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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Do people and monkeys see colors the same way?

Researchers discovered that a certain short-wave or blue sensitive cone circuit is absent in marmosets and differs from the macaque monkey's circuit. This finding suggests that humans have unique neural wiring for color vision that may be linked to recent evolutionary adaptations.

Study suggests catalyst for human brain evolution

Large structural changes in human ancestors' genomes may have sparked smaller changes that set human brains apart from other primates. Researchers found that many enhancers, which regulate brain development, are located near these regions, suggesting a link between DNA folding and brain evolution.

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How evolution has influenced the shape of the brain

A MedUni Vienna study examining the connection between brain structure and function found that brain shape evolved parallel to its capabilities. The research analyzed 90 species of Euarchontoglires, revealing clusters of growth patterns linked to cognitive abilities.

An embarrassment of riches

Researchers found that Indigenous populations with limited food availability have slower brain aging, while industrialized populations experience faster cognitive decline. Beyond a certain point, excessive energy gain from food intake is associated with smaller brain volumes and faster aging.

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For clues to healthy brain aging, look to the Bolivian Amazon

Researchers found that Tsimané and Mosetén adults experienced less brain atrophy and improved cardiovascular health compared to industrialized populations. These findings suggest an optimal lifestyle balance between daily exertion and food abundance may be key to healthy brain aging.

Parental investment may have aided evolution of larger brains

A review of evidence suggests that increased parental energy investment in young offspring may have facilitated the evolution of larger brains in some species. This is particularly true for warm-blooded species, which tend to invest more energy in their young through actions such as egg production and lactation.

Ohio University researchers help reveal evolution of oldest spinosaur brains

Researchers from Ohio University and the University of Southampton reconstructed the brains and inner ears of two British spinosaurs to gain insight into their interaction with their environment. They found that the olfactory bulbs were not particularly developed and the ear was attuned to low-frequency sounds.

Highly social mammals live longer than solitary species

A study by Chinese Academy of Sciences researchers found that group-living mammals live longer than solitary ones, with a 100-fold variation in longevity among species. The team identified 31 genes and pathways linked to both social organization and lifespan.

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Evolution of uniquely human DNA was a balancing act, study concludes

Researchers found that many changes to human DNA had opposing effects, with some variants making enhancers stronger while others made them weaker. This discovery has implications for understanding human evolution and the potential link between human DNA variations and psychiatric diseases.

525-million-year-old fossil defies textbook explanation for brain evolution

A new study on a 525-million-year-old fossil has shed light on the origin and composition of arthropod heads, resolving a century-old debate. The discovery of a delicately preserved nervous system in the fossil of Cardiodictyon catenulum, a tiny sea creature, suggests that the brain and trunk nervous system evolved separately.

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UTA study: Brain evolution is linked to competition

Trinidadian killifish exhibit larger brain size in high-competition environments, increasing their ability to forage and survive. The study provides experimental evidence that brain size is an adaptive trait in dense populations.

Scientists unearth another brain-shrinking mammal

A new study reveals that European moles reduce their brains by 11% in winter and regrow them by 4% in summer to conserve energy. This phenomenon, known as Dehnel's phenomenon, is driven by cold conditions rather than food shortage alone.

The gene to which we owe our big brain

Researchers produced human and chimpanzee brain organoids to investigate the role of ARHGAP11B in brain evolution. The study found that the gene is essential for neocortex development, with its absence or inhibition leading to decreased levels of critical brain stem cells.

Dragons and brain evolution

A team of scientists generated a molecular atlas of the Australian bearded dragon's brain, comparing it to mouse data. The findings suggest that both reptilian and mammalian brains evolved clade-specific neuron types from a common ancestral set, challenging popular views on brain evolution.

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UNLV research: No, the human brain did not shrink 3,000 years ago

A team of UNLV-led researchers questions the hypothesis that modern humans experienced an evolutionary decrease in brain size during the transition to complex societies. They analyzed a dataset of early human fossil and museum specimens, finding no reduction in brain size over 30,000 years.

A look inside ancient fish heads

A study comparing ancient lungfish fossils to modern brain structures reveals the evolutionary history of these ancient fish. The research suggests that lungfish relied on their sense of smell to navigate environments, unlike other fish that use sight more powerfully.

Connectivity of language areas unique in the human brain

Researchers discovered that humans have expanded connectivity of language areas compared to chimpanzees, with new connections to frontal and parietal lobes. The study suggests that these unique connections may be crucial for human language abilities.

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New insights into the complexity of the brain

A recent study out of the Complexity Science Hub Vienna developed a mathematical and computational framework for analysing neural activity in C. elegans, a tiny worm used to study neural activity. The study proposes a way to unmask the roles of neurons by using more natural perturbations.

Bat brains organized for echolocation and flight

Researchers at UC Davis and UC Berkeley have mapped the full motor cortex of Egyptian fruit bats, showing that brain areas represent common synergies of muscles rather than individual muscles. This study highlights the unique motor control abilities of these bats, which use their tongue to echolocate and aim sonar beams.

Scientists see signs of traumatic brain injury in headbutting muskox

Researchers found signs of concussions and head trauma in the brains of deceased headbutting muskoxen and bighorn sheep. The study provides insights into human injuries and opens the possibility that studying these animals could help researchers understand and reduce traumatic brain injuries.

Ubiquitous nutrients suppress appetite and promote movement

A study published in Current Biology found that consuming non-essential amino acids can curb appetite and encourage physical activity in mice. This mechanism is thought to be rooted in evolutionary history, where eating these amino acids promoted the urge to seek out more nutrient-rich food sources.

