A retrospective cohort study found that sodium-glucose cotransporter 2 inhibitors (SGLT2i) significantly reduced the risk of end-stage renal disease, obstructive airway disease, and pneumonia in patients with type 2 diabetes. SGLT2i may be a better alternative to dipeptidyl peptidase-4 inhibitors for extra-glycaemic protection.
Researchers at the University of Bath developed a new theory that unifies conflicting viewpoints on lane formation, predicting curved and straight lanes in crowded spaces. The study reveals a new class of structures in daily life that may go unnoticed.
A new statistical model based on a global database of public reports can identify an earthquake as high- or low-impact within minutes. The researchers used over 1.5 million felt reports from 10,000 earthquakes to develop the model, which was able to provide impact results for 393 global events in 10 minutes.
A comprehensive study has identified key early-life factors that negatively affect lung function in young adults. The research analyzed data from over 7,500 participants and found that factors such as mother's weight during pregnancy, birthweight, and body composition at primary school have a significant impact on lung health.
Researchers explore cellular senescence's complex relationship with growth stimulation and cell cycle arrest, revealing potential anti-aging drug targets. Understanding these mechanisms is crucial for developing new treatments for age-related diseases.
A study found 38% of children in a rural Mississippi Delta community had parasitic worms or protist infections. This is a neglected health issue in low-resource areas, linked to poor sanitation and climate change. The researcher emphasizes the need for direct community engagement and investment in infrastructure to address these issues.
A new study found that neutral maternal behavior at 12 months correlates with an epigenetic change in children related to stress response. The researchers analyzed data from a cohort of mother-infant pairs and found a small increase in methylation on the NR3C1 gene, which regulates the body's response to stress.
Scientists at RMIT University and partner organisation confirm electric control of superconductivity and giant anomalous Hall effect in the kagome metal CsV₃Sb₅. Proton intercalation modulates carrier density, allowing for tuning of Fermi surfaces and potentially realizing exotic quantum phase transitions.
Researchers estimate worldwide changes in plant leaf growth due to global warming, finding that greening trends have a stronger association with carbon uptake than growing season length. Satellite imagery and field sensors reveal new insights into the impact of climate change on vegetation productivity and carbon capture.
Researchers found that televised debates have little effect on voter decisions, with information from other sources such as media and activists being more influential. Voter choice consistency increased by 17 percentage points over the last two months of campaigns, affecting electoral results.
A new study from McGill University found that individuals with lower education levels are more likely to contract HIV. Researchers also discovered that people living in unstable housing conditions or those who did not complete post-secondary studies were at a higher risk of infection.
A new study reveals that boreal fires contributed 23% of global fire carbon dioxide emissions in 2021, surpassing previous records. The research suggests a link between extensive boreal fires and climate drivers, such as temperature increases and heatwaves.
The new Biohub in Chicago will focus on engineering technologies to study and measure human biology using embedded sensors. Scientists will aim to understand inflammation and develop treatments for diseases such as cancer, heart disease, and Alzheimer's.
Researchers at Oregon State University have developed a dual-purpose catalyst that can both purify herbicide-tainted water and produce hydrogen. The catalyst, derived from metal-organic frameworks, shows promise in tackling global water pollution and provides a sustainable alternative to conventional hydrogen production methods.
Researchers discovered that administration of GDF11 improves cognitive abilities and reduces depression-like behaviors in aged mice. In humans, low levels of GDF11 are associated with depressive episodes, suggesting a potential link between the protein and mood disorders.
A study from Ohio State University reveals stark differences in avian functional diversity between the US East and West. Functional diversity patterns are highest in the West during breeding season, while in the East they are lowest despite high species richness.
A team of Purdue University scientists has identified a protein that plays a key role in helping petunias emit volatiles, challenging the idea that simple diffusion is responsible. The study focuses on how volatiles cross the cell wall, a barrier that separates the cellular interior from the plant's outermost protective layer.
A recent study by researchers at the University of Texas at Austin found that the ocean's ability to absorb CO2 will peak by 2100 and become less efficient after 2300 due to a surface layer of low-alkalinity water. This emergence hinders CO2 absorption, leading to faster warming.
The University of Missouri will receive a $10 million grant from the USDA National Institute of Food and Agriculture to double cover crop seed production in the US by 2030. The project aims to educate farmers about new varieties of cover crops, examine their performance with root growth, and distribute them nationwide.
