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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Cousin of crop-killing bacteria mutating rapidly

A newly identified species of Liberibacter, a family of bacteria known for causing citrus greening disease, is rapidly evolving its ability to infect insect hosts. The research team found 21 genes associated with infectious qualities and identified mutations affecting pilus proteins that allow the bacteria to move into host insects.

Hundreds of large habitat shifts have shaped life on Earth today

An international team has uncovered that eukaryotes have made hundreds of big leaps from sea to soil and freshwater habitats during their evolution. This reveals that adapting to a different salinity is difficult, even for microbes, but still allows them to occupy vacant ecological niches.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Researchers unveil key processes in marine microbial evolution

A recent study has revealed that the great current diversity of eukaryotes is largely due to the large number of habitat transitions between sea and land over millions of years. Microbial eukaryotes have made hundreds of leaps from one habitat to another, allowing them to occupy vacant ecological niches.

Safe steps for using probiotics to revive biodiversity

A newly published framework outlines steps for administering probiotics to wildlife, prioritizing native species, effective dosages, and delivery systems. The goal is to restore beneficial bacteria and protect key symbiotic relationships, while considering potential risks and side effects.

Chemists create artificial protein that peers into Earth’s chemical past

Researchers at Ohio State University have developed an artificial protein that could provide new insights into chemical evolution on early Earth. The protein, inspired by a key enzyme in energy production, has been shown to build molecules one step at a time, shedding light on how organic chemistry matured on the planet.

Did our ancestors have better microbiomes? For maize, maybe!

Researchers found that domesticated maize recruits different microbes from soil than its wild ancestors, including those involved in nitrogen cycling. This shift may be driving the need for synthetic fertilizers, but understanding the ancestral microbiome could help breed crops more sustainably.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Geological activity can rapidly change deep microbial communities

Researchers at Stanford University found that deep subsurface microbial communities can change in a matter of days, driven by geological activity rather than environmental pressures. The study provides new insights into the complex dynamics of these underground ecosystems and opens up possibilities for mapping the deep subsurface.

DNA evolves at different rates, depending on chromosome structure

A recent study by Indiana University researchers found that the structure of DNA storage in archaea affects its evolution rate. The study discovered that compacted DNA compartments change at a faster rate than less compacted ones. This discovery has potential impacts on research on genetic diseases like cancer.

Chromatin originated in ancient microbes one to two billion years ago

Researchers at the Center for Genomic Regulation (CRG) found that chromatin, a genetic architecture that protects DNA and regulates gene expression, originated in ancient microbes between 1-2 billion years ago. This eukaryotic innovation has been essential for life since its emergence.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

How diverse microbial communities remain stable

A novel computational method estimates the level of connectivity in bacterial communities, revealing that species diversity is limited by interaction strength. Understanding these stability principles is essential for developing medical treatments and preserving the environment.

UNH research finds a genomic time machine in sea sponges

A novel approach to understanding sponge evolution reveals two distinct microbiome compositions that led to different feeding strategies and predator protection. The discovery provides insights into the Earth's past and could reveal aspects of ancient ocean chemistry.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Microbes and minerals may have set off Earth’s oxygenation

Scientists propose a new mechanism by which oxygen accumulated in the atmosphere, shifting the planet out of its low-oxygen equilibrium. Interactions between certain marine microbes and minerals in ocean sediments may have prevented oxygen consumption, setting off a self-amplifying process.

Three Exeter researchers win Discovery Fellowships

Three University of Exeter researchers Dr Jasmine Ono, Dr Luis Yanez Guerra and Dr Jane Usher have been awarded BBSRC Discovery Fellowships for innovative research in biotechnology and biological sciences. They will focus on improving scientific knowledge to develop better treatments for human fungal pathogens and understanding the ori...

Your microbiome shapes your life. But where did it come from?

