Articles tagged with Genome Evolution
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scientists created induced pluripotent stem cells (iPSCs) from chimpanzee and bonobo skin cells to compare with human iPSCs. They found differences in the regulation of jumping genes, which may have shaped the evolution of their genomes.
Researchers have closed the genetic map of the fungal kingdom by sequencing the genome of Pyronema confluens, a basal filamentous ascomycete. The study reveals key differences between this species and higher ascomycetes, shedding light on the evolution of mating type genes and light-activated processes.
Genome sequencing of MERS-CoV identified multiple chains of infection, indicating human-to-human transmission is more complicated than expected. The study suggests additional sources of the virus, such as undetected carriers, are involved in its spread.
Researchers found strong selection for MC1R gene variants in South Europeans, associated with fair skin and increased melanoma risk. The V60L allele variant has been linked to both benefits and drawbacks, highlighting evolutionary trade-offs.
Researchers found nearly 200 genomic regions with similar genes in bats and dolphins, indicating convergent evolution of echolocation. The study used a massive genome-wide survey to identify genetic signatures consistent with convergence in 'hearing genes',
Researchers at Indiana University found that asexual lineages are more susceptible to extinction due to fast-paced gene conversion processes. This process exposes pre-existing deleterious recessive mutations, contributing to the decline of asexual populations.
Researchers discover REVs originated in mammals and spread to birds through medical intervention, revealing an unusual evolutionary history. The study suggests REVs were introduced into poultry and subsequently into avian cell culture systems, impacting wild birds and domestic poultry.
The rotifer genome shows evidence of gene conversion and horizontal gene transfer, which help maintain healthy genes and viable lineages. This reproductive strategy, absent in most animals, may mimic some aspects of sex and provide a layer of protection from mutations.
Researchers at Princeton University discovered that evolution is driven by a group of beneficial mutations, including genetic hitchhikers. About five to seven specific mutations are needed for an organism to succeed, rather than just one mutation.
Jason H. Moore, Professor at Dartmouth College, has been recognized for his expertise in translational bioinformatics and personalized medicine. He presented his research on Alzheimer's disease at the Third Indonesian-American Kavli Frontiers of Science Symposium.
Australian scientists discovered that up to 30% of the human genome is conserved in RNA structure, contrary to previous estimates. This finding suggests that non-coding DNA may play a crucial role in regulating gene expression and development.
A 700,000 year old horse's genome has been sequenced, revealing major genomic changes over the last 700,000 years of evolution. The study provides unprecedented details on the genetic makeup of modern horses and sheds light on the origin of Przewalski's Horse population.
The study reveals a large block of genes from wild relatives are present in domestic tomatoes, affecting the genome in unexpected ways. Genes associated with fruit color and drought tolerance show rapid evolution among domesticated and wild varieties.
A 700,000-year-old horse fossil found in the Yukon permafrost has provided new insight into equine evolution, revealing a genome that falls within a line of modern horses and Przewalski's Horses. The study also showed episodes of severe demographic fluctuations in horse populations linked to major climatic changes.
A recent study published in the Proceedings of the National Academy of Sciences found that planktonic bacteria have reduced their genomes to optimize growth and adaptability. This adaptation allows these microorganisms to efficiently utilize diverse energy sources and survive in the ocean's complex ecosystem.
A recent study has revealed a distinct evolutionary path for bacteria living in animals, including the mealybug's complex relationship with bacteria. The findings suggest that gene transfer from one bacterium to another plays a crucial role in maintaining this relationship.
A Cornell University study provides evidence for the 40-year-old hypothesis that regulation of genes must play an important role in evolution. The researchers found that transcription factor binding sites show considerable amounts of positive selection, suggesting adaptation in these regulatory elements.
Researchers have sequenced the genome of Emiliania huxleyi, a microscopic plankton species that forms the chalky skeletons of the White Cliffs of Dover. The study reveals unexpected features in the algae's genetic code, which may hold secrets to producing nutritional supplements and biofuels.
Scientists discovered a set of core genes that mix and match with variable genes allowing Emiliania huxleyi to adapt to different environments. This discovery may help understand how rising industrial carbon emissions affect climate and ocean health.
Researchers at McGill University found that Leavenworthia plants regained self-pollen recognition function by taking over two other genes. This study suggests that the loss of complex traits may not always be irreversible in plants.
A recent study published in Nature Genetics reveals that self-fertilizing plants like Red Shepherd's Purse accumulate harmful mutations over time, reducing genetic diversity. This can lead to extinction, highlighting the importance of preserving crop genetic variation to avoid yield losses due to mutation accumulation.