Researchers created a novel approach to deliver anti-cancer drugs directly to brain tumor sites in children, targeting specific locations while sparing normal brain regions. This targeted delivery method enhances the efficacy of existing treatments and reduces adverse side effects.
Researchers at Reichman University have developed a new sound navigation technology that activates visual navigation areas in the brain, challenging conventional beliefs about sensory processing. This breakthrough has significant implications for cognitive training and potentially detecting Alzheimer's disease.
A review of gene editing techniques suggests that the CRISPR/Cas method could be a game-changer for rice crops threatened by climate change and high food demand. The study highlights its efficiency in improving yield, tolerance to biotic and abiotic stresses, and grain quality.
A study of over 350 former NFL players found that those who reported concussion symptoms performed worse on cognitive tests, particularly in episodic memory and sustained attention. Cognitive decline was not associated with diagnosed concussions or age, but rather with the presence of concussion symptoms.
Researchers at Rockefeller University have found queen-like mutants among social parasite ants, which can infiltrate and take over host colonies. These unique ants exhibit intermediate traits between worker and queen behavior, allowing them to thrive in the colony while avoiding dangers associated with leaving their nest.
A Kingston University student has highlighted the importance of school nurses in addressing the rising number of eating disorders among children and young people. Research and clinical experience have shown that there is an urgent need for early intervention, prevention, and accessibility to help young people living with eating disorders.
A new method developed by Stanford researchers uses an inkjet printer, nanoparticles, and artificial intelligence to detect bacteria in blood, wastewater, and other fluids. The test can be done in minutes, is inexpensive, and more accurate than traditional culturing methods.
A Rutgers study found that 58.3% of US firearm owners store at least one gun unlocked and hidden, while 32.4% use gun safes as their primary lock method. The study suggests that addressing fears about home invasions and educating the public on firearm risks can increase secure storage practices.
A team of researchers at Tohoku University has developed an artificial intelligence-driven contact control system to minimize friction between moving parts in machinery, aiming to reduce wear and tear and extend lifespan.
Researchers at the University of Sussex have developed biodegradable health sensors using natural ingredients like rock salt, water, and seaweed, combined with graphene. These sensors outperform existing synthetic alternatives in terms of sensitivity, making them highly effective for monitoring vital signs.
Researchers from City University of Hong Kong developed a unified colour system based on prime numbers, called C<sub>235</sub>, which can represent various colours more efficiently than existing systems like RGB and CMYK. The new colour system has potential applications in designing energy-saving LCD systems and colourizing DNA codons.
Researchers tracked the lifecycle and function of tingible body macrophages, specialized cells that clean up the immune system's waste, in a significant breakthrough. The study sheds light on autoimmune disorders like lupus by understanding the role of these cells in triggering autoimmunity.
Researchers discovered a new personalized immunotherapy combination that treats aggressive forms of advanced prostate cancer. By blocking PD-1-expressing macrophages and Wnt/β-catenin pathway activation, the therapy significantly improves response rates in PTEN-deficient cancers.
The March issues of The American Journal of Psychiatry and Psychiatric Services focus on major depression treatment advances and suicide risk screening for Indigenous populations. Journalists can access the publications by emailing press@psych.org.
Research reveals obesity increases risk of diabetes and hypertension more significantly in women, with weight loss effective in reducing disease risk. However, merely losing weight is insufficient for reducing dyslipidemia in women, highlighting the need for lifestyle improvement guidance and treatment.
The study confirms the helical coiling of condensed metaphase chromosomes, a concept that has been debated for decades. Researchers used multiple experimental approaches to validate the existence of chromonema coiling in barley and propose a general mechanism for chromosome condensation.
The study resulted in 33 terms that will aid in cider quality communication. Researchers grouped the terms into four categories: rich, fruity, sour, and funky. This lexicon will help producers describe their products with precision and clarity, benefiting both the industry and consumers.
Researchers analyzed chemical isotopes in 1002 skin samples to study the distribution of southern right whales and long-term environmental changes in the Southern Ocean. The study shows that the whales' foraging grounds have shifted, reflecting changing prey distributions, and that climate change has driven recent shifts.
Researchers found that Americans are more receptive to counter-partisan messages than previously thought, and party loyalty does not significantly distort their processing of evidence. The study used a survey of over 5,000 partisans to test the effect of persuasive messaging on their attitudes.
A genomic study of 180 indigenous Africans provides new insights into human history, biology, and population diversity. The research sheds light on the origin of modern humans, African population history, and local adaptation, including traits such as skin color, heart development, and immunity.
