A recent study by Bocconi University found that corruption can have a long-lasting effect on trust in democratic institutions. First-time voters who experienced the Mani Pulite investigation in 1994 were more likely to vote for populist parties and express lower institutional trust even 20 years later. The study highlights the need to ...
Researchers from CSIC successfully mapped Cala Millor's shallow seabed in the Mediterranean using satellite images, highlighting the potential of this methodology in diverse ecosystems. This study contributes to improved coastal monitoring and adaptation measures against global change.
A study analyzing European guidelines found that patients with specific characteristics may benefit from longer-term treatment with multiple blood thinners. High-risk patients experienced higher rates of complications due to blood clotting, emphasizing the need for personalized care.
Researchers analyzed cortisol and cortisone levels in over 6,300 individuals to find a strong link between long-term hair cortisone levels and future cardiovascular disease. People with higher cortisone levels were twice as likely to experience a cardiovascular event, especially those aged 57 or younger.
A new analysis of chronic limb-threatening ischemia (CLTI) treatment outcomes found that surgical revascularization is superior to endovascular treatment in patients with higher comorbidities. The study analyzed a broader clinical population than the BEST-CLI trial and found similar outcome rates for Medicare beneficiaries.
A recent study published in Current Biology found that humidity plays a crucial role in attracting pollinators to plants, alongside scent. The researchers discovered that the weevil responsible for pollinating Zamia furfuracea was equally sensitive to humidity as to scent.
A new database reveals thousands of incidents of primates killed by vehicles on roads over the past 30 years, with most species not at risk but some Endangered and Critically Endangered primates involved. Conservationists urge effective mitigation measures to protect wildlife navigating fragmented habitats.
NERC has invested £25 million in a host of high-risk, high-reward research projects tackling key unanswered questions about our planet. The projects cover geology, atmospheric science, biodiversity and ecology, with research spanning 3-4 years and funding up to £1.3 million.
A RAND Corporation study found that methadone use increased sharply among Medicare Advantage enrollees, creating new treatment rather than displacing other medications. The rate of buprenorphine use also rose, particularly among younger enrollees.
A new study found that the gut microbiota of toddlers at 3.5 years old is predictive of body mass index (BMI) at age 5, with certain types of bacteria associated with a higher or lower risk of obesity. The research also suggests that changes in the gut microbiota begin in early childhood and can influence weight gain later in life.
A multicentre, one-year real-world study found semaglutide effective for weight loss in patients with overweight and obesity, with 82% losing over 5% body weight. The medication also improved metabolic parameters, including blood pressure and cholesterol levels.
A new approach has been identified that stimulates cells' DNA repair mechanisms to combat fragile X syndrome. By inducing R-loops and triggering repair mechanisms, the expanded CGG repeat is excised, enabling cells to re-express the crucial FMR1 gene.
Researchers at Tokyo Institute of Technology have successfully synthesized high-quality Cs3Cu2I5 thin films using a novel solid-state synthesis method. The team discovered that depositing CuI and CsI layers in specific ratios results in distinct local structures containing point defects, leading to highly efficient emissions.
Researchers discovered a specific form of ubiquitin protein selectively involved in forming fear memories in female brains, providing a potential target for therapeutic treatments. The finding could lead to more effective treatment options for post-traumatic stress disorder (PTSD) in females.
A recent study by Carolyn Elya reveals the molecular mechanisms behind summiting behavior in infected fruit flies. The researchers discovered that hormonal axes mediate this behavior, and that fungal cells invade the fly's brains during summiting.
A large-scale study found that patients with pulmonary embolism treated with mechanical thrombectomy showed significant improvement in symptoms, quality of life, and cardiac functions. Long-term data also suggested low mortality rates following treatment with the FlowTriever System.
A laboratory study found that exposure to background traffic noise, even at 40 dB, significantly impairs concentration and perceived workload. Researchers also highlight the difficulties in avoiding high-frequency noise indoors due to reduced vehicle speeds.
Current global methane emissions policies are inadequate, covering only 13% of emissions, and are often based on inaccurate data. Stronger social support and political consensus are needed for effective methane mitigation to slow down climate change and improve air quality.
Three Amazonian Morpho butterfly species have been sequenced for the first time, revealing genetic differences that maintain reproductive isolation despite sympatry. The study found Z-chromosome rearrangements and genetic divergence among gene copies, suggesting a role in speciation.
Researchers at Nagoya University have developed a new technology to fabricate high-quality nanosheet films in about one minute. The method uses an automated film-forming process that produces neatly tiled monolayer films with no gaps between the nanosheets.
Researchers have identified the oldest known true-to-scale construction plans in human history, dating back 8,000 to 9,000 years. The ancient engravings depict so-called desert dragons, kilometre-long megastructures used for trapping animals.
