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Brown biologist wins NSF's Waterman Award

Casey Dunn, a Brown University biologist, has been awarded the National Science Foundation's Alan T. Waterman Award for his groundbreaking research on the origins of diversity in life. The award recognizes his use of genomic and computational techniques to study complex multicellular organisms, including humans.

Missing DNA helps make us human

Researchers identified 510 missing genetic segments that distinguish humans from chimpanzees and other animals. These segments affect gene regulation, enabling traits like large brains and sensory whiskers. The study reveals how human evolution occurred through subtle DNA changes.

Evolution drives many plants and animals to be bigger, faster

A new study found that larger body size and earlier seasonal timing confer significant survival advantages in most plants and animals. This 'bigger is better' model of evolution is more common than the rare 'Goldilocks' model, where individuals with moderate traits tend to outperform those that are too small or too large.

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New research suggests that obesity and diabetes are a downside of human evolution

A new genetic discovery suggests that the loss of function in a human-specific gene called CMAH may contribute to the development of Type 2 diabetes. The study found that mice with this gene mutation developed insulin resistance and pancreatic beta cell failure, leading to decreased insulin production and impaired blood glucose control.

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Pollution triggers genetic resistance mechanism in a coastal fish

A study by Woods Hole Oceanographic Institution reveals that Atlantic tomcod have developed a genetic resistance to PCBs, allowing them to thrive in the polluted Hudson River. The researchers identified a single genetic receptor responsible for this adaptation, which may also impact their ability to break down other harmful chemicals.

Eggs' quality control mechanism explained

Scientists have made progress in understanding the role of p63 in eliminating damaged egg cells before they mature. A study found that a specific form of p63, TAp63a, is activated by DNA damage and triggers cell death.

A genetic mutation allows Hudson River fish to adapt to PCBs

A study found that a population of Hudson River fish evolved rapidly in response to PCB pollution, with a single gene responsible for their ability to withstand the toxic chemicals. The study's findings suggest that this genetic adaptation allowed the fish to survive lethal heart defects triggered by PCBs.

Global warming may reroute evolution

Research at the University of Michigan suggests that rising carbon dioxide levels associated with global warming may affect interactions between plants and insects, altering the course of plant evolution. The study found that plant families responded differently to elevated carbon dioxide in their production of chemical and physical de...

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Gonorrhea acquires a piece of human DNA

Researchers at Northwestern University have discovered the first evidence of a human DNA fragment in a bacterial genome, specifically Neisseria gonorrhoeae. This finding offers insight into the bacterium's ability to adapt to its human host and could lead to new strains of the disease.

Plants can adapt genetically to survive harsh environments

A Purdue University scientist discovered genetic evidence of how some plants adapt to live in unfavorable conditions. He found that the Arabidopsis thaliana plants with high sodium levels had a weak form of the gene HTK1, which regulates sodium intake distribution to leaves.

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Evolution by mistake

Researchers Joanna Masel and Etienne Rajon found that tiny populations evolve global solutions to prevent errors, while large populations rely on local solutions to tolerate mistakes. This discovery reveals the importance of 'cryptic variation' in natural selection, allowing organisms to adapt to new challenges.

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Men with macho faces attractive to fertile women, researchers find

Researchers found that men with masculine facial features are more attractive to women during their fertile phase, but this doesn't necessarily translate to increased attraction as life partners. The study, published in Evolution and Human Behavior, suggests that a man's intelligence has no effect on the extent to which fertile female ...

Hard-to-find fish reveals shared developmental toolbox of evolution

A recent study published in PNAS has confirmed that elephant fish, a shark cousin, share a common genetic process with mammals to form skeletal gill covers. The precise timing of gene expression during embryonic development produces dramatic anatomical differences between the two species.

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Heat shock protein drives yeast evolution

Researchers discovered that heat shock protein 90 affects a large portion of the yeast genome, revealing multiple traits simultaneously and instantly. This allows for rapid evolution of interdependent traits, leading to a better adaptation to stressful environments.

Genome of extinct Siberian cave-dweller linked to modern-day humans

A recent study has discovered evidence of a distinct group of 'archaic' humans existing outside Africa over 30,000 years ago. The Denisovans, as they are known, interbred with the ancestors of some modern humans and contributed 4-6% of their genetic material to present-day New Guineans.

Brain gene a trigger for determining gender

A study published in the Journal of Clinical Investigation has found that a brain gene called SOX3 can be activated to trigger male development in mice without a Y chromosome. This discovery has implications for understanding disorders of sexual development and may lead to new treatments.

The genetic basis of brain diseases

A team of scientists identified a set of brain proteins that accounts for over 130 brain diseases, including Alzheimer's and Parkinson's. The study provides a new way to study the evolution of the brain and behavior, and opens paths toward tackling these diseases.