Researchers at Chalmers University of Technology developed a method to predict fall accidents and cognitive illnesses like Alzheimer's disease using radar sensors that track walking patterns. The technology can help healthcare staff make more reliable risk assessments and tailor interventions for improved patient outcomes.
A new study reveals that toothed whales have evolved an air-driven nasal sound production system that operates at different vocal registers. This innovation allows them to produce echolocation calls with remarkable efficiency and access the richest food niches in the deep ocean.
A new study from WashU Medicine identified a possible treatment strategy for poikiloderma with neutropenia, a rare bone marrow failure syndrome. Researchers found that inhibiting an enzyme called PAPD5 can restore normal blood cell formation by stabilizing microRNA molecules.
Researchers aim to capture CO2 from industrial emissions and store it in mineralized form in 3D-printed building materials. The project seeks to significantly reduce the carbon footprint of cement-based construction materials.
A study reports successful nonsurgical correction of congenital ear malformations in infants using a custom-made splint made from paper clips. The best results were achieved when treatment was initiated before six months of age.
Consciousness in animals may be more nuanced than previously thought. Researchers at Ruhr-University Bochum suggest ten dimensions of consciousness that cannot be ranked. Strong indicators include complex perception and episodic memory, while weak indicators are simple sensory processing and categorization abilities.
More than two million Europeans contributed to renewable energy initiatives, installing 7.2-9.9 GW worth of facilities and promoting behavioral change. The collective effort produced enough electricity for 8,500-11,700 kWh per person, covering a typical European household's needs.
A Scripps Research and eMed study found that COVID-19 rebound cases are more common than previously reported, affecting up to 14.2% of Paxlovid-treated patients and 9.3% of untreated patients. Rebound is measured by positive test results or symptom recurrence after initial clearance.
A digital food voucher system in Indonesia has significantly increased the frequency with which poor households receive their full allocation of food, from 24% to 81%. The program's success was achieved by replacing traditional rice-bag delivery with digital card vouchers, allowing recipients to purchase food themselves.
The study confirms mid-Tertiary uplifting of the NE Tibetan plateau, with surface uplift and broad planation in the Hoh Xil and West Qinling regions. Small-scale edge-driven mantle convection is proposed as a mechanism for this process.
A new CABI-led study suggests that biopesticides are more effective and environmentally friendly than chemical pesticides for controlling the fall armyworm. The researchers found that untreated plots showed higher larval density and plant damage, while biopesticide treatments showed lower parasitism rates.
Researchers detected 16 security vulnerabilities in DJI drones, including the ability to change serial numbers, override tracking mechanisms, and crash flying drones mid-air. The DJI Mini 2, Air 2, and Mavic 3 models were found to have four severe flaws.
A study finds that the 'classic triad' of meningitis symptoms - fever, altered mental state, and neck stiffness - are rare in both children and adults. The research highlights the need to improve symptom questioning to reduce treatment delays and improve outcomes for patients with bacterial meningitis.
Researchers found that gut microbes drive the production of regulatory T cells, which act as immune healers that repair muscle injury. These cells were previously thought to be only produced in the gut, but now it's clear they also play a role in healing damaged livers.
The DART mission observed a 33-minute change in the orbit of Dimorphos, indicating that ejecta escaped the system and contributed to the orbital changes. The team will use this data to understand how the entire system's orbit changes over time.
A Boston University-led study found that Black women who reported experiencing interpersonal racism in employment, housing, and police interactions had a 26% higher risk of coronary heart disease. Racism has a real impact on the heart health of Black women, increasing blood pressure and inflammation.
Despite calls to expand outpatient surgery, only a small subset of operations took advantage of this approach during the pandemic. Researchers recommend further studies to explore potential barriers to adoption, particularly for safe procedures performed in an outpatient setting.
TUS researchers develop novel method to create multi-walled CNT wiring on plastic films under ambient conditions, enabling flexible devices and energy conversion devices. The proposed method produces high-quality wires with varying resistance values.
Researchers have found that long-tailed macaques reject inferior rewards more frequently when provided by a human than an automatic feeder, indicating social disappointment. This behavioral pattern is consistent with frustration towards the experimenter's decision, rather than a comparison of rewards with conspecifics.
Researchers identified a type of immune cell called age-associated B cells as key drivers of lupus disease. Targeting these cells in a mouse model reduced disease progression, suggesting a potential new therapy for lupus patients.