A large case-control surveillance study of over 100,000 pregnancies found COVID-19 booster vaccination not associated with spontaneous abortion. The results support the safety of COVID-19 booster vaccination recommendations for pregnant populations.
A study found that semaglutide use for one year decreases the 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with overweight or obesity. The treatment also leads to significant improvements in metabolic parameters, such as blood pressure, cholesterol, and fasting glucose levels.
A mathematical model developed by researchers at the University of Michigan could help engineers control the behavior of vortex rings in nuclear fusion and other applications. Vortex rings form during fuel compression and can disrupt the efficiency of fusion reactions. The model, which draws parallels with smoke rings, aims to understa...
A study found that expert mammogram radiologists exhibit visual hindsight bias, leading to improved performance on blurry images after prior clear images were viewed. This bias can impact the detection of lesions and has implications for negligence lawsuits and patient outcomes.
The study aims to identify triggers and modifying factors modulating real-life loss and regaining of control over drug use, as well as neurobiological mechanisms involved. The research focuses on age, gender, physical activity, and cognitive control.
Researchers at University of Toronto Engineering have developed a sustainable solution to remove phosphate and ammonium from wastewater by utilizing advanced membranes incorporating inorganic particles. This method recovers these nutrients for future use, providing a new source of materials for agricultural fertilizers and helping addr...
Researchers analyzed data from over 100,000 pregnancies and found no association between COVID-19 booster vaccination and increased miscarriage risk. The study adds to the growing understanding of the safety of COVID-19 booster vaccinations during early pregnancy.
Scientists at Temple University have developed a novel gene-editing strategy that disrupts the ability of HIV-1 virus to enter host cells by targeting a rare genetic disorder. This approach may offer another target for developing next-generation CRISPR technology for HIV elimination, while avoiding adverse effects on cell mortality.
A University of Leicester-led study suggests that ancient lakes existed in South Africa's interior during the last Ice Age, supporting hunter-gatherer communities. The research provides new insights into human migration patterns and ecosystem sensitivity to global climate change.
Researchers at Massachusetts General Hospital found that treatment with the BCG vaccine was associated with a 20% lower risk of Alzheimer's disease and related dementias. The protective association was greater in patients aged 70 years or older.
Illinois Tech researchers found that blockchain technology, investor sentiment, and economic stress are key predictors of bitcoin returns. Bitcoin's detachment from economic fundamentals makes it a poor safe-haven asset.
Teenagers living with obesity who experience uncontrolled hunger are more likely to perceive their weight as negative, worried about its health effects, and actively trying to lose weight. They also report greater dissatisfaction with their body image and higher rates of bullying.
Researchers from Rice University and Baylor College of Medicine are developing a new 'glyco-immune' checkpoint inhibitor to train the immune system to target and kill breast cancer metastasis in bones. The therapy has shown promise in preliminary tests, including eradicating cancer in some animals.
Researchers develop a novel wavelength-selective intelligent colloid system that achieves light-controlled multi-dimensional phase segregation, enabling the creation of programmable photochromic ink for various applications. The system relies on rearranging existing pigments rather than generating new chromophores.
A new study suggests that a business's long-term success depends on its founding conditions, rather than changing market environments. Businesses founded in dynamic environments with functionally diverse teams tend to survive environmental change through slower decision-making and increased creativity.
A new study from UC San Diego shows that noninvasive brain imaging can distinguish among hand gestures with more than 85% accuracy. The research uses magnetoencephalography (MEG) to detect magnetic fields produced by neuronal electric currents, offering a safe and accurate option for developing brain-computer interfaces.
A survey study found that fewer than 1 in 10 vaccinated individuals received an incentive, with most reporting no change in their decision to get vaccinated. The study suggests that policy efforts to incentivize vaccination may be ineffective.
New Jersey's Medicaid reforms led to a significant increase in buprenorphine prescriptions for opioid addiction treatment, outpacing national rates. The reforms reduced barriers to medication usage among poor patients, resulting in slower growth of overdose deaths nationwide.
Researchers discovered that FDA-approved HDAC-inhibitors can impact energy metabolism in solid tumor cells, including glioblastoma. The combination of HDAC-inhibitors and imipridones may synergize to enhance killing of GBM cells by reversing cellular respiration.
A molecular epigenetic mechanism, common to many species, mediates long-term cellular responses to particulate matter such as air pollution. This discovery offers a promising step towards understanding the impacts of nanoparticle exposure on biological systems and the environment.
A new study published in Strategic Management Journal found that evaluators separate ideas from proposers, suggesting that hiding the identity of idea proposers may not improve evaluation. The researchers tested three potential biases and replicated their findings with a larger sample size.
Mosquitoes use human body odor to find hosts over long distances, with specific airborne components making some people more attractive than others. Researchers found that carboxylic acids and eucalyptol are key contributors to this attraction, with varying levels affecting mosquito choosiness.
