Researchers identified a mutation in the DMRT3 gene, crucial for ambling gaits, pacing and high-speed trotting in horses. In mice, this gene reveals fundamental knowledge about neural circuits controlling leg movements.
Dr. Ley's work on whole genome sequencing in AML has provided unprecedented insights into the disease, highlighting the importance of unbiased methods for discovering cancer-initiated mutations. His research also revealed that most AML mutations are benign background events, with only a handful contributing to pathogenesis.
Ecologists warn of potential unintended consequences of genetically engineered algae for biofuel production. Researchers argue for independent studies and adequate funding to explore potential risks, including survival in the wild, hybridization, and ecosystem disruption.
A recent analysis of avian feather lice reveals that their ancestors first colonized a particular group of birds and then radiated to different habitats, evolving into distinct species. The study found striking similarities in the adaptations of lice living in specific habitats on birds, which are attributed to convergent evolution.
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Recent advances in paleogenetics provide new insights into human evolution in Europe, showing that cultural and demographic events have shaped genetic variation among modern-day populations. The study reveals a more diverse range of mechanisms influencing genetic diversity than previously thought.
Researchers found that intervening on behalf of a victim can reduce bullying rates in humans' evolutionary past, leading to greater cooperation, empathy, and egalitarian moral values. This finding supports prior studies showing lower bullying rates in Scandinavian countries.
Researchers found that a slow response to reduced fitness accelerates Muller's ratchet, increasing the frequency of clicks. Even in unfavorable conditions, a small proportion of positive mutations can sustain populations, explaining the long-term maintenance of mitochondria.
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Researchers studied fruit fly chromosomes to understand the evolution of sex and gamete function. The study suggests that Meiotic Sex Chromosome Inactivation (MSCI) occurs in Drosophila, which has implications for human fertility and disease genetics.
The study found that Shigella sonnei, a bacterium previously thought to be more common in developing countries, is now spreading globally due to its high levels of drug resistance. The researchers suggest that vaccine development will be crucial in controlling the disease.
Researchers studying live oaks in eastern North America aim to understand how trees adapted to climate change during glacial periods. They believe that genetic changes, rather than extensive morphological alterations, allowed oaks to migrate and thrive in colder climates.
Scientists discovered virus-like genes in the DNA of a commonly studied fruit fly, which could enable research on whether animals hijack viral genes as an anti-viral defense. The study found that several types of fruit flies harbored genes similar to those that code for the sigma virus, a fly virus in the same family as rabies.
At the annual meeting of crystallographers, researchers presented groundbreaking studies on X-ray laser technology, deep-sea bacteria's pressure tolerance, and molecular mechanisms underlying bacterial resistance to antibiotics. The discoveries have significant implications for fields such as medicine, genomics, and material science.
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Elk and rhinoceros beetles use insulin to grow big horns and attract mates. A study by Michigan State University found that these traits are not handicaps, but rather honest indicators of quality. The research suggests that the males' insulin dependence provides a way for them to show off their strength and suitability as partners.
A recent genomic study of 15 African hunter-gatherers sheds light on human diversity, evolution, and ancient interbreeding. The analysis identifies millions of previously unknown genetic mutations and suggests that different groups evolved distinct traits to adapt to local environments.
A team of researchers has developed a novel method to search gene sequences and identify similar proteins across different kingdoms of life. They found that Actinobacteria, a group of single membrane bacteria, is the last universal common ancestor of all living species.
Researchers have identified genetic and blood serum markers that can predict the rapid progression of hepatitis C disease, allowing for more effective treatment decisions. Patients with high levels of a specific protein called MCP-1 are at risk for severe liver diseases.
Researchers at Leibniz-Institute DSMZ discovered that Roseobacter clade bacteria can exchange genetic characteristics through plasmids, allowing them to conquer new ecological niches. This horizontal gene transfer enables photosynthesis and enhances survival in diverse ocean habitats.
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Amanita mushroom evolution shifts from decomposing to symbiotic tree relationships, resulting in lost genetic capacity, according to Harvard researchers. The study reveals the transition came at a steep price, with genes associated with breaking down cellulose being sacrificed.
Researchers inserted ancient gene into modern-day E. coli and observed its evolution over 1,000 generations. The results showed that the ancient gene did not mutate to become more similar to its modern form, but rather the bacteria adapted through novel mutations.
