A multi-site randomized experiment is being conducted to test a structured investigation protocol for robbery cases in Rochester, NY, and Seattle, WA police departments. The goal is to improve clearance rates and enhance victim satisfaction through standardized investigative actions by trained patrol officers.
A study by IMT School for Advanced Studies Lucca found that a specific region of the right temporo-parietal junction can represent various affective states. The researchers used fMRI data and found smooth transitions in this region, which allows the brain to map emotions in a single patch of cortex.
A protein complex of Teneurin, Latrophilin, and FLRT attracts neighboring neurons during development, enabling synapse formation and information exchange. In early brain development, however, the same proteins repel migrating nerve cells, guiding them to their target brain area.
Research suggests that lung bacteria can predict clinical outcomes in critically ill patients, with certain bacteria associated with worse outcomes and the presence of gut-associated bacteria found in the lungs. The study's findings have implications for developing new therapies to prevent and treat critical illness.
A team of researchers developed a promising tool to combat malaria and other mosquito-borne diseases. Their genetically engineered fungus toxin killed 75% of insecticide-resistant mosquitoes, causing an established population to collapse within 45 days.
A team of researchers has developed an artificial intelligence method to predict iron deficiency responses in plants, identifying key regulatory elements and transcription factors. This breakthrough can lead to improved plant cultivation by increasing iron uptake in new varieties, enhancing adaptation to poor soil conditions.
Scientists detected Marburg virus in Egyptian rousette fruit bats in Sierra Leone, highlighting the risk of human exposure. The presence of Marburg virus means people living nearby could be at risk for becoming infected without reported cases of illness.
Michigan Tech engineers focus on lithium's unique mechanics at small scales to address battery defects. They find that at tiny lengths, lithium is much stronger than at macroscopic scales, relying on diffusion instead of dislocation motion to relieve stress.
Researchers have created a computer algorithm called CytoTRACE that can identify the most dangerous cancer cells by analyzing gene expression. The tool may help target cancer-causing genes and improve treatment outcomes for patients with aggressive forms of breast cancer.
A 30-year study details clinical course of 184 individuals with genetically diverse forms of MSUD, showing increased survival and hospitalization rates. Despite advances in care, patients continue to suffer from cognitive and psychiatric disabilities, highlighting the need for safer and more effective disease-modifying interventions.
Researchers created a blue light-emitting diode from halide perovskites, but discovered the materials are inherently unstable due to their weaker ionic bonds. The crystal structure changes with temperature, humidity, and chemical environment, affecting optical and electronic properties.
A longitudinal study of 161 children with spina bifida found that fetal surgery improved mobility and reduced the need for follow-up surgeries. Fetal surgery also resulted in fewer shunt placements and better motor skills scores compared to traditional postnatal repair.
A new technique reveals that myelin produces multiple waves of electrical potentials traveling at high speeds, contradicting earlier assumptions. This discovery has significant implications for understanding demyelinating diseases like multiple sclerosis.
Researchers at the University of Turku studied how horror movies affect brain activity and found that unseen threats are the scariest. The study revealed that brains continuously anticipate and prepare for action in response to threat, making horror movies an effective way to enhance excitement.
Researchers conducted a global census of diverse proteins on the outer membrane of cells, governing their interactions and assembly into organs. The study's agnostic approach revealed 20 new cell surface proteins important for brain wiring in fruit flies.
A new species of Allosaurus, Allosaurus jimmadseni, has been discovered in Utah, inhabiting the flood plains of western North America during the Late Jurassic Period. The species possesses unique features, including a short narrow skull and relatively long legs and tail.
A review paper in Science highlights the challenge of assessing chemical risks to wildlife, citing the need for computer modelling and long-term ecological monitoring. The authors recommend a more consistent retrospective risk assessment approach to better understand the impacts of chemicals on wildlife populations.
A University of Georgia study evaluated environmental monitoring practices across the frozen food industry to identify effective methods for controlling Listeria monocytogenes. The research found that facilities were predominantly testing for Listeria spp., but there is a need for facilities to review their sampling strategy.
Researchers have discovered a rare African-specific variant of the TP53 gene that causes iron accumulation in macrophages, leading to poorer responses to bacterial infections. However, this variant also improves response to malaria toxin, potentially offering protection against severe inflammation and disease severity.
Researchers develop a new approach for studying transitional flows, finding that the energy spectrum of small eddies conforms to Kolmogorov's universal theory. This breakthrough has practical applications in engineering, particularly in predicting friction between flow and pipe.
