The POPular TAVI trial found that aspirin alone significantly reduced bleeding rates compared to aspirin with clopidogrel after TAVI. Aspirin therapy was also superior for secondary outcomes, including non-procedural bleeding and thromboembolic events.
A clinical trial found that patients with IDH-mutant high-risk LGG, regardless of codeletion status, receive a survival benefit from adding postradiation chemotherapy. The study supports the use of WHO-defined molecular subgroups in predicting response to treatment.
A pharmacist-led telemonitoring program has been shown to lower blood pressure and reduce the risk of heart attacks, strokes, and other cardiovascular events. The study found a significant reduction in serious cardiovascular events among patients enrolled in the telemonitoring group compared to those receiving routine primary care.
Infants as young as two years old exhibit increased brain flexibility, a key factor in cognitive development, according to UNC-Chapel Hill researchers. This emerging neural ability enables early learning of new motor skills and supports the maturation of higher-level cognitive processes.
Scientists have developed biocompatible TeSex nano-alloys that eliminate toxicity and enhance theranostic performances for precision medicine. The nano-alloys enable high-efficacy photothermal therapy under multimodal imaging guidance.
Exercise-based stress relief is linked to increased galanin levels in the brainstem, which improves stress resilience. This study found that mice with access to an exercise wheel displayed reduced anxious behaviors and elevated galanin levels in response to a stressful event.
The HCA|Organoid project will establish an open access Organoid Cell Atlas, enabling future discovery-driven and translational research on rare genetic diseases, complex multifactorial diseases, and cancer. The project will derive and comprehensively characterize human brain and colon organoids from 100 individuals each.
A study reveals that amyloid protein alpha-synuclein found in Parkinson's brains is also present in skin cells producing melanin, modulating protein fibril formation and suggesting a molecular link between the two diseases. The discovery may explain the observed association between Parkinson's disease and melanoma.
The introduction of pneumococcal conjugate vaccine PCV13 has significantly reduced socioeconomic disparities and Black-white-based racial disparities for invasive pneumococcal disease. The study found a large decrease in the overall incidence of pneumococcal disease and markedly reduced race-based disparities.
AUC Riverside researchers find ephrin-B1 regulates E/I balance in hippocampus, leading to seizures and social abnormalities. The study provides new insights into mechanisms behind neurodevelopmental disorders.
Researchers used satellite imagery to detect non-native Amur honeysuckle in urban parks and cemeteries, achieving 82% accuracy. The method provides a cost-effective solution for ecological restoration, allowing for targeted removal of invasive species.
Dr. Hon's article explores the risk of deep vein thrombosis in individuals with spinal cord injury, suggesting screening on admission may be advisable to identify at-risk patients. The Bors Award recognizes her contributions to advancing spinal cord injury care and research.
Researchers developed a method to create flexible micro LEDs that can be detached from their substrate and attached to various surfaces. This technology aims to enable bendable, wearable electronics with high resolution.
The discovery of radio jets in the Phoenix Galaxy Cluster suggests that a supermassive black hole is actively heating intra-cluster gas, preventing star formation. This finding has significant implications for our understanding of galaxy evolution and coevolution.
A study from American University found that a diet low in glutamate and high in nutrients reduced symptoms in US veterans with Gulf War Illness. The study showed significant reductions in overall symptoms, pain, and fatigue after one month on the diet.
A recent study by researchers from the Hinda and Arthur Marcus Institute for Aging Research found that older adults living in disadvantaged neighborhoods are two times more likely to experience delirium after surgery. Delirium is a clinical syndrome characterized by acute decline in cognition, which can present as inattention, disorien...
Researchers found that a Mediterranean ketogenic diet can alter specific gut fungi associated with higher Alzheimer's disease risk. The study suggests that this dietary approach may help reduce harmful fungi in the gut, potentially leading to improved mental health outcomes.
Researchers used publicly available cell phone location data to analyze activity across up to 2,740 counties in the US. They found that counties with a greater decline in workplace cell phone activity showed lower COVID-19 infection rates, suggesting this data can be used to estimate growth rates and inform decision-making.
Children born to mothers with PCOS are at a higher risk of psychiatric and neurodevelopmental disorders, including emotional problems, autism, ADHD, and delayed development. The study found a significant link between PCOS and increased risk of neuropsychiatric disorders in offspring, independent of maternal obesity.
Cardiac fibroblasts can be directly reprogrammed to form beating heart muscle cells on soft surfaces that match the elasticity of native myocardium. This approach shows increased functional maturation and spontaneously beating iCMs, with implications for treating heart failure and myocardial infarction.
