The Pancreatic Cancer Research Fund Tissue Bank has been established to provide quality-controlled tissue and fluids for research on pancreatic diseases. The bank holds over 45,000 unique samples, including blood, urine, saliva, and tissue from patients with various types of pancreatic cancer and pancreatitis.
Scientists at Tomsk Polytechnic University discovered that xenon positively affects physicochemical, mechanical and biological properties of calcium phosphate coatings used in oral and maxillofacial surgery, orthopedics, and traumatology. The coatings formed using xenon show better adhesion, which prevents peeling off too quickly.
The COVID-19 pandemic significantly challenges cancer prevention and control in Africa, diverting resources away from cancer patients. However, this crisis also creates opportunities for innovation and improved access to cancer care.
The Asian tiger mosquito Aedes albopictus has been shown to transmit the Zika virus and trigger large outbreaks in a simulated environment. However, experimental studies suggest that the mosquito's infection rate is low, making it unlikely to cause major Zika virus epidemics.
Researchers from St Petersburg University have discovered a complex of rocks forming an ancient island arc in the Songkultau Mountains of Kyrgyzstan, dated to around 500 million years ago. The finding provides valuable insights into the geological history of Central Asia and has implications for understanding large ore deposits.
A novel virtual screening strategy identified pralatrexate as a promising treatment for Covid-19. Lab experiments showed that the chemotherapy medication inhibited viral replication more effectively than remdesivir.
Researchers have created microfabricated elastic diamonds that can stretch up to 10% without losing their shape. This controlled elasticity changes the diamond's electronic properties, including a reduced bandgap, making it suitable for advanced electronics and quantum information technologies.
Researchers from Iowa State University and Penn State University developed a method to measure and model desalination membranes, leading to improved water flow and salt removal. By creating uniform membrane density at the nanoscale, they found that membranes with fewer hot spots perform better.
High aerosol concentrations increase environmental humidity by producing more clouds, which can mix condensed water into the surrounding air. This humidification enhances updraft speeds, intensifying thunderstorms.
Researchers discover new mutations in malaria parasite that enhance resistance to sulfadoxine-pyrimethamine, a key preventive drug. These mutations are already widespread in Africa and Asia, threatening efforts to use the drug to prevent malaria in vulnerable groups.
Desalination membranes' density distribution at the nanoscale is crucial for performance. Thinner membranes with consistent density improve water filtration, contrary to previous thought that thickness matters more. This breakthrough could lead to 30-40% efficiency increase and cost savings.
Researchers identified traditional Ghanaian medicines that work in the lab against schistosomiasis, onchocerciasis, and lymphatic filariasis. Eight extracts showed good activity against these diseases, as well as trypanosomes, which cause other human diseases.
A large randomized clinical trial compared thresholds for blood transfusions in premature babies and found no advantage in survival or neurological impairment. The study, led by Dr. Rosemary Higgins of George Mason University, suggests that current guidelines for blood transfusions may not be optimal.
Preliminary data from the non-powered U.S. Phase 2 study showed that orally-administered opaganib was safe and demonstrated consistent trends of greater improvement in reducing oxygen requirement across key primary and secondary efficacy outcomes. The opaganib-treated arm demonstrated a greater improvement in reaching room air, reducti...
A new study by Ohio State University found that social media posts with matched imagery and text are more effective in recalling safety messages among young parents. Participants spent significantly longer on posts with matched messages, indicating better understanding and recall of safety knowledge.
Active matter systems, which can move under their own power, have been found to spontaneously order without higher-level instructions. Researchers developed a theory that predicts certain types of active matter will enter
Researchers found that combining CAR T cells with a proinflammatory environment created by STING pathway activation can improve their ability to attack tumor cells. This approach, combined with therapeutic antibodies, led to the complete eradication of breast tumors in mice.
A new study suggests that adding a small molecule to CAR-T cell therapy can boost the effectiveness of immunotherapy against breast cancer and other solid tumors. Researchers found that the addition of cGAMP activated an immune response, leading to enhanced T cell proliferation and tumor growth reduction.
Researchers have developed a new method to enhance the sensitivity of quantitative phase imaging, enabling the observation of tiny particles in living cells without labels or stains. The technique, called ADRIFT-QPI, produces images with seven times greater sensitivity than traditional methods.
Two recent studies from Oregon State University found that Oregon's Medicaid expansion led to increased prenatal care among low-income women and improved health outcomes for newborn babies. The expansion resulted in a nearly 2 percentage point increase in first trimester prenatal care utilization.
A new analysis suggests that subsidence, the sinking of ground's surface, will impact 19% of the world's population - 21% of GDP - by 2040. The model identifies areas with high susceptibility to subsidence, particularly in Asia, where 635 million inhabitants are exposed.