A study has shown how a relatively young gene can acquire an essential function and become crucial for an organism's survival. Researchers found that the novel essential gene in fruit flies, born via gene duplication, acquired its role through stepwise changes over 15 million years.
Researchers at Rutgers University have discovered the biological process of how corals create their skeletons, which form massive and ecologically vital coral reefs. The study found that specific proteins produced by corals can form limestones, even in more acidic water, suggesting coral reefs may survive ocean acidification.
Researchers from CNIO describe how a genetic duplication 500 million years ago led to the evolution of the ASF1b gene, essential for proper cell division and related to breast cancer. The study's findings highlight the importance of studying molecular history to understand gene adaptation in cancer.
Researchers found that Drosophila subobscura flies acquired genetic variants tolerant to heatwaves, leading to high reproductive success for resistant genotypes. The study provides evidence of genome adaptation to temperature changes and highlights the resilience of certain organisms to environmental disturbances.
Scientists have mapped Norway spruce's massive genome, identifying 29,000 functional genes. The seven times larger genome is attributed to 'genome obesity' from repetitive DNA sequences, a challenge in conifers.
A study found that shorter plants have faster-changing genomes and evolve as much as five times faster than taller ones. This is due to the accumulation of genetic changes in actively-dividing cells at the tip of plant shoots.
A Rice University study found that regulatory patterns in E. coli cells can arise from mutation, genetic drift, and neutral evolution, challenging the idea that environmental factors drive such patterns. The researchers generated computer models of random regulatory networks, which evolved through millions of generations without progra...
Researchers identified a case of spatial and temporal conflict in regulating the ventral neurons defective gene, which must be precisely regulated for proper nervous system specification. The study shows that an additional input from a complementary gradient of the Dpp morphogen solves conflicting temporal and spatial responses.
A Texas A&M University research team has successfully sequenced the complete genome of a Scarlet macaw, providing new insights into avian evolution and conservation. The genome analysis revealed significant differences between the macaw and chickens, shedding light on genetic factors influencing longevity and intelligence.
The Utricularia gibba genome, smallest sequenced from a complex plant, contradicts the notion that vast quantities of noncoding DNA are crucial for complex life. The bladderwort has purged most of its genetic material, including noncoding 'junk' DNA, while maintaining a functional set of genes similar to those of other plant species.
Harmit Malik, an evolutionary geneticist at Fred Hutchinson Cancer Center, has been selected as a Howard Hughes Medical Institute investigator to study genetic conflict and its role in driving evolutionary change. His research focuses on understanding the competition between genes and proteins with opposing functions.
Researchers discovered a previously unrecognized organelle gatekeeper function in C. elegans, which restricts the flow of Golgi and endosomal organelles into axons. Additionally, two studies identified novel players in meiotic silencing by unpaired DNA in Neurospora, providing insights into genome integrity and transmission.
Researchers sequenced soft-shell turtle and green sea turtle genomes to study evolutionary history and development of unique anatomical features. They found evidence that turtles diverged from archosaurians around 267.9-248.3 million years ago and developed superior olfaction ability.
Researchers used a method to test for evolutionary adaptation in genes regulated by FOXP2, a key factor in human development and language. The study found strong evidence for selection of FOXP2-regulated genes in European populations, highlighting their potential roles in neural cell development and immunity.
The coelacanth genome provides valuable clues for biologists studying the evolution of vertebrates, with key genes involved in immunity, nitrogen excretion, and limb development implicated in evolutionary transitions. The study offers a comprehensive look at the coelacanth's place in our evolutionary history.
Researchers at A*STAR's Institute of Molecular and Cell Biology have decoded the genome of the African coelacanth, revealing genetic changes that enabled aquatic animals to transition to life on land. The study provides valuable insights into the evolutionary history of the species and its adaptations.
The coelacanth genome confirms genes evolve more slowly than in other organisms, suggesting a specialized environment has led to minimal change. The study also sheds light on the water-to-land transition, identifying key genetic regions associated with tetrapod innovations and immune system adaptations.
Researchers have decoded the platyfish genome, revealing insights into cancer development and complex behaviors. The study found altered genes involved in live-bearing birth and unique molecular changes, shedding light on the evolution of these traits.
The tulip tree's mitochondrial genome has remained largely unchanged since the dinosaurs, providing a 'molecular fossil' with preserved ancestral gene clusters. The slow mutation rate allows researchers to estimate the ancestral angiosperm mitochondrial genome contained 41 protein genes.
