Researcher Erin Kelleher is studying how some individuals can tolerate genetic mutations caused by 'jumping genes,' which can lead to devastating effects on reproductive cells. Her work aims to understand the underlying mechanisms of bruno-dependent tolerance in fruit flies and its potential implications for tumor cells.
Researchers at Florida State University have created a new material for X-ray scintillators that uses an organic manganese halide compound, eliminating the need for lead or heavy metals. This breakthrough technology could pave the way for more affordable and sustainable X-ray detectors.
The study aims to examine the extent to which the AD&A Second Major programme equips students with key skills and competencies in the future accounting workplace. It will also measure students' learning outcomes and gather insights on how future programmes can be designed to equip students with necessary skills.
A new study by University of Utah researchers found a correlation between media coverage of weather and air quality, and transit ridership. The study suggests that favorable weather conditions and comfort are associated with increased ridership, while poor air quality may discourage usage.
Research shows that people with obesity are at higher risk of severe COVID-19 disease and mechanical ventilation. The study analyzed ICU patients and found a clear correlation between BMI and disease severity, with those with severe obesity facing the highest risk.
A team of Brazilian researchers has completed the sequencing of Frieseomelitta varia, a native stingless bee species with economic interest as a pollinator. The study reveals conserved ancestral traits and regulatory functions in noncoding RNAs linked to the workers' sterility, providing valuable insights into social insect evolution.
A new study finds that reef-building corals are being driven to extinction by warmer, acidifying oceans, while softer-bodied relatives like sea anemones will adapt and thrive. The findings suggest a silver lining for the diversity of these animals, which may persist and diversify in the face of climate change.
Two 14-year longitudinal studies found that people with disagreeable personality traits, such as being combative and manipulative, are not more likely to achieve power than those who are nice. In contrast, extroverts were the most likely to advance in their organizations based on sociability, energy, and assertiveness.
A large Australian-Dutch trial confirmed low-dose colchicine significantly reduced cardiovascular death, heart attack, and stroke in patients with chronic coronary disease. Colchicine was safe and well-tolerated over the long-term, making it a potential cornerstone treatment alongside aspirin and statins.
The Center for BrainHealth's Adolescent Reasoning Initiative has trained over 600 middle and high school teachers to reach 80,000 students, improving executive function skills. The initiative aims to develop problem-solving, reasoning, and innovating abilities in students.
Researchers have discovered that younger cycad seeds contain higher levels of neurotoxins, increasing the risk of exposure. The study provides new models for estimating seed age, adding clarity to future research and shedding light on the origins of a neurological disease prevalent on Guam.
Researchers found that prior exposure to powdery mildew makes plants more susceptible to subsequent disease. In experiments and in the wild, early infection facilitated later infection, with some pathogen strains promoting infections from later-arriving strains. The findings highlight the importance of understanding interactions among ...
A new study from CU Anschutz researchers has identified the cerebellum as a critical region for making fast `go-no go' decisions. The study used mice to investigate the molecular layer interneurons in the cerebellum, which were found to play a role in learning valence and determining whether something is good or not.
A study found that urban wood storks fared better than their natural counterparts during suboptimal conditions, exploiting urban resources to improve reproductive performance. They switched to anthropogenic food sources, including trash and amphibians, to supplement their diets.
Researchers developed a rapid COVID-19 molecular test and portable instrument using a simpler process called LAMP, which can detect the virus in 30 minutes. The test uses a small 3D-printed microfluidic cartridge that reacts with chemicals to produce fluorescent light.
New research at University of Nebraska-Lincoln suggests that faculty networks are insufficient to disseminate evidence-based instructional practices. Most innovation sharing occurs within a smaller group of frequent users, rather than across departments.
A new study found that obesity-related illnesses frequently occur in people with a BMI over 30, yet only 9% had obesity recorded as a cause of death. Researchers argue that obesity is not being accurately documented on medical certificates, highlighting the need for further studies.
The PARALLAX trial found that sacubitril/valsartan reduces NT-proBNP levels by 16.4% compared to individualised medical therapy, indicating improved heart failure severity. However, functional capacity was not improved, with no significant difference in six-minute walk distance between groups at week 24.
A joint study by University of Cologne researchers predicts the outcomes of combining certain antibiotics using mathematical models. The scientists found that interactions between antibiotics are often caused by bottlenecks in the translation cycle, allowing them to predict the effects of antibiotic combinations without trial and error.
Researchers developed a curcumin-functionalized endotracheal tube that inactivates up to 95% of bacteria when illuminated. This innovation may help prevent hospital-acquired infections and reduce the need for antibiotic treatment.
