Researchers identified specific genomic regions that have changed in response to natural selection to allow plant species to adapt to new climatic conditions. These adaptations are linked to traits such as winter survival and flowering, enabling plants to thrive in diverse climates.
Researchers at Karolinska Institutet discovered that MAIT cells respond with dynamic activity and reprogramming of gene expression during acute HIV infection. The study sheds light on the immune system's response to this phase of HIV infection.
Researchers found that prehospital epinephrine administration was associated with improved return of circulation in pediatric patients with out-of-hospital cardiac arrest. However, there was no significant improvement in 1-month survival rates. The study suggests that prehospital epinephrine administration should be included in interna...
Researchers have found that MYC and TWIST1, two genes that promote cancer development, work together to recruit immune cells to tumors, creating an environment that facilitates cancer cell spread. Blocking a key step in this process may help prevent metastasis.
Research on red titi monkeys reveals that female pair bond maintenance is driven by relationship management, while males provide useful services like offspring care and territory defense. The study supports the 'male-services hypothesis' suggesting females prioritize proximity to maintain relationships.
The Healthy Hunger-Free Kids Act led to significant improvements in school meal quality, with increased whole grains, dairy, and fruits, while reducing refined grains. Participation rates rose in schools serving healthiest lunches, offsetting concerns about costs.
Researchers have developed DNA-binding editorial assistants to open up genes obscured by chromatin packaging, enabling CRISPR editing. This breakthrough enhances CRISPR efficiency and moves towards genetic-based assaults on diseases.
Researchers analyze Cassini data to study Saturn's ultraviolet auroras and their dynamic processes. The new observations provide unique views of the small-scale structures behind these auroras, revealing similarities with Jupiter's magnetosphere.
A study by University of Michigan researchers sheds light on the role of WDR5 and p53 proteins in influencing stem cell fate, with implications for cancer research and potential treatments for heart disease. The team found that inducing a short delay in WDR5 expression steered embryonic stem cells towards different tissue types.
The resale ticket market appeals to season ticket holders who want to recoup costs, reducing the need for fans to buy full-season passes. This boosts team revenues by creating an alternative supply of tickets.
Researchers at Ohio State University Wexner Medical Center suggest a new approach to treating advanced, progressing bile duct cancer. The study found that adding an mTOR inhibitor may re-sensitize tumor cells to FGFR inhibitors in patients who develop resistance to these agents.
A newly discovered genetic element on dog chromosome 15 influences coat color intensity by affecting pigment distribution along the hair. Dogs with higher copy numbers of this region have more intense coat colors.
Children are more likely to delay gratification when working together with a peer, according to new research. The study found that children from diverse cultural backgrounds showed improved self-control in cooperative conditions, suggesting an early development of social obligations.
A recent study by the University of Gothenburg found that many 70-year-olds in Sweden overestimate their eyesight, but can still see considerably better with glasses or power correction. The study also highlights the importance of regular eye exams to detect visual impairment and age-related diseases.
Dr. Margaret A. Goodell, a renowned hematopoietic stem cell researcher, has been awarded the Tobias Lecture Award by the International Society for Stem Cell Research (ISSCR). Her pioneering work on epigenetic regulators of normal hematopoietic stem cell function has greatly advanced our understanding of hematologic malignancies.
Researchers at the University of Minnesota are developing a new device to administer a recently developed antidote for cyanide poisoning, which could save lives in mass-casualty settings. The autoinjector, designed by Windgap Medical, would deliver a single dose of sulfanegen, an antidote that takes effect within minutes.
A new study by New York University researchers reveals that flame retardants and pesticides are now the leading causes of IQ loss in children, outweighing heavy metals. The study found that over 1 million children suffered from intellectual disability between 2001 and 2016 due to exposure to these toxic chemicals.
Researchers at University of California San Diego School found that alcohol dependence remodels the functional architecture of mouse brains, leading to increased coordinated activity and reduced modularity. This change is associated with cognitive impairment, emotional distress, and intense craving in mice.
Researchers found that intentionally adding defects to lithium-ion batteries can cause stress, leading to cracks and degradation. The study suggests a sweet spot for defect levels to optimize performance, contradicting previous findings.
Researchers have found that certain microbes affect sperm quality, fertilization, embryo implantation, and reproductive health across various animal species. The study also sheds light on the role of the reproductive microbiome in sexual selection, mating systems, and sexual conflict.
