Researchers developed a new method to study long-distance DNA regulation in rare immune cells, uncovering previously hidden connections relevant to autoimmune diseases. The approach prioritized over 100 candidate genes linked to Crohn's disease risk, including CLN3, which was not typically associated with the condition.
SourceCincinnati Children's Hospital Medical Center·JournalNature Genetics·TypeData/statistical analysis·DateAug 4, 2026
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers at La Jolla Institute for Immunology discovered that immune cells in lung tissue express genes associated with autoimmune disease risk. These tissue-resident immune cells may actively drive the development of autoimmune diseases, particularly in women.
SourceLa Jolla Institute for Immunology·JournalNature Immunology·TypeExperimental study·DateAug 3, 2026
The Alliance QUANTUM trial is testing whether post-transplant consolidation therapy with teclistamab improves survival in patients with primary plasma cell leukemia. Plasma cell leukemia is a rare but aggressive blood cancer with poor long-term survival rates.
SourceAlliance for Clinical Trials in Oncology·TypeRandomized controlled/clinical trial·DateJul 30, 2026
A new atlas has been developed to map the potential of genes in predicting adverse drug reactions, utilizing a comprehensive analysis of genetic data from the Million Veteran Program. This genomic-led strategy aims to anticipate drug safety effects by identifying key genetic variants associated with adverse reactions.
Dr. Rui Yang receives a Burroughs Wellcome Fund Career Award for Medical Scientists to uncover genetic causes of life-threatening immune disorders and identify new treatment paths. The research aims to advance diagnosis and understanding of rare diseases while fostering the next generation of scientists.
A study published in PLOS Medicine found that British Bangladeshi and British Pakistani individuals are more likely to develop multimorbidity, a condition where people experience multiple chronic illnesses simultaneously. The research identified sociodemographic and genetic factors that increase the risk of developing these conditions,...
SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 9, 2026
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The new journal features cutting-edge research across basic, clinical, and translational immunology. It is designed to connect researchers across the full breadth of immunology, deepening understanding of the immune system in health and disease.
Researchers discover that kidney cancer cells lacking the tumor suppressor gene SETD2 become highly dependent on protein BCL-xL for survival. By targeting this dependency, they can selectively eliminate SETD2-deficient cancer cells, offering a potential new therapeutic strategy for patients with aggressive subset of kidney cancers.
SourceMedical University of South Carolina·JournalCancer Research·TypeExperimental study·DateJun 29, 2026
Scientists have identified a unique chimeric RNA called UBA1-CDK16 that plays important roles in women's blood cell development and disease severity. The findings suggest the chimeric RNA may serve as a natural brake to protect women from excessive autoimmune activity.
Researchers at UT MD Anderson Cancer Center have made significant advancements in targeted therapy treatments for advanced lung cancer and early-stage classical Hodgkin lymphoma. The studies showcase high response rates with novel combination therapies and a new understanding of how an enzyme affects infertility and cancer progression.
SourceUniversity of Texas M. D. Anderson Cancer Center·DateMay 5, 2026
A transcription factor phosphorylation switch, OsAHL23, dynamically balances immune responses and growth in rice. The switch is precisely controlled by the kinase OsMPK5 and phosphatase PP2A-A.
SourceScience China Press·JournalScience Bulletin·DateMar 26, 2026
AmScope B120C-5M Compound Microscope
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Researchers studied the Seychelles warbler's gut bacteria, finding that immune genes influence which microbes thrive, and that this relationship affects host health and survival. The study suggests a two-way relationship between immune genes and gut bacteria, with potential benefits for human health and disease prevention.
SourceUniversity of East Anglia·JournalMicrobiome·TypeObservational study·DateMar 11, 2026
A new Immunology Center will accelerate discoveries in muscle immunology and immune responses to gene therapies. Klaudia Kuranda brings expertise in immunology, onco-immunology, and leadership experience to the center.
A study found that age, biological sex, and human genetic factors determine the quantity and specificity of antibodies produced in response to viral infections. The research has significant implications for vaccine and therapeutic design, as it shows that individual profiles can be tailored to improve treatment effectiveness.
SourceInstitut Pasteur·JournalNature Immunology·TypeCase study·DateFeb 18, 2026
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers have developed a breakthrough technique to transform a patient's own T cells into soldiers trained to recognize and kill cancer cells, benefiting tens of thousands of individuals with blood cancers. The approach is now being explored for solid tumors and other diseases.
Researchers at Salk Institute debut an epigenetic catalog that shows genetic inheritance and life experiences have distinct effects on various types of immune cells, shedding light on individual differences in immune responses and potential new personalized therapeutics.
SourceSalk Institute·JournalNature Genetics·DateJan 27, 2026
Researchers at MD Anderson have made significant advancements in cancer treatment, demonstrating the effectiveness of immunotherapy before and after surgery in improving lung cancer patient outcomes. Additionally, a new study shows promise in using CAR T cell therapy to treat large B-cell lymphoma, reducing relapse rates.
