A new study suggests that rare, harmful genetic mutations present in healthy donors' stem cells can be passed on to cancer patients, causing heart damage, graft-versus-host disease and new leukemias. The study analyzed DNA samples from 25 AML patients and their matching donors, revealing 44% of donors had at least one harmful mutation.
Sallie Permar, a pediatric researcher focused on neonatal viral infections, has been recognized with the SPR Award in honor of E. Mead Johnson. Her research has led to significant breakthroughs in understanding neonatal viral infections, including the development of vaccines for prevention of vertical virus transmission.
A new study from the Smidt Heart Institute found that women's blood vessels age faster and are more susceptible to high blood pressure earlier in life. The research highlights sex differences in cardiovascular physiology and disease, emphasizing the need for tailored treatment approaches.
A study of over 23,000 adult childhood cancer survivors found a significant decline in serious heart conditions and coronary artery disease risk since the 1970s. The decline is largely attributed to efforts to reduce toxic effects of treatment, including radiotherapy.
EMBO has awarded nine researchers with Installation Grants to set up independent laboratories in the Czech Republic, Poland, Portugal, and Turkey. The grants support young group leaders in establishing their labs in countries that struggle to compete scientifically with well-funded research centers.
Researchers studied male chimpanzees' social relationships, finding strong bonds with maternal brothers and old males, including biological fathers. This challenges the idea that pair bonds evolved first in humans, suggesting elements of fatherhood may have arisen earlier in a similar social system.
A single payer system would replace private insurance and simplify billing, leading to savings through lower drug costs and efficiencies. The study found that 19 of 22 models predicted net savings in the first year, averaging 3.5% of total healthcare spending.
Antimalarial drugs are found to work against each other when combined, a phenomenon known as antagonistic cooperation. This discovery could lead to more effective treatments for malaria, a disease that killed 435,000 people in 2017.
An international team of researchers has developed an online system to create accessible math textbooks in Braille, overcoming challenges such as representing maths formulas and graphs. The project aims to provide equal access to knowledge for blind students, enabling them to touch and compare mathematical concepts.
A study by Ohio State University researchers found that a pig virus is easily transmitted to healthy chickens and turkeys, developing diarrhea in as little as two days. The virus's rapid spread has raised concerns about its potential impact on humans, who are susceptible but may not show symptoms.
A new study suggests that targeting astrocyte calcium signaling could decrease amphetamine behavioral effects and potentially develop therapies for diseases with dysregulated dopamine. Astrocytes were previously considered 'support cells', but now shown to actively contribute to brain function.
Researchers at Northwestern University have developed a new semiconductor neutron detector that can absorb thermal neutrons and generate electrical signals. The material is highly efficient, stable, and can be used in small, portable devices for field inspections or large detectors for national security applications.
According to NASA and NOAA analyses, Earth's global surface temperatures in 2019 were the second warmest since modern recordkeeping began in 1880. The past five years have been the warmest of the last 140 years. Rising temperatures are contributing to mass loss from Greenland and Antarctica and increases in extreme events.
Researchers analyzed how juvenile male zebra finches learn to sing using a novel framework that revealed multilayered changes in brain wiring. Good songs improve slowly over time, while bad ones change quickly but are often forgotten the next day.
New research suggests lactate is a catalyst that triggers cancer forming process in mutated cells. The study's findings open a new door to better understand cancer at the metabolic level and could lead to targeted therapies.
A recent study highlights the unreliable sources of probiotic information online and how health-benefit claims are often not supported by robust scientific evidence. Most websites providing probiotic info are from commercial sources or news outlets, which provide incomplete information on potential side effects and regulatory issues.
Researchers analyze cyclical changes in light spectrum emitted by Proxima Centauri and suggest the presence of a second planet. The candidate planet orbits every 5.2 years and may be a 'super-Earth', challenging current models of low-mass planet formation.
The Pachacamac Idol, a sacred icon worshipped for nearly 700 years, was symbolically painted with red, yellow, and white colors using cinnabar pigment. The study confirms the idol's polychromatic design and sheds light on pre-Columbian cultural practices in South America.
A pilot study of 25 donor-recipient pairs reveals young stem cell donors have previously undetected and potentially disease-causing mutations in their blood stem cells. These mutations, linked to post-transplant complications, are more prevalent in young donors than thought.
Researchers created a green living material that demonstrates similar strength to cement-based mortar by combining sand, bacteria, and hydrogel. The material reproduces and can be controlled to maintain structural function and microbial survivability.
