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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Evolution: Revelatory relationship

A new study supports the idea that hydrogen played a crucial role in the emergence of eukaryotes, the first nucleated cells. The research suggests that the Lokiarchaeota, an enigmatic group of microorganisms, use hydrogen for metabolism, providing evidence for the 'hydrogen hypothesis' of eukaryote evolution.

Genome of symbiotic cryptic cyanobacterium

The OmCyn cyanobacterium has been found to have a worldwide distribution, hidden by its symbiotic relationship with a dinoflagellate. The discovery represents an ecologically important group of cyanobacteria and suggests that other undiscovered cryptic cyanobacterial lineages may exist.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Parasitology: Exotic signaling mechanism in pathogens

Researchers discovered an unconventional signaling pathway in Trypanosoma brucei, a parasite that causes sleeping sickness. The study identifies a new compound activator for protein kinase A (PKA), potentially leading to targeted therapies.

Study of archaeal cells could teach us more about ourselves

Scientists studying archaeal microorganisms discovered essential genes critical for their growth, which may hold clues to the origin of eukaryotic cells. The research also found that archaea have unique surface structures that provide protection, contradicting previous beliefs.

Not in the DNA: Epigenetics discovered in single-celled archaea

University of Nebraska-Lincoln researchers found epigenetic traits in Sulfolobus solfataricus, a species of archaea that thrive in acidic environments. The discovery could accelerate the study of epigenetics in humans, potentially leading to new insights into trait inheritance and management.

Scientists discovered a set of enzymes to create glowing organisms

Scientists have identified the biochemical pathway that allows bioluminescent fungi to light up and created an artificially luminescent eukaryote by inserting the necessary genes into a non-glowing yeast. The discovery could lead to widespread applications, including glowing plants and animals.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Origin of photosynthesis in eukaryotes

A study suggests that photosynthetic eukaryotes originated around 1.9 billion years ago through endosymbiosis with cyanobacteria, giving rise to archaeplastids including land plants and algae. The analysis reveals that the common ancestor of these organisms likely emerged in freshwater habitats.

Origins of DNA folding suggested in archaea

A study published in Science reveals that archaeal DNA folding is identical to the process found in more complex organisms, suggesting an early prototype for the eukaryotic nucleosome. This discovery sheds light on the evolutionary origins of genome folding and raises questions about the common ancestor of life.

Diversity without limits

Researchers assembled a comprehensive tree of prokaryotic life, exploring grand patterns of evolutionary change. The findings suggest that diversity is not limited by existing diversity or environmental changes, but rather results from random lineage splitting.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Life as we know it most likely arose via 'long, slow dance'

Researchers propose that eukaryotic life arose through a gradual transfer of molecular machinery from archaea to bacteria. The discovery of Lokiarchaeum's genome reveals a complex organization, sparking debate about the earliest stages of eukaryogenesis.

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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Parasites reveal how evolution has molded an ancient nuclear structure

A research team has mapped the structure of a unique nuclear pore complex found in trypanosomes, an ancient parasite species diverged from yeast and humans. The study reveals that the architecture of the inner ring is similar across different eukaryotes, while the outer ring exhibits distinct features, suggesting an ancient origin.

Surprising source for ancient life biomarker found

Stanford scientists discover tetrahymanol, a fatty molecule used as an indicator for life on early Earth, in bacterial membranes. The finding suggests many bacteria might produce the lipid, challenging conventional wisdom.

Eukaryotes: A new timetable of evolution

The discovery of microfossils in rocks dating back 1.5 billion years has confirmed the existence of eukaryotes, shedding light on their evolution and origins. The analysis of steroid molecules revealed no signs of contamination, contradicting previous findings.

Surprise from the deep ocean

A new study has uncovered Lokiarchaeota, a missing link in the evolution of eukaryotes, revealing unexpected complexity in its genome. The discovery provides insights into the emergence of organelles and cellular structure in early eukaryotic cells.

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Fossil of multicellular life moves evolutionary needle back 60 million years

A team of researchers has found fossils indicating complex multicellularity in ancient organisms around 600 million years ago, contradicting previous interpretations. This discovery sheds new light on the evolution of multicellular life and could have significant implications for our understanding of the Cambrian Explosion.