A new study by MIT professor Arnold Barnett reveals that airline passenger fatalities have declined significantly between 2008 and 2017, with a global fatality rate of one death per 7.9 million passenger boardings.
Researchers found that jumping genes, also known as transposable elements, play a crucial role in stabilizing the 3D folding patterns of DNA molecules. This discovery contradicts the long-held assumption that the precise order of letters in the DNA sequence dictates the broader structure of the DNA molecule.
Researchers discovered that most soil protists consume smaller organisms, while others thrive in tropical soils and are affected by annual precipitation. The study provides new insights into the ecological roles of these single-celled organisms in ecosystems worldwide.
Biology student Jenny Yi-Ti Sung studies how Beijing operas convey details about motivation and character through colorful masks. Her research reveals recurring archetypes and facial features, similar to those found in jumping spiders, which use pattern and color to communicate species, sex, and romantic intentions.
A recent study found that fewer than one-third of caregivers to older adults report being regularly asked by health care workers about needed support. Most caregivers reported positive interactions with health care workers, but the lack of regular check-ins highlights a need for improved caregiver support.
Consuming natural yoghurt daily may lower breast cancer risk by displacing harmful bacteria with beneficial ones. Breastfeeding also reduces the risk, likely due to lactose fermenting bacteria occupying breast ducts.
Toxoplasma gondii injects proteins into host macrophages, altering their behavior and suppressing the immune response. This manipulation leads to the creation of M2 macrophages, which reduce inflammation and allow the parasite to evade elimination by T cells.
A team from Wits and HUST shows that multiple quantum patterns of twisted light can be transmitted across a conventional fibre link, enabling a new approach to realising a future quantum network. The researchers demonstrated transfer of multi-dimensional entanglement states over 250m of single-mode fibre.
People with acquired facial paralysis experience higher rates of depression and anxiety due to stigma and loss of identity. Research suggests that greater protections against discrimination are needed to alleviate psychological distress.
Mirkin is being honored for multiple contributions to the fields of chemistry and nanoscience, including the discovery and development of spherical nucleic acids (SNAs) with unique chemical and physical properties. He has also invented and developed scanning probe-based tools and techniques that allow researchers to pattern nanostructu...
Researchers found that West Nile virus (WNV) inhibits autophagy to induce protein aggregation, leading to cell death and brain inflammation. A drug inducing autophagy can prevent cell death and reduce inflammation.
Researchers at Wake Forest University are testing whether weighted vests can preserve bone density and quality in older adults with obesity. The study aims to provide a low-cost alternative to traditional resistance training, which has been shown to reduce muscle loss and improve bone strength.
Brain region-specific organoids reveal transcriptional signatures of neuropsychiatric disorders and allow researchers to study chromatin accessibility and gene expression in specific cells over critical developmental stages. The development of the human forebrain is a complex process guided by epigenetic gene regulation.
FerriIridium, a novel drug, can diagnose and treat gastric cancer by selectively activating in tumor cells. The iron-based compound reduces side effects by targeting cancer cell mitochondria, leading to their destruction.
Researchers have discovered a two-drug combo that can counter resistance to a promising new breast cancer therapy. The combination of neratinib and everolimus effectively blocks the growth of cancer cells with HER2 mutations, providing a novel treatment option for patients with these types of cancers.
The 2018 Four Corners drought in the US was exacerbated by human-induced warming, with temperatures rising 2 degrees Celsius. The region's vegetation turned brown due to increased evaporation, resulting in economic losses of over $3 billion and impacts on Native American communities.
Researchers created snake venom glands as organoids, producing biologically active venom peptides. This breakthrough could lead to more efficient and cost-effective production of antivenom, addressing a pressing medical need.
A new study by UW's Institute for Learning & Brain Sciences found that bilingual teaching led to sustained English-language comprehension and vocabulary-building in infants, regardless of socioeconomic background. Online training enabled the replication of the research-based method globally.
Researchers used radiocarbon analysis to determine the carbon age of non-photosynthetic orchids, revealing they obtain carbon from dead wood via saprotrophic fungi. This finding overturns traditional views and opens a new perspective on how these plants have become ecologically successful.
New research reveals women-only business networks in Northern Ireland fail to overcome societal issues hindering female entrepreneurship. Despite policy efforts, these networks perpetuate women's marginalization and reinforce the masculinity of entrepreneurship.
