Teratogens

Forever chemicals affect the genes of unhatched ducklings

Researchers discover that PFAS can harm ducklings even before they hatch, altering their gene expression and potentially affecting their fat metabolism and immune system. The findings support demands for a blanket EU ban on the substances, which are considered 'forever chemicals' due to their long-term persistence in the environment.

SourceNorwegian University of Science and Technology·JournalEnvironmental Toxicology and Chemistry·TypeExperimental study·DateNov 11, 2025

Common medications may affect brain development through unexpected cholesterol disruption

Researchers have discovered that commonly prescribed medications can disrupt sterol biosynthesis in developing brains, potentially affecting neural development and function. The study highlights the need for reevaluating medication safety during pregnancy and early childhood.

SourceGenomic Press·JournalBrain Medicine·TypeLiterature review·DateFeb 25, 2025

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Fish reveal cause of altered human facial development

Researchers tested five chemicals on zebrafish embryos and found that all caused impaired migration of bone-forming cells, leading to facial malformation. The study suggests a potential general mechanism underlying teratogenic chemicals and proposes using zebrafish as an alternative method for testing cross-species teratogens.

SourceUniversity of Tokyo·JournalToxicological Sciences·TypeExperimental study·DateSep 28, 2023

ASHG honors Jan M. Friedman with Arno Motulsky-Barton Childs Award

Jan M. Friedman, a Professor of Medical Genetics at the University of British Columbia, is receiving the Arno Motulsky-Barton Childs Award for his exceptional contributions to human genetics education globally. He has produced influential work on clinical genetics education and has led efforts to increase its presence in medical schools.

SourceAmerican Society of Human Genetics·DateJul 18, 2018