Articles tagged with Gene Flow
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study found that wood warblers have borrowed color-related genes from neighboring species, leading to the evolution of diverse plumage colors. This gene exchange, known as introgression, occurred across multiple genera and is believed to have played a role in the group's rapid diversification.
Researchers at Stockholm University have uncovered the evolutionary history of the Norwegian lemming, revealing it to be one of the most recently evolved mammal species. The study found that the Norwegian and Siberian lemmings diverged approximately 35,000 years ago, with no evidence of interbreeding between them.
Researchers found that a narrow island separating the two species suggests recent speciation or extensive gene flow. The study proposes sexual selection as a key driver of species differentiation.
A new plant tissue has been discovered in plants essential for seed formation, which can increase crop yields. The 'Kasahara Gateway' structure functions as a gateway and is regulated by a gene called AtBG_ppap.
Researchers at UTA uncovered how the flowerpot snake repairs its DNA and prevents harmful mutations, shedding light on genetic repair mechanisms that could deepen our understanding of human gene evolution. The study also reveals surprising findings about reproductive strategies and immune-related genes in reptiles.
A new study deciphers ancient DNA from the Green Sahara, providing critical insights into the African Humid Period and its impact on human migration. The research reveals a unique genetic lineage that remained isolated for thousands of years, highlighting North Africa's heritage.
Researchers at Weill Cornell Medicine have discovered a precise mechanism by which an ion channel regulates its function, providing insights into fundamental biology and potential new treatments for diseases. The study identified a 'ball-and-chain' structure that plugs the channel, opening the way to modulate ion channel activity.
Researchers at Virginia Tech have developed a method to convert gut bacteria into mini protein factories that produce and release sustained flows of targeted proteins within the lower intestine. This approach eliminates a major roadblock in delivering drugs to this part of the body, offering potential treatment for chronic diseases.
Researchers at Virginia Tech have developed a way to convert gut bacteria into miniature protein factories that produce and release targeted proteins inside the lower intestine. This breakthrough could potentially treat chronic diseases.
A study on painted lady butterfly migrations found that environmental conditions, rather than genetic coding, drive their migratory patterns. The research revealed that butterflies can travel vast distances, crossing the Sahara Desert, without showing significant genomic differences between short and long-distance migrants.
A groundbreaking study finds evidence of female political and social empowerment in ancient Britain, where land was inherited through the female line. This system, known as matrilocality, was found to be widespread across Iron Age Britain, with dominant matrilines established before 400 BC.
Researchers have created a new circuit model that accounts for small changes to the sensor's behavior, allowing it to detect protein or DNA molecules from a sample. The device could lead to earlier diagnosis of diseases and more precise therapies tailored to each patient.
A new analysis of DNA from ancient modern humans in Europe and Asia has determined that Neanderthals interbred with modern humans from approximately 50,500 to 43,500 years ago. This period of interbreeding left Eurasians with many genes inherited from their Neanderthal ancestors.
Researchers have unraveled the precise timing and functional legacy of Neandertal gene flow into early modern humans. The study suggests that most non-African individuals harbor one to two percent Neandertal ancestry, with the majority tracing back to a single shared period between 50,000 and 57,000 years ago.
Geneticists deciphered aurochs prehistory by analysing 38 ancient genomes from Siberia to Britain. The study highlights diverse wild forms and the impact of climate change and domestication on their evolution.
A study of a 2000-year-old Yayoi individual's genome found that the majority of Japanese immigration came from the Korean Peninsula during the Yayoi and Kofun periods. The discovery provides new insights into the details of ancient immigration patterns to Japan.
Researchers at Texas A&M University have developed a method to recharge cellular mitochondria using nanotechnology, potentially extending healthy lifespans and improving outcomes for patients with age-related diseases. The molybdenum disulfide nanoparticles stimulate mitochondrial regeneration, helping cells generate more energy.
A fossilized Neanderthal, nicknamed 'Thorin', lived in a small isolated community for over 50,000 years before the species' extinction. The discovery reveals two distinct Neanderthal populations coexisted without exchanging genes, challenging previous assumptions about their population structure.
A recent genomics study of prairie chickens in five states has found evidence of hybridization between the two species, with no clear indication of genetic problems. The study suggests that these species may belong to the same species and challenges wildlife management nationwide.
Researchers developed MUSCLE, a method that combines single-molecule fluorescence microscopy with next-generation sequencing to profile complex biological processes. The technique enables simultaneous observation of vast arrays of samples, uncovering general trends and dynamic signatures.
