A study found an association between SSRI treatment and violent crime in adults and adolescents, with a significant increase during treated periods. The risk persisted for up to 12 weeks after stopping SSRI treatment, highlighting the need for clinical awareness of this potential side effect.
A Northwestern University-led team has developed a smart sponge that selectively soaks up oil in water, leaving clean water and unaffected marine life behind. The sponge can absorb more than 30 times its weight in oil and can be reused many dozens of times without losing effectiveness.
A new framework published in NEJM offers a responsible approach to patient data-sharing, allowing companies to access massive data troves with transparency and consent. The system includes an easy-to-understand informed consent document and a dedicated gatekeeper committee to review and approve projects.
A new study reveals that most cultural changes in the Near East had no lasting effect on the genetics of local people in Beirut. Only three periods - Iron Age, Alexander the Great's arrival, and Ottoman Empire domination - left a lasting genetic impact.
Researchers at ETH Zurich create implant that uses electrical signals to stimulate insulin production in diabetic mice, offering potential breakthrough for real-time glycemic control. The system is designed to be connected to the internet and controlled via an app, paving the way for a more integrated approach to diabetes management.
Research reveals that age, sex and smoking impact μ-opioid receptor density in brain. Dysfunctions of the brain's opioid system are linked to disorders like addiction and chronic pain.
Researchers developed a new approach to build power-efficient and programmable integrated switching units on a silicon photonics chip. The technology enables bulk fabrication of generic optical circuits that can be programmed for specific applications.
Type 2 diabetes affects American Indians and Alaska Natives at three times the rate of white Americans, linked to higher cardiovascular disease rates. Obesity is prevalent, with 30-40% of American Indians having obesity, which increases risk factors for heart disease.
Research found that physical activity at work may increase risk of neck and back pain, while leisure time activities have a positive effect. A balance between work and rest is key to reducing the risk of disability and impaired quality of life.
A transgenic mouse model of HLH has been found to be effective in treating severe COVID-19 patients by calming the 'cytokine storm', a common feature of children battling secondary HLH. Ruxolitinib showed promising results, with 90% of patients showing CT scan improvement within 14 days.
A comprehensive survey reveals that bacteria are widespread in human tumors, differing by tumor type. Different tumor types harbor distinct microbiomes, with breast tumors displaying a rich and diverse community of bacteria.
Researchers at Temple University Health System have discovered that blocking the molecule Drp1 can prevent abdominal aortic aneurysms from developing in animals. The study suggests that maintaining mitochondrial fission-fusion balance may be fundamental to preventing AAA and other cardiovascular diseases.
A WPI-led research team has identified drugs that target triple-negative breast cancer tumors in mice without inducing toxic side effects. The targeted therapies use molecular recognition units to specifically target the tumors, reducing their sizes and eliminating them.
A public health insurance option could reduce premiums for individuals by 10-27% due to lower provider payment rates. However, its impact on expanding coverage is limited, with only a 3-8% increase in insured individuals under most scenarios.
Researchers at NUTRITION 2020 LIVE ONLINE explored the impact of COVID-19 on Nutrition 2020, which was canceled. The meeting covered various research findings, including the benefits of whole grains for diabetes risk and the dangers of empty calories in children.
A team of researchers from the University of Portsmouth has discovered a unique pterodactyl jaw fragment in Sandown Bay, Isle of Wight, which is remarkably similar to previously found 'tapejarid' fossils in China and Brazil. The specimen, named Wightia declivirostris, lacks teeth and features distinctive sensory organs.
A study by Carnegie Mellon University found that social networks actually worsen decision-making in emergency situations, leading to delayed evacuations and the spread of misinformation. The research suggests that communication within groups does not improve decision-making as expected.
A study of Chinese families found that wearing face masks at home was 79% effective in preventing the spread of COVID-19 among household members before symptoms developed. However, daily contact and certain hygiene practices were associated with an increased risk of transmission.
Researchers at Duke University developed a synthetic molecule that selectively dampens cocaine-induced hyperactivity and interferes with dopamine metabolism in the brain's rewards center. The treatment slowed down drug use by 20 minutes to an hour and reduced consumption by over 80 percent in mice.
Researchers developed a smart window technology that automatically changes color in response to sunlight intensity, reducing the need for power and lowering production costs. This technology can block sunlight and reduce cooling costs in buildings, making it suitable for large commercial buildings and automobiles.
Dr Martin Kerin, an Irish mathematician from NUI Galway, has published a research article in the Annals of Mathematics, resolving a question on the geometry of seven-dimensional exotic spheres. The discovery confirms that all these spaces admit non-negative curvature.