A new NYC study reveals a significant variation in obesity prevalence among Latino populations, with Mexicans and Puerto Ricans more likely to have obesity. The study suggests that standardised treatment may obscure unique risks among specific groups, highlighting the need for culturally tailored approaches.
Researchers have developed first-in-class inhibitors of the NSD1 protein, a key enzyme linked to several types of cancer. The lead compound, BT5, showed promising activity in leukemia cells with the NUP98-NSD1 chromosomal translocation.
The Singapore Global Restructuring Initiative aims to promote cooperation and cutting-edge research on corporate insolvency. The project explores how insolvency laws can minimize the economic effects of crises like COVID-19, facilitating entrepreneurship, innovation, and access to finance.
A new study identifies a specific gene's role in fertility, finding mutations in this gene are associated with early menopause. The researchers used genetic techniques to find genes involved with eye development and discovered the gene is essential for reproductive organs.
A study of 900 US residents found that conservatives tend to view industry-majority boards as making unbiased decisions, while liberals see them as promoting business interests. The authors suggest this politicization could impact scientific advice given to the government.
A study analyzing over 650,000 hip replacement patients found that consistent use of reliable implants is a key factor in long-term success, not surgeon skill. The findings suggest that patients should ask their surgeons about the long-term evidence of an implant's effectiveness.
Researchers discovered that rhodochrosite can be photooxidized by UV light under anoxic conditions, suggesting a possible alternative to biological catalysts for oxygenic photosynthesis. This finding provides insight into the evolution of oxygenic photosynthetic organisms on Earth.
Researchers at Tufts University found that warning witnesses about the threat of misinformation can significantly reduce its negative impact on memory. The study revealed that warnings can protect memory from misleading information by influencing reconstructive processes during memory retrieval.
Researchers at FEFU are working on genetically modified models of brain tumors to understand the role of IDH1 and TP53 gene mutations. They plan to create laboratory models of these mutations to develop new diagnostic markers and test antitumor compounds, potentially leading to personalized therapy for glioma patients.
A team of scientists found that dodder parasites eavesdrop on their host plants' flowering signals to synchronize their own flowering. This allows the parasite to optimize its reproduction and increase its fitness.
A new study has quantified the extent of human development in oceans for the first time, mapping an area of approximately 30,000 square kilometers modified by human construction. This footprint is comparable to urbanized land and greater than some natural habitats like mangrove forests and seagrass beds.
The European Union will impose new nutritional requirements for total diet replacement (TDR) products, which threaten their commercial viability. The new rules require higher protein content and essential fatty acids, leading to reduced shelf-life and organoleptic properties.
The RACE trial demonstrated that adding Eltrombopag to standard immunosuppressive treatment increases response rates in patients with Severe Aplastic Anaemia. The study found significant improvements in complete response rates, sustained at 6 months, and showed Eltrombopag was generally well-tolerated.
The EXPLORER-HCM trial demonstrated that mavacamten significantly improves exercise capacity, symptoms, and quality of life in patients with obstructive hypertrophic cardiomyopathy. The treatment was found to be generally well-tolerated, with a favorable safety profile.
Researchers discovered dodder plants synchronize flowering with host plants by eavesdropping on their FT signaling protein. This unique behavior allows dodders to thrive by parasitizing diverse hosts without fixed flowering times.
The EAST-AFNET 4 trial found that early rhythm control therapy reduces cardiovascular complications and death in patients with atrial fibrillation. Rhythm control therapy delivered soon after diagnosis can improve outcomes, including reduced risk of severe cardiovascular complications.
Researchers at Champalimaud Centre for the Unknown discover that changes in sex cells' nutritional requirements make female flies crave sugar, affecting their food choice and fertility. The study's findings suggest a novel mechanism by which metabolism controls feeding behaviour, potentially relevant to human fertility.
A new study aims to assess the safety of a monthly dapivirine ring and daily oral PrEP in breastfeeding women, who are at high risk of HIV infection. The study, called B-PROTECTED, will enroll up to 200 mothers and their babies in Malawi, South Africa, Uganda, and Zimbabwe.
A new manganese-based single-atom catalyst has been developed, exhibiting high Faradaic efficiency and current density in electrochemical CO2 reduction. The catalyst outperforms all reported Mn SACs, paving the way for low-cost and efficient conversion of CO2 into useful chemicals.
A new study from North Carolina State University and Virginia Commonwealth University explores the extent to which fathers who don't have custody are involved in their children's lives. The research highlights three key factors: self-efficacy, relationships with caregivers, and the father-child relationship.
