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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Unlocking the biochemical treasure chest within microbes

A team of microbiologists developed CRAGE to study and produce secondary metabolites, compounds produced by microbes for internal and external messaging. The technique allows scientists to access these compounds more readily than before, filling significant gaps in our understanding of microbial interactions.

Like an instruction manual, the genome groups genes together for convenience

Scientists identified over 11,000 families of grouped genes in genomes of different species, with a third being part of conserved clusters. The study found that natural selection favors gene organization, making it easier to regulate genes, and that horizontal transfer may be less common than previously thought.

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Parasitic plants use stolen genes to make them better parasites

Dodder parasitic plants have stolen over 100 functional genes from their host plants, contributing to their ability to latch onto and steal nutrients. The transferred genes also produce small segments of RNA that may act as weapons to silence host defense genes.

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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Fungus senses gravity using gene borrowed from bacteria

The pin mold fungus Phycomyces blakesleeanus uses a gene from bacteria to create large gravity-sensing crystals that help it grow upright. Genetic analysis reveals the role of horizontal gene transfer in acquiring this unique trait, providing insights into the evolution of adaptation.

Breakthrough in determining ages of different microbial groups

Scientists have developed a new method to investigate the timing and co-evolution of microbial groups by analyzing horizontal gene transfer among ancient microbes. This breakthrough provides relative age constraints for several microbial groups without reliable fossil evidence, including the Archaea.

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Parasitic plants may form weapons out of genes stolen from hosts

Researchers discovered that parasitic plants, such as broomrapes, can transfer genes from their host plants, making them more invasive and resistant. This horizontal gene transfer may lead to the development of resistant host plants to combat crop loss caused by these weeds.

Surprising role of bacterial genes in evolution

Researchers have demonstrated that horizontal gene transfer may play a major role in compensating for genome reduction in endosymbionts. This process involves the acquisition of genes from neighboring bacteria through horizontal gene transfer, which fills gaps in organelle-localized biosynthetic pathways.

Stick insects produce bacterial enzymes themselves

Researchers discovered that stick insects can produce microbial enzymes, including pectinases, which degrade plant cell walls. This 'horizontal gene transfer' occurred between 110 to 60 million years ago, allowing the insects to break free from their microbiome's digestive capabilities.

Scientists map the genome of the common bed bug

Researchers have successfully mapped the genome of the common bed bug, identifying 805 possible instances of genes transferred from bacteria. The findings suggest that these genes, such as a patatin-like gene, could become effective targets for pest control.

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The life and times of domesticated cheese-making fungi

Researchers have identified crucial metabolic genes that enable cheese-making fungi to thrive on cheese, while also raising concerns about food safety. The study provides insights into the evolutionary history of these fungi and their ability to adapt to domesticated environments.

Sweet potato naturally 'genetically modified'

Researchers at Ghent University discovered that sweet potatoes contain genes from the bacterium Agrobacterium, which were likely introduced through horizontal gene transfer. The findings suggest that genetic modification also occurs in nature, and could have implications for our understanding of plant evolution.

Some genes 'foreign' in origin and not from our ancestors

Research published in Genome Biology found that humans and other animals have acquired 'foreign' genes from microorganisms, suggesting ongoing gene transfer. The study identified 17 previously-reported genes and 128 additional foreign genes in the human genome, related to metabolism, immune responses, and more.

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Making new species without sex

Scientists at Max Planck Institute have successfully generated new plant species through grafting, allowing for the transfer of entire genetic material between two species. The resulting plants exhibit improved growth rates and increased fitness compared to their parent species.

Ferns borrowed genes to flourish in low light

Ferns acquired a gene called neochrome from hornworts, allowing them to thrive in shaded environments. The transfer of this gene helped ferns diversify and flourish under the new canopy, outcompeting flowering plants.

Study of insect bacteria reveals genetic secrets of symbiosis

Researchers discovered a three-way symbiosis involving six different organisms, including the smallest known genome, and found evidence of horizontal gene transfer between bacteria and their hosts. This study sheds light on fundamental questions of life's origin and the role of symbiotic relationships in shaping organismal complexity.

