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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Animals resistant to drunken behavior offer clues to alcoholism's roots

Researchers have discovered that animals with altered cytoskeletal structures are less susceptible to alcohol's intoxicating effects. A team of Italian researchers found mice lacking a gene that influences the cellular skeleton became less sensitive to ethanol exposure, leading to increased drinking and reduced neurological damage.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Williams Syndrome, the brain and music

A study published in NeuroImage found structural abnormalities in the planum temporale of individuals with Williams syndrome, which may explain their enhanced auditory skills. Despite smaller brain volumes, the temporal lobe was found to be of normal volume, suggesting that other factors contribute to their unique abilities.

Genetic links to schizophrenia focus of international study

An international team, led by UCLA's Roel Ophoff, is conducting a four-year study on schizophrenia that will analyze the human genome of approximately 850 Dutch patients and 750 control subjects to pinpoint related genes. This approach aims to separate false clues from true genetic variants associated with the disorder.

Early to bed, early to rise

A team of German scientists has uncovered a genetic basis for the human familial advanced sleep phase syndrome (FASPS), which causes people to go to sleep and wake up early. The study identified a mutated gene, PER2, and its phosphorylation sites that lead to the disorder's symptoms.

Single genetic defect produces specific cognitive deficit in mice

Researchers found that mice with reduced levels of the acetylcholine transporter had impaired object recognition and social recognition abilities. The study suggests that cholinergic deficits may contribute to cognitive decline in disorders like Alzheimer's disease and aging.

UCLA study uncovers new risk factor for schizophrenia

A new risk factor for schizophrenia has been identified by UCLA scientists, with infants having a specific immune gene that closely resembles their mothers' being more likely to develop the disease. The study suggests that this genetic match may increase fetal susceptibility to schizophrenia, particularly in females.

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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

University of Washington researchers discover novel genomic disorders

Scientists identified several abnormal genetic events in children with mental retardation and pinpointed a specific deletion on chromosome 17, which may account for ~1% of cases. The discovery provides unprecedented insight into the underlying biology and mechanism of genomic disease using NimbleGen's high-resolution CGH microarrays.

Einstein researchers take the pulse of a gene in living cells

Researchers at Einstein College of Medicine have observed a phenomenon where a gene plays a major role in organism development, displaying pulses of transcription that turn on and off at irregular intervals. This discovery could enable precise regulation of development by allowing genes to be turned on and off as needed, similar to a t...

Recent, rapid climate change is driving evolution of animal species

Research by University of Oregon scientists reveals that rapid climate change is leading to heritable genetic changes in animal populations. This includes changes in timing of seasonal events, such as earlier reproduction and migration, rather than adaptations to temperature increases.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research

Researchers found that Nepali rhesus macaques are genetically similar to Indian-origin animals, which could provide a new alternative for HIV/AIDS research. The study suggests that these animals may be representative of Nepali rhesus macaques in general, and their use in research could help address conservation concerns.

Genetic variants and breast cancer risk, genetics and suicidal behavior, and more

Researchers investigated the association between genetic variants and breast cancer risk, as well as apolipoprotein E (apoE) plasma levels and cardiovascular mortality in older adults. The study found no link between CHEK2 gene variants and breast cancer risk, while high apoE levels were associated with increased cardiovascular mortali...

GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Ancient DNA provides clues to the evolution of social behavior

Researchers used ancient and modern DNA to study the decline of Ctenomys sociabilis, a colonial tuco-tuco species. The analysis suggests that population bottlenecks and environmental changes led to the loss of genetic diversity, but also hints at the evolution of social behavior.

Study reveals new genes for excessive alcohol drinking

Researchers have discovered nearly 4,000 genes associated with high and low alcohol consumption in mice, shedding light on the molecular mechanisms underlying excessive drinking. These findings could lead to new targets for treating alcoholism.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

$10 million gift funds innovative predictive health study

The Fairbanks Institute will conduct a long-term predictive health study using biologics and medical informatics to identify risk factors for cardiovascular disease. Researchers will monitor participants over years to understand biological compensation and gene-environment interactions.

Aggression-related gene weakens brain's impulse control circuits

Research suggests that a specific gene variant linked to aggression impairs the brain's ability to regulate impulses and emotions, particularly in males. This impairment can lead to increased reactivity in the fear hub and reduced activity in higher brain areas that regulate emotional responses.

Active inbreeding avoidance in wild capuchin monkeys

A 14-year study of wild capuchin monkeys reveals that fathers almost never mate with their daughters, despite alpha males siring most offspring from unrelated females. This suggests the evolution of sophisticated behavioral barriers to prevent inbreeding within individual populations.

Engineered mouse mimics cognitive aspects of schizophrenia

Researchers created a genetically altered mouse strain with overexpressed dopamine receptors in the striatum, which showed specific cognitive deficits similar to human schizophrenics. The study suggests that cognitive symptoms may arise from subtle genetic differences in the dopamine receptor gene.

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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Daughters of alcoholics

Daughters of alcoholics exhibit distinct risk factors, with behavioral undercontrol being a strong mediator for both genders. Gender-specific differences are observed in behavior and the impact of parental alcoholism history, particularly for women.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

New study examines how sense of smell affects mating and aggression in mice

A new study published in Nature Neuroscience found that male mice require intact functioning of the main olfactory epithelium (MOE) to detect pheromones that elicit sexual behavior and fighting. The MOE plays a crucial role in regulating mating and aggression in mice, highlighting the importance of this sensory system.

