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The genetic heritage of our extinct ancestors

Researchers discovered a 40,000-year-old gene flow event between an extinct gorilla ghost population and the common ancestor of eastern lowland gorillas and mountain gorillas. This exchange introduced genes that are still present in today's eastern gorillas, including a bitter taste receptor gene under positive selection.

SourceUniversity of Vienna·JournalNature Ecology & Evolution·DateJul 27, 2023

Researchers uncover how a genetic mutation can cause individuals with normal cholesterol levels to develop coronary artery disease at a young age

A novel molecular pathway has been identified, explaining how a mutation in the ACTA2 gene can cause individuals in their 30s with normal cholesterol levels to develop coronary artery disease. The mutation leads to stress in smooth muscle cells, triggering the production of excess cholesterol and driving atherosclerotic plaque formation.

SourceUniversity of Texas Health Science Center at Houston·JournalEuropean Heart Journal·DateJul 7, 2023

Honey bees more faithful to their flower patches than bumble bees

A study by US Department of Agriculture scientists found that honey bees are more faithful to their flower patches than bumble bees. Honey bees returned to 76% of the same alfalfa flowers, while bumble bees visited only 47%. The difference may be due to honey bees' communication system and risk aversion.

SourceUS Department of Agriculture - Agricultural Research Service·JournalEcosphere·TypeObservational study·DateJun 29, 2023

Study reveals genetic signatures of chickpea's cultural crossroads

A new study sheds light on the genetic heritage of chickpeas by analyzing landrace genomics from over 400 specimens collected in the 1920s and 1930s. The research reveals that the spread of chickpeas within each region occurred predominantly along trade routes, rather than through simple diffusion.

SourceSMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution)·JournalMolecular Biology and Evolution·TypeObservational study·DateJun 23, 2023

Mutant KRAS regulates Y chromosome gene in colorectal cancer, driving metastasis and inhibiting anti-tumor immunity

A preclinical study has uncovered the role of Y chromosome gene KDM5D in regulating anti-tumor immune responses and promoting metastasis in male patients with KRAS-mutated colorectal cancer. The study reveals that mutant KRAS drives upregulation of KDM5D, leading to reduced cell adhesion and immune recognition by the immune system.

Masai giraffes more endangered than previously thought

Researchers found that giraffes on either side of the rift have not interbred for over 1,000 years, with females showing no signs of migration. The study suggests that Masai giraffes are more endangered than previously thought, requiring separate but coordinated conservation efforts.

SourcePenn State·JournalEcology and Evolution·DateJun 12, 2023

Human ancestry has been shaped by mixing and matching alleles

Recent studies reveal complex patterns of admixture in human populations, particularly in Africa and the Americas. In Africa, ancient introgression from Neanderthals and Denisovans contributed to increased genetic diversity, while in the Americas, modern admixture resulted in redistributed archaic ancestry.

SourceSMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution)·JournalGenome Biology and Evolution·TypeObservational study·DateMay 19, 2023

A new understanding of human origins in Africa

A recent study published in Nature challenges traditional views on human origins in Africa, proposing that modern humans emerged from the interaction of multiple populations across the continent. By analyzing genomic data from diverse African groups, researchers found evidence of gene flow and mixing over hundreds of thousands of years.

SourceMcGill University·JournalNature·TypeComputational simulation/modeling·DateMay 17, 2023

Genomic analysis shows the Amazon’s Ashaninka people are made up of two subgroups with distinct histories

A recent genomic study identifies two genetically distinct Ashaninka subgroups, suggesting a complex history of interactions with neighboring populations. The research also hints at a possible migration from southeastern South America or the Southern Cone, shedding new light on the genetic origins of this Indigenous group.

SourceCell Press·JournalCurrent Biology·TypeExperimental study·DateMar 16, 2023

What crocodile DNA reveals about the Ice Age

Researchers from McGill University found that changes in sea levels during the Ice Age affected crocodile gene flow, isolating Caribbean and Pacific populations with distinct genetic mutations. The study reveals the resilience of American crocodiles to climate swings and highlights the need for targeted conservation efforts in Panama.

SourceMcGill University·JournalEvolution·TypeData/statistical analysis·DateJan 25, 2023

Ancient Siberian genomes reveal genetic backflow from North America across the Bering Sea

Researchers analyzed ancient genomes from ten individuals up to 7,500 years old in Siberia, revealing a previously unknown hunter-gatherer population that contributed to many contemporaneous and subsequent populations across North Asia. The genetic data show a mix of paleo-Siberian and Ancient North Eurasian people, with links to hunte...