Researchers have identified nine galactic sources of super-high-energy gamma rays with energies over 56 trillion electron volts, three of which emit gamma rays extending to 100 TeV and beyond. These discoveries help explain where high-energy particles originate and how they are accelerated.
A team of researchers from MIT has developed an algorithm to solve hard combinatorial problems using optical machines. This breakthrough has the potential to revolutionize fields such as biology, drug discovery, and routing/scheduling by leveraging the advantages of optical hardware integrated into silicon photonics.
InDepth Pharmaceuticals has executed an option agreement to evaluate a novel diagnostic technique that can predict kidney transplant success in patients with focal segmental glomerulosclerosis (FSGS). The company aims to serve all 1 million FSGS patients worldwide and develop new therapeutics for other forms of kidney disease.
Princeton researchers recreated a crucial cell division process outside a cell, uncovering the vital role of protein TPX2 in over 25% of all cancers. The team's findings reveal TPX2 facilitates efficient microtubule assembly and spindle formation by acting as a liquid-like molecule.
The study examines changes in FDA approval processes and regulation of pharmaceuticals from 1983 to 2018, finding increased approvals of generic drugs and biologics. The number of expedited development programs expanded while the amount of evidence required for approvals decreased.
A study published in BJS Open found that mortality rates from colorectal cancer surgery are significantly higher in smaller hospitals with lower annual case numbers. Hospitals performing more operations per year have better patient survival rates, likely due to increased access to specialized care and equipment.
The study found that the depth of porphyry copper and gold deposits influences their composition, with deeper deposits containing more copper and shallower deposits containing more gold. Over 95% of gold is lost to the atmosphere through volcanic emissions, making it challenging for companies to extract this metal.
A new study assesses the impact of deep-sea mining on microbial ecosystems, highlighting the need for policy makers and industry to understand microbes' roles and services they provide. Microbial processes and animal communities are slow to recover from disturbance, and damage can lead to irreversible loss of ecosystem processes.
Researchers have developed a new small molecule that potentiates synaptic NMDA receptors, restoring brain rhythms to normal patterns and improving memory in mouse models of Alzheimer's disease and Dravet syndrome. The treatment also reduced abnormal brain activity associated with these conditions.
A collaborative campaign is launching in El Paso to ensure historically undercounted populations are included in the 2020 census. Community health workers and local organizations will drive outreach efforts to educate and communicate the importance of census participation.
Researchers developed a new method to pre-replenish lithium for lithium-ion supercapacitors using DMF-stabilized lithium nitride. This technology improves specific energy, rate performance, and cycle stability, with 90% energy retention after 10,000 cycles.
Researchers have discovered that organic LEDs (OLEDs) exhibit regions of reduced brightness known as 'switched-back' effects, despite increased applied current. This phenomenon is attributed to negative differential resistance induced by nonlinear electrothermal feedback, which can lead to unstable operation and device breakdown.
A recent study by Finnish Institute for Health and Welfare found that indoor air quality is connected to respiratory and general symptoms like colds and headaches. However, the association was too weak to reliably assess indoor air quality based on reported symptoms.
Scientists have successfully generated and manipulated spin currents in graphene, a unique material for long-distance spin transport. This breakthrough has the potential to revolutionize the development of efficient and versatile spin-based technologies.
A rapid diagnosis centre has reduced waiting times for patients with non-specific symptoms who may have cancer to under 6 days. The study also found that if the RDC runs at full capacity, Swansea Bay University Health Board could save £157,858 and gain 9.2 quality-adjusted life years.
A team of scientists has discovered a voltage-induced 'superfluid' like penetration effect in liquid metals at room temperature, mimicking the properties of liquid helium superfluids. The phenomenon occurs due to the reduction of surface tension, enabling the liquid metal to superwet and penetrate porous materials.
Scientists discovered more evidence of archaic introgression in immunity-related genes and found a possible resistance to malaria among Papua New Guineans. They also identified genes related to porphyrins, energy metabolism, and olfactory receptors showing signals of Neandertal introgression.
A new Stanford study finds that analyzing DNA in soil can identify nearly every animal present in an area, including rare species, with high accuracy. The technique also distinguishes between similar-looking animals and has potential to reveal previously unknown species diversity.
Researchers at OHSU assess barriers to care in 10 preventive services, finding enhanced services like patient navigation increase cancer screening rates. Additional research is needed to better understand patient and provider barriers and the role of health information technology.
A large-scale study of over 100,000 people revealed new genetic targets for a variety of diseases, including autoimmune disorders and cancer. The research also identified potential repurposing of existing drugs to target these conditions.