Dog genome sequence and analysis published in Nature

The study unlocked genetic variation among dog breeds, revealing ~2.5 million individual genetic differences among breeds that can be used to locate the genetic contributions to physical and behavioral traits. The analysis also found evolutionary conservation with humans, highlighting regions of the human genome that are highly preserv...

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

The food you eat could change your genes

Scientists have found that injecting a specific amino acid into rats can alter their gene expression, raising hopes for potential treatments for diseases. The study also showed that certain nutrients can influence gene expression in animals even after birth, sparking interest in the role of diet in shaping our genes.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Malaria risk – it's not all in the genes

Researchers found that household-related factors account for a similar level of variation in susceptibility to malaria as host genetic factors. Children living in high-risk households had twice as many infections per year as those in low-risk households.

New genetic link to high blood pressure found

Researchers discovered a significant link between a genetic variation in the DRD4 gene and high blood pressure, which could help explain individual risk factors. The study also sheds light on how this gene affects kidney function and blood pressure regulation.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Hitting the bottle with the genetic basis for alcoholism

A new study reveals that decreased CREB gene function in the brain's central amygdala is involved in anxiety and excessive alcohol drinking behavior. This genetic determinant creates a vulnerable neural substrate that interacts with alcohol to create abuse potential.

Brain protein linked to alcoholism and anxiety

A study published in the Journal of Clinical Investigation found a link between a brain protein called CREB and anxiety-related behaviors in rats. Lower levels of CREB were associated with high anxiety and increased alcohol consumption in genetically predisposed rats, suggesting that drinking may be used as a self-medication strategy.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

JCI table of contents October 3, 2005

A new study published in The Journal of Clinical Investigation found that decreased function of the CREB gene transcription factor is involved in anxiety and excessive alcohol drinking behavior. Decreased CREB function was shown to be important for maintaining high anxiety and excessive alcohol drinking. This genetic determinant create...

A novel method to measure circadian cycles

Scientists have developed a novel method to measure circadian cycles in human cells, finding large differences between individuals' rhythms. The study used skin samples infected with a fluorescent virus to track circadian gene expression, confirming the human circadian cycle length of 24.5 hours.

Environment, not genes, key in family relationships

Researchers analyzed data from 674 families with same-sex adolescent pairs to explore the connections between environmental factors and individual traits. The study found three key factors: overall adjustment, independence, and parental monitoring, which explained the complexity of family relationships.

Gambling monkeys give insight into neural machinery of risk

In a study published in Nature Neuroscience, researchers found that monkeys overwhelmingly preferred to gamble by looking at the 'risky' target, even when it yielded smaller rewards. The neurons in the posterior cingulate cortex of the brain were found to be signaling the monkeys' subjective valuation of the target.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Disparate mole-rats

Researchers studied the genetic markers of African mole-rats to understand their complex social behavior. They found that these microsatellites can reveal how traits pass from mother to offspring, potentially explaining why family members support a single mother naked mole-rat.

Recent developments on the genetics of alcohol use

Research on the genetics of alcohol use has identified polymorphisms in ADH and ALDH enzymes that may explain individual differences in alcohol metabolism, as well as chromosomal regions linked to suicidal behavior, conduct disorder symptoms, and alcohol dependence. Additionally, serotonin receptor variations have been found to play a ...

Flies on speed offer insight into the roles of dopamine in sleep and arousal

Researchers found that genetically engineered flies with turned-off dopamine cells or those receiving dopamine inhibitors display converse behavioral effects to normal flies on methamphetamine. The study suggests dopamine plays a crucial role in modulating neuronal activity and assigning saliency to sensory stimuli.

Is it me… or my genes?

Edwin Rydberg wins prestigious EMBO Science Writing Prize with his essay Through The Illusions, exploring the link between DNA changes, smoking and schizophrenia. His work showcases a fascinating combination of factors, inspiring new research in popular science writing.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Genes exert powerful effect on sexual behavior

Researchers found that genetic manipulation of the fruitless gene in females led to classic male sexual behavior patterns, including courtship dances. The study suggests a strong biological basis for sexual behavior and orientation in animal species.

Single gene is genetic switch for fly sexual behavior

A new study found that a single gene, Fruitless, is responsible for controlling fly sexual behavior. The researchers discovered that female flies with the male version of the protein behave like males and engage in nearly identical courtship rituals.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Examining the serotonin transporter gene and family function

A Swedish study found that adolescents with a specific genetic variation in the serotonin transporter gene and poor family relationships are more likely to engage in high-intoxication frequency. Conversely, a favorable family environment can protect against genetic vulnerability. The study suggests an interaction between genetic and en...

Remote control flies?: Fly behavior controlled by laser light

Researchers use genetically engineered flies to demonstrate controlled neural manipulation, offering a promising approach for studying behavior and potentially treating neurological disorders. The system involves triggering molecular lock-and-key interactions with laser light, enabling precise activation of specific nerve cells.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Autistic children's abnormal metabolic profile findings

Research reveals that autistic children have significantly lower levels of glutathione, a major intracellular antioxidant, indicating increased oxidative stress. Genetic polymorphisms in three genes (catecho-O-methyltransferase, transcobalamin II, and glutathione-S-transferase M1) are also found to be elevated in autistic children.

Genes for alcohol consumption identified

A large-scale study identified a genetic basis for certain behaviors, including alcohol consumption, suggesting that genetic make-up may influence drinking habits. The research focused on the dopamine D2 receptor gene (DRD2) and found a strong association between this gene variant and alcohol consumption.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.