A team of researchers discovered that chance plays a significant role in the formation of individual gut microbiomes, with genetic, diet, and environmental factors influencing the odds of colonization. The study's findings have major implications for treatments like fecal transplants and probiotics.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Moon develops targeted, reliable, long-lasting kill switch

A new, reliable kill switch has been developed to eliminate genetically modified microbes that pose environmental risks. By inserting multiple kill switches into the microbial DNA, a success rate of one in billion microbes was achieved during experiments.

Cover crops help squash squash their pathogens

A recent study found that cover cropping can reduce the population of Pseudomonas syringae, a common bacterial pathogen affecting agricultural crops. The researchers also discovered an increase in beneficial microbes such as Sphingomonas and Methylobacterium, which have been used as biocontrol agents against pathogens.

Extremely harsh volcanic lake shows how life might have existed on Mars

A recent study discovered that a hydrothermal crater lake in Costa Rica's Poás volcano is home to a diverse range of microorganisms, including the single 'extremophile' genus Acidiphilium. These bacteria have adapted to survive in extreme conditions, such as high temperatures and toxic metals, which may be similar to those found on Mars.

The genomic structure of microbial communities can predict metabolic activity

A new study reveals that the genes present in a microbial community can predict its dynamic metabolic activity, with implications for the nitrogen cycle and other biogeochemical processes. The research provides insights into how scientists can infer metabolite dynamics from aggregate gene content, design microbial communities for speci...

Tell me what you eat and I will tell you how your microbiota evolves

A new study found that diet can cause significant changes in the gut microbiota, leading to long-lasting genetic alterations. In mice, a low-fiber Western-style diet led to the emergence of adaptive mutations in a key species of bacteria, shaping its function and increasing host susceptibility to infection.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Halting antibiotic resistance is a little less futile

Rice University researchers developed a microfluidic platform to analyze how infectious bacteria evolve resistance to antibiotics. The platform allows for controlled environments and fine-tuning of conditions, revealing previously unknown pathways to resistance.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Microbe sneaks past tomato defense system, advances evolutionary battle

A new study reveals that Xanthomonas euvesicatoria has evolved to evade the immune system of tomato plants by changing a single amino acid in its flagellin proteins. This finding poses significant challenges for breeding disease-resistant tomato varieties, forcing farmers to rely on fungicides and copper treatments.

Science snapshots from Berkeley Lab

Researchers have created a new approach to edit genes within specific bacteria in a community using CRISPR-Cas9, enabling targeted genetic modifications. This technology could be used to track edited microbes and potentially treat diseases like digestive issues or create more resilient crops.

A step toward “living biotherapeutics”

The coating protects bacteria during the freeze-drying and manufacturing process, allowing them to be used therapeutically. The researchers tested the coating on a strain of E. coli and another species that aids in digestion of plant starches.

Study digs up roles bacteria play in global carbon cycle

Researchers at Cornell University developed a novel method to track microbes and understand their role in processing soil carbon. The study found that different types of bacteria have varying strategies for assimilating carbon, categorized into guilds based on their access to food.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Woodrat microbiomes: It’s who you are that matters most

A University of Utah team analyzed woodrat gut bacteria and found that evolutionary history plays the greatest role in shaping microbiome structure. Diet and geography also influenced microbiome composition, but host relatedness was the strongest predictor in both wild and captive populations.

Using microbes to make carbon-neutral fuel

Researchers at Washington University in St. Louis have developed a way to train microbes to produce a readily usable biofuel from CO2, solar panel-generated electricity and light. The resulting n-butanol is an authentically carbon-neutral fuel alternative that can be used in blends with diesel or gasoline.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

DNA tangles can help predict evolution of mutations

Researchers found that DNA tangles create mutational hotspots in bacterial genomes, influencing evolution. By altering the sequence to prevent hairpin tangles, they can predict how microbes might mutate under selective pressure.