Researchers from the University of Warwick and the University of Waikato found no evidence that Sans Forgetica boosts memory. Four experiments involving over 882 people showed that the font promotes a feeling of disfluency but does not improve learning, contradicting previous claims.
Myeloma Drug Sensitivity Testing (My-DST) uses liquid biopsies to test drug effectiveness on patient samples. The approach shows promise in predicting real patient responses, and may guide drug development for multiple myeloma treatment.
NASA analyzed rainfall generated by post-tropical cyclone Bertha, which brought heavy rain to the Carolinas and Midwest. The GPM core satellite measured rainfall rates of up to 1 inch per hour in south central West Virginia, prompting flash flood watches for several states.
A study found a dramatic surge in hydroxychloroquine/chloroquine prescriptions during the COVID-19 pandemic, with almost half a million excess fills compared to 2019. The surge occurred after March 15 and was likely due to off-label prescribing for COVID-19, raising concerns about safety and efficacy.
A new study by Children's Hospital of Philadelphia researchers found a nearly 2.5-fold decrease in pediatric fractures overall due to cancelled sports and playground closures, but an increase in at-home fractures, particularly bicycle and trampoline injuries.
A Phase II trial led by MD Anderson Cancer Center researchers found that treatment with MK-6482 resulted in a 27.9% objective response rate in patients with von Hippel-Lindau disease-associated renal cell carcinoma, with most side effects being grade 1 or 2. The drug directly targets HIF-2a and has been shown to be well-tolerated.
A new study from the University of Bristol found that users of high-potency cannabis are four times more likely to report associated problems than users of lower-potency strains. The research used data from a long-term health study and controlled for other factors, such as frequency of use and early mental health symptoms.
The CORONADO study found that 1 in 10 COVID-19 patients with diabetes died within 7 days of hospital admission, and 1 in 5 were intubated and mechanically ventilated. Poorer blood sugar control did not impact patient outcomes, but the presence of diabetic complications and increasing age increased mortality risk.
A recent study by Arizona State University's Canine Science Collaboratory found that pet dogs will attempt to rescue their owners if they know how. Approximately one-third of the dogs in the experiment rescued their owners, suggesting that motivation alone is not enough, but rather a combination of understanding and ability are required.
The Hugo Observatory in Belgium coordinates the largest Horizon 2020-funded climate change and migration research project, HABITABLE, worth 6.8 million euros. The project explores how climate change affects migration patterns, introducing a new concept of social tipping points.
Researchers analyzed 73 ancient genomes and found that the Canaanites descended from a mixture of local Neolithic populations and Iranian/Caucasus-related ancestry. This study sheds light on the cultural and genetic similarity among city-states, and how migration from the northeast may have influenced the region's culture.
A study by researchers at the University of Zurich mapped immune cells in different types of brain tumors, revealing tumor-specific instructions for tissue-invasive leukocytes. The findings provide a basis for developing tailored immunotherapies for various types of brain tumors.
Researchers have obtained the structure of the light-sensitive KR2 protein in its active state, revealing the mechanism behind light-driven sodium ion transport. The study provides a detailed understanding of how this protein works and could lead to the development of new optogenetic tools.
Researchers have developed a wearable device that uses external electric fields to trigger insulin release from bioengineered cells, stabilizing blood glucose levels in mice. The approach opens the door for remote-controlled diabetes therapies and represents an expansion of electrogenetic toolboxes for human therapeutics.
Girls with autism experience greater reduction and less rise in symptom severity than boys, according to a UC Davis MIND Institute study. Children's symptoms can change with age, and some may even lose their diagnosis entirely.
Italian healthcare workers experienced high rates of posttraumatic stress disorder, depression, anxiety, and insomnia during the COVID-19 pandemic. The study highlights the need for mental health support for frontline workers.
A new study published in the Disability and Health Journal found that individuals with intellectual and developmental disabilities (IDD) are at a higher risk of dying from COVID-19. The research revealed significantly higher case-fatality rates among those with IDD, particularly among younger age groups.
New study reveals Antarctica's ice sheets retreated at a rate of over 10 kilometers per year, much faster than current rates. High-resolution seafloor mapping allows researchers to uncover the complex history of glacial dynamics and provide insights into past sea-level rise.
Researchers at Radboud University and Uppsala University have discovered a new type of magnetic behavior in neodymium, where atomic spins form patterns that whirl like a helix but constantly change. This phenomenon, known as a self-induced spin glass, could pave the way for new materials for artificial intelligence.