Researchers from the University of Texas at Austin and Penn State have developed a new understanding of desalination membranes, which can clean more water while using significantly less energy. The breakthrough could lead to increased access to clean water and lower water bills for individual homes and large users alike.
Researchers have successfully stretched diamond to achieve large, uniform tensile elastic straining, opening up new possibilities for advanced functional devices. The findings suggest the potential of strained diamonds as prime candidates for microelectronics, photonics, and quantum information technologies.
A study published in PLOS Pathogens reveals that mosquitoes feeding on blood multiple times increase malaria transmission potential, shortening the incubation period and making disease control more challenging. The research suggests that younger mosquitoes with reduced reproductive ability may contribute to infection, undermining curre...
Researchers at PPPL and Commonwealth Fusion Systems successfully simulated particle confinement in the SPARC tokamak device, crucial for achieving commercial fusion energy. The study predicts well-confined alpha particles will minimize damage to the facility, paving the way for plasma self-heating and improved techniques for control.
Scientists at UT Southwestern Medical Center have discovered a type of cell responsible for triggering chronic inflammation in fat tissue. The study found that these cells, called fibro-inflammatory progenitors (FIPs), produce signals that encourage inflammation when exposed to high-fat diets.
A study from Cedars-Sinai Medical Center found that people who move due to unaffordable housing are at increased risk of failing to receive necessary medical care, leading to long-term health problems. The research highlights the need for preventive action to mitigate the adverse effects of cost-related moves on healthcare access.
Researchers used tree rings to reconstruct river discharge histories, finding that Asian rivers behave in a coherent pattern with large droughts and pluvial periods often occurring simultaneously. The study's findings have important implications for water management, particularly in countries with multiple river basins.
Researchers found microvascular blood vessel damage and inflammation in brains of patients who died from COVID-19, suggesting a non-infectious response. The study suggests that the body's inflammatory response to SARS-CoV-2 may cause brain damage.
A National Institutes of Health-funded study found that providing a higher threshold of red cells offers no survival benefit for preterm infants and does not reduce neurological impairment. The study used data from 845 infants with varying hemoglobin thresholds to compare outcomes.
The mRNA-1273 vaccine demonstrated effectiveness in preventing severe COVID-19, with no safety concerns or evidence of enhanced respiratory disease. The trial enrolled over 30,000 participants and showed a significant reduction in symptomatic cases among those who received the vaccine.
Researchers at LSU Health New Orleans have discovered a potential new RX strategy for stroke, combining an LSU Health-patented drug with selected DHA derivatives to protect brain cells and increase recovery. The study found that this combination therapy significantly reduced lesion volumes and improved behavioral scores, offering hope ...
A research team studied processing speed deficits in individuals with spinal cord injury (SCI) and found similar brain activation patterns with older healthy individuals. The study suggests that SCI individuals compensate for processing speed deficits by relying on executive control and memory areas of the brain.
A University of Guam study has found that retaining leaves during cycad stem cutting propagation and using anti-transpirant products have no effect on success rates. Healthy cycads can recover from root or leaf loss with proper care.
A UNIGE study found that people who met their partners on dating applications have stronger cohabitation intentions and desires to have children. The results also show that couples formed through apps have diverse socio-educational profiles, leading to increased long-distance relationships.
Scientists have developed a bioinspired material that enhances lithium-ion extraction by controlling interlayer spacing and achieving stable ordered nanostructures. The new membrane shows higher toughness and efficiently controls Li+ permeation rate, outperforming other materials.
In response to the COVID-19 pandemic, trauma centers developed innovative processes to optimize use of personal protective equipment, ICU beds, and ventilators. These measures enabled the provision of critical trauma services while protecting healthcare teams.
Neal Schrick and Hongwei Xin recognized as FSLI Fellows for contributions to food systems leadership. The two UTIA leaders completed the FSLI executive leadership development program, enhancing their skills and perspectives on integrated food systems.
The Moderna COVID-19 vaccine has demonstrated a 94.1 percent efficacy in preventing symptomatic COVID-19 infections and severe illness, according to the results of the ongoing phase 3 clinical trial. The study enrolled over 30,000 participants and found that cases of severe COVID-19 occurred only in those who received the placebo.
A new study by researchers at UCSF and Columbia University highlights the role of frailty in the gender gap in mortality rates for women waiting for liver transplants. Women awaiting liver transplants are found to be more likely to become too ill to undergo surgery or die before receiving a liver, with frailty being a significant risk ...