The COVID-19 outbreak has caused immense problems at a macro socioeconomic level and has taken a toll on the physical and mental well-being of individuals worldwide. Caregivers, physicians, and others directly dealing with patients are likely experiencing trauma consequences and burnout syndrome.
A new study suggests that young women who experience a heart attack may have more favorable long-term outcomes compared to men. The research found that second heart attacks were less frequent in women and they were more likely to have healthy arteries. However, women were also at higher risk of stroke compared to men.
Scientists have developed a low-temperature resisting hybrid electrolyte for aqueous zinc-based batteries (ZBBs), exhibiting high zinc-ion conductivity at low temperature. The new electrolyte improved the performance of ZBBs, enabling high energy densities, power densities and long-cycle life at -20°C.
Researchers have developed a new method for creating multicolor single-mode microlasers capable of emitting over the full visible spectrum. The lasers are achieved through heterogeneously coupled cavities constructed with three spherical microcavities and distinct gain media.
A RUDN University linguist found a potential correlation between the number of COVID-19 cases in a country and the presence of aspirated consonants in its main language. The study, published in Medical Hypotheses journal, suggests that languages like English with more aspirated consonants may lead to faster spread of the virus.
A new scoring system is proposed to diagnose COVID-19, taking into account epidemiological evidence, clinical symptoms, and investigations. This simple system can be calculated in minutes and helps classify suspected patients for further evaluation or isolation.
The ESC guidelines recommend imaging to identify underlying causes of heart attacks, including blood vessel tears. Treatment involves restoring blood flow with stents and blood thinners, as well as lifestyle modifications such as smoking cessation and exercise.
The European Society of Cardiology recommends an individualized care plan for patients with atrial fibrillation, incorporating symptom management, cardiovascular optimization, and lifestyle modifications. Patients should be informed about the implications of detecting atrial fibrillation and receive treatment to prevent stroke.
Patients with type 2 diabetes experience significant reductions in heart attack risk and mortality when starting medications to prevent cardiovascular disease. The study found that the risk was reduced by 61% for heart attacks and 41% for death over a 15-year period.
Adults with congenital heart disease require lifelong management, including regular appointments, pregnancy planning, and exercise recommendations. The ESC guidelines provide guidance on diagnosis, treatment, and support to help these individuals lead normal lives.
The European Society of Cardiology has launched new guidelines on sports cardiology and exercise in patients with cardiovascular disease. The guidelines recommend regular exercise, including strength-building and aerobic activities, to prevent heart disease and improve overall health.
New research led by the Singapore-ETH Centre reveals that mangrove conservation and restoration efforts have slowed down deforestation and preserved carbon stocks globally. The study found a 1.8% net loss of mangrove carbon stocks between 1996 and 2016, significantly lower than previous estimates.
The COVID-19 crisis has exposed Australia's National Broadband Network (NBN) shortcomings, with over 1 million households lacking internet access at home. The Flinders University researchers found that the NBN rollout prioritized politics and commerce over equity considerations, leading to unequal access to high-speed broadband services.
Researchers discovered fossil trees on Peru's Central Andean Plateau, revealing a more humid ecosystem than predicted by climate models. The findings support the hypothesis that tectonic uplift occurred in rapid pulses, shaping the region's climate and vegetation.
A new study by the American Academy of Sleep Medicine found that atheists and agnostics sleep better than Catholics and Baptists. 73% of atheists reported getting seven or more hours of sleep per night, compared to 63% of Catholics and 55% of Baptists.
Researchers have discovered a unique binding mode that allows bacteria to stick to cellulose fibers in the human gut, enabling them to withstand shear forces. This breakthrough sheds light on the microbiome and its relationship to human health, with potential applications in bio-based medical superglues.
Adrienne Bryant Godwin receives funding to create a performance project exploring human migration through the eyes of four children. The project aims to reflect on global migration issues using artistic expressions, suitable for audiences aged 10 and older.
A new physiological test for diagnosing autism spectrum disorder (ASD) has shown promise, accurately identifying 124 of 131 children with ASD regardless of co-occurring medical conditions. The test measures metabolites in a blood sample and predicts diagnosis with minimal impact from other health issues.
The NASA Terra satellite captured an infrared image of cloud top temperatures in Tropical Storm Hernan, showing its final burst of strength. The storm's powerful thunderstorms had coldest cloud top temperatures as low as minus 80 degrees Fahrenheit near the center.
