New research from the University of Colorado Anschutz Medical Campus suggests that changes in the environment may contribute to the rising incidence of type 1 diabetes. The study examined various environmental exposures and found that none of the associations were strong enough to explain the rapid increase alone.
Researchers found that athletes who used a load velocity profile lifted less overall but gained strength and power, improving muscular performance. The study suggests that traditional training methods may not be the most effective, as athletes may lift too much or too little, leading to fatigue and injury.
Exequiel Ezcurra, a professor of ecology, has been recognized for his leadership in bringing together research, education, outreach, and policy to protect the environment. He has made significant contributions to conservation science, ecosystem management, and policy outcomes.
University of Groningen physicists have visualized hydrogen atoms at the titanium/titanium hydride interface, resolving a long-standing challenge in materials science. The new technique allows for the observation of both heavy titanium and light hydrogen atoms, shedding light on their interaction and properties.
Researchers have discovered two crucial mechanisms that contribute to the robust orientation of polarized proteins along the long axis of the fertilized egg. The study shows that the ellipsoidal geometry of the egg influences patterning and selection of the long axis polarization.
Researchers at the University of Illinois found that tasting or consuming sucralose can affect blood glucose and insulin levels, even in healthy individuals. The study suggests that sweetness should be consumed in moderation regardless of calories.
A new study by University of Cincinnati researchers shows a 2,328% increase in naloxone prescriptions dispensed in Ohio since 2015. Low-employment counties had 18% more prescriptions dispensed per month compared to high employment counties.
A new study describes the arrival of the potentially invasive bryozoan Membranipora membranacea on Antarctic coasts via macroalgae, highlighting the vulnerability of Antarctic ecosystems to non-native species. The discovery raises concerns about the potential ecological impact and dramatic changes to local marine communities.
A recent study by Dr. Mark Chapman optimizes protocols for identifying simple sequence repeats (SSRs) in genomic and transcriptomic data, increasing efficiency in microsatellite discovery. The research found that small assemblies of two million read pairs can generate sufficient markers for basic population genetic studies.
A study by the University of Texas M. D. Anderson Cancer Center shows that a lung cancer screening decision aid delivered through tobacco quitlines effectively reaches a screening-eligible population and results in informed decisions about lung cancer screening. The decision aid, which explains eligibility, risks, and benefits, encoura...
A global team of scientists is analyzing satellite and drone data to better understand the impact of climate change on Arctic vegetation. The research found that the greening of Arctic regions is caused by more than just warming temperatures, with other changes including differences in snowmelt and landscape wetness.
The study found that rates of new colorectal cancer cases increased substantially among individuals turning 50, indicating a shift in the disease's age distribution. This significant increase suggests that current screening age recommendations may need to be reevaluated.
Cancer cells use a camouflaging effect to escape the immune system by binding to SHP2 and PD1, activating a response switch-off mechanism. Researchers at the University of Freiburg and Leibniz University Hannover have identified this protein interaction as a target area for new treatments.
A recent study published in Nature Communications discovered that a specific Long noncoding RNA called LincIRS2 is essential for maintaining healthy metabolism. Mice lacking this gene developed metabolic complications, while those with activated LincIRS2 maintained normal blood sugar levels even in obesity.
The University of North Carolina at Chapel Hill has secured renewed funding for the Cancer Prevention and Control Research Network (CPCRN), a flagship program for preventing and controlling chronic diseases. Researchers from eight institutions will collaborate to produce research on implementing evidence-based approaches to reduce canc...
A genetic mutation in SRSF2 disrupts DNA's message sending process, leading to excessive NMD activity that destroys healthy blood cells. This excessive activity is a hallmark of blood cancer. Researchers discovered an effective treatment approach using antisense oligonucleotide therapy.
George Mason University Professor Linda Mason received a grant to develop and implement activities promoting inclusion in early childhood education. The project aims to build capacity of quality programs through partnerships with leaders in early childhood special education.
Intratumoral SD-101 injection complements low-dose cyclophosphamide in boosting innate immunity and driving potent T cell-mediated anti-tumor responses. This combination therapy improves efficacy against non-injected tumors and long-term survival, even in large tumors.
A recent study published in Biological Reviews found no conclusive link between wild birds and human illness involving E. coli, Salmonella, and Campylobacter. The researchers highlighted the need for more definitive research to determine the risks of bird populations on food safety before taking action.
Researchers create a novel, flame-retardant electrolyte for potassium and potassium-ion batteries, enabling safe operation at reduced concentrations. The new electrolyte allows for stable cycling of batteries with concentrations suitable for large-scale applications.