Two studies found that adults with high cardiovascular health scores tend to live longer lives free of major chronic diseases. The research highlights the importance of maintaining ideal cardiovascular health to delay onset of age-related diseases, allowing individuals to enjoy life in their years as well as their years in life.
A new AI model developed at the University of British Columbia accurately predicts cancer patient survival using natural language processing to analyze oncologist notes. The model shows over 80% accuracy in predicting six-month, 36-month and 60-month survival rates.
The use of AI is improving diagnostic accuracy for digestive cancers, but challenges in data sharing and standardization hinder its widespread application. Researchers surveyed recent applications of AI to these deadly cancers, finding that AI can automate complex processes and detect patterns not visible to humans.
Primary care physicians recommend screening adolescents and young adults for cyberbullying and social media misuse, citing the need for timely intervention due to underreported incidents. Screening tools like R-OBVQ, CBVS, CABS, and MARC can help identify potential risks.
A POSTECH research team developed a machine learning model that accurately predicts cancer type-specific driver mutations, shedding light on distinct pathological mechanisms across various tumors. The model's performance outperformed current leading methods of detection, with better accuracy and sensitivity.
A study published in AJIC found that EHR-focused interventions reduced unnecessary urine culture orders by 20.9% and 21.6% among patients with indwelling catheters. The interventions included changing the electronic medical record ordering screen to require an indication for the culture.
Active surveillance for managing low-risk prostate cancer is increasing nationally, but wide variation persists across practices and practitioners. The study highlights the need for continued progress to minimize overtreatment and improve the benefit-to-harm ratio of national efforts.
Researchers at Massachusetts General Hospital developed an accurate method for detecting Alzheimer's disease using routinely collected clinical brain images. The AI model detected Alzheimer's disease risk with 90.2% accuracy across five datasets, regardless of age or scanner manufacturer.
Researchers at Carnegie Mellon University have developed a latch control system that enables grasshopping robots to perform efficiently on soft substrates. The team discovered that the latch can not only regulate energy output but also mediate energy transfer between the robot and its environment, leading to improved jump performance.
A UC Irvine-led study found that boreal forest fires in North America and Eurasia released nearly half a gigaton of carbon dioxide in 2021, surpassing annual mean emissions between 2000 and 2020. The increased emissions are linked to climate drivers such as warming temperatures and droughts.
A new study found that walking an additional 500 steps per day was associated with a 14% lower risk of heart disease, stroke or heart failure. This benefit is significant for older adults, as most studies have focused on early-to-midlife adults.
Researchers argue that Earth System Justice is necessary to identify and live within biophysical boundaries. The framework aims to reduce harm to people and nature while ensuring access to resources and minimizing tradeoffs.
A PSU study found that high school students who perceive their math teacher as equitable are more likely to develop a positive math identity. This effect is strongest in racially diverse schools, where students may be more aware of racial biases and stereotypes about math. Equitable teaching can help counteract these biases and promote...
Researchers at Stanford University have developed a novel AI-powered approach to analyzing traumatic brain injury, using artificial intelligence to identify the most accurate model of mechanical stress on the brain. This breakthrough could lead to better understanding of when concussions lead to lasting brain damage and inspire new pro...
The study reveals that nitrogen input stimulates plant primary productivity but decreases microbial activities, while carbon input increases nitrogen fixation and mineralization. This dynamic adjustment of carbon and nitrogen cycles has important implications for modeling ecosystem carbon sequestration under global change.
A Norwegian study found that patients who slept less than six hours or more than nine hours per night were more likely to report infections. Chronic sleep problems also increased the risk of needing antibiotics.
A groundbreaking study found that creating shallow water zones enhances fish populations, while coarse wood bundles have positive effects in selected lakes. The approach has stronger long-term effects than narrow species-focused conservation actions.
Researchers found that patients with greater buildup of fatty plaque deposits in the heart's three largest blood vessels had higher chances of developing serious health issues following surgery. This study suggests using existing chest scans to estimate patients' risk of heart attack or death during major surgeries.
A Swedish study of children's drawings during the COVID-19 pandemic found that young children drew detailed images of illness, death, and cancelled activities. The researchers also discovered a high level of health literacy among the children, showing they understood the virus's characteristics and symptoms.
A detailed and dynamic model of the Earth's surface over the past 100 million years provides a high-resolution understanding of its creation and sediment flow to oceans. The model will help scientists predict future changes and understand ocean chemistry.
