Genome Editing

MDC researchers greatly increase precision of new genome editing tool

Researchers at the Max Delbrück Center for Molecular Medicine have discovered a method to increase the efficiency of precise genetic modifications using the CRISPR-Cas9 technique. By inhibiting a key enzyme, they achieved an eightfold increase in precision, paving the way for more accurate gene editing applications.

A new model organism for aging research: The short-lived African killifish

Scientists have created a new model organism for studying aging in the naturally short-lived African turquoise killifish. The researchers developed a genome-editing toolkit, allowing them to rapidly manipulate genes and study aging-related diseases.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Seamless gene correction of beta-thalassemia mutations in patient-specific cells

Researchers successfully corrected disease-causing mutations in cells from patients with beta-thalassemia using CRISPR/Cas9 technology. The corrected cells showed restored expression of hemoglobin and could differentiate into mature blood cells.

Editing the genome

Researchers developed genome-scale editing tools, replacing instances of a stop codon in E. coli with another, creating novel cell strains with increased functionality and safety. The new method, CAGE, surpasses current methods by two orders of magnitude.