A study published in Frontiers in Veterinary Science found that a program combining horseback riding and cognitive training improved motor skills, behavior, and academic performance in children with neurodevelopmental disorders. The program showed promise for improving the lives of young people with ADHD and autism spectrum disorder.
Researchers found a significant spike in new colorectal cancer diagnoses between ages 49 and 50, indicating many latent cases were likely going undiagnosed until screening began. The majority of these cases (93%) were invasive, requiring aggressive treatment, including surgery.
The Society for Developmental and Behavior Pediatrics Clinical Practice Guideline provides a framework for diagnosing and treating complex ADHD in youths. The guideline aims to improve systematic approach to diagnosis and treatment for children with persistent ADHD symptoms.
Researchers developed a Noncontact Catalysis System (NCCS) to accelerate chemical reactions using gold nanoclusters as intermediaries, enabling independent reactions of normally incompatible substances. This breakthrough could lead to more versatile, efficient, and cost-effective industrial chemical production processes.
Researchers at Yale School of Public Health have identified a new family of surface proteins, Fam10, which are uniquely associated with infectious metacyclic parasites transmitted by the tsetse fly. Vaccination with one member of this family significantly reduced parasitemia in mice, making Fam10 proteins promising vaccine candidates.
Researchers found that Dirac semimetals exhibit robust, conducting electronic states in 1D, challenging previous conclusions about the nature of these materials. The discovery settles the decades-old problem of whether condensed matter Dirac fermions have topologically protected surface states.
Physicists propose using ultra-high energy neutrinos to study interactions beyond the standard model, with a new resonance dubbed the 'Zee burst.' This detection could reveal exotic particles such as supersymmetric partners and heavy decaying dark matter.
Researchers found CNVs to be genomic modifiers of ASD/DD risk in individuals with PHTS, providing insight into the disorder's clinical outcomes and potential predictors for medical management. The study suggests CNV burden analysis may aid in predicting clinical outcomes for other clinically heterogeneous disorders.
Researchers found similarities between the novel Wuhan coronavirus's receptors and those of SARS-CoV, a key finding in understanding its ability to infect humans. The study suggests that mutations in the virus could enhance its binding to human ACE2, leading to increased transmission.
Researchers from Yale School of Forestry & Environmental Studies argue that the IPCC guidelines need improvement to accurately calculate and report greenhouse gas emissions. They suggest using satellite imagery and machine-learning tools to expedite quantitative synthesis and address data gaps.
Patients living with HIV who attend religious services regularly experience higher emotional and physical well-being, while privately religious individuals face mental health challenges. Researchers suggest integrating spiritual beliefs into holistic treatment programs to improve health outcomes.
A new Ohio law allowing pharmacists to dispense naloxone without a prescription has been linked to an increase in naloxone dispensing rates. The study found that the law resulted in more naloxone being made available to patients, potentially saving lives in opioid overdose situations.
Researchers at McGill University have launched interactive story maps to highlight the importance of wetlands, which support a disproportionately high number of endangered species. Wetlands also naturally combat climate change by storing carbon dioxide underground.
Researchers at Louisiana State University have developed a new cationic cobalt bisphosphine hydroformylation catalyst system that is highly active and extremely robust. The discovery has the potential to replace rhodium-based catalysts, which are currently expensive and in short supply.
A comprehensive study of congenital heart disease found lower predicted long-term survival, higher remission rates, and lower prevalence in low-income countries compared to high-income nations. The study revealed a significant disparity in CHD mortality rates between countries, with most deaths occurring in infants under one year old.
A new study published in Nature Communications found that sevoflurane anesthesia leads to more metastatic burden in the lung after breast tumor resecting surgery than propofol. The findings may guide clinicians in optimizing anesthesia choice for breast cancer surgery to achieve best long-term outcomes.
Dr Johann Rafelski reviews decades of work on quark-gluon plasma, exploring strangeness production and discovery methods. He highlights the evolution of understanding this primordial material, which once filled the Universe, and the ongoing experimental efforts to recreate it.
Researchers found that smelling roses before and after bedtime can improve English vocabulary learning by 30%. The study suggests a practical application of fragrances to enhance learning during sleep.
A Far Eastern Federal University scientist is working on a new photopolymer silicone that can be quickly cured through UV radiation, enabling complex configurations. The compound aims to overcome the challenges of current silicone printing technology, which is currently unsuitable for producing detailed parts.