Researchers at Stellenbosch University and the University of Plymouth have successfully used unique signature whistles of individual bottlenose dolphins off Namibia's coast to estimate population size and track movement. The method, which marks a first for acoustic monitoring, yielded promising results and has potential applications fo...
A new study from the University of Colorado School of Medicine reveals that asymptomatic Chagas patients are at a high risk of developing cardiomyopathy, a progressive heart disease. The risk more than doubles among patients with acute infections, according to the study published in JAMA Network Open.
Researchers have discovered a way to make staple foods resistant to flooding triggered by climate change. By manipulating enzymes that control plant responses to low oxygen levels, scientists hope to create flood-tolerant crops that can help mitigate the devastating impact of extreme weather events on food production.
The HOME-PE trial found that home management is safe and effective for selected patients with acute pulmonary embolism. Using the Hestia criteria or sPESI score, over 30% of patients can be treated at home with a low rate of complications.
The Singapore Spacer project uses Wi-Fi signals to identify high human traffic areas, providing insights for safe environments in universities and commercial spaces. The system aggregates data over time to inform decision-makers on the effectiveness of policies.
Researchers found that individuals with reduced biological arousal before the onset of COVID-19 exhibited more symptoms of post-traumatic stress disorder compared to those with higher responses. The study suggests that lower heart rate reactions may be a unique biomarker for mental health outcomes.
A majority of surveyed US-based Republicans agree that traditional American values are disappearing, driven by ethnic antagonism and concerns about discrimination against Whites. The strongest predictor of these sentiments is ethnic antagonism, which erodes commitment to democracy.
A PET brain imaging study found that low aromatase levels in the amygdala are associated with higher BMI and lower self-control. The results suggest a novel method for characterizing estrogen's role in obesity and impairments in self-regulation.
The EAT-Lancet Report proposes a universal healthy reference diet rich in fruits, vegetables, and whole grains, but implementing this change requires unprecedented global cooperation. Policymakers must prioritize food systems as a top development agenda to realize the recommendations laid out in the report.
A new quantitative method assesses the effects of ingested plastics on individual and population levels in sea turtles, potentially impacting growth, reproduction, and survival. The study demonstrates a crucial step towards conservation and mitigating the negative effects of plastic waste on marine ecosystems.
Researchers created silicon-based batteries with improved stability and capacity, allowing for faster charging times and increased efficiency. The breakthrough could enable the use of lighter batteries in spacesuits and satellites, reducing mission costs and increasing energy storage capabilities.
A large study of over 260,000 participants found no evidence that blood pressure lowering drugs increase the risk of cancer. The research analyzed data from 31 trials and investigated five antihypertensive drug classes, including ACE inhibitors and beta blockers.
A recent study published in Nonprofit and Voluntary Sector Quarterly found that individuals perceived as more attractive are more likely to exhibit generous behaviors, while givers are rated as more attractive. This research challenges the conventional notion that physical attractiveness is solely linked to personal qualities.
A new study published at ESC Congress 2020 suggests that body mass index (BMI) is a more powerful risk factor for developing type 2 diabetes than genetic predisposition. Researchers found that individuals with a higher BMI were more likely to develop diabetes, regardless of their genetic risk level.
The FDA's emergency use authorization process for COVID-19 vaccines was criticized for its speed and lack of rigor. The researchers propose four reforms to enhance accountability and transparency in drug authorizations and approvals, including improved risk assessment and post-marketing surveillance.
A two-year project is prototyping miniature fitness trackers and environmental sensors to monitor lobsters' health and shipping conditions. The devices aim to reduce mortality and improve survival in the lobster supply chain, valued at nearly half a billion dollars annually.
Researchers discovered a metabolic adaptation in nerve cells that allows them to counteract degeneration and promote survival. This 'metabolic rewiring' involves the activation of the Krebs cycle anaplerosis pathway, which makes neurons resistant to progressive damage.
Researchers found significant correlations between stationary wave strength and tropical cyclone activity, with strong waves modulating TC frequency and altering atmospheric conditions. The study's hemispheric perspective on TC variability offers insights into improving future projections of TC activity in a warming climate.
African forest elephants' trail networks benefit humans and local communities. Biological anthropology plays a crucial role in conservation by considering human knowledge and needs alongside species protection.
A University of Cincinnati researcher is studying how cancer treatments could impact patients who also have COVID-19 and blood clots. The study aims to understand the thrombotic risk posed by certain cancer treatments and hopes to contribute data that could prevent complications for millions of patients.