A study by Prof. WEI Fuwen's team reveals that improved habitat connectivity has helped increase pandas' population density and reduced inbreeding via enhanced gene flow. This finding will guide future conservation management for endangered species.
A study by the Open Wild Wheat Consortium explains how Aegilops tauschii, a wild grass, contributed to the genetic diversity of bread wheat, enabling its rapid spread across different climates. This hybridization event allowed humans to settle down and form societies.
A recent study maps landscape connections to optimize elephant movement corridors and reduce genetic isolation, addressing a major conservation priority in southern Africa. The research provides insights into how elephants navigate their vast home ranges and identifies key routes to maintain gene flow across protected areas.
A new study reveals that the protein CRTC plays a crucial role in maintaining a healthy heart by ensuring it is neither too thick nor too thin. The research also shows that overexpression of CRTC causes cardiac hypertrophy, leading to adverse cardiovascular events.
A genome study has identified regional adaptations in American chestnut trees, informing restoration efforts and climate resilience. The research provides guidance for conserving genetic diversity across the Appalachian region, with a focus on preserving the most genetically diverse southern population.
Researchers assembled and analyzed the genomes of two distinct mulberry cultivars to pinpoint key genetic variations and the pivotal role of MaVHAG3 in anthocyanin accumulation. The study highlights intricate genetic and molecular processes regulating fruit coloration in mulberries.
Researchers found evidence of multiple waves of genetic intermingling between modern humans and Neanderthals, challenging previous theories. The study reveals a more intimate connection between early human groups than previously believed.
Researchers have discovered that the immune system evolves faster than other genes in the genome, particularly in mammals and birds. The study, published in Nature, used a unique model of genetically different mice to measure variation in immune cell types and identified key genes controlling their abundance.
A team of researchers has developed a novel genetic clock to determine the age of a large marine plant clone for the first time. The oldest identified seagrass clone is 1402 years old and was found in the Baltic Sea, making it older than other long-lived species.
Research finds that Huntington’s disease damages microscopic blood vessels in the brain, affecting coordination between neuronal activity and oxygenation. The study uses non-invasive measurement techniques to monitor disease progression and evaluate potential treatments.
A genetic study found that early summer fishing in the Baltic Sea targets larger salmon, leading to smaller fish and reduced population diversity. The study suggests that intensive fishing in the early season can cause evolutionary changes, affecting the age and size of Atlantic salmon before maturity.
Researchers found metal-tolerant trout populations in British and Irish rivers are genetically distinct due to high levels of metal pollution. The lack of genetic diversity in these populations makes them more susceptible to environmental changes.
Researchers found that miR-377 reduces MYC mRNA levels, leading to increased Bax and PTEN expression and decreased CDK4. This results in induced apoptosis, inhibited proliferation, and arrested cell cycle in prostate cancer cells.
A new pupfish family member has been discovered in New Mexico through genetic analysis. The study found that genetic drift was the primary driver of speciation, rather than natural selection. The researchers sequenced the entire genome of individual pupfish and compared them to previous genetic sampling.
A new study reveals that wildebeest populations which no longer migrate are less genetically healthy and more prone to decline. The loss of migration routes due to fencing and roads leads to lower genetic diversity, increased inbreeding, and reduced fertility.
Researchers investigated the phylogeographic history of Pterocarya hupehensis using cpDNA sequence variation analysis, RAD-seq reads, and ecological niche modeling. The study found two main haplotype lineages with genetic introgression in five populations, suggesting unidirectional gene flow.
Recent research connects biological domestication to early food globalization, proposing a new conceptual framework that challenges traditional narratives. Archaeological investigations have shown that plant and animal domestication entailed a more gradual transition spanning thousands of years across extensive geographies.
Researchers discovered that MEIS2 plays a critical role in activating genes necessary for the formation of inhibitory projection neurons, vital for motion control and decision-making. A MEIS2 mutation found in patients with intellectual disability disrupts these processes.
A study by Florida Atlantic University researchers found that severe hurricanes can increase the recovery of coral reef sponges by boosting the influx of juveniles and promoting gene flow. Genetic analyses revealed that populations of clonal marine species may benefit from increased frequency and magnitude of hurricanes to maintain gen...
Researchers found that genetic variants in the Fore population made them resistant to kuru, while a large influx of females migrated into the region due to flexible kinship systems. The study suggests an alternative theory on how Fore communities interacted with neighboring communities despite fears of kuru.
Researchers have discovered two genetic variants associated with generalized pustular psoriasis (GPP), a rare and serious condition characterized by widespread skin lesions and inflammation. These variants, found in the MEFV gene, may hold promise for new diagnostic and therapeutic approaches to GPP.