Researchers have created a new type of semiconductor neutron detector that boosts detection rates by reducing the number of steps involved in neutron capture and transduction. The LiInP2Se6 material converts neutrons into pairs of charged electrons and holes, generating a current directly detectable thermal neutrons.
A study of 537 Russian primary school students found that the emotional component of school engagement is the most important factor in motivating children to learn. The researchers adapted an international questionnaire and analyzed data, confirming the validity and reliability of the survey.
A severe and long-lasting marine heat wave, known as 'the blob,' led to the largest seabird die-off in recorded history. The common murre population declined drastically due to a shortage of forage fish and increased competition from large predators.
A systematic review of 422 studies found evidence of adverse effects of ageism on mental and physical health conditions, including depression and shorter life expectancy. Ageism also affects access to healthcare treatment, with denied care found in 85% of relevant studies.
Researchers at KU Leuven developed a new antibacterial strategy that prevents bacterial cooperation, reducing the emergence of resistance. Non-resistant bacteria outnumber resistant ones, making it harder for them to spread.
Researchers successfully demonstrated a quantum dot LED that operates as an optically pumped laser, clearing the path towards versatile colloidal quantum dot laser diodes. These devices have the potential to revolutionize fields like photonics, optoelectronics, and medical diagnostics.
Researchers propose a sampling regime inspired by geostatistics that includes regular and random intermediate points to capture fine-scale behaviors. This approach provides more accurate estimates of movement parameters than traditional regular sampling regimes.
When non-motile E. coli and motile A. baylyi are mixed, stunning floral patterns emerge due to differences in growth rate, motility, and friction against the agar surface. This phenomenon has important implications for understanding growing biofilms.
Researchers at University of Bath identified a molecule called DIRC3 that acts as a tumour suppressor to block melanoma cell growth and spread. High levels of DIRC3 expression in patients were linked to increased survival rates, suggesting its potential as a new treatment for skin cancer.
The Duodenum Intestine-Chip, a living product from Emulate, Inc., was shown to accurately recreate key functions of the human duodenum. The chip demonstrated superior functionality compared to organoids alone in terms of global transcriptomic profile and physiological function.
A study of 1225 adolescents found that conversational difficulties with fathers after divorce are strongly connected to increased health complaints. The researchers also observed that closeness to both parents impacts children's health two years after the divorce.
Researchers at HRL Laboratories found that targeted transcranial electrical stimulation during slow-wave sleep can improve metamemories of specific episodes by nearly 20% after just one viewing. This non-invasive approach may benefit patients with learning and memory deficits, as well as those with PTSD.
Researchers found that cannabinoids can relieve pain caused by endometriosis and improve cognitive function in mice with the condition. THC treatment also reduced endometrial growths, suggesting a potential therapeutic effect.
Women who have sex weekly are 28% less likely to experience early menopause, according to a new study published in Royal Society Open Science. The research found that having less sex is associated with an earlier menopause, suggesting a biological trade-off between investing energy in ovulation and other activities.
Researchers detect lower levels of a protein found in brain connections in people with schizophrenia, which could underlie cognitive difficulties and provide targets for new treatments. The study's findings suggest that loss of synapses may be linked to the development of schizophrenia.
A study found that an overactive immune system gene causes schizophrenia-like changes in mice, including neural and behavioral aspects of the disease. The researchers suggest that this gene may be contributing to the development of schizophrenia through mis-regulated synaptic pruning.
Dr. Fred H. Gage has made groundbreaking discoveries in stem cell biology, neuroscience, and human evolution. His work has broad implications for treating diseases like Alzheimer's, Parkinson's, and mental health disorders.
Researchers used microeconomic models to analyze the circumstances required for reciprocal egg trading to work. The results reveal that eggs must be costly to produce and it's essential to identify cheaters before mating. This complex system of trading helps hamlets avoid a costly dilemma by dividing the reproductive role.
Research reveals sand mining on the Mekong River is causing significant erosion, with riverbanks collapsing when lowered by just two meters. Excessive sand mining poses environmental and social risks, emphasizing the need for stronger regulations to protect communities.
Researchers at Ohio State University Comprehensive Cancer Center discover a direct connection between thrombin and TGF-b1, a cytokine promoting tumor progression and suppressing immune responses. Blocking this mechanism prevents tumor resistance to immunotherapy and increases tumor-infiltrating immune cells.