Researchers from Trinity College Dublin used supercomputers to simulate quantum systems and found a deep link between entanglement and thermalisation. The study provides new insights into the fundamental process of thermalisation and its relationship with quantum mechanics.
Researchers developed a novel anti-CEACAM antibody for fluorescence visualization of colorectal tumors and metastases. The antibody targets multiple CEACAMs, which can lead to improved detection of tumor margins and metastases with variable expression of CEA.
A special issue of Young explores how young people use music to express their feelings on the crisis, with studies focusing on feminist reggaeton in Spain and rap/mahragan in Egypt. The research shows how these genres have become politicized tools for subversive empowerment and resilience.
A study suggests that combining NKTR-214 with adoptive cell therapy may produce a stronger immune response against advanced melanoma, increasing the number of anti-tumor immune cells and their lifespan. This approach could be effective for more patients with advanced solid tumors.
Researchers developed a new database of gene essentiality, providing insight into the causes of rare childhood diseases. The study identifies new mutations likely responsible for these conditions and offers a valuable resource for clinicians and researchers.
According to a new study, human activities have inadvertently increased plant growth globally, which absorbs carbon dioxide and cools the planet. This 'global greening' trend could be slowing down global warming by up to 0.2-0.25 degrees Celsius.
Researchers at Monash University developed a wearable device using continuous wave radar and photoplethysmogram sensors to calculate continuous blood pressure measurements. The device achieved high accuracy rates, with 93% success during sedentary tasks and 83% during exercises.
The technique reduces waiting time for compatibility testing, improving transplant surgery scheduling and alleviating patient stress. Virtual crossmatching resulted in a 2.4-hour decrease in cold ischemia time and a 26% decline in delayed graft function.
Pre-clinical studies reveal that cortical spreading depression and calcitonin gene-related peptide (CGRP) play significant roles in migraine. Botox, CGRP, and PACAP-38 show promise as potential treatments.
Researchers have discovered that the glymphatic system goes awry during a stroke, promoting brain cell drowning and swelling. This finding may lead to novel interventions to reduce stroke severity and improve outcomes.
The study reveals an intricate universe of nanoscale rods, sheets and spirals that form spontaneously in eutectic solidification. This discovery could lead to the creation of lightweight alloys and optical products with superior properties.
A new modelling study estimates that up to 75,800 individuals in Wuhan may have been infected with 2019-nCoV by January 25, 2020. The researchers also suggest that multiple major Chinese cities might have already imported dozens of cases of 2019-nCoV infection from Wuhan.
Researchers at George Mason University will investigate the role of early life exposures in childhood health and disease as part of a $1.5M NIH grant. The project aims to understand how early life experiences impact children's development and health outcomes.
The University of Texas Health Science Center at Houston has received a $3 million grant to provide child development strategies to infant and toddler specialists and teachers. The training focuses on improving interactions between teachers and children, as well as family engagement strategies to build strong emotional and social skill...
A new cryopreservation technique has been developed to preserve genetically modified rat spermatozoa, which are difficult to store due to their large size and sensitivity to temperature changes. The method, tested on genetically modified rats, successfully produced over 300 offspring from a single male rat.
Researchers analyzed DNA data from African American and Caucasian American men with prostate cancer, finding lower frequencies of pathogenic/likely alterations in 14 well-characterized DNA repair genes among African Americans. The study suggests a higher risk for germline BRCA mutations but lower risks for non-BRCA mutations
Researchers at Boston University School of Medicine have identified the unique genetic program behind primordial lung progenitors, a rare and transient cell type. This discovery may lead to improved stem cell protocols for treating respiratory diseases such as COPD, cystic fibrosis, and lung interstitial disease.
A recent study using national data from over 895,000 US adults examined the association between state regulations and e-cigarette use. The results show that stricter state regulations are linked to lower adult e-cigarette use.
A four-year project examined how schools use screening tools and factors influencing their use. The study found that school leader knowledge and attitudes are key to proactive screening approaches, leading to better outcomes for students.
Researchers identified novel PMEPA1-e isoform and characterized its biological functions in prostate cancer. The study found that the methylation of PMEPA1 gene promoter accounts for silencing of PMEPA1 in prostate cancer cells.
Disturbances in the internal clocks of pancreatic cells are linked to type-2 diabetes. Researchers successfully restored clock function using a natural compound, improving insulin secretion and providing new hope for diabetes care. The study shows that synchronizing the internal clocks can help regulate blood sugar levels.