A new study by Newcastle University scientists found that both UV and non-UV light from sunlight can damage the skin's cells, with visible and infrared rays causing greater harm at deeper levels. The research aims to improve sunscreen protection strategies against all three types of light.
A new study found that intensive care units (ICUs) have better end-of-life care ratings than other hospital departments, contrary to previous beliefs. The research suggests that higher staffing ratios and more favorable symptom management in ICUs contribute to these improved outcomes.
Research shows that gut microbes influence the development of specialized immune cells in the thymus, promoting a well-functioning immune system. The study highlights a novel communication between intestinal microbes and developing thymic cells, shaping the immune repertoire in early life.
Research reveals frequent RB1 intragenic rearrangements in non-smoking patients with EGFR mutations, indicating higher resistance to EGFR inhibitors. The alteration may favor growth and tumoural versatility of resistant clones.
Overweight adults who followed the Mediterranean, Intermittent Fasting and Paleo diets experienced modest weight loss (2-4kg) and clinically significant improvements in blood pressure. The Mediterranean diet also improved blood sugar levels, while the fasting diet led to slightly more weight loss.
A recent study published in Journal of Systematics and Evolution suggests that global warming could negatively impact the processes that generate biodiversity. The research focuses on the evolutionary success of Carex, a genus with over 2000 species, which is favored by cold climates during the past 10 million years.
Researchers developed a quantum reinforcement learning framework to explain human decision-making behaviors, revealing a quantum-like neural mechanism. This breakthrough suggests that the human brain functions similarly to quantum systems, with potential implications for machine learning efficiency.
The Wannier90 program has transitioned to a community-driven model, featuring new functionalities, improvements, and features. The 3.0 release includes methods for WFs calculation, parallelization, interfaces with new codes, and user functionality.
The emergence of a new coronavirus from animals to humans poses a significant threat, prompting the need for swift action. Researchers are developing diagnostic tests, exploring broad-spectrum anti-viral drugs, and adapting approaches used with earlier outbreaks to jumpstart candidate vaccine development.
Sperm cells activate 90% of their genes, a pattern seen in other species, to repair DNA before passing it to the next generation. This process may influence the evolution of specific genes, with unexpressed genes containing fewer DNA code errors.
Researchers have developed a technique to create high-resolution images of biological samples, revealing new molecules and their spatial distribution. The technique uses a powerful mass spectrometer to produce detailed visuals of the molecular makeup of animal tissue.
Researchers at UC San Diego School of Medicine identified genetic switches that determine whether or not liver cells produce collagen, leading to a potential therapeutic target for liver fibrosis. By manipulating these transcription factors, liver fibrosis progression can be addressed.
A new experimental vaccine for African swine fever has shown promising results, with both low and high doses being 100% effective against the virus when challenged 28 days post-inoculation. The vaccine was developed to combat the highly contagious and lethal ASFV-G strain, which has been devastating Eastern Europe and Southeast Asia.
Researchers discovered that a rise in pH within lysosomes causes iron depletion, leading to cell death and inhibition of proliferation. This finding has implications for understanding and treating diseases, including cancer.
The British Heart Foundation has announced four research projects competing for a £30 million award to tackle cardiovascular diseases. The projects include a soft robotic heart, a genetic cure for inherited heart conditions, a 'google map' of atherosclerosis, and next-generation health tech.
A new study reveals iridescence can act as highly-effective camouflage, increasing prey survival and explaining its evolution in many animal species. Researchers found that iridescent beetle models survived best against bird attacks, suggesting a clever strategy to confuse predators.
Post-SSRI Sexual Dysfunction (PSSD) affects sexually active individuals, causing genital numbing, loss of libido and emotional numbing. Pharmaceutical companies are now warning that these effects can last even after treatment stops.
Researchers propose combining fever resistance with temporary tolerance promoted by controlled hypothermia for studying and treating severe conditions like sepsis. This innovative concept aims to understand human physiology's integrated defense strategies against infection.
Research found subtle structural features of donated kidneys, such as scarring and hardening of vessels, are associated with shorter kidney lifespan after transplantation. These findings may help clinicians evaluate organ quality at time of donation and identify potential predictors of transplant failure.
Mayo Clinic researchers discovered subtle structural features in living donor kidneys that can predict transplant failure in recipients. These features include minimal scarring, hardening of vessels, and enlarged nephrons.