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Neuron counts reveal brain complexity evolution in land vertebrates

A comprehensive analysis of brain cellular composition across amniotes shows that mammals and birds have dramatically increased neuron numbers in the telencephalon and cerebellum, associated with higher cognition. The study suggests that only a handful of unique evolutionary events augmented brain processing power in these groups.

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New technique provides insights into the evolution of the brain

A research team identified H3 acetylation as a crucial factor in human brain development, leading to the unique neocortex structure. This finding could pave the way for new treatments for neurodegenerative diseases by manipulating basal progenitor cell proliferation.

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New fossils show what the ancestral brains of arthropods looked like

Rare fossils from the Cambrian period confirm the presence of an ancestral frontal domain in arthropods, which gives rise to crucial neural centers involved in decision-making and memory. The discovery also sheds new light on the evolutionary origin of visual systems in arthropods.

Near-death experiences, a survival strategy ?

A recent study suggests that near-death experiences (NDEs) in humans may be linked to evolutionary mechanisms, specifically thanatosis - the phenomenon of death-feigning or tonic immobility. This defense mechanism is thought to have arisen as a survival strategy in animals and has been preserved across various species, including humans.

Mammals evolved big brains after big disasters

The study reveals complex patterns in brain-body scaling, with many large-brained species having low relative brain sizes due to selective pressures. The authors conclude that the evolution of intelligence cannot be solely measured by brain size.

How birds evolved big brains

Researchers found that birds and non-avian dinosaurs had similar brain sizes before the mass extinction, but after, some bird families evolved large-brained birds by shrinking body size. Parrots and corvids, including crows, showed exceptional cognitive capacity and rapid brain evolution.

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Origins of human language pathway in the brain at least 25 million years old

Researchers have found a precursor to the human language pathway in living primates, illuminating an earlier evolutionary origin of at least 25 million years. The study reveals a segment of the language pathway that interconnects the auditory cortex with frontal lobe regions, important for processing speech and language.

Lucy had an ape-like brain

A three-million-year-old brain imprint reveals that Australopithecus afarensis infants may have relied on caregivers for a prolonged period. The study found no evidence of human-like brain reorganization, but suggested protracted brain growth similar to modern humans.

Skull scans reveal evolutionary secrets of fossil brains

A new study published in Science Advances used CT-scanning technology to view fossil skulls of Australopithecus afarensis and shed light on the evolution of brain organization and growth. The research reveals that while Lucy's species had an ape-like brain structure, the brain took longer to reach adult size.

New study reveals early evolution of cortex

Researchers at Karolinska Institutet have discovered a detailed blueprint for the development of the human cortex in the ancient lamprey brain, shifting its origin to over 500 million years ago.

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The brain does not follow the head

Researchers found that human brains evolved independently of changes to the braincase, despite both being affected by bipedalism. The study used CT and MRI data to quantify spatial relationships between brain structures and cranial structures.

Evolution designed by parasites

Research by Marco Del Giudice reveals parasites manipulate host behavior to increase transmission chances and alter neural functioning. Hosts evolve countermeasures to evade manipulation, but these adaptations may also create new vulnerabilities.

Guidelines for managing severe traumatic brain injury continue to evolve

The guidelines for managing severe traumatic brain injury continue to evolve as new evidence emerges, emphasizing the need for high-quality research and clinically applicable recommendations. Key challenges and goals for the future include generating more robust evidence and translating it into effective patient care.

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Genetic factors influence human brain expansion

A recent study published in JNeurosci analyzed brain scans from over 600 children and adolescents, revealing genetically-mediated associations between brain region size and intelligence. The research suggests that evolutionary expansion of the human brain is largely under genetic control.

Slow but steady: New study sheds light on the brain evolution of turtles

A new study on turtle brain evolution reveals that their brains have changed slowly and constantly over 210 million years, with modern turtles showing a wide variety of brain shapes and sizes. The first turtles with fully formed shells were likely living on land, contradicting previous hypotheses about their origins.

Modern human brain organization emerged only recently

Researchers found that the modern human brain shape developed gradually within the species, with fossils showing a transition from elongated to globular shapes between 100,000 and 35,000 years ago. This evolution was independent of brain size and was accompanied by changes in early brain development.

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CLOCK gene may hold answers to human brain evolution

A new study provides insight into the CLOCK gene's vital role in regulating human-specific genes important to brain evolution. The findings suggest that CLOCK regulates genes linked to cognitive disorders and has an important role in human neuronal migration, a process crucial for brain development.

Dinosaur evolution: Lumbering giants had agile ancestors

Researchers discovered that early sauropod dinosaurs like Saturnalia tupiniquim were capable of a bipedal gait and had agile ancestors. The brain structure of S. tupiniquim revealed specific features enabling it to track moving objects with its eyes, execute rapid movements of its head and neck in a coordinated fashion.

UA researchers: Brains evolved to need exercise

Researchers propose adaptive capacity model to understand exercise-brain connection, suggesting physical activity impacts brain structure and function from evolutionary history as hunter-gatherers. Exercise may enhance cognitive abilities and prevent age-related decline or neurodegenerative diseases like Alzheimer's.

Changes in Early Stone Age tool production have 'musical' ties

Researchers found that Acheulian tools required integration of visual working memory, auditory information, and complex action-planning - similar brain areas activated in modern piano playing. This suggests that language may not have played a crucial role in the evolution of early stone tool production.

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Adult subcortex processes numbers with the same skill as infants

A recent study published in PNAS found that adult humans' subcortex can process numbers at the same level as infants and other lower-order species. The researchers used a stereoscope to present visual stimuli to one eye or both eyes and observed that numerical judgments were better when the quantities differed greatly.