A recent study by Pusan National University scientists discovered the crucial role of PKM gene and EPHA2 pathway in HNSCC development. The research highlights the importance of HPV infection status in shaping the tumor microenvironment, enabling precision medicine for targeted treatment.
A study found that weedy rice's promiscuity allows it to crossbreed with wild rice, enabling it to adapt and outcompete cultivated rice. This process, called adaptive introgression, has contributed to the evolution of Southeast Asian weedy rice.
Researchers found that dysregulation of RNA transfer between cells in different tissues shortens lifespan in roundworms. They demonstrated that this phenomenon, termed Intercellular/Extracellular Systemic RNA imbalance (InExS), can be caused by an increase in RNA uptake from the environment, leading to a reduction in organism's lifespan.
Scientists used new techniques to analyze gene activities during mouse prenatal development, revealing hundreds of cell types and their formation. The study showed that massive transcriptional changes occur at birth, potentially necessary for survival outside the womb.
Researchers found that low-dose X-ray irradiation reduced lesion size and reversed motor deficits in TBI and ischemic stroke mice, demonstrating its potential as a therapeutic strategy. The treatment also accelerated substantial motor function recovery and promoted brain rewiring after stroke.
The Bay Area's Savannah sparrow subspecies is losing its unique adaptation to saltwater environments due to increased interbreeding with inland sparrows. Genetic analysis reveals a decline in the bird's genetic diversity, potentially affecting its ability to survive in tidal marshes.
A large-scale ancient human gene bank analysis revealed that genetic variants increasing MS risk were introduced by sheep and cattle herders 5,000 years ago. This finding explains the North-South Gradient of MS prevalence in Europe.
The study of 146 ancient Balkans reveals a diverse, cosmopolitan Roman Empire with African and Eastern European immigrants. The team identified three individuals of African origin and a large demographic influx from the Anatolian Peninsula during Roman rule.
Researchers found evidence of domesticated yak dating back 2,500 years in the southern Tibetan Plateau, revealing insights into animal domestication pathways and human adaptation to high-altitude environments. The discovery was made using a combination of ancient DNA sequencing and zooarchaeological analysis.
A recent study found that successive waves of migrations from Western Anatolia, central and northern Europe, and the Pontic-Kazakh Steppe shaped the Balkan population during the Roman Empire's reign. The influx of Slavic-speaking populations resulted in present-day residents having 30%–60% Slavic ancestry.
A single infusion of CRISPR-based gene-editing therapy significantly reduced LDL cholesterol levels in people with heterozygous familial hypercholesterolemia, a condition that increases heart attack risk. The treatment has shown potential as a long-term or permanent option for high LDL-C control.
A new study analyzing lice genetic diversity found that head lice arrived in the Americas twice – once with early human migrants and again during European colonization. This discovery supports existing theories on human migration and provides insights into how lice have evolved alongside humans.
Scientists have unlocked the genetic basis underlying the remarkable variation in body size observed in song sparrows, one of North America's most familiar and beloved songbirds. The study found eight genetic variants associated with body mass, largely responsible for the nearly threefold difference in body size across the species' range.
Researchers employed heat-induced FT overexpression to accelerate assessment of floral phenotypes after CRISPR knockout of LEAFY and AGAMOUS genes in poplar trees. The study successfully induced early flowering and demonstrated a wide range of inflorescence and floral forms.
Researchers analyzed DNA from 200-year-old fruit flies collected in Europe, revealing their surprising genetic similarity to modern flies. The study identified key genes that helped the flies adapt to changing environments, including a gene resistant to DDT pesticide.
Research reveals that female fruit flies pre-select for males with superior genes before influencing sperm storage to ensure compatible fertilization. The study provides new insights into the mechanisms and consequences of mate choice, shedding light on genetic variation and species evolution.
Researchers discovered that a mutation in the gene ACTA2 causes moyamoya disease and strokes in young children. The mutation leads to dysfunctional smooth muscle cells in arteries, resulting in blockages and increased risk of stroke. Understanding this mechanism could lead to new treatments for moyamoya disease.
Researchers found that the OsMATL2 gene triggers haploid induction when inactivated, resulting in plants with half the normal chromosome number and reduced seed setting. This discovery could revolutionize rice cultivation by accelerating breeding processes.
A study led by University College London researchers analyzed 393 wasp samples collected from citizen scientists and found a single population of the Common Wasp (Vespula vulgaris) across Britain. The findings demonstrate the wasp's ability to disperse itself widely, contributing to its success in human-modified environments.