A study published in the Genetics Society of America's journal found that genes responsible for immune response at youth are almost completely different from those in middle age. This discovery opens doors to understanding genetic interactions underlying why older people struggle more with infections.
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Scientists have discovered a new plant species in Scotland that has overcome infertility and formed a new hybrid. This rare example reveals the process of polyploidization, allowing the plant to restore fertility and thrive in the wild.
Scientists discovered that a widespread plant pest arose from the fusion of two unknown parent species just a few hundred years ago. The study reveals new insights into fungal evolution, showing that hybridization can lead to rapid speciation in plants and fungi.
The CIPRES Science Gateway is helping researchers unravel the enigmas of phylogenetics by making it possible to compare similarities and differences in DNA among large numbers of species. Phylogenetic studies are essential for understanding the history of life on earth, population changes, and evolutionary theories.
A study published in Aging Cell found that naked mole rats have high levels of the neuroprotective protein NRG-1, which is linked to their unusually long lifespan. The research suggests that this protein may be a key factor in maintaining brain health and preventing age-related decline.
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Researchers have recovered part of the genome of two individuals living in the Mesolithic Period, 7000 years ago. The study indicates that current Iberian populations don't come from these groups genetically. The genome found is the oldest from Prehistory and exceeds Ötzi, the Iceman, in 1700 years.
A new model suggests that frequency-dependent selection fosters genetic diversity by allowing different mutations to coexist and interact. This leads to higher diversity within populations, despite the potential decline in average fitness.
A classic study on male and female promiscuity has been called into question after UCLA biologists repeated the experiment using the same methods as the original. The team found that Bateman's conclusions about the relationship between mate number and offspring fitness were likely flawed due to a bias in his methodology.
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Researchers found uncoordinated gene expression in sponges, suggesting a mechanism for the evolution of neural synapses may be more ancient than thought. The study sheds light on the origins of the nervous system and its development in different animal species.
Research team studied genetic diversity of coelacanths in Africa, revealing low genetic diversity but specific patterns in certain regions. The study shows that coelacanths can continue to develop and adapt to new conditions despite their slow evolutionary rate.
A new study published in Genetics reveals a gene in Caenorhabditis elegans, similar to a human gene correlated with Alzheimer's disease, is involved in multiple metabolic pathways, including insulin. The discovery suggests that this gene plays a role not only in Alzheimer's but also in diabetes.
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Researchers at the University of East Anglia have discovered genetic differences between two Cryptosporidium parasite species. This breakthrough enables the development of a new gold standard test to quickly distinguish between the two species, allowing for earlier detection of outbreaks and tracing of their source.
Researchers at UCSB have successfully synthesized a semiconductor material through genetic engineering and molecular evolution. By directing the evolution of enzymes, they created new mineral architectures with unique properties, opening up possibilities for specialized materials.
A new Northwestern University study suggests that children of older fathers inherit longer telomeres, which may promote slower aging and facilitate extension of lifespan. The association is cumulative across multiple generations, offering insights into the evolution of aging.
A new method called comparative epigenomics uses interspecies comparison to determine the purpose of genes. By analyzing epigenomic marks in pluripotent stem cells, researchers were able to identify conserved epigenetic markers that can annotate the genome and clarify its regulatory function.
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Researchers found that direct reciprocity alone is insufficient for high levels of cooperation, emphasizing the need for population structure. Repetition can also boost cooperation when individuals interact with similar types, but excessive repetition can harm it.
Researchers found strong relationships between aggressive behavior and individual variation in genes related to testosterone processing in the brain. The study suggests that selection can shape aggression through changes in gene expression, independent of circulating testosterone levels.
Researchers found that parasitic flowers share large parts of their genome with host vines through horizontal gene transfer, and some borrowed genes are likely functional. The process may convey an evolutionary advantage to the flowers, which have replaced vertically inherited copies.
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Researchers will create an open, dynamic evolutionary framework to continuously update the tree of life, incorporating new biodiversity data. Computational tools will enable scientists to visualize and analyze the entire tree, facilitating comparative biology research and discovery of new medicines.
Researchers found that plant species reproducing sexually have stronger disease resistance due to increased adaptive evolution of the chitinase gene. This supports the theory that sex provides a genetic advantage in adapting to environmental changes.
A handful of genetic changes in early mammalian development created the complex structures of the human brain, including fine motor skills and cognitive abilities. Researchers identified key regulatory DNA regions that control the formation of the corticospinal system.