SourceUniversity of Texas M. D. Anderson Cancer Center·DateJan 9, 2026
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Researchers at La Jolla Institute for Immunology discovered that ALS is likely caused by an autoimmune reaction triggered by inflammatory CD4+ T cells targeting specific proteins in the nervous system. Anti-inflammatory CD4+ T cells may slow disease progression and prolong survival times.
SourceLa Jolla Institute for Immunology·JournalNature·TypeExperimental study·DateOct 1, 2025
Researchers mapped the surface envelope glycoprotein of human endogenous retroviruses, opening doors to new diagnostic and therapeutic opportunities. The study revealed specific antibodies that target the viral proteins, potentially leading to new cancer immunotherapies and treatments for autoimmune diseases.
SourceLa Jolla Institute for Immunology·JournalScience Advances·TypeExperimental study·DateAug 27, 2025
A new study found that a gene passed down from extinct archaic humans, Denisovans, is present in modern Latin Americans with Indigenous American ancestry and provides an adaptive advantage. The researchers also discovered the gene's presence in ancient individuals excavated at archeological sites across North and South America.
SourceBrown University·JournalScience·TypeExperimental study·DateAug 21, 2025
The new Epigraph vaccine developed by University of Nebraska-Lincoln virologist Eric Weaver protects against H1N1 swine flu and can also protect against influenza in humans and birds. The vaccine significantly outperformed commercial vaccines, providing protection for up to a decade.
SourceUniversity of Nebraska-Lincoln·JournalNature Communications·TypeExperimental study·DateMay 12, 2025
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers at Salk Institute establish a novel framework for the relationship between nutrition and cell identity. They found that a nutritional switch from acetate to citrate plays a key role in determining T cell fates, shifting them from active effector cells to exhausted cells.
Researchers found impaired PD-1 activity can significantly reduce antibody diversity and quality in memory B cells. This may explain the increased rates of infection reported in patients with cancer receiving checkpoint inhibitor therapy.
SourceGarvan Institute of Medical Research·JournalImmunity·TypeExperimental study·DateNov 26, 2024
Researchers have created the first spatial map of malaria infection in the mouse liver using Spatial Transcriptomics and single-cell RNA-sequencing. This discovery sheds light on the parasite's lifecycle, revealing changes in host cell gene expression near infected areas.
SourceStockholm University·JournalNature Communications·TypeExperimental study·DateAug 19, 2024
Researchers have developed a gene editing technique that can repair defective immune cells using CRISPR-Cas9, showing promise in treating rare diseases like Familial Hemophagocytic Lymphohistiocytosis. The therapy involves repairing genetic defects in cytotoxic T cells to normalize the immune response.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalScience Immunology·TypeExperimental study·DateFeb 2, 2024
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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers uncover a link between hyperactive Rac2 and human immune deficiency, shedding light on a mysterious condition. They also find promise in using cellular cannibalism to enhance cancer treatment.
SourceUniversity of California - Santa Barbara·JournalProceedings of the National Academy of Sciences·DateJan 5, 2024
Researchers at Cold Spring Harbor Laboratory discovered that bat genomes contain unique adaptations to defend against infection and cancer. The study highlights the interconnectedness of immunity and cancer response, revealing potential new treatments for human diseases.
SourceCold Spring Harbor Laboratory·JournalGenome Biology and Evolution·DateOct 16, 2023
Researchers aim to identify genetic risk factors and mechanisms underlying virus-induced asthma, using artificial intelligence-based techniques and patient-derived models. The study may lead to personalized prevention campaigns and mechanism-targeted drugs.
SourceUniversity Medical Center Utrecht·DateSep 1, 2023
Researchers developed a novel vaccine against SARS-CoV-2 by selecting antigen variants with low binding affinity, resulting in higher neutralizing antibody concentrations. This design strategy may also improve vaccine efficacy for other coronaviruses and herpes viruses.
SourceBIH at Charité·JournalEuropean Journal of Immunology·TypeExperimental study·DateJul 26, 2023
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A new study reveals that a common genetic variant among people, HLA-B*15:01, is responsible for mediating asymptomatic SARS-CoV-2 infection. Individuals with this variant can quickly kill infected cells due to cross-reactive immunological responses, allowing them to avoid symptoms.
SourceUniversity of North Carolina at Charlotte·JournalNature·DateJul 19, 2023
A recent study has elucidated the genetic factors involved in systemic lupus erythematosus (SLE) development. The researchers found that HLA-DRB1*15:01 is primarily associated with SLE development in the Japanese population, suggesting its role in influencing disease progression. Furthermore, the study highlights the importance of anal...