Scientists date prehistoric bacterial invasion still present in today's cells

Researchers date cyanobacterial invasion into one-celled plants to 900 million years ago, revealing new insights into the origins of photosynthesis. By analyzing fossil and genetic evidence, they estimated the age of this ancient event, providing a more precise timeline for the evolution of plant and animal cells.

New data challenge old views about evolution of early life

A UC Riverside-led research team tested the hypothesis that low zinc levels delayed eukaryote diversification, finding instead high seawater zinc availability throughout Earth's history. The study suggests that ferruginous deep oceans and volcanic activity maintained stable zinc levels.

About one million species inhabit the ocean

A new study suggests that up to one million marine species may inhabit the world's oceans. The current number of identified species is around 230,000, but estimates vary widely, ranging from 540,000 to 972,000. Despite this uncertainty, researchers agree that only about 1/3 of ocean biodiversity has been discovered.

Kestrel 3000 Pocket Weather Meter

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In the beginning...was the beaker?

Researchers at Brookhaven Lab used cryo-electron microscopy to visualize how protein machines bind to DNA strands, setting up for duplication. This study may lead to new ways to attack cancers by targeting the basic process of cell division.

Study analyzes role of PARP enzyme in eukaryotes

Researchers analyzed evolutionary history of poly(ADP-ribose)polymerase (PARP) superfamily in eukaryotes, finding ancestral proteins with diverse functions. The study suggests that the PARP superfamily is larger than previously documented and will grow as more eukaryotic genomes become available.

Shining a light on trypanosome reproduction

Trypanosomes, a distant branch of the eukaryote tree, have been found to reproduce sexually through meiosis, a process previously thought unclear. The study uses fluorescently-tagged proteins to visualize the process inside the tsetse fly.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Life on Earth got bigger in 2-million-fold leaps, says Stanford researcher

A Stanford researcher has quantified the enormous size jumps of life on Earth, finding two major leaps: one 1.6 billion years ago and another 600 million years ago. These increases were triggered by significant boosts in atmospheric oxygen levels, which enabled eukaryotic cells to develop and multi-cellularity to emerge.

International team of scientists discover clue to delay of life on Earth

An international team of scientists has discovered a crucial clue to the delay of animal life on Earth, suggesting that oxygen and molybdenum deficiencies in ancient oceans may have hindered complex life's evolution. The research, published in Nature, sheds light on the development of early life and its connection to ocean chemistry.

Rigol DP832 Triple-Output Bench Power Supply

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Small, but mighty

Scientists have uncovered the complete genome sequence of Ostreococcus tauri, a tiny eukaryote that plays a significant role in ocean climate dynamics. The study reveals the organism's complex genetic makeup and its ability to perform photosynthesis, which has major implications for carbon cycling.

Study shows our ancestors survived 'Snowball Earth'

New research finds ancient oil droplets containing biomarkers from eukaryotes and cyanobacteria that lived before the planet's glaciation, contradicting previous theories. The study suggests oxygen was produced long before the atmosphere became oxygenated, supporting life in extreme conditions.

Using RNA as your guide

In archaea, a specialized enzyme uses RNA as a guide to pseudouridylate specific RNA molecules. This modification impacts the stability, localization, and translation efficiency of target RNAs.

Hidden sex life of an early eukaryote revealed

Researchers found evidence for meiosis in Giardia, a single-celled protist thought to be a modern representative of an early diverging eukaryotic lineage. The discovery suggests that the earliest eukaryotes diverged after the advent of meiosis, providing new insights into sexual evolution.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

UI researchers advance understanding of sexual evolution

Researchers found evidence of meiosis in Giardia intestinalis, a unicellular protist parasite, suggesting that eukaryotes have been capable of sex for a long time. The discovery provides insight into the evolution of sexual reproduction in eukaryotic cells.

UCLA molecular biologists uproot the tree of life

Researchers found that two prokaryotes merged to form the first eukaryote, creating a 'ring of life' that has significant implications for all multicellular forms of life. The study sheds light on the origins of eukaryotes and their genetic background.