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Potential to prevent and treat a common type of inflammatory arthritis advanced by the identification of new genetic links

Researchers have identified two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition disease in Americans of European and African descent. This discovery opens up promising new avenues for targeted prevention and treatment of CPPD disease, which is currently lacking effective options.

SourceElsevier·JournalAnnals of the Rheumatic Diseases·TypeData/statistical analysis·DateMay 28, 2025