Understanding variations in Salmonella virulence

Researchers from the University of Seville discovered that a single amino acid mutation in Salmonella enzymes enables them to modify more proteins in infected cells, leading to increased virulence. This finding has significant implications for developing inhibitors as alternative antibacterial treatments.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Defence system protects African salmonella from attack by viruses

Researchers have identified a new prophage-mediated defence system in Salmonella Typhimurium ST313 called BstA, which efficiently suppresses phage attacks. This discovery opens up a new avenue of research and could potentially lead to the development of new biotechnologies.

Microbiology: Bacterial evolution in ancient sub-seafloor sediments

A new study reveals that bacterial evolution can occur in ancient sub-seafloor sediments with low nutrient availability. The genomes of bacteria isolated from these sediments show a high proportion of pseudogenes and reduced genetic recombination, leading to the accumulation of deleterious mutations.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Data scientists go to the mat to learn about microbial networks

Researchers at Rice University are developing novel computational approaches to track environmental microbiome dynamics over time, across species and after perturbations. The team will use biofilm-based 'species abundance networks' on scaffolds to observe how they form their own genome-exchange networks.

A long day for microbes, and the rise of oxygen on Earth

Researchers found that the oxygen produced by photosynthesis is limited by the time available during shorter days, as late-rising cyanobacteria need a few hours to photosynthesize and produce oxygen. This discovery suggests that changes in day length may have impacted global oxygen levels over Earth's history.

Seven degrees from one trillion species of microbes

A global network of microbiomes reveals that only six 'relatives' (or seven 'steps') separate any two microbiomes on Earth, indicating a common origin. The study also sheds light on the interactions between microbes in different ecosystems and their responses to climate change.

Capturing the huge impacts of tiny organisms

Researchers are developing a new technique to study microbes in conditions that mimic their native environment, facilitating the growth of difficult microbial species. This technology has potential applications in medicine, biotechnology, and bioremediation, including the controlled delivery of healthy gut bacteria into the body.

GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

How the oral microbiome evolved

A recent study analyzed 124 dental biofilm metagenomes from various primate species, revealing 10 core bacterial genera that have been maintained throughout African hominid evolution. These microbial groups played a key role in oral biofilms for over 40 million years and adapted to starch-rich diets early in human evolution.

The surprising evolutionary history of our oral bacteria

A new study reveals that the oral microbiome of ancient humans and Neanderthals is surprisingly similar, with some bacterial strains shared between species. The analysis of fossilized dental plaque also suggests that early humans consumed starch-rich foods, potentially contributing to brain evolution.

Soil bacteria evolve with climate change

Researchers at UCI found that soil microbes can evolve in response to climate change, changing genetic diversity in 18 months. This rapid evolution has implications for how soil ecosystems respond to future climate conditions.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Away with the bad cliché: Bacterial complexity is often underestimated

A new German research project aims to challenge the perception of bacteria as simple organisms by studying their complex behavior and multicellularity. The study seeks to gain a deeper understanding of bacterial life forms, with potential applications in combating antibiotic resistance and developing innovative biocatalysis.

Scientists discover how microorganisms evolve cooperative behaviors

Researchers from Institute for Systems Biology uncover evidence that mutations generate positive genetic interactions among rare microbial individuals, increasing cooperativity and enabling their persistence. The study also reveals parallel evolution underlying the co-evolution of two organisms in a mutualistic community.

Cell-autonomous immunity shaped human evolution

Researchers argue that cell-autonomous immunity, a ancient defense mechanism in human cells, plays a crucial role in shaping human evolution. Understanding this concept is essential for developing effective treatments for diseases like sepsis, as traditional approaches often fail due to the immune system's conserved mechanisms.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

To understand the machinery of life, this scientist breaks it on purpose

Researchers used ancestral sequencing to study the translational machinery in bacteria, finding that evolution prioritizes fixing problems over completing them. The team discovered that natural selection favors mutations with the largest fitness advantage, leading to a myopic approach that neglects other cellular modules.