SourceCell Press·JournalCurrent Biology·TypeExperimental study·DateJan 12, 2023

Daylong wastewater samples yield surprises

Composite wastewater samples taken over 24 hours reveal a more accurate representation of antibiotic-resistant genes, with levels 10 times higher than 'snapshots'. Chlorination can negatively impact water quality, highlighting the need for improved treatment protocols.

SourceRice University·JournalACS ES&T Water·TypeExperimental study·DateDec 19, 2022

Guiding conservation with local touch

A group of biologists is exploring the potential of seed banks, frozen zoos, gene editing, and assisted gene flow to create second chances for species affected by climate change. By understanding local adaptation strategies, conservationists can design more effective conservation actions.

SourceMichigan State University·JournalBioScience·DateDec 5, 2022

Ancient DNA analysis sheds light on the early peopling of South America

Researchers used DNA from two ancient human individuals to unravel the deep demographic history of South America, providing new genetic evidence supporting existing archaeological data. They also discovered migrations along the Atlantic coast for the first time and found evidence of Neanderthal ancestry within ancient genomes.

SourceFlorida Atlantic University·JournalProceedings of the Royal Society B Biological Sciences·TypeComputational simulation/modeling·DateNov 1, 2022

Weedy rice has become herbicide resistant through rapid evolution

Scientists found that weedy rice has developed herbicide resistance through gene flow from crop rice, with most fields showing resistant plants within 20 years of herbicide-resistant rice cultivation. This rapid evolution is due to the close proximity of weedy and crop rice in the same fields, allowing for pollen transfer and outcrossing.

SourceWashington University in St. Louis·JournalCommunications Biology·TypeExperimental study·DateSep 8, 2022

A link between early maturation and better aerobic performance identified in juvenile salmon

A study at the University of Helsinki identified a link between early sexual maturation and improved aerobic performance in juvenile salmon. Genetic variations associated with early maturity were found to enhance basal metabolism and energy production, leading to better overall performance.

SourceUniversity of Helsinki·JournalProceedings of the Royal Society of London B Biological Sciences·DateJan 28, 2022

Ancient DNA rewrites early Japanese history -- modern day populations have tripartite genetic origin

New study finds that modern Japanese populations have a tripartite genetic origin, with contributions from Jomon hunter-gatherers, Yayoi farmers, and Kofun peoples. The analysis reveals a complex history of population dynamics, including assimilation rather than replacement during the agricultural transition.

SourceTrinity College Dublin·JournalScience Advances·TypeData/statistical analysis·DateSep 17, 2021

Beavers are well established and moving through the Oregon Coast Range, study finds

A new study from Oregon State University and the U.S. Department of Agriculture's National Wildlife Research Center found that beavers in the Coast Range of western Oregon exhibit relatively strong genetic differentiation, shaped by watershed boundaries and past relocations. The researchers recommend relocating beavers within watershed...

SourceOregon State University·JournalJournal of Wildlife Management·DateAug 30, 2021

Elephant genetics guide conservation

African elephants in Tanzania show limited gene flow between protected areas, highlighting the importance of preserving wildlife corridors for conservation. The study found that some areas, like Lake Manyara and Ngorongoro Conservation Area, were once connected but now have limited genetic exchange.

Swedish, Finnish and Russian wolves closely related

New research at Uppsala University reveals Swedish, Finnish and Russian wolves share a common genetic constitution, indicating a virtually pure origin from Finland and Russia. Genetic analysis of over 200 wolf samples found no evidence of hybridization with dogs in the Fennoscandian wolf population.

SourceUppsala University·JournalEvolutionary Applications·DateNov 10, 2020

New insights into genetic basis of bird migration

Researchers identify VPS13A gene associated with migratory behavior in golden-winged and blue-winged warblers, shedding light on the complex genetic factors behind bird migration. The study's findings may have important conservation implications for declining populations of these species.

SourcePenn State·JournalProceedings of the National Academy of Sciences·DateAug 28, 2019

Fragmented turtles

Scientists studied the impact of fragmentation on Dahl's toad headed turtle populations in Colombia, finding restricted gene flow and genetic erosion. They recommend gene flow restoration via genetic rescue to counteract these threats and provide guidance for this strategy.

SourceWildlife Conservation Society·JournalMolecular Ecology·DateMay 9, 2019