Home toxic home

Researchers at Michigan State University have made a groundbreaking discovery about the survival mechanisms of primitive red algae. The algae's ability to thrive in hot and acidic environments lies in part in their membrane proteins, which are also found in human cells and hold promise for treating diseases.

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Parasitic plants 'steal' genes from their hosts

Researchers found that parasitic plant Rafflesia cantleyi has 'stolen' genes from its host Tetrastigma rafflesiae, including those related to respiration and metabolism. This horizontal gene transfer has replaced the parasite's own gene activity in three-quarters of the cases.

Stealing life's building blocks

Researchers found that parasitic flowers share large parts of their genome with host vines through horizontal gene transfer, and some borrowed genes are likely functional. The process may convey an evolutionary advantage to the flowers, which have replaced vertically inherited copies.

Discovery of jumping gene cluster tangles tree of life

A team of researchers at Vanderbilt University has discovered a large cluster of genes that appeared to jump directly from one fungus species to another, significantly strengthening the argument for a mosaic theory of evolution. The finding was made possible by comparing the genomes of nearly 100 species of fungi.

Scientists decipher 3 billion-year-old genomic fossils

A team of scientists at MIT has deciphered 3 billion-year-old genomic fossils using modern-day genomes. The study reveals that the collective genome of all life underwent an expansion between 3.3 and 2.8 billion years ago, resulting in 27% new gene families.

Aphids borrowed bacterial genes to play host

Research published in BMC Biology reveals that aphids acquired symbiotic genes from another species of bacteria via lateral gene transfer. The association between aphids and Buchnera is over 100 million years old and has evolved so that neither the bacteria nor the host can reproduce without the other.

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No sex, but plenty of gene transfer

Bdelloid rotifers acquire genes from bacteria, fungi, and plants through environmental DNA incorporation. This process may contribute to their speciation and adaptability.

Changing environment organizes genetic structure

A study by Deem and Jun Sun found that genetic information becomes increasingly modular when exposed to a changing environment and horizontal gene transfer. This modularity arises spontaneously due to selective pressure, resulting in complex biological structures.

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Lateral thinking produces first map of gene transmission

Researchers mapped how genes are shared between bacteria through lateral genetic transfer, a process where genes are transferred between unrelated organisms. The study reveals that this phenomenon is widespread and can occur even between distantly related organisms, contributing to the rapid spread of disease-causing bacteria.

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Trees, vines and nets – microbial evolution changes its face

A new map of microbial evolution reveals that more than 600,000 genes have been transferred horizontally among species over billions of years. This finding challenges the traditional tree-like representation of evolutionary relationships and highlights the importance of horizontal gene transfer in shaping microbial communities.

Map of life on Earth could be used on Mars

Researchers have developed a new map of life on Earth, which could be used to identify the potential for life on Mars. The map was created by tracing the evolutionary history of microorganisms using genetic sequencing data and shows that ancient microbes inhabited specific habitats, including hydrothermal systems.

Gene exchange between species is aided by parasitism

Indiana University researchers found that genes can move from plant parasites to host plants, establishing parasitism as a medium for horizontal gene transfer. The discovery complements previous findings showing the opposite process, and suggests that plant parasitism has been a key mechanism of gene exchange between species.

New cellular evolution theory rejects Darwinian assumptions

A new cellular evolution theory challenges Darwinian assumptions by emphasizing horizontal gene transfer as the driving force behind cellular life's evolution. This process allowed for the acquisition of alien cellular components, including genes and proteins, to promote evolutionary change.

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Genome project finds the 'triggers' for E. coli illness

A newly completed genomic sequence of E. coli O157:H7 reveals how these bacteria are armed with a wide range of genes that trigger illness. The study found large-scale genetic changes, including the ability for viruses to introduce virulent genes, making it harder to control public health threats.