A recent study found that resistance training significantly improved muscle strength and reduced inflammation in older adults with sarcopenia. The research, conducted by Brazilian researchers, also showed that physical exercise can improve sleep quality and reduce chronic inflammation.
A new study shows that patients with liver cirrhosis have a lower immune response to COVID-19 vaccines, but this does not affect the vaccines' effectiveness. Age, type of vaccine, and viral hepatitis etiology also play a role in immune responses.
A study published in Brain, Behavior and Immunity found that pregnant women with anxiety have higher levels of cytotoxic T cells and different immune marker activity compared to those without anxiety. This suggests a biological link between anxiety and the immune system during pregnancy and postpartum.
Researchers at Baylor College of Medicine discovered that human norovirus GII.4 invades gastrointestinal cells via an unexpected mechanism involving interactions between viral and human cell surface proteins. The findings provide insight into the viral infection process and highlight unique pathways for developing effective therapeutics.
Researchers at Mayo Clinic found that a dissolvable plug delivering stem cells can heal single-tract fistulas in patients with Crohn's disease. The treatment has shown durable results with minimal side effects, offering hope for patients with refractory perianal fistulas.
Researchers developed DEtail-seq, a novel technique for meiotic DNA double-strand break (DSB) profiling. The method provides high resolution at or near single nucleotide level, revealing novel features of meiotic DSBs in various species.
A warmer climate is causing bumblebee queens to emerge earlier, potentially disrupting the timing of plant-pollinator interactions. This can lead to reduced biodiversity and lower pollination rates, as some species may not have enough food during their flight period.
Researchers at UPF's Center for Brain and Cognition have made significant contributions to advancing brain-computer interface technology. By analyzing the synchronization of alpha band levels between brain regions, they were able to identify lateralized patterns that can be used to control devices in real-time.
The Coalition for Trust in Health & Science aims to enhance trust in the health system through credible information and evidence-based decision-making. The alliance, comprising 50 member organizations, seeks to address real-world health impacts of misinformation and disinformation.
A study by Le Bonheur Hospital found that high-flow nasal cannula (HFNC) treatment for mild to moderate bronchiolitis is associated with longer hospital stays and higher costs. HFNC usage outside intensive care units resulted in increased resource utilization for pediatric bronchiolitis patients.
Researchers discovered a novel sound production system in toothed whales, using their nasal passages to generate complex vocalizations. This unique mechanism allows toothed whales to use different vocal registers for echolocation and social communication, similar to humans and birds.
A group of researchers from Osaka University has shown that the segregated function of a messenger ion (Ca2+) can help improve our sense of smell. The study reveals that Ca2+ signaling plays a crucial role in regulating the amplification and reduction of sensory signals, and its processes are clearly segregated within a tiny structure ...
A team of researchers from Michigan State University has discovered two distinct DNA-PK protein complexes that have different roles in DNA repair. One complex fills in lost information, while the other activates enzymes to remove damaged ends. This finding may lead to new strategies for therapeutic gene editing and cancer diagnostics. ...
Researchers developed functional flax fibers with UV-induced switchable wettability for multipurpose oil-water separation. The fibers exhibited hydrophobicity, which could be switched to hydrophilicity through UV irradiation and recovered upon storage in dark environments.
Researchers at Brigham Young University categorized GIF users into three types: Enthusiasts, Searchers, and Referentialists. Enthusiasts use GIFs to express themselves and impress others, while Searchers enjoy the thrill of finding the perfect GIF for a situation. Referentialists rely on pop culture references to respond to GIFs. Under...
Researchers at Tohoku University found that astrocytes exhibit a stronger acid response during REM sleep in epileptic mice, which may drive specific information processing and generating plasticity. This discovery could lead to the development of a biomarker for epilepsy severity and potentially inform therapeutic strategies.
A new study by the University of Copenhagen found that private forests in Denmark have a significant impact on property values. Forest owners attribute great value to their trees and landscapes, leading to increased quality of life and financial gains.
A review of dozens of studies found a positive association between sugary drinks and weight gain in both adults and children, with increasing SSB intake linked to greater weight gain over time. Limiting SSB consumption is an effective way to prevent age-related weight gain.
The study found that operating temperatures between 70-90°C enhance electrical performance as long as reactant humidity is maintained high. Water diffusivity and electro-osmotic drag improve ion conductivity despite increased current densities.