Researchers found genes in turtles that become more active in low-oxygen conditions, including one 130 times more active than in humans, which may improve oxygen-deprivation treatment. Turtles' long lifespan may come from silencing 'life-shortening' genes, similar to those present in humans.
The study reveals that turtles activate existing genes in new ways to adapt to oxygen deprivation, which may lead to improved treatments for human heart conditions. The research also highlights the importance of preserving turtle diversity due to their slow evolution rate and declining global populations.
This April issue of the Genetics Society of America's journal features research on genotyping-by-sequencing, a novel gene silencing system in fungi, and the role of protein chaperone HSP90 in facilitating gene duplicate divergence. Additionally, studies explore genome integrity and RNA editing in mice.
Researchers found that head-on collisions between replication and transcription machineries lead to faster mutations in genes on the lagging strand. This accelerated mutation rate may help bacteria adapt to environmental changes, but also increases structural variations in proteins.
The western painted turtle genome shows a slow evolution rate compared to humans and pythons, with 19 brain genes and 23 heart genes expressed in low oxygen conditions. The study reveals potential insights into human health disorders related to anoxia and hypothermia.
Two studies published in Nature provide unprecedented insights into the biology of wheat, shedding light on its adaptation and domestication. The research reveals the importance of transposable elements and microRNAs in shaping the genome, as well as their potential applications in improving crop yields and disease resistance.
Researchers sequenced and analyzed the genomes of peregrine and saker falcons, uncovering key adaptations that enable their success as predators. The study sheds light on the evolution of these iconic birds' morphological, physiological, and behavioral traits.
Two recent studies published in Nature provide unprecedented insights into the biology of wheat, shedding light on its adaptation to diverse climates and improving grain quality. The research revealed the role of repeat expansion in genome size during evolution and identified key genes for abiotic stress response, providing a valuable ...
Protein networks are essential for organisms, and their evolution is a fascinating research question. Researchers have reconstructed ancient protein networks, finding that present-day networks can be explained by the mechanism of duplication and divergence, supporting the interpretation of genome sequence data.
Researchers have found that nine separate mutations within a single gene in deer mice result in changes to their camouflage, illustrating the power of small genetic changes. The study suggests that natural selection acts on many small genetic changes to produce rapid and dramatic adaptations.
Researchers have sequenced the wild rice genome, revealing the silencing of retrotransposons and massive internal deletions that led to its compact genome. The study also found expanded gene families in cultivated rice due to tandem duplications and gene movements.
The genome of extremophile red alga Galdieria sulphuraria reveals horizontal gene transfer from bacteria, allowing it to survive battery acid and toxic metals. This discovery provides new insights into evolution and potential applications in biotechnology.
Researchers at A*STAR's Genome Institute of Singapore have developed a novel technique called LoFreq, which allows them to detect microbe and cancer cell mutations in real-time. This breakthrough enables scientists to catch the development of resistance early on and investigate the effectiveness of new drugs.
The March 2013 issue of Genetics journal highlights several key findings, including a study on oocyte-expressed genes that support early cloned embryo development and the role of cytoskeletal proteins in controlling clone quality. Additionally, research on self-incompatibility genes in Arabidopsis thaliana reveals the structural and fu...
Scientists at OU, Japan, Germany, US, Canada, and Great Britain collaborate to sequence the sea lamprey genome, providing insights into vertebrate evolution and character traits. The study reveals two whole-genome duplication rounds in vertebrates, shedding light on the origins of myelin and paired appendages.
Researchers found that identical mutations led to the evolution of specialized physiologies in three different populations of E. coli. The study suggests that negative frequency dependence plays a key role in driving diversification, and highlights the potential for predictability in evolutionary processes.
Researchers investigated genetic changes responsible for species divergence, developed new approaches to Drosophila genome manipulation, and found minimal effect of gene clustering on expression in bacteria. These findings shed light on mechanisms driving speciation and gene regulation.
Scientists studied evolutionary rates of nearly 20,000 human genes and found that genes involved in the same biological pathways change their rate of evolution in parallel. This signature can help identify partner genes that may work together in biochemical pathways, providing clues to their function.
Researchers found a single mutation in the EphB2 gene responsible for creating head crests in pigeons. The study reveals insights into bird evolution and provides new tools to understand animal diversity.
A study by HITS researchers found that most proteins evolved to fold faster, with a 'big bang' of complex structures emerging 1.5 billion years ago. The study suggests that faster folding speeds may make proteins less susceptible to aggregation.