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Age doesn't matter: New genes are as essential as ancient ones

A recent study found that nearly 30% of new genes in fruit flies were lethal when silenced, suggesting that new genes are equally important to older genes. The discovery challenges long-held beliefs about the importance of ancient genes and may have implications for human health.

What 'pine' cones reveal about the evolution of flowers

Genetic analysis suggests a single common ancestor triggered the emergence of flowers from pine cone-like structures, with water lilies as potential 'genetic fossils'. This discovery challenges expectations of distinct genetic instructions for each floral organ in early angiosperms.

Humans helped vultures colonize the Canary Islands

Genetic comparison reveals Egyptian vulture population in Canary Islands was established around 2500 years ago, matching human colonization date. Human activity led to divergent evolution and demographic expansion of vultures, assisted in their adaptation to new environment.

News tips from the Quarterly Review of Biology

Researchers challenge traditional views of individuality, proposing an evolutionary perspective that considers the fitness interests of component parts. Meanwhile, a surge in play research reveals its diverse causal mechanisms and evolutionary histories across animal species.

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Do our bodies' bacteria play matchmaker?

A new study from Tel Aviv University found that symbiotic bacteria inside a fruit fly greatly influence its choice of mates. The researchers isolated the bacterial species responsible for reproductive isolation in flies with diet-related mating preferences.

New research from Psychological Science

Researchers discovered that when a person's personality matches the prevalent personalities of others in a culture, it enhances positive effects on self-esteem and well-being. Additionally, social threats induce bodily freeze-like behavior in humans, while cultural differences in spatial representations affect time perception.

New statistical model moves human evolution back 3 million years

A new statistical model reevaluates the timeline of human evolution, suggesting divergence from chimpanzees occurred around 8 million years ago. The revised estimate improves upon previous findings by accounting for gaps in the fossil record and incorporating DNA evidence.

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No easy solution to genetic 'battle of the sexes'

A new study shows that even when a trait becomes sex-specific, knock-on effects can still disadvantage the other sex. Researchers found that in broad-horned flour beetles, larger mandibles in males were linked to increased mating success but also reduced female reproductive ability.

Main squeeze not needed for boa mom

Researchers at North Carolina State University have discovered that female boa constrictors can reproduce asexually, producing all-female babies with rare genetic traits. The study found that these WW-chromosome females retained their mother's color mutation and lacked any male influence.

Apple iPad Pro 11-inch (M4)

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ESHRE publishes new PGD guidelines

The European Society of Human Reproduction and Embryology has published new guidelines for Preimplantation Genetic Diagnosis (PGD). The guidelines cover the organization of PGD centers, laboratory methods, clinical protocols, and follow-up recommendations. PGS is also included in the guidelines.

Neurogenetics research sheds light on the causes of neurological disease

Recent advances in neurogenetics research have shed light on the genetic basis of human brain disorders, including Parkinson's and Alzheimer's diseases. Genetic discoveries have transformed clinical practice and provided new hope for patients and families affected by these devastating disorders.

100-million-year-old mistake provides snapshot of evolution

Researchers at the University of Leeds discovered a 100-million-year-old gene mutation that led to differences in how plants produce male and female parts. The study found that the mutation, which occurred around 20 million years ago, creates a new role for one of the duplicate genes, enabling it to make both male and female parts.

Apple MacBook Pro 14-inch (M4 Pro)

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City living helped humans evolve immunity to TB

A genetic variant reducing disease susceptibility is more prevalent in urban populations, suggesting exposure to TB led to its evolution. The study analyzed DNA samples from 17 populations across Europe, Asia, and Africa, revealing a link between city history and genetic resistance.

Research sheds light on altruism

Researchers at Michigan State University used digital evolution techniques to study altruism in species, finding that genes are more likely to help those physically similar to them. This challenges traditional kin selection theory and raises the possibility of life on other planets based on shared genes rather than familial units.

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Common orchid gives scientists hope in face of climate change

Scientists found that epigenetic variation can significantly influence the adaptive potential of individual species in marsh orchids, affecting evolutionary potential at a quicker rate. This discovery brings new hope to plant conservation and highlights the importance of environmental factors in altering inherited traits.

What causes hybrid vigor?

Researchers found that genetic variation, known as gene expression noise, can lead to increased vigour in species hybrids. This study provides a new explanation for hybrid vigor, covering both natural and domesticated varieties.

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Genetic mismatch keeps yeast species distinct

Researchers identify genes causing sterility in yeast hybrids, shedding light on reproductive isolation mechanisms. A genetic mismatch between nucleus and mitochondria is found to be a common cause of sterility in yeasts.

Frog killer caught in the act

A study published in the Proceedings of the National Academy of Sciences reveals that a fungal disease has decimated amphibian abundance and species diversity in Central America's highlands. The researchers used DNA barcoding to estimate the impact of the epidemic, discovering five new species were also lost.

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