 and PTH, which have not been previously correlated to the aging process.
Veterinary researchers used 3D organoids to investigate lung cancer in dogs, finding that canine primary lung cancer organoids faithfully mirrored tumor tissues. The study identified correlations between organoid cell viability and specific target molecules, paving the way for personalized treatment approaches.
SourceTokyo University of Agriculture and Technology·JournalBiomedicine & Pharmacotherapy·DateSep 26, 2023
A new Michigan State University and Corewell Health research found that in-home prenatal services can significantly reduce the risk of premature births and infant deaths. Pregnant individuals receiving enhanced prenatal care saw a 57% reduced risk, while expectant Black mothers experienced an even greater reduction.
SourceCorewell Health·JournalJAMA Pediatrics·DateSep 25, 2023
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Scientists developed computational eye models to help patients and surgeons select ideal intraocular lenses and predict visual outcomes. The technology uses anatomical information of the patient's eye to provide guidance on expected optical quality post-operatively.
SourceUniversity of Rochester·JournalJournal of Cataract & Refractive Surgery·TypeMeta-analysis·DateSep 21, 2023
Associate Professor Tadashi Ando from Tokyo University of Science conducted a study to test the performance of OPC and OPC3 water models, evaluating their shear viscosities and comparing values to experimental calculations. The calculated viscosities for both models were very close, with notable accuracy at temperatures above 310 K.
SourceTokyo University of Science·JournalThe Journal of Chemical Physics·TypeComputational simulation/modeling·DateSep 21, 2023
The UMass Amherst-UT Austin team has been awarded $27.5 million by the CDC to establish the nation's first disease outbreak response and modeling network. The $250 million program will support decision makers during public health emergencies like COVID-19.
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
The CDC has awarded a coalition led by UC San Diego researchers $17.5 million to develop innovative tools and networks for rapid response to emerging disease outbreaks. The project aims to integrate forecasting and analytic approaches with data to inform public health decisions.
By 2070, 44.61% of koala habitats in Australia will be highly susceptible to bushfires, up from 39.56% today. Koalas may struggle to survive due to habitat fragmentation and food source vulnerability.
SourceFlinders University·JournalEnvironmental Technology & Innovation·TypeComputational simulation/modeling·DateSep 18, 2023
The collaboration has garnered $5.68 million of grant support, with a five-year $2.13 million National Institutes of Health R01 grant and a five-year $2.89 million NIH R01 grant. Researchers are using computational biology to model a key Alzheimer's protein called TREM2 and its interactions with small chemical molecules.
Researchers analyzed data from the Global Biodiversity Information Facility and found a universal pattern of species abundance distributions, with most species being rare but not extremely rare. The study's findings may help answer Darwin's question about why some species are common while others are rare.
SourceGerman Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig·JournalNature Ecology & Evolution·TypeData/statistical analysis·DateSep 4, 2023
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A team of researchers at the University of Waterloo and Dalhousie University have developed a method for forecasting short-term disease progression using limited data. The Sparsity and Delay Embedding-based Forecasting model, or SPADE4, uses machine learning to predict epidemic progressions with high accuracy.
SourceUniversity of Waterloo·JournalBulletin of Mathematical Biology·DateAug 31, 2023
A new study by the University of Oldenburg team confirms that radio waves in the VHF range above 116MHz have no impact on migratory birds' magnetic compass sense. This discovery debunks previous theories suggesting mobile communication networks affect the birds' navigation.
SourceUniversity of Oldenburg·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateAug 28, 2023
A new study found that voluntary collective isolation alone was ineffective in preventing the spread of COVID-19 among the Amazonian Tsimané. The researchers used a computer model and serological testing to confirm their predictions, showing nearly identical infection rates across communities.
SourceUniversity of Utah·JournalPLOS Biology·TypeComputational simulation/modeling·DateAug 24, 2023
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers at City of Hope have identified new molecular targets on a cell receptor that play a major role in cardiovascular regulation. The findings could lead to improved drugs for heart disease, an unfortunate side effect of some cancer therapies.
SourceCity of Hope·JournalScience Signaling·TypeExperimental study·DateAug 14, 2023
Researchers from Osaka University have shed light on how certain proteins contribute to the formation of piRNAs, a type of RNA that protects the genome. Tejas plays a key role in recruiting Vas and Spn-E, facilitating nuage formation and piRNA processing.
SourceOsaka University·JournalJournal of Cell Biology·TypeExperimental study·DateAug 9, 2023
Researchers found that clinical strains of Aspergillus fumigatus differ significantly from environmental strains in amino acid synthesis. The fungus appears to shape the lung microbiome to its advantage, surviving on vital metabolites produced by other microorganisms.
SourceLeibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute -·JournalNature Communications·TypeComputational simulation/modeling·DateAug 7, 2023
A team of scientists has successfully elucidated the structure and function of LITE-1, a biomolecule used by Caenorhabditis elegans to detect danger. The researchers used artificial intelligence to predict the structure of LITE-1, which is a channel protein that forms a pore in the cell membrane allowing charged particles to pass through.
SourceGoethe University Frankfurt·JournalCurrent Biology·TypeExperimental study·DateAug 2, 2023
Researchers have identified KIAA0930 as a key factor causing muscle atrophy in cancer cells, which could lead to the development of new anti-cachexia therapies. The study found that KIAA0930 knockdown cells showed increased muscle mass and weight compared to control cells.