A team of researchers has developed a new genetic method called spatial ancestry analysis (SPA) that can model genetic variation in two- or three-dimensional space. SPA allows for the modeling of the spatial distribution of each genetic variant, enabling individuals to be localized on a world map based on their genetic information alone.
A new study by Durham University found that modern dog breeds have little in common with their ancient ancestors due to thousands of years of cross-breeding. The research analyzed genetic data from 1,375 dogs and showed that even breeds labeled as 'ancient' are not closer to the first domestic dogs.
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Researchers from the Heliconius Genome Consortium sequenced the Postman butterfly's genome and found promiscuous sharing of large DNA regions among closely-related species. This study reveals how hybrids can introduce new genes that help populations adapt, changing our understanding of adaptation in evolution.
Researchers discovered that colorful butterflies share traits to enhance their survival, including a rich repertoire of genes for olfaction and chemosensation. This cross-breeding allows them to acquire superior wing colors more quickly than evolving from scratch.
A recent study by Yale University researchers identified a pattern of gene activity in the human brain associated with autism and learning disabilities. The findings suggest that the same evolutionary mechanisms that enabled human cognitive abilities may also contribute to psychiatric disorders like autism.
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Researchers found that birds with multiple plumage colour forms evolve into new species faster than those with only one colour form. The study, published in Nature, used decades of data and genetic information to confirm a 60-year-old evolution theory.
Researchers have found that sex-linked chromosomes, particularly the W chromosome in female chickens, play a vital role in predicting fertility. The study's results support the idea that these chromosomes are unlikely to become extinct due to their importance in survival.
Researchers at McGill University turned back the clock to understand the evolution of sex differences in water striders. They found that male traits, such as elaborate antennae, were shaped by a struggle between sexes during mating, leading to increased mating success.
Researchers found a critical gene responsible for human brain features, duplicated around two million years ago. The partial copy's interaction with the original gene likely enabled cognitive changes and neuron development benefits.
A recent study published in PLOS Biology reveals that touch sensitivity is hereditary and linked to genetic mechanisms that support hearing. The research found a strong correlation between touch and hearing acuity in healthy human populations, suggesting that a single mutation may impair both senses.
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A new study identifies genes responsible for the Pygmies' relatively small size, suggesting hormonal pathways and immune system regulation as possible drivers. The research provides evidence of natural selection's role in shaping human traits, highlighting the importance of studying global diversity and evolutionary contexts.
A new treatment for argininosuccinic aciduria (ASA) has been discovered through nitric oxide supplementation. The study found long-term heart and neuropsychological improvements in mice and humans afflicted with ASA, a genetic metabolic disorder that causes ammonia accumulation and liver and nervous system damage.
Researchers have discovered that six unnatural nucleic acid polymers can share information with DNA, shedding light on the origins of life. The discovery opens up practical applications for molecular medicine, including new diagnostics and therapeutics.
A study in PLOS Computational Biology reconstructs the complete early evolutionary history of biological carbon-fixation. The researchers identified an early form of carbon fixation that achieved built-in robustness, allowing early life to compensate for internal chemistry issues.
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Scientists sequenced the Tasmanian tiger genome, revealing extremely low genetic variability due to geographical isolation. This limited genetic makeup makes the species highly susceptible to diseases and extinction.
Researchers from the University of Leicester discovered a new mechanism for cooperation in simple organisms, where individuals prefer those who resemble themselves. This 'similarity discrimination' effect can evolve quickly and powerfully in many social encounters, solving the long-standing puzzle of natural selection.
A new study using surname data reveals China's population structure has been shaped by both genetic drift and large-scale migration. The research found the highest levels of surname diversity at the Yangtze River basin, which is believed to be due to multiple historical migrations.
A study by Uppsala University researchers found that humans have a unique genetic variant allowing for efficient production of Omega-3 and Omega-6 fatty acids from vegetable oils. This adaptation is linked to the development of modern human brain capacity but increases the risk of cardiovascular disease in today's life situation.
The study reveals that changes to both genes and DNA stretches controlling gene activity have driven sticklebacks' adaptation to fresh water. Reused genetic regions, including armor genes and those involved in metabolism and developmental signaling, helped remodel fish into forms better suited to freshwater environments.
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A national team of scientists has created the first atlas of the human brain surface based on genetic information, revealing distinct genetic divisions that differ from traditional brain maps. This atlas provides a new tool for understanding how genes influence brain development and function.