Researchers at Terasaki Institute develop a microneedle patch to extract skin interstitial fluid, providing an alternative source for biomarker testing and overcoming issues with blood sampling. The patch, made of gelatin methacryloyl, is highly absorbent and biocompatible, eliminating the need for hollow needles.
Researchers have developed a novel nanoscale topography that imparts durable antiviral and antibacterial properties to an aluminum alloy, reducing the spread of infections in hospitals. The surface was found to be effective against bacteria and viruses, with most being inactivated within 2-3 hours.
A new study by Carnegie Mellon University researchers has found the brain programs that code the sequence of steps in performing a complex procedure. The main findings were that each knot had a distinctive neural signature, so the researchers could tell which knot was being tied from the sequence of brain images collected.
A new one-minute test developed at Ben-Gurion University can identify asymptomatic and affected carriers of COVID-19 with greater than 90% accuracy. The test kit costs approximately $50, making it less costly than standard PCR tests.
Deep earthquakes can provide vital clues to understanding plate tectonics and the Earth's interior. A new model simulates subduction zones, showing that deformation is a major factor in deep earthquakes.
A study of over 73,000 people in 33 countries found that four out of ten adults worldwide have functional gastrointestinal disorders. The disorders, which include symptoms like heartburn and irritable bowel syndrome, were more prevalent in women and associated with lower quality of life.
Researchers discover how top leisure brands create 'sticky' customer experiences, using rapid entry, endless variation, and sparking new journeys. These chaotic experiences keep customers hooked, making them more eager for monthly subscriptions.
A study by NTU Singapore-Harvard University has identified a promising molecular pair, Prostaglandin E1 and Prostaglandin A1, that can boost dopamine levels and slow Parkinson's disease. The researchers found that these hormone-like substances can activate Nurr1, leading to increased dopamine production and neuroprotection.
A new genomic analysis reveals a decrease in genetic variants associated with ADHD across the human evolutionary lineage. The study suggests that favourable selection may have occurred in ancestral environments, leading to the high prevalence of ADHD in modern populations.
Asymptomatic individuals can spread SARS-CoV-2 via aerosols, highlighting the importance of mask-wearing and physical distancing. Research estimates that a single minute of loud speaking can generate up to 100,000 virion-containing aerosols, which can remain airborne for hours.
Researchers have discovered a new class of immunotherapy that targets myeloid immune cells and slows tumor growth by inhibiting the c-Rel molecule. The treatment showed promising results in both human cells and mouse models, shrinking tumors by up to 80% and reducing immune suppressor cells.
The Chan Zuckerberg Initiative is awarding $3.8 million to support essential open source software projects in biomedical research and clinical medicine. These grants will enable awardees to improve software tools, enhance collaboration, and advance biomedical science.
A UCLA-led study found a significant increase in domestic violence calls to police in Los Angeles and Indianapolis during the COVID-19 pandemic. The researchers predict that the incidence of domestic violence will decrease as people return to normal routines, but may increase again if there is a second wave of COVID-19 infections.
A new study published in the Journal of the American Heart Association finds that palliative care significantly lowers rehospitalization rates and improves patient outcomes for those with heart failure. Palliative care added to standard treatment plans can reduce hospital readmissions by up to 25%.
A recent study reveals that volcanic eruptions in the tropics lead to a decrease in global precipitation, primarily through the amplification of El Niño. The research found that the strength of El Niño is directly related to the magnitude of precipitation reduction.
An exploratory study found that metformin combined with rapamycin was well-tolerated in patients with stable or responding metastatic pancreatic ductal adenocarcinoma (mPDA) after 6 months of chemotherapy. The combination was associated with exceptionally long survival rates and improved disease stability.
Researchers have developed biodegradable polymer fibres infused with nimodipine to prevent nerve cell death after brain surgery. The treatment reduces side effects and minimizes blood pressure risks, offering a promising alternative to intravenous administration.
African American patients who died from COVID-19 had obstructed small vessels and capillaries in the lungs due to blood clots and associated hemorrhage. Elevated D-dimers were also found, but no myocarditis was observed, contradicting early reports suggesting a significant role in death.
Researchers in Ontario, Canada, found that physical distancing measures can prevent COVID-19 resurgence. A systematic review on hydroxychloroquine and chloroquine for treating COVID-19 showed conflicting evidence on their effectiveness.
A team of Rochester Institute of Technology researchers will examine how microplastics accumulate in the lake's ecosystem using mathematical modeling, field surveys, fluid dynamics, genomic sequencing and other experiments. The goal is to inform policy and mitigation strategies for combating microplastic pollution.