SourceImpact Journals LLC·JournalOncotarget·TypeObservational study·DateJul 26, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
GOBI overcomes model-free and model-based inference method limitations by introducing an easily testable condition for a general monotonic ODE model to reproduce time-series data. It successfully infers positive and negative regulations in various networks, distinguishing between direct and indirect causation.
SourceInstitute for Basic Science·JournalNature Communications·TypeMeta-analysis·DateJul 24, 2023
A study by Kyoto University found that Daphnia's phenotypic plasticity is strongly related to its body size and the type of predator. Medium-sized Daphnia are more vulnerable to predation by both Chaoborus larvae and fish, which prefer larger prey.
SourceKyoto University·JournalFreshwater Biology·TypeMeta-analysis·DateJul 19, 2023
The Save Our Seas Foundation's World of Sharks website now features interactive 3D models of white sharks and manta rays, enabling users to explore shark physiology and evolution in an engaging way. The 3D models are open-access and free to view and download for non-profit use.
SourceSave Our Seas Foundation·TypeComputational simulation/modeling·DateJul 13, 2023
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A recent study led by McGill University estimates that the European Union will face significant economic losses due to biological invasions, with costs projected to reach over €142.73 billion by 2040. The study highlights the need for effective management and collaboration to address this threat.
SourceMcGill University·JournalEnvironmental Sciences Europe·TypeComputational simulation/modeling·DateJul 13, 2023
A team of researchers from Kyoto University and international institutions has developed a mathematical solution to the temporal asymmetry of nonequilibrium disordered Ising networks. This breakthrough offers insights into the behavior of biological systems, machine learning, and AI tools.
SourceKyoto University·JournalNature Communications·TypeComputational simulation/modeling·DateJul 4, 2023
Researchers have developed a new technique to generically treat several kinds of cancer, showing tumors grew almost three times less and survival rates reached 100% after just one injection. The method targets cancer cells with alpha radiation, sparing healthy tissue.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers, led by Elizabeth King, aim to develop a knowledge base on complex genetic traits using fruit fly models. The project seeks to address the scientific knowledge gap in this field by focusing on interconnectedness among multiple factors.
Biomedical engineers at UTS have developed an intervertebral disc-on-a-chip, a precision-engineered toolbox for low back pain studies. The device simulates the complex mechanobiology of native tissue, enabling accurate evaluation of experimental methods for treatment or regeneration.
SourceUniversity of Technology Sydney·JournalTrends in Biotechnology·TypeComputational simulation/modeling·DateMay 28, 2023
Researchers designed and tested textile fibers that can change shape and generate force like a muscle, showing promise for use as cell scaffolds. The findings suggest the fibers could be used to develop 3D models of living, moving systems in the human body.
SourceNorth Carolina State University·JournalBiomimetics·DateMay 25, 2023
Porphyrinic metal-organic frameworks (PMOFs) have been synthesized using various methods, including solvothermal synthesis. The native biocompatible properties of porphyrins endow PMOFs with great potential in biological applications. Several possible frameworks can be formed with a large scale of metal ions.
SourceBeijing Zhongke Journal Publising Co. Ltd.·JournalAdvanced Sensor and Energy Materials·DateMay 14, 2023
A new model for disease transmission takes into account the effects of social dynamics and social norms on behaviors such as mask-wearing. The study found that small changes in certain factors can lead to large changes in disease spread rates, creating distinct infection waves. Social conformity creates a 'stickiness' where individuals...
SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateMay 10, 2023
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers have developed a new method called EvoAug that uses artificial DNA sequences inspired by evolution to train deep neural networks for genome analysis. This approach enables the model to recognize regulatory motifs more accurately, leading to better performance and potential breakthroughs in understanding human health.
SourceCold Spring Harbor Laboratory·JournalGenome Biology·DateMay 4, 2023
Researchers developed machine-learning algorithms to generate proteins with specific structural features, enabling the creation of biologically inspired materials. The models can produce millions of new protein ideas in a few days, allowing scientists to explore unique applications.
SourceMassachusetts Institute of Technology·JournalChem·DateApr 20, 2023
A new computational model suggests that reducing hormone doses in contraceptives could effectively suppress ovulation. The model found that hormone doses could be lowered by up to 92% in estrogen-only contraceptives and 43% in progesterone-only contraceptives, while still preventing ovulation.
SourcePLOS·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateApr 13, 2023
A team of researchers at Eötvös Loránd University developed a general formula to calculate honest equilibrium in any model, independent of signal costs. Their results reveal that honesty does not require signal costs to be paid in equilibrium, and that the cost is borne by cheaters, not honest individuals.
SourceEötvös Loránd University·JournalBMC Biology·DateApr 4, 2023
Researchers found that fish in large schools are more willing to take risks and tune down their sensitivity to social cues, reducing the likelihood of responding to false alarms. This dynamic adjustment allows individuals to maintain control over their behavior, suggesting a potential evolutionary advantage in coping with misinformation.
SourceCornell University·JournalProceedings of the National Academy of Sciences·DateMar 28, 2023
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
ISB researchers constructed a biological body mass index that offers a more accurate representation of metabolic health. The team found that even with no weight loss, individuals can be getting healthier biologically through positive lifestyle changes.
SourceInstitute for Systems Biology·JournalNature Medicine·TypeComputational simulation/modeling·DateMar 20, 2023
Researchers from Japan create a new model for estimating transepidermal water loss, providing a more realistic picture of skin water loss. The new method uses confocal laser microscopy and Raman spectroscopy to measure stratum corneum thickness and water content.
SourceOkayama University·JournalAdvanced Biomedical Engineering·TypeExperimental study·DateMar 20, 2023