A new study from the University of Jyväskylä found that women scoring high in neuroticism reported less physical activity and had lower leisure time physical activity. High extraversion was linked to higher leisure time physical activity in middle-aged women.
A cardiac biomarker was found to have stronger associations with kidney disease progression than blood pressure in both diabetic and nondiabetic individuals. Higher levels of NTproBNP, urine NGAL, and troponin T were linked to increased rates of CKD progression.
Tropical cyclones are composed of hundreds of thunderstorms, and NASA's Infrared Data Reveals Where the Strongest Storms Are Located. The strongest storms have coldest cloud top temperatures, with some reaching minus 80 degrees Fahrenheit near Iselle's center.
A new study from Oregon State University found that natural disasters alone are not enough to motivate local communities to engage in climate change mitigation or adaptation. Policy change appears to depend on a combination of factors, including fatalities, media coverage, and community politics.
A study of 495 Portuguese adults aged 18-24 found a strong link between smartphone use and feelings of panic, anxiety, and obsession. Researchers discovered that those who experienced nomophobia (fear of being without their phone) scored higher on obsession-compulsion tests.
Researchers develop Salvinia-like slippery surface with stable water/air contact line, exhibiting increased stability against pressure and impact. The surface also enhances the mobility of water drops and reduces hydrodynamic drag.
Researchers used high-resolution models to predict where marine heatwaves will occur and intensify, revealing stark regional variability. The study found intense heatwaves more likely off Tasmania's coast and along the US Gulf Stream's shoreline.
Research suggests children with no COVID-19 symptoms may still shed virus for weeks, making them potential key vectors. The study's findings also highlight the importance of understanding viral shedding in asymptomatic patients and its impact on herd immunity.
Researchers from Iowa State University have discovered that two seemingly unrelated responses in corn plants work together to mitigate damage caused by heat stress. The unfolded protein response and heat shock response, which operate in different parts of plant cells, collaborate to protect the crop from stress.
A new study found that accurately simulating ocean current variations during El Niño events is crucial for reducing climate prediction uncertainty. When models simulate these processes correctly, they show increased asymmetry between El Niño and La Niú, similar to natural climate swings.
A new study found that infants from households with very low food security are more likely to have above-average body mass indices, higher fat levels, and other measures indicating greater obesity risk. This association suggests that household food insecurity may be especially hazardous for infants.
The research reviews recent progress on ridge subduction, a key geological process involved in the generation of arc magmatism, material recycling, and metallogenesis. It highlights the significance of ridge subduction in modern oceanic plate tectonics and identifies areas for future research.
Researchers found that CNOT3 protein silences genes that cause insulin-producing cells to malfunction, leading to diabetes. Knocking out CNOT3 in mice results in the development of diabetes due to the activation of normally silenced genes.
Tropical Depression Laura is generating heavy rain and triggering watches across the eastern U.S., with a risk of tornadoes in parts of Mississippi, Tennessee, and southern Kentucky. The depression is moving east-northeast at 20 mph, expected to continue along the Ohio Valley through tonight.
A new study reveals that climate change could lead to a shift in malaria transmission patterns across Africa, with southern Africa experiencing increases in suitable areas and West Africa seeing decreases. River corridors are identified as year-round hot spots of malaria transmission.
Researchers have developed a groundbreaking process for multi-material 3D printing of lifelike heart valve models, which can be used to improve surgical outcomes in thousands of patients worldwide. The patient-specific organ models include integrated sensors that provide electronic pressure feedback to guide and optimize valve placement.
A large European study shows that combining lipid-lowering therapies can further reduce cholesterol levels and improve health outcomes for high-risk patients. Current clinical guidelines are not always followed in practice, highlighting a need for better cholesterol management across Europe.
Scientists have discovered a way to control the pitch of biopolymers, leading to the creation of structural colors in liquid marbles. The colors change in response to environmental factors such as heat, pressure, or chemicals, making this technology promising for bio-based sensors and soft photonic elements.
Josef Uyeda aims to bridge the gap between short-term evolution studies and long-term outcomes using computational tools and resources. He will analyze existing datasets to understand how species adapt to climate change and extinction.
Researchers developed a saliva-based diagnostic method for COVID-19, detecting more cases than standard nasopharyngeal swab tests. The new approach has several advantages, including reduced need for PPE and trained staff.
Researchers found that host skin and intestinal T cells survive conditioning regimens and continue to perform their normal functions. These T cells can become activated by donor white blood cells, leading to graft-versus-host disease.