Researchers at UC Davis have identified novel inhibitors that can disrupt redox signaling to prevent haustorium initiation in parasitic plants. This breakthrough could lead to new control methods against economically damaging agricultural pests.
Researchers at Stockholm University discovered engineered silica particles can reduce food efficiency, leading to lower weight gain and improved metabolic profiles in mice. The study suggests these particles could be used to treat obesity and diabetes in humans.
Dr. Allon M. Klein receives the Dr. Susan Lim Award for his groundbreaking contributions to stem cell and developmental biology, including novel approaches to adult stem cell self-renewal and a cell-isolation system for transcriptional analysis.
Researchers at Massachusetts General Hospital develop new non-surgical Coolsculpting method targeting fat almost anywhere in the body using a safe, injectable ice solution. The technology selectively reduces fat tissue at any depth and site accessed by a needle or catheter.
Researchers have identified a probiotic that slows and reverses the build-up of alpha-synuclein protein, which is associated with Parkinson's disease. The probiotic, Bacillus subtilis, produces chemicals that change how enzymes process specific fats, preventing toxic clumps from forming.
A new study published in Family Practice shows a significant gender gap in biomedical paper publication rates, with women accounting for 48% of first authors in primary health care journals. The study found that women are less likely to publish articles on trials and have fewer research grants, contributing to the disparity.
A new study reveals a worrying trend of urban sprawl worldwide, with less connected street networks in many cities. Cities like Tokyo and Buenos Aires offer inspiration for limiting sprawl, while gridded street networks promote efficient and dense urban form.
A study of over 650 women who experienced early-stage pregnancy loss found that nearly a third suffer post-traumatic stress, while one in four experience moderate to severe anxiety and depression. The research calls for improved care following an early-stage pregnancy loss.
Researchers identified five main European sign language lineages that dispersed globally from the late 18th century, tracing their evolution through a comprehensive database of manual alphabets and handshapes. The study provides new insights into the origins and spread of sign languages, highlighting unexpected connections between Aust...
Researchers developed a novel cryogel vaccine that primes the immune system to attack and eliminate acute myeloid leukemia cells in mice. The vaccine successfully protected against disease recurrence when combined with chemotherapy.
Researchers at the University of Ottawa offer a unique tool to accelerate nanopore research development, making it more accessible and affordable. The innovative approach enables fast, low-cost, and automated fabrication of solid-state nanopores, which hold promise for various applications in medicine, IT, and life sciences.
Infected mice exhibit decreased general anxiety and increased exploratory behavior, as well as reduced aversion to various threats. The parasite achieves this through neuronal inflammation rather than direct interference with specific neuronal populations.
Researchers from Yokohama National University have developed a new method using slow light to create a compact and non-mechanical LiDAR sensor. This technology has the potential to improve the performance of LiDAR sensors in various fields, including autonomous vehicles, robots, and drones.
Researchers at Worcester Polytechnic Institute have developed a new tool to identify molecular receptors in Caenorhabditis elegans worms involved in sensing pheromones. This breakthrough could speed up neuroscience research into pheromones by streamlining the process and identifying specific receptors in just a month.
Researchers found an elevated overall cancer incidence among World Trade Center responders, especially in thyroid and prostate cancers. Leukemia is also reported for the first time, likely due to low-level benzene fuel exposure.
A new AI-powered method predicts building energy consumption by analyzing environmental and operational parameters, offering a significant improvement in energy management. The hybrid deep learning model has the potential to be applied in various smart buildings and cities.
Researchers discover 15 new species of parasitoid wasps that manipulate spider behavior to protect their young. The wasps' complex web-spinning abilities are a rare phenomenon in nature.
Dr. Mitinori Saitou has made groundbreaking contributions to understanding mammalian germ cell development and reproduction in vitro. His work has enabled the generation of functional gametes from pluripotent stem cells and improved germ-cell technology.
Researchers used Life Cycle Assessment to identify environmental hotspots in the production of lactic acid, a key bioplastic. The study found that heavy solvent usage and black energy consumption can negatively impact sustainability. Additionally, the development phase is crucial for identifying and addressing these hotspots.
A study found that antibiotics are widely available without a prescription in Chinese retail pharmacies, hindering the government's goal to make them prescription-only by 2020. The survey revealed that 83.6% of pharmacies sold antibiotics without a prescription, with no significant differences between urban and rural locations.