A randomized clinical trial found that a telephone-based program encouraging increased vegetable consumption did not decrease the risk of prostate cancer progression over two years. The study suggested that the intervention may have been underpowered to identify a clinically important difference in cancer progression.
James Gilchrist's project uses microrheology to study paint drying processes and develop a testing method to predict performance. The goal is to improve paint formulations, reduce energy consumption and costs in the automotive industry.
A Rutgers-led team has found that altering a protein called Connexin-43 may alleviate DMD-related heart disease by protecting against irregular heartbeats and late-stage failure. This discovery offers hope for prolonging the lives of muscular dystrophy patients, who are currently plagued by heart muscle breakdown.
A Phase III clinical trial found that eating seven or more servings of vegetables and fruits daily did not provide extra protection against prostate cancer. Despite this, a healthy diet rich in fruits and vegetables may help patients tolerate cancer treatments.
The new optical nitrate sensor enables real-time measurement of nitrate levels in the range of tens to hundreds of parts per million, detecting rapidly changing concentrations. It optimizes fertilizer application, reduces water resources pollution, and economizes irrigation.
A study by Portland State University researchers found that diverse crowds of local stakeholders can collectively produce complex environmental models similar to those of trained experts. The results correspond more or less exactly to scientific knowledge on the subject, with the final outcomes improving as more individuals are involve...
Researchers have found that an exosome treatment can promote full recovery in swine with severe stroke, even in cases where brain cells are at risk of dying. The treatment works by interrupting the process of cell death and reducing damage signals throughout the brain network.
A new study published in Sex Roles investigates public attitudes towards the participation of transgender people in sports. The research finds that women sports fans are more likely to oppose transgender athletes participating in sports by gender identity, holding views similar to male sports fans. However, the study also reveals that ...
A new study explores how ranchers make decisions about managing their land, finding that cultural considerations and the desire to maintain traditional practices are key drivers. The research highlights the importance of considering the complex social-ecological factors at play in private lands conservation.
A study published in Environmental Research Letters suggests that global warming could lead to a significant rise in violent crime rates in the United States. The research team used climate data and an FBI crime database to identify regional connections between warming and crime rates, particularly in winter.
Tropical Storm Claudia weakened due to wind shear and dry air, with maximum sustained winds dropping to 47 mph. The storm continued to appear elongated from NASA-NOAA's Suomi NPP satellite imagery.
Researchers predict a new type of multiferroic material that combines ferromagnetism and electric polarization, potentially leading to efficient magnetic reading and writing. The study suggests that diverse magnetoelectric couplings can be achieved in thin layers, making it a promising direction for practical applications.
A study by Oregon State University researchers found a connection between children's gut microbiomes and their behavior, with those experiencing behavioral problems having different microbiome profiles. The quality of the parent-child relationship and parental stress also played a role in shaping these differences. Further research is ...
Researchers developed a method combining empirical knowledge of fishery stakeholders with scientific understanding to identify ecological cause-effect relationships in pike populations. The collective intelligence of nature users accurately captured complex human-environment relationships, exceeding scientific knowledge in some cases.
New study reveals that simultaneous X-ray and gravitational wave observations of supermassive black hole collisions will provide unprecedented insights into cosmic events. The European Space Agency's Athena and LISA missions, set to launch in the 2030s, will enable astronomers to study these phenomena in detail.
Researchers found that chronic, heavy recreational marijuana use affects driving ability even when users are not intoxicated. Earlier onset of marijuana use was associated with poorer driving performance and increased impulsivity.
A 'cold Neptune' and two temperate super-Earths, GJ180d and GJ229Ac, have been discovered orbiting nearby red dwarf stars, offering a chance to study potentially habitable worlds. The planets were found using the radial velocity method and offer insights into exoplanet formation and evolution.
A recent study published in eLife found that chronic inflammation can turn the skin's protective IgE antibody into a tumor promoter. In mice with cancer-causing mutations, chronic activation of IgE by inflammation supported the growth of precancerous skin cells into tumors.
Researchers at University College London discovered a new mechanism that allows the brain to monitor its own blood supply, potentially leading to new treatments for hypertension and dementia. Astrocytes, specialized brain cells, act as blood flow sensors to regulate brain blood flow and maintain oxygen supply.
NASA scientists used data from Suomi NPP to track Australian bushfire smoke globally, revealing its circumnavigation of the Earth. The satellite's Aerosol Index layer helps identify and track aerosols produced by wildfires, dust storms, and other events.