Researchers at Flinders University have discovered a new way to make 'green' polymers from low-cost building blocks using just a small amount of electricity. The reaction is fast, occurs at room temperature, and can be recycled into its constituent building blocks in high yield.
Researchers used a machine-learning method to identify sex-specific genes and molecular pathways contributing to Alzheimer's disease progression. The study found that females experience faster cognitive decline, while males have greater mortality rates.
Recent studies reveal complex patterns of admixture in human populations, particularly in Africa and the Americas. In Africa, ancient introgression from Neanderthals and Denisovans contributed to increased genetic diversity, while in the Americas, modern admixture resulted in redistributed archaic ancestry.
The Society for Cardiovascular Angiography and Interventions (SCAI) has awarded Early Career Research Grants to two junior interventional cardiologists, Nadia Sutton and Eric Secemsky. Their projects focus on high-priority topics in cardiovascular disease, including coronary microvascular dysfunction and peripheral vascular interventions.
Biophysicists have created an artificial transport system that maintains liposomes in constant motion using protein patterns and ATP. Two possible mechanisms for this motion are proposed, involving zipper-like interactions or membrane deformation.
A decision analytical model found that increased uptake of bivalent booster vaccination among eligible age groups decreased pediatric hospitalizations and school absenteeism. The benefits of booster campaigns for children may be substantial, suggesting a focus on younger populations is crucial.
Researchers found that the brain's auditory cortex responds strongly to positive human sounds coming from the left, but not from the right or front. This bias may have an evolutionary advantage, as it could help detect potential threats or predators.
A new study by Penn State researchers found that some climate mitigation strategies could result in harmful health impacts in specific areas, particularly if significant land use changes are required for bioenergy production. This could lead to worsened respiratory and cardiovascular diseases, resulting in premature deaths.
Only 13% of global methane emissions are regulated, despite causing at least 25% of current global warming. The lack of regulation and clarity must be urgently addressed to meet global climate targets, with a consistent approach worldwide needed to drastically reduce global warming levels.
A new study by UC Davis MIND Institute researchers and others finds that the M-CHAT-R/F screening tool is effective in identifying children with autistic traits, but it also flags many children incorrectly. The study highlights the need for clinical judgment and clear communication with parents about the limitations of the tool.
The next-generation Evolut FX TAVR system shows improved deliverability, tracking, and deployment compared to its predecessor. This is particularly beneficial for patients with difficult anatomies, where the new device's predictable deployment can improve coronary access, blood flow, and valve performance.
A study found that over half of English NSCLC patients living in low-socio-economic areas did not receive new anti-cancer therapies, despite having access to free treatment through the National Health Service. The researchers examined data from 90,785 patients diagnosed between 2012 and 2017.
This field uses trial-and-error learning with natural selection to solve complex reinforcement learning tasks, but requires significant computational resources. Researchers can enhance its efficiency by improving encoding, sampling, search operators, algorithmic frameworks, and evaluation methods.
Researchers have developed a novel tin-based MOF that can selectively reduce CO2 to formate in the presence of visible light, achieving high selectivity and quantum yield. The material, called KGF-10, was found to be efficient, precious-metal-free, and single-component.
The TWILIGHT trial found ticagrelor monotherapy after PCI to have a similar risk of repeat revascularization and MACCE compared to dual antiplatelet therapy. Ticagrelor monotherapy was also associated with lower NACE and clinically-driven revascularization risk.
A new analysis of COVID-19 patients with heart attacks reveals increased clotting in coronary arteries before and after treatment. High TGB was observed in 74% of patients pre-intervention and 29% post intervention.
A team of astronomers has observed the most luminous quasar in 9 billion years, shedding light on its interaction with its environment. The study found that the quasar's black hole is growing at a rate of 100 solar masses per year and emitting powerful winds into the host galaxy.
Researchers have identified three subtypes of ovarian high-grade serous carcinoma (HGSC) based on genomic changes, which may help tailor therapies. The study's findings could improve treatment outcomes for patients with this aggressive subtype.
Researchers found that 78% of patients reported at least one social risk factor impacting their health. A chatbot was developed to provide follow-up outreach and deliver educational content to recently discharged birthing individuals.
A recent study published in The Lancet Neurology found that valbenazine significantly reduces chorea symptoms in patients with Huntington’s disease. The Phase III trial showed improvement as early as the second week of treatment, with consistently greater benefits compared to a placebo.
A recent study analyzes national greenhouse gas emission inventories, revealing limited accuracy and transparency in low-and-middle-income countries. The review highlights the need for improved reporting methodologies to manage food security and climate change adaptation and mitigation.
The CLIPPER cohort of over 1 million patients found that 1 in 6 died within the first year and 50% survived at five years after diagnosis. The study aims to develop process measures for high-quality care and improve survival rates.