Researchers at the University of Southampton have demonstrated that a beam of light can be confined to an area 50 times smaller than its own wavelength and even move it at the point of confinement. This breakthrough could lead to advanced manipulation techniques for nanoparticles, biological particles, and microscopic sensors.
A research team led by Prof. Zeinab Abdullah has discovered the molecular mechanism underlying the suppression of T-cell immunity in patients with chronic liver disease. By targeting a single immune receptor, they were able to reconstitute the immune responses to vaccination against Hepatitis B and COVID-19 in these patients.
A new process combining human evaluation and AI optimization produces better designs than fully automated systems or manual approaches. The 'Human-Informed Topology Optimization' method reduces material usage while maintaining strength, and can be applied to various scales and applications.
A newly published study of a stalagmite in Cave of the Mounds, Wisconsin, provides evidence for massive warming events during the last ice age, with temperature swings up to 10C over a decade. The research suggests a possible link between these events and Dansgaard-Oeschger events in Greenland ice cores.
Researchers discovered two domestication events for cultivated wine grapevine in Western Asia and the Caucasus region 11,000 years ago. They also found that wine and table grapes were cultivated at the same time, contrary to previous hypotheses.
Researchers at UBC Okanagan have developed transmission schemes that incorporate reconfigurable intelligent surfaces to serve as reflectors within existing wireless networks. These surfaces can bounce signals to cell phones, improving accuracy and reliability in location services and data speeds.
New research confirms that coastal water pollution transfers to the atmosphere in sea spray aerosol, contaminating air for people inland. Bacteria and chemicals from sewage-polluted Tijuana River are detected in ocean aerosols.
The American Academy of Pediatrics recommends earlier and more intensive treatment of childhood and teen obesity, citing evidence that diet and exercise alone are insufficient. The ASMBS supports this guideline, emphasizing the importance of early diagnosis and treatment for better outcomes.
Researchers found broad similarities in how deaf homesigners and hearing adults describe tool-related events, suggesting universal aspects of human thinking. The study suggests that these similarities reflect the extent to which a tool shapes the object it is being used on.
A University of Gothenburg study of over 37,000 men found that being overweight in childhood and young adulthood significantly increases the risk of venous blood clots later in life. The study also suggests that overweight in puberty has a marked impact on future risks of venous thrombi.
A study from the University of Georgia found that less than half of bald eagle nests in coastal Georgia successfully fledged at least one chick in 2022, a 30% decrease below average. The highly infectious H5N1 avian influenza virus is killing off unprecedented numbers of mating pairs of bald eagles, with the number of infected wild bir...
A research team led by Dr Gary Ying Wai Chan has uncovered a new mechanism that ensures correct DNA segregation in cell division, preventing cancer development. RIF1 and protein phosphatase 1 play a crucial role in resolving ultrafine DNA bridges, which can lead to DNA damage and genome instability if not properly resolved.
Researchers developed a platform for localizing and tracking wireless microdevices in the GI tract, achieving millimeter-scale spatial resolution. The system has potential to revolutionize clinical diagnosis and treatment of GI disorders without invasive procedures or radiation exposure.
A University of Bristol study found that social animals limit individuality to conform with the behaviour of the group. Simple social behavioural rules can drive conformity behaviour in groups, eroding consistent behavioural differences shown by individual animals.
Researchers identified a new mutation in the desmoplakin gene that leads to cardiac disease arrhythmogenic cardiomyopathy (ACM). The mutation affects heart muscle cell connections and ion channel function, highlighting the importance of desmosomes in maintaining healthy heart function.
Researchers used AI to analyze literature describing compounds that enhance mitophagy, a process damaged in Parkinson's disease. Probucol, a cholesterol-lowering drug, was identified as the most effective compound with improved motor function and neuron loss in animal models.
A new approach using nanoparticles has been shown to transport drugs across the blood-brain barrier in mice with medulloblastoma. The nanoparticles target a protein called P-selectin, which binds naturally to cancer cells, and trigger transcytosis to deliver drugs to brain tissue.
Researchers developed synthetic peptide nanonets that selectively entrap bacteria, rendering them vulnerable to antimicrobial components. The nanonets displayed both trapping and killing functionalities, demonstrating potential as an anti-infective strategy.
A research team led by Britney Schmidt deployed an underwater robot, Icefin, to explore the Kamb Ice Stream in Antarctica. The robot's findings reveal unprecedented views of ice, ocean, and sea floor interactions, which can improve models of sea-level rise.