Scientists found two secondary minima in the potential energy landscape of nickel-64, corresponding to oblate and prolate ellipsoidal shapes. The prolate one is deep and well-isolated, leading to a prolonged trapping time, unlike heavy nuclei.
Researchers review cognitive testing studies and propose using computer simulations to gauge behavioral problems in children with ADHD. The approach aims to provide more information on the complexity of symptoms, enabling clinicians to make life easier for kids with ADHD.
Researchers found the error source of a sea-ice model varies with the season, leading to discrepancies between simulations and observations in both cold and warm seasons. The study suggests using an ensemble approach to consider seasonal variations in model errors, improving future simulation and prediction of Arctic sea ice.
New research from Karolinska Institutet reveals the development of lung macrophages, immune cells that can protect or harm lungs. Classical monocytes migrate into airways and lung tissue, becoming protective macrophages, while non-classical monocytes develop into pro-inflammatory macrophages.
Researchers found that stopping RAS inhibitors reduced the risk of requiring dialysis but increased the risk of cardiovascular events and death. The study suggests that doctors must carefully weigh the benefits and harms of these medications in patients with advanced CKD.
Researchers at Kyoto University's iCeMS have discovered how a transporter protein twists and squeezes compounds out of cells, including chemotherapy drugs from some cancer cells. This mechanism, driven by ATP energy, facilitates the export of toxic compounds and confers drug resistance.
Researchers analyzed five cases of patients with COVID-19 who experienced severe cardiac manifestations, including ST-elevated myocardial infarction (STEMI). NETs were found to form in coronary thrombuses, causing blockage of microvessels and contributing to the development of heart attacks.
Researchers found significant variation in flag leaf ability to adjust to fluctuating light, with some varieties producing carbohydrates nearly twice as fast as others. This discovery could lead to improved water-use efficiency and more resilient crops.
Researchers from the University of Münster and Düsseldorf provide an in-depth summary of the dynamical density functional theory, a method used to describe interacting particles. The article covers various branches of physics and applications in chemistry, solid state physics, and biophysics.
New research by the U.S. Army reduces unpredictability of current training reinforcement learning policies, enabling robots to reason and adapt to changing battlefield conditions. The breakthrough enhances the Army's future operating concept by incorporating risk sensitivity, safety constraints, exploration, and divergence to a prior.
A recent study by University of Pennsylvania School of Medicine reveals significant disparities in telemedicine use, particularly among older adults and patients from minority populations. The study found that patients over 55 were less likely to participate in telemedicine visits, with those over 75 being 33% less likely.
A study published in JAMA Psychiatry found that COVID-19 pandemic led to decreased suicides in the overall population, but increased suicides among Black Marylanders. The researchers highlight the importance of identifying high-risk groups and vulnerable populations to reduce suicide numbers.
A new imaging technique has been developed to identify non-ferromagnetic projectiles that are safe for MRI, enabling patients with ballistic embedded fragments to receive medical treatment. The technique uses radiography and CT images to distinguish between ferromagnetic and non-ferromagnetic bullets, allowing for safer MRI scans.
Researchers have developed a simple, high-throughput method for transferring isolated mitochondria into mammalian cells, allowing for the study of mitochondrial DNA diseases and potential treatments. The new device, MitoPunch, enables the transfer of mitochondria into thousands of recipient cells simultaneously.
Researchers found that haemoglobins in diverse species, including humans, molluscs and crustaceans, originate from a single ancestral gene. This discovery suggests that the appearance of haemoglobin in these species was not an independent invention but rather a result of evolutionary inheritance.
Patients with COVID-19 often suffer from severe pneumonia despite low arterial blood oxygen levels, contradicting typical symptoms of hypoxemia. Researchers suggest that SARS-CoV-2 infection in the carotid body may alter its ability to detect oxygen levels, leading to silent hypoxemia.
Researchers at Osaka University developed twisted molecular wires that can conduct electricity with reduced resistance. The creation of smaller islands that are closer in energy maximized the conductivity, and temperature measurements confirmed the role of electron hopping.
Researchers from UOC Faculty of Health Sciences will investigate the impact of intermittent fasting on organ ageing in postmenopausal women. The study aims to validate ageing markers and determine if fasting leads to changes in organ ageing, with potential benefits for women's quality of life.
A University of Cincinnati study found that remdesivir permanently stops the activity of an enzyme needed for medication breakdown, increasing toxicity with certain heart and anticancer drugs. The researcher recommends using remdesivir with caution in patients with specific enzymes and in proper dosages.
Researchers found that red algae polysaccharides can suppress the activity of immune cells in lab mice, reducing leukocyte count and congenital immunity cell activity. However, it is unclear whether this effect is beneficial or detrimental, and further study is needed to understand its potential as a pharmacological substance.