SourceUniversity of Tsukuba·JournalRMD Open·DateJul 4, 2023
Researchers found specific HLA molecules linked to MPO-AAV susceptibility and increased risk of relapse, potentially leading to precision medicine solutions for treatment. Biomarkers may be developed to predict relapse risk, improving patient outcomes.
SourceUniversity of Tsukuba·JournalFrontiers in Immunology·DateMay 25, 2023
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
SourceXi'an Jiaotong-Liverpool University·JournalNano Letters·TypeExperimental study·DateMay 8, 2023
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A protein called PI3K plays a crucial role in immune cell function, and genetic variations disrupting its signalling have been identified as the root cause of two immunodeficiency disorders. The study reveals how minor disruptions in immune cell signalling can lead to immune deficiency or dysfunction.
SourceGarvan Institute of Medical Research·JournalJournal of Experimental Medicine·TypeExperimental study·DateMar 21, 2023
The study reveals that repeated mutations in the sarZ gene lead to increased severity of MRSA blood stream infections, and that surface protein ClfB plays a critical role in pathogenesis. The findings provide insights into the factors contributing to MRSA virulence and may help uncover new treatment approaches.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalCell Host & Microbe·TypeExperimental study·DateJan 20, 2023
Researchers from the Netherlands Cancer Institute have discovered a new 'mystery gene' responsible for maturing the actin protein, a main component of the cell skeleton. The findings shed light on the complex process by which proteins are completed and functional in cells, with potential implications for understanding muscle diseases.
SourceNetherlands Cancer Institute·JournalScience·DateSep 29, 2022
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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers found that the APOE4 gene variant associated with Alzheimer's disease decreases risk of glaucoma by blocking a disease cascade. They also identified a potential treatment strategy using Galectin-3 inhibitors to prevent vision loss in mice with glaucoma.
SourceMass Eye and Ear·JournalImmunity·TypeExperimental study·DateAug 16, 2022
Researchers at Harvard's Wyss Institute identified genes and molecular pathways that control tolerance to pathogens in frog embryos, which are also found in mammals. The study suggests that increasing tolerance to pathogens could be an effective way to prevent death and disease without exacerbating antibiotic resistance.
SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalAdvanced Science·TypeExperimental study·DateJun 16, 2022
Researchers identify genetic determinants of immune phenotypes in type 1 diabetes, highlighting 11 genes as potential candidates for new treatments. Genetic variants affecting T-cell composition and cytokine production were found to be significantly involved in the disease.
A study from North Carolina State University found that critically endangered Wyoming toads have low genetic diversity in their immune systems, which could impact their ability to respond to new pathogens. The findings inform captive breeding strategies for endangered animal populations.
SourceNorth Carolina State University·JournalConservation Genetics·TypeExperimental study·DateApr 28, 2022
Researchers analyzed genomic profiles of over one million cells from 1,000 people, identifying a link between specific genes and immune cell types in autoimmune diseases. The discovery could lead to tailored treatments and refine clinical trials.
SourceGarvan Institute of Medical Research·JournalScience·DateApr 7, 2022
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers used identical twins to exclude genetic influences and track immune system changes responsible for triggering multiple sclerosis. The study found that an error in the communication of immune cells leads to greater activation of T cells, causing damage in the central nervous system.
Researchers investigated cytokine production in healthy Tanzanian adults, revealing genetic and immunological differences with European populations. The study highlights the need for more research on non-European populations to gain a full understanding of human immune system diversity.
SourceRadboud University Medical Center·JournalAmerican Journal of Human Genetics·TypeSurvey·DateFeb 14, 2022
Scientists at Washington State University have discovered a novel theory that the innate immune system can respond differently to specific pathogens. This quality, known as immunological specificity, is driven by the nervous system and could provide a basis for finetuning an experimental treatment to fight infection.
SourceWashington State University·JournalCell Reports·TypeExperimental study·DateFeb 8, 2022
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The Sanford Children's Genomic Medicine Consortium has initiated a whole genome sequencing research project to investigate undiagnosed illnesses in children with suspected inborn errors of immunity. The study aims to sequence the genomes of up to 25 patient genomes and learn information that can benefit patients and others.
A genetic variation among some Greenlanders makes sugar healthy by converting it into a short-chain fatty acid called acetate, which boosts the immune system. Adult carriers have lower BMI, weight, and fat percentage, while children may experience negative consequences from consuming sugar.
SourceUniversity of Copenhagen - Faculty of Science·JournalGastroenterology·DateDec 22, 2021
A UCL-led research team has identified an anti-viral gene that increases the risk of both Alzheimer's disease and severe Covid-19. The study found that a specific variant of the OAS1 gene amplifies inflammation in the brain, highlighting the importance of the immune system in both conditions.
SourceUniversity College London·JournalBrain·TypeObservational study·DateOct 7, 2021