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Hepatic hydrogen sulfide levels are reduced in mouse model of progeria

Researchers investigated hepatic hydrogen sulfide production in a mouse model of Hutchinson-Gilford Progeria Syndrome (HGPS) and found reduced H2S levels in RC-fed mice, with partial rescue on high-fat diet. This study suggests that accelerated aging in HGPS may be partially explained by reduced